Results indicating the target gene (HIF1A ) expression regulated by m6A regulator (METTL3 )
Healthy
In total 6 results
Result 1 indicating the HIF1A expression regulated by METTL3
Cell Line Pancreatic islets
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mice
Control: Mettl3 flox/flox mice
GSE155612
Regulation
logFC: 8.47E-01
p-value: 1.25E-03
Result 2 indicating the HIF1A expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3-deficient liver
Control: Wild type liver cells
GSE197800
Regulation
logFC: -5.89E-01
p-value: 2.56E-03
Result 3 indicating the HIF1A expression regulated by METTL3
Cell Line LX2 cell line CVCL_5792
Condition Healthy Homo sapiens
Treatment: shMETTL3 LX2 cells
Control: shLuc LX2 cells
GSE207909
Regulation
logFC: 1.13E+00
p-value: 4.17E-08
Result 4 indicating the HIF1A expression regulated by METTL3
Cell Line ARPE-19 cell line CVCL_0145
Condition Healthy Homo sapiens
Treatment: shMETTL3 ARPE-19 cells
Control: shControl ARPE-19 cells
GSE202017
Regulation
logFC: 8.76E-01
p-value: 1.04E-05
Result 5 indicating the HIF1A expression regulated by METTL3
Cell Line Tfh cell line
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Tfh cells
Control: Wild type splenic Tfh cells
GSE129648
Regulation
logFC: -1.25E+00
p-value: 2.38E-10
Result 6 indicating the HIF1A expression regulated by METTL3
Cell Line Th1 cell line CVCL_5J51
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Th1 cells
Control: Wild type splenic Th1 cells
GSE129648
Regulation
logFC: 6.39E-01
p-value: 5.68E-05