m6A Target Genes of This Regulator

General Information of the m6A Regulator (ID: REG00001)
Regulator Name Fat mass and obesity-associated protein (FTO)
Synonyms
Alpha-ketoglutarate-dependent dioxygenase FTO; U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO; mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO; m6A(m)-demethylase FTO; mRNA N(6)-methyladenosine demethylase FTO; tRNA N1-methyl adenine demethylase FTO; KIAA1752
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Gene Name FTO
Regulator Type ERASER READER WRITER
Regulator Link Click to View Full Information of This Regulator
Full List of Target Gene(s) of This m6A Regulator ( Full Data Download )
Protein coding
Gene with protein product
In total 5961 target gene(s)
Acid phosphatase 5, tartrate resistant (ACP5) [1]
HGNC ID HGNC:124
Ensembl ID ENSG00000102575
Uniprot ID PPA5_HUMAN
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Adaptor related protein complex 1 subunit sigma 2 (AP1S2) [1]
HGNC ID HGNC:560
Ensembl ID ENSG00000182287
Uniprot ID AP1S2_HUMAN
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Adhesion G protein-coupled receptor V1 (ADGRV1) [1]
HGNC ID HGNC:17416
Ensembl ID ENSG00000164199
Uniprot ID AGRV1_HUMAN
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
AE binding protein 2 (AEBP2) [1]
HGNC ID HGNC:24051
Ensembl ID ENSG00000139154
Uniprot ID AEBP2_HUMAN
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Aggrecan (ACAN) [1]
HGNC ID HGNC:319
Ensembl ID ENSG00000157766
Uniprot ID PGCA_HUMAN
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
AKT serine/threonine kinase 2 (AKT2) [1]
HGNC ID HGNC:392
Ensembl ID ENSG00000105221
Uniprot ID AKT2_HUMAN
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Ankyrin repeat and KH domain containing 1 (ANKHD1) [1]
HGNC ID HGNC:24714
Ensembl ID ENSG00000131503
Uniprot ID ANKH1_HUMAN
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Arginine and glutamate rich 1 (ARGLU1) [1]
HGNC ID HGNC:25482
Ensembl ID ENSG00000134884
Uniprot ID ARGL1_HUMAN
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
ATP binding cassette subfamily C member 6 (ABCC6) [1]
HGNC ID HGNC:57
Ensembl ID ENSG00000091262
Uniprot ID MRP6_HUMAN
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
ATPase phospholipid transporting 10D (putative) (ATP10D) [1]
HGNC ID HGNC:13549
Ensembl ID ENSG00000145246
Uniprot ID AT10D_HUMAN
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Click to Download All Target Gene of This Genetic Class
Pseudogene
Immunoglobulin pseudogene
In total 1 target gene(s)
Immunoglobulin heavy variable 1/OR15-3 (pseudogene) (IGHV1OR15-3) [2]
HGNC ID HGNC:5565
Ensembl ID ENSG00000271288
Method RNA-seq GSE103494
Condition knock down
Evidence logFC: -1.857702361; p-value: 0.035062901
Cell Line NB4 Acute myeloid leukemia Homo sapiens CVCL_0005
Click to Download All Target Gene of This Genetic Class
Pseudogene
In total 434 target gene(s)
DPY19L2 pseudogene 4 (DPY19L2P4) [1]
HGNC ID HGNC:22176
Ensembl ID ENSG00000235436
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Leucine decarboxylase 1, pseudogene (LINC01225) [1]
HGNC ID HGNC:49677
Ensembl ID ENSG00000260386
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
SUZ12 pseudogene 1 (SUZ12P1) [1]
HGNC ID HGNC:32421
Ensembl ID ENSG00000264538
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Transducer of ERBB2, 2 pseudogene 1 (TOB2P1) [1]
HGNC ID HGNC:13986
Ensembl ID ENSG00000176933
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Activating transcription factor 4 pseudogene 3 (ATF4P3) [3]
HGNC ID HGNC:788
Ensembl ID ENSG00000228218
Method RNA-seq GSE150239
Condition knock down
Evidence logFC: -0.734470439; p-value: 0.003248499
Cell Line 253Jcells Bladder cancer Homo sapiens CVCL_7935
Adenosylmethionine decarboxylase 1 pseudogene 3 (AMD1P3) [1]
HGNC ID HGNC:51608
Ensembl ID ENSG00000249286
Method RNA-seq GSE79577
Condition knock out
Evidence logFC: 0.628649714; p-value: 0.00253139
Cell Line HEK293 cell line Healthy Homo sapiens CVCL_0045
Adhesion G protein-coupled receptor E4, pseudogene (ADGRE4P) [2]
HGNC ID HGNC:19240
Ensembl ID ENSG00000268758
Uniprot ID AGRE4_HUMAN
Method RNA-seq GSE103494
Condition knock down
Evidence logFC: -0.762600025; p-value: 2.23E-06
Cell Line NB4 Acute myeloid leukemia Homo sapiens CVCL_0005
ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase like (pseudogene) (ALG1L) [3]
HGNC ID HGNC:33721
Ensembl ID ENSG00000189366
Uniprot ID ALG1L_HUMAN
Method RNA-seq GSE150239
Condition knock down
Evidence logFC: 0.839208798; p-value: 2.49E-07
Cell Line 253Jcells Bladder cancer Homo sapiens CVCL_7935
ALG3 pseudogene 1 (ALG3P1) [1]
HGNC ID HGNC:45159
Ensembl ID ENSG00000251568
Method RNA-seq GSE79577
Condition knock out
Evidence logFC: -0.590022634; p-value: 1.17E-05
Cell Line HEK293 cell line Healthy Homo sapiens CVCL_0045
ALMS1 pseudogene 1 (ALMS1P1) [1]
HGNC ID HGNC:29586
