Results indicating the target gene (POLK ) expression regulated by m6A regulator (METTL3 )
2B90: Colon cancer
In total 1 results
Result 1 indicating the POLK expression regulated by METTL3
Cell Line CT26 cell line CVCL_7254
Condition Colon adenocarcinoma Mus musculus
Treatment: METTL3 knockout CT26 cells
Control: CT26 cells
GSE142589
Regulation
logFC: -8.59E-01
p-value: 4.55E-03
Healthy
In total 6 results
Result 1 indicating the POLK expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3 knockout liver
Control: Wild type liver cells
GSE198513
Regulation
logFC: 7.13E-01
p-value: 8.82E-11
Result 2 indicating the POLK expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3-deficient liver
Control: Wild type liver cells
GSE197800
Regulation
logFC: 1.20E+00
p-value: 1.34E-06
Result 3 indicating the POLK expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3 knockout liver
Control: Wild type liver cells
GSE198512
Regulation
logFC: 2.16E+00
p-value: 6.18E-04
Result 4 indicating the POLK expression regulated by METTL3
Cell Line Pancreatic islets
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mice
Control: Mettl3 flox/flox mice
GSE155612
Regulation
logFC: 1.06E+00
p-value: 1.38E-03
Result 5 indicating the POLK expression regulated by METTL3
Cell Line mouse embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3-/- ESCs
Control: Wild type ESCs
GSE145309
Regulation
logFC: 8.09E-01
p-value: 1.19E-26
Result 6 indicating the POLK expression regulated by METTL3
Cell Line Th1 cell line CVCL_5J51
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Th1 cells
Control: Wild type splenic Th1 cells
GSE129648
Regulation
logFC: 6.15E-01
p-value: 3.63E-02