General Information of the m6A Regulator (ID: REG00032)
Regulator Name E3 ubiquitin-protein ligase Hakai (CBLL1)
Synonyms
CBLL1; HAKAI; RNF188; EC 2.3.2.27; Casitas B-lineage lymphoma-transforming sequence-like protein 1; c-Cbl-like protein 1; RING finger protein 188; RING-type E3 ubiquitin transferase Hakai
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Gene Name CBLL1
Regulator Type ERASER READER WRITER
Regulator Link Click to View Full Information of This Regulator
Full List of Target Gene(s) of This m6A Regulator ( Full Data Download )
Protein coding
Gene with protein product
In total 601 target gene(s)
5'-nucleotidase ecto (NT5E) [1]
HGNC ID HGNC:8021
Ensembl ID ENSG00000135318
Uniprot ID 5NTD_HUMAN
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: -0.701655418; p-value: 0.00421697
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Actin alpha 2, smooth muscle (ACTA2) [1]
HGNC ID HGNC:130
Ensembl ID ENSG00000107796
Uniprot ID ACTA_HUMAN
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 2.422433259; p-value: 3.86E-06
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Actin related protein T3 (ACTRT3) [1]
HGNC ID HGNC:24022
Ensembl ID ENSG00000184378
Uniprot ID ACTT3_HUMAN
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 0.614481676; p-value: 0.022401282
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Acyl-CoA synthetase medium chain family member 3 (ACSM3) [1]
HGNC ID HGNC:10522
Ensembl ID ENSG00000005187
Uniprot ID ACSM3_HUMAN
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 0.849612522; p-value: 0.013183645
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
ADAM metallopeptidase domain 19 (ADAM19) [1]
HGNC ID HGNC:197
Ensembl ID ENSG00000135074
Uniprot ID ADA19_HUMAN
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 0.671808217; p-value: 0.018879425
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
ADAM metallopeptidase domain 9 (ADAM9) [1]
HGNC ID HGNC:216
Ensembl ID ENSG00000168615
Uniprot ID ADAM9_HUMAN
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 1.06451554; p-value: 0.000303672
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
ADAM metallopeptidase with thrombospondin type 1 motif 12 (ADAMTS12) [1]
HGNC ID HGNC:14605
Ensembl ID ENSG00000151388
Uniprot ID ATS12_HUMAN
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 0.792375; p-value: 0.018105964
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
ADAMTS like 4 (ADAMTSL4) [1]
HGNC ID HGNC:19706
Ensembl ID ENSG00000143382
Uniprot ID ATL4_HUMAN
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 0.671741912; p-value: 0.001537204
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Adenosine deaminase like (ADAL) [1]
HGNC ID HGNC:31853
Ensembl ID ENSG00000168803
Uniprot ID ADAL_HUMAN
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: -0.597492929; p-value: 0.026623144
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Adenosine deaminase tRNA specific 3 (ADAT3) [1]
HGNC ID HGNC:25151
Ensembl ID ENSG00000213638
Uniprot ID ADAT3_HUMAN
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 1.528681146; p-value: 0.000126909
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Click to Download All Target Gene of This Genetic Class
Pseudogene
Pseudogene
In total 39 target gene(s)
Actin gamma 1 pseudogene 20 (ACTG1P20) [1]
HGNC ID HGNC:51500
Ensembl ID ENSG00000241547
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 1.15685409; p-value: 0.001831544
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
ATP binding cassette subfamily C member 6 pseudogene 2 (ABCC6P2) [1]
HGNC ID HGNC:33353
Ensembl ID ENSG00000255277
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: -1.218670136; p-value: 2.48E-26
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
BCR pseudogene 3 (BCRP3) [1]
HGNC ID HGNC:1016
Ensembl ID ENSG00000215481
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 1.678179637; p-value: 0.000664126
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
CDRT15 pseudogene 4 (CDRT15P4) [1]
HGNC ID HGNC:54913
Ensembl ID ENSG00000287071
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 3.563501333; p-value: 7.41E-05
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene (CMAHP) [1]
HGNC ID HGNC:2098
Ensembl ID ENSG00000168405
Uniprot ID CMAH_HUMAN
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: -0.620516406; p-value: 0.007623764
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Family with sequence similarity 3 member C2, pseudogene (FAM3C2P) [1]
HGNC ID HGNC:34501
Ensembl ID ENSG00000174028
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: -0.663849063; p-value: 0.007067682
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
FCF1 pseudogene 2 (FCF1P2) [1]
HGNC ID HGNC:44614
Ensembl ID ENSG00000228638
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 0.649121049; p-value: 0.026769392
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Heterogeneous nuclear ribonucleoprotein C pseudogene 1 (HNRNPCP1) [1]
HGNC ID HGNC:20017
Ensembl ID ENSG00000258900
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: -2.060712383; p-value: 0.004872484
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
