RNA-seq Results

Results indicating the target gene (PDK4 ) expression regulated by m6A regulator (METTL3 )
2B91: Colorectal cancer
In total 1 results
Result 1 indicating the PDK4 expression regulated by METTL3
Cell Line Caco-2 cell line CVCL_0025
Condition Colorectal adenocarcinoma Homo sapiens
Treatment: shMETTL3 Caco-2 cells
Control: shNTC Caco-2 cells
 GSE167075
Regulation
logFC: -2.38E+00
 p-value: 3.20E-03
2C60: Breast cancer
In total 1 results
Result 1 indicating the PDK4 expression regulated by METTL3
Cell Line MDA-MB-231 CVCL_0062
Condition Breast cancer Homo sapiens
Treatment: METTL3 knockdown MDA-MB-231 cells
Control: MDA-MB-231 cells
 GSE70061
Regulation
logFC: -6.22E-01
 p-value: 5.96E-04
Healthy
In total 9 results
Result 1 indicating the PDK4 expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3 knockout liver
Control: Wild type liver cells
 GSE198513
Regulation
logFC: 7.49E-01
 p-value: 2.60E-19
Result 2 indicating the PDK4 expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3-deficient liver
Control: Wild type liver cells
 GSE197800
Regulation
logFC: 2.08E+00
 p-value: 3.13E-04
Result 3 indicating the PDK4 expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3 knockout liver
Control: Wild type liver cells
 GSE198512
Regulation
logFC: 6.44E+00
 p-value: 1.10E-03
Result 4 indicating the PDK4 expression regulated by METTL3
Cell Line Pancreatic islets
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mice
Control: Mettl3 flox/flox mice
 GSE155612
Regulation
logFC: 1.23E+00
 p-value: 4.61E-03
Result 5 indicating the PDK4 expression regulated by METTL3
Cell Line LX2 cell line CVCL_5792
Condition Healthy Homo sapiens
Treatment: shMETTL3 LX2 cells
Control: shLuc LX2 cells
 GSE207909
Regulation
logFC: -1.03E+01
 p-value: 3.59E-12
Result 6 indicating the PDK4 expression regulated by METTL3
Cell Line ARPE-19 cell line CVCL_0145
Condition Healthy Homo sapiens
Treatment: shMETTL3 ARPE-19 cells
Control: shControl ARPE-19 cells
 GSE202017
Regulation
logFC: 8.16E-01
 p-value: 5.76E-04
Result 7 indicating the PDK4 expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3 knockout ESCs
Control: Wild type ESCs
 GSE146466
Regulation
logFC: 1.52E+00
 p-value: 6.67E-08
Result 8 indicating the PDK4 expression regulated by METTL3
Cell Line Bone-marrow-derived macrophages
Condition Healthy Mus musculus
Treatment: Mettl3fl/fl (KO) BMDMs
Control: Wild type BMDMs
 GSE182865
Regulation
logFC: -2.14E+00
 p-value: 1.18E-03
Result 9 indicating the PDK4 expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3 knockout mESCs
Control: Wild type mESCs
 GSE156481
Regulation
logFC: -1.03E+00
 p-value: 4.99E-02