m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00105)
Target Name Long intergenic non-protein coding RNA 278 (LINC00278)
Synonyms
LINC00278; NCRNA00278; non-protein coding RNA 278; YY1BM; YY1-blocking micropeptide
    Click to Show/Hide
Gene Name LINC00278
Chromosomal Location Yp11.31
Family Long intergenic non-protein coding RNAs
Gene ID 100873962
HGNC ID
HGNC:38712
Ensembl Gene ID
ENSG00000231535
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
LINC00278 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
Browse Disease
Oral cavity/oesophagus/stomach in situ carcinoma [ICD-11: 2E60]
 Disease Info 
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response []
Response Summary Downregulation of YY1BM significantly upregulated eEF2K expression and inhibited apoptosis, thus conferring esophageal squamous cell carcinoma cells more adaptive to nutrient deprivation. Cigarette smoking decreased m6A modification of Long intergenic non-protein coding RNA 278 (LINC00278) and YY1BM translation.
Responsed Disease Esophageal squamous cell carcinoma [ICD-11: 2B70.1]
Cell Process Nutrient deprivation
Cell apoptosis
In-vitro Model ()
()
()
()
()
In-vivo Model Injected YY1BM intratumorally into ESCC tumors grafted in nude mice and analyzed the survival time.