Results indicating the target gene (IL-6 ) expression regulated by m6A regulator (METTL3 )
2B33: Malignant haematopoietic neoplasm
In total 1 results
Result 1 indicating the IL-6 expression regulated by METTL3
Cell Line Raw 264.7 cell line CVCL_0493
Condition Leukemia Mus musculus
Treatment: METTL3 knockout Raw 264.7 cells
Control: Wild type Raw 264.7 cells
GSE162248
Regulation
logFC: -5.08E+00
p-value: 2.74E-134
Healthy
In total 5 results
Result 1 indicating the IL-6 expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3 knockout liver
Control: Wild type liver cells
GSE198513
Regulation
logFC: 1.25E+00
p-value: 1.33E-08
Result 2 indicating the IL-6 expression regulated by METTL3
Cell Line ARPE-19 cell line CVCL_0145
Condition Healthy Homo sapiens
Treatment: shMETTL3 ARPE-19 cells
Control: shControl ARPE-19 cells
GSE202017
Regulation
logFC: -1.10E+00
p-value: 7.68E-04
Result 3 indicating the IL-6 expression regulated by METTL3
Cell Line LX2 cell line CVCL_5792
Condition Healthy Homo sapiens
Treatment: shMETTL3 LX2 cells
Control: shLuc LX2 cells
GSE207909
Regulation
logFC: -8.38E-01
p-value: 4.61E-02
Result 4 indicating the IL-6 expression regulated by METTL3
Cell Line Mesenchymal stem cell line
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mesenchymal stem cells
Control: Wild type mesenchymal stem cells
GSE114933
Regulation
logFC: -2.78E+00
p-value: 3.15E-04
Result 5 indicating the IL-6 expression regulated by METTL3
Cell Line Th1 cell line CVCL_5J51
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Th1 cells
Control: Wild type splenic Th1 cells
GSE129648
Regulation
logFC: 1.72E+00
p-value: 2.27E-02