RNA-seq Results

Results indicating the target gene (LEF1 ) expression regulated by m6A regulator (METTL3 )
2B91: Colorectal cancer
In total 1 results
Result 1 indicating the LEF1 expression regulated by METTL3
Cell Line Caco-2 cell line CVCL_0025
Condition Colorectal adenocarcinoma Homo sapiens
Treatment: shMETTL3 Caco-2 cells
Control: shNTC Caco-2 cells
 GSE167075
Regulation
logFC: 6.28E-01
 p-value: 2.52E-06
2C60: Breast cancer
In total 1 results
Result 1 indicating the LEF1 expression regulated by METTL3
Cell Line MDA-MB-231 CVCL_0062
Condition Breast cancer Homo sapiens
Treatment: METTL3 knockdown MDA-MB-231 cells
Control: MDA-MB-231 cells
 GSE70061
Regulation
logFC: -9.36E-01
 p-value: 2.63E-03
Healthy
In total 9 results
Result 1 indicating the LEF1 expression regulated by METTL3
Cell Line Pancreatic islets
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mice
Control: Mettl3 flox/flox mice
 GSE155612
Regulation
logFC: 9.85E-01
 p-value: 6.69E-03
Result 2 indicating the LEF1 expression regulated by METTL3
Cell Line ARPE-19 cell line CVCL_0145
Condition Healthy Homo sapiens
Treatment: shMETTL3 ARPE-19 cells
Control: shControl ARPE-19 cells
 GSE202017
Regulation
logFC: -7.69E-01
 p-value: 6.20E-04
Result 3 indicating the LEF1 expression regulated by METTL3
Cell Line mouse embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3-/- ESCs
Control: Wild type ESCs
 GSE145309
Regulation
logFC: 3.15E+00
 p-value: 0.00E+00
Result 4 indicating the LEF1 expression regulated by METTL3
Cell Line Tfh cell line
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Tfh cells
Control: Wild type splenic Tfh cells
 GSE129648
Regulation
logFC: -1.50E+00
 p-value: 1.21E-14
Result 5 indicating the LEF1 expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3 knockout ESCs
Control: Wild type ESCs
 GSE146466
Regulation
logFC: 1.43E+00
 p-value: 1.35E-06
Result 6 indicating the LEF1 expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3 knockout mESCs
Control: Wild type mESCs
 GSE156481
Regulation
logFC: 3.27E+00
 p-value: 9.44E-06
Result 7 indicating the LEF1 expression regulated by METTL3
Cell Line E14.5 LSK cell line
Condition Healthy Mus musculus
Treatment: METTL3 knockout E14.5 LSK cells
Control: Wild type E14.5 LSK cells
 GSE148882
Regulation
logFC: -1.74E+00
 p-value: 5.54E-05
Result 8 indicating the LEF1 expression regulated by METTL3
Cell Line Mesenchymal stem cell line
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mesenchymal stem cells
Control: Wild type mesenchymal stem cells
 GSE114933
Regulation
logFC: 1.01E+00
 p-value: 3.26E-03
Result 9 indicating the LEF1 expression regulated by METTL3
Cell Line Th1 cell line CVCL_5J51
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Th1 cells
Control: Wild type splenic Th1 cells
 GSE129648
Regulation
logFC: -6.51E-01
 p-value: 1.97E-02