General Information of the m6A Target Gene (ID: M6ATAR00006)
Target Name Circ_104075
Synonyms
Circ-104075
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Gene Name Circ_104075
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
Circ_104075 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
Browse Disease
Liver cancer [ICD-11: 2C12]
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response []
Response Summary N6-methyladenosine (m6A) motif was identified in the 353-357 region of YAP 3'UTR, and this m6A modification was essential for the interaction between miR-582-3p and YAP 3'UTR. And targeting Circ_104075 provides new strategies in HCC diagnosis and therapy.
Responsed Disease Hepatocellular carcinoma [ICD-11: 2C12.02]
Cell Process RNA stability
In-vitro Model ()
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In-vivo Model HNF4a knockout (HNF4a-/-) mice were generated using CRISPR/Cas9 in C57BL/6 mice.