m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00220)
Target Name Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1B)
Synonyms
CPT1-M; Carnitine O-palmitoyltransferase I, muscle isoform; CPT I; CPTI-M; Carnitine palmitoyltransferase 1B; Carnitine palmitoyltransferase I-like protein; KIAA1670
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Gene Name CPT1B
Chromosomal Location 22q13.33
Family carnitine/choline acetyltransferase family
Gene ID 1375
Uniprot ID
CPT1B_HUMAN
HGNC ID
HGNC:2329
Ensembl Gene ID
ENSG00000205560
KEGG ID
hsa:1375
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
CPT1B can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
Browse Disease
Solid tumour/cancer [ICD-11: 2A00-2F9Z]
 Disease Info 
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response []
Response Summary m6A induced ERR-Gamma confers chemoresistance of cancer cells through upregulation of ABCB1 and Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1B).
Responsed Disease Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Pathway Response ABC transporters hsa02010
Fatty acid metabolism hsa01212
Fatty acid degradation hsa00071
Cell Process Fatty acid oxidation
In-vitro Model ()
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In-vivo Model Both sh-control and sh- ERRγ HepG2/ADR cells (5 × 106 per mouse, n=5 for each group) were diluted in 200uL PBS + 200 uL Matrigel (BD Biosciences) and subcutaneously injected into immunodeficient mice.