m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00380)
Target Name Ras-related protein Rab-22A (RAB22A)
Synonyms
Rab-22; RAB22
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Gene Name RAB22A
Chromosomal Location 20q13.32
Family small GTPase superfamily; Rab family
Function
Plays a role in endocytosis and intracellular protein transport. Mediates trafficking of TF from early endosomes to recycling endosomes. Required for NGF-mediated endocytosis of NTRK1, and subsequent neurite outgrowth. Binds GTP and GDP and has low GTPase activity. Alternates between a GTP-bound active form and a GDP-bound inactive form.
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Gene ID 57403
Uniprot ID
RB22A_HUMAN
HGNC ID
HGNC:9764
Ensembl Gene ID
ENSG00000124209
KEGG ID
hsa:57403
References
Ref 1 METTL14 mediated m6A modification to LncRNA ZFAS1/ RAB22A: A novel therapeutic target for atherosclerosis. Int J Cardiol. 2021 Apr 1;328:177. doi: 10.1016/j.ijcard.2020.12.002. Epub 2020 Dec 8.