Results indicating the target gene (MYC ) expression regulated by m6A regulator (METTL3 )
2B90: Colon cancer
In total 1 results
Result 1 indicating the MYC expression regulated by METTL3
Cell Line CT26 cell line CVCL_7254
Condition Colon adenocarcinoma Mus musculus
Treatment: METTL3 knockout CT26 cells
Control: CT26 cells
GSE142589
Regulation
logFC: -1.00E+00
p-value: 5.70E-03
2B91: Colorectal cancer
In total 1 results
Result 1 indicating the MYC expression regulated by METTL3
Cell Line Caco-2 cell line CVCL_0025
Condition Colorectal adenocarcinoma Homo sapiens
Treatment: shMETTL3 Caco-2 cells
Control: shNTC Caco-2 cells
GSE167075
Regulation
logFC: -7.52E-01
p-value: 3.35E-28
2C82: Prostate cancer
In total 1 results
Result 1 indicating the MYC expression regulated by METTL3
Cell Line LNCaP cell line CVCL_0395
Condition Prostate carcinoma Homo sapiens
Treatment: shMETTL3 LNCaP cells
Control: shControl LNCaP cells
GSE147884
Regulation
logFC: -6.39E-01
p-value: 4.30E-103
Healthy
In total 9 results
Result 1 indicating the MYC expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3-deficient liver
Control: Wild type liver cells
GSE197800
Regulation
logFC: 2.40E+00
p-value: 6.85E-06
Result 2 indicating the MYC expression regulated by METTL3
Cell Line Pancreatic islets
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mice
Control: Mettl3 flox/flox mice
GSE155612
Regulation
logFC: 1.75E+00
p-value: 1.45E-05
Result 3 indicating the MYC expression regulated by METTL3
Cell Line ARPE-19 cell line CVCL_0145
Condition Healthy Homo sapiens
Treatment: shMETTL3 ARPE-19 cells
Control: shControl ARPE-19 cells
GSE202017
Regulation
logFC: -6.91E-01
p-value: 2.64E-05
Result 4 indicating the MYC expression regulated by METTL3
Cell Line E14.5 LSK cell line
Condition Healthy Mus musculus
Treatment: METTL3 knockout E14.5 LSK cells
Control: Wild type E14.5 LSK cells
GSE148882
Regulation
logFC: 8.82E-01
p-value: 1.23E-24
Result 5 indicating the MYC expression regulated by METTL3
Cell Line mouse embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3-/- ESCs
Control: Wild type ESCs
GSE145309
Regulation
logFC: -6.31E-01
p-value: 4.65E-16
Result 6 indicating the MYC expression regulated by METTL3
Cell Line Th1 cell line CVCL_5J51
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Th1 cells
Control: Wild type splenic Th1 cells
GSE129648
Regulation
logFC: 1.00E+00
p-value: 1.31E-10
Result 7 indicating the MYC expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3 knockout ESCs
Control: Wild type ESCs
GSE146466
Regulation
logFC: 9.37E-01
p-value: 1.03E-05
Result 8 indicating the MYC expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3-/- mESCs
Control: Wild type ESCs
GSE147849
Regulation
logFC: -2.62E+00
p-value: 4.85E-05
Result 9 indicating the MYC expression regulated by METTL3
Cell Line Tfh cell line
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Tfh cells
Control: Wild type splenic Tfh cells
GSE129648
Regulation
logFC: 7.37E-01
p-value: 1.29E-02