Results indicating the target gene (MGMT ) expression regulated by m6A regulator (METTL3 )
2B33: Malignant haematopoietic neoplasm
In total 1 results
Result 1 indicating the MGMT expression regulated by METTL3
Cell Line Raw 264.7 cell line CVCL_0493
Condition Leukemia Mus musculus
Treatment: METTL3 knockout Raw 264.7 cells
Control: Wild type Raw 264.7 cells
GSE162248
Regulation
logFC: 7.66E-01
p-value: 6.45E-04
Healthy
In total 7 results
Result 1 indicating the MGMT expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3 knockout liver
Control: Wild type liver cells
GSE198512
Regulation
logFC: 1.15E+00
p-value: 4.52E-03
Result 2 indicating the MGMT expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3 knockout liver
Control: Wild type liver cells
GSE198513
Regulation
logFC: 6.96E-01
p-value: 5.12E-03
Result 3 indicating the MGMT expression regulated by METTL3
Cell Line Pancreatic islets
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mice
Control: Mettl3 flox/flox mice
GSE155612
Regulation
logFC: 9.11E-01
p-value: 7.41E-03
Result 4 indicating the MGMT expression regulated by METTL3
Cell Line mouse embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3-/- ESCs
Control: Wild type ESCs
GSE145309
Regulation
logFC: -1.79E+00
p-value: 2.16E-20
Result 5 indicating the MGMT expression regulated by METTL3
Cell Line Tfh cell line
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Tfh cells
Control: Wild type splenic Tfh cells
GSE129648
Regulation
logFC: 1.88E+00
p-value: 8.38E-05
Result 6 indicating the MGMT expression regulated by METTL3
Cell Line Th1 cell line CVCL_5J51
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Th1 cells
Control: Wild type splenic Th1 cells
GSE129648
Regulation
logFC: 2.29E+00
p-value: 4.45E-04
Result 7 indicating the MGMT expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3-/- mESCs
Control: Wild type ESCs
GSE147849
Regulation
logFC: -7.74E-01
p-value: 1.53E-02