High mobility group nucleosomal binding domain 2 pseudogene 5 (HMGN2P5) [1]
HGNC ID HGNC:33568
Ensembl ID ENSG00000234664
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: -0.744553119; p-value: 0.002413012
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
MAPK regulated corepressor interacting protein 2 pseudogene 1 (MCRIP2P1) [1]
HGNC ID HGNC:49629
Ensembl ID ENSG00000241418
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 0.797203485; p-value: 2.89E-10
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Click to Download All Target Gene of This Genetic Class
Long non-coding
Long non-coding RNA
In total 57 target gene(s)
AKAP1 divergent transcript (AKAP1-DT) [1]
HGNC ID HGNC:55339
Ensembl ID ENSG00000263004
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 6.983705955; p-value: 0.000780283
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
ALOX12 antisense RNA 1 (ALOX12-AS1) [1]
HGNC ID HGNC:51342
Ensembl ID ENSG00000215067
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 0.726967372; p-value: 7.39E-06
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
ATP2A1 antisense RNA 1 (ATP2A1-AS1) [1]
HGNC ID HGNC:51370
Ensembl ID ENSG00000260442
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: -3.288410382; p-value: 0.00986011
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Cancer susceptibility 15 (CASC15) [1]
HGNC ID HGNC:28245
Ensembl ID ENSG00000272168
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: -0.714851989; p-value: 0.003484229
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
CDC37L1 divergent transcript (CDC37L1-DT) [1]
HGNC ID HGNC:49735
Ensembl ID ENSG00000273061
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 1.456134369; p-value: 0.033890133
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
CEACAM16, CEACAM19 and PVR antisense RNA 1 (CEACAM16-AS1) [1]
HGNC ID HGNC:55317
Ensembl ID ENSG00000266903
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: -3.432823781; p-value: 0.003600622
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
CKAP2 divergent transcript (CKAP2-DT) [1]
HGNC ID HGNC:56053
Ensembl ID ENSG00000278238
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: -1.787134052; p-value: 0.002784463
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
CNN3 divergent transcript (CNN3-DT) [1]
HGNC ID HGNC:54176
Ensembl ID ENSG00000235501
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: -1.308162029; p-value: 0.008562784
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
DNM3 opposite strand/antisense RNA (DNM3OS) [1]
HGNC ID HGNC:41228
Ensembl ID ENSG00000230630
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 0.5851223; p-value: 0.000243786
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
ELN antisense RNA 1 (ELN-AS1) [1]
HGNC ID HGNC:40212
Ensembl ID ENSG00000232415
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 0.895306926; p-value: 0.003161997
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Click to Download All Target Gene of This Genetic Class
Short non-coding
Small nucleolar RNA
In total 3 target gene(s)
Small Cajal body-specific RNA 13 (SCARNA13) [1]
HGNC ID HGNC:32570
Ensembl ID ENSG00000252481
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 1.186915842; p-value: 0.012816619
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Small Cajal body-specific RNA 6 (SCARNA6) [1]
HGNC ID HGNC:32562
Ensembl ID ENSG00000251791
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 1.473085479; p-value: 0.000685092
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Small Cajal body-specific RNA 9 (SCARNA9) [1]
HGNC ID HGNC:32566
Ensembl ID ENSG00000254911
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 1.471068767; p-value: 0.017555059
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Click to Download All Target Gene of This Genetic Class
Other
Protocadherin
In total 1 target gene(s)
Protocadherin beta 5 (PCDHB5) [1]
HGNC ID HGNC:8690
Ensembl ID ENSG00000113209
Uniprot ID PCDB5_HUMAN
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: -1.430041067; p-value: 0.001984573
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Click to Download All Target Gene of This Genetic Class
Readthrough
In total 1 target gene(s)
FMC1-LUC7L2 readthrough (FMC1-LUC7L2) [1]
HGNC ID HGNC:44671
Ensembl ID ENSG00000269955
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: 0.634064544; p-value: 0.00371742
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Click to Download All Target Gene of This Genetic Class
T cell receptor gene
In total 1 target gene(s)
T cell receptor beta variable 12-4 (TRBV12-4) [1]
HGNC ID HGNC:12186
Ensembl ID ENSG00000276953
Uniprot ID TVBL4_HUMAN
Method RNA-seq GSE167067
Condition knock down
Evidence logFC: -1.794416011; p-value: 0.031041908
Cell Line Human umbilical vein endothelial cells Healthy Homo sapiens .
Click to Download All Target Gene of This Genetic Class
References
Ref 1 Wilms' tumor 1-associating protein complex regulates alternative splicing and polyadenylation at potential G-quadruplex-forming splice site sequences. J Biol Chem. 2021 Nov;297(5):101248.