Ensembl ID ENSG00000163016
Method RNA-seq GSE79577
Condition knock out
Evidence logFC: -0.848067023; p-value: 4.19E-05
Cell Line HEK293 cell line Healthy Homo sapiens CVCL_0045
Click to Download All Target Gene of This Genetic Class
Long non-coding
Long non-coding RNA
In total 550 target gene(s)
ARHGAP42 antisense RNA 1 (LOC100128386) [1]
HGNC ID HGNC:54801
Ensembl ID ENSG00000248027
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
CTBP1 antisense RNA (CTBP1-AS) [1]
HGNC ID HGNC:48337
Ensembl ID ENSG00000280927
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Firre intergenic repeating RNA element (FIRRE) [1]
HGNC ID HGNC:49627
Ensembl ID ENSG00000213468
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
FTO intronic transcript 1 (FTO-IT1) [1]
HGNC ID HGNC:43758
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
GLIS3 antisense RNA 1 (GLIS3-AS1) [1]
HGNC ID HGNC:28260
Ensembl ID ENSG00000237009
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Long intergenic non-protein coding RNA 1503 (LINC01503) [1]
HGNC ID HGNC:51184
Ensembl ID ENSG00000233901
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Long intergenic non-protein coding RNA 1549 (LINC01549) [1]
HGNC ID HGNC:1277
Ensembl ID ENSG00000232560
Uniprot ID CU037_HUMAN
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Long intergenic non-protein coding RNA 1556 (LINC01556) [1]
HGNC ID HGNC:21195
Ensembl ID ENSG00000204709
Uniprot ID CF100_HUMAN
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Long intergenic non-protein coding RNA 1623 (LINC01623) [1]
HGNC ID HGNC:52050
Ensembl ID ENSG00000225595
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Long intergenic non-protein coding RNA 1950 (LINC01950) [1]
HGNC ID HGNC:52773
Ensembl ID ENSG00000251027
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Click to Download All Target Gene of This Genetic Class
Short non-coding
Micro RNA
In total 48 target gene(s)
MicroRNA 128-1 (MIR128-1) [1]
HGNC ID HGNC:31510
Ensembl ID ENSG00000207654
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
MicroRNA 3171 (MIR3171) [1]
HGNC ID HGNC:38216
Ensembl ID ENSG00000264657
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
MicroRNA 378h (MIR378H) [1]
HGNC ID HGNC:41744
Ensembl ID ENSG00000263361
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
MicroRNA 4297 (MIR4297) [1]
HGNC ID HGNC:38393
Ensembl ID ENSG00000266676
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
MicroRNA 4455 (MIR4455) [1]
HGNC ID HGNC:41536
Ensembl ID ENSG00000263458
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
MicroRNA 4521 (MIR4521) [1]
HGNC ID HGNC:41813
Ensembl ID ENSG00000283160
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
MicroRNA 548f-2 (MIR548F2) [1]
HGNC ID HGNC:35306
Ensembl ID ENSG00000221782
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
MicroRNA 6079 (MIR6079) [1]
HGNC ID HGNC:50114
Ensembl ID ENSG00000283477
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
microRNA 663a (MIR663A) [1]
HGNC ID HGNC:32919
Ensembl ID ENSG00000284419
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
MicroRNA 6719 (MIR6719) [1]
HGNC ID HGNC:50012
Ensembl ID ENSG00000277759
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Click to Download All Target Gene of This Genetic Class
Ribosomal RNA
In total 4 target gene(s)
RNA, 18S ribosomal 5 (RNA18S5) [1]
HGNC ID HGNC:37657
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
RNA, 28S ribosomal 5 (RNA28S5) [1]
HGNC ID HGNC:37659
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
RNA, 5.8S ribosomal 5 (RNA5-8S5) [1]
HGNC ID HGNC:37660
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
RNA, 5.8S ribosomal N3 (RNA5-8SN3) [3]
HGNC ID HGNC:53525
Ensembl ID ENSG00000275215
Method RNA-seq GSE150239
Condition knock down
Evidence logFC: -1.162548367; p-value: 0.001266259
Cell Line 253Jcells Bladder cancer Homo sapiens CVCL_7935
Click to Download All Target Gene of This Genetic Class
Small nuclear RNA
In total 14 target gene(s)
RNA, U11 small nuclear (RNU11) [1]
HGNC ID HGNC:10108
Ensembl ID ENSG00000274978
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
RNA, U12 small nuclear (RNU12) [1]
HGNC ID HGNC:19380
Ensembl ID ENSG00000276027
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
RNA, U4 small nuclear 1 (RNU4-1) [1]
HGNC ID HGNC:10192
Ensembl ID ENSG00000200795
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
RNA, U5A small nuclear 1 (RNU5A-1) [1]
HGNC ID HGNC:10211
Ensembl ID ENSG00000199568
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
RNA, U5B small nuclear 1 (RNU5B-1) [1]
HGNC ID HGNC:10212
Ensembl ID ENSG00000200156
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
RNA, U5D small nuclear 1 (RNU5D-1) [1]
HGNC ID HGNC:10214
Ensembl ID ENSG00000200169
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
RNA, variant U1 small nuclear 1 (RNVU1-1) [1]
HGNC ID HGNC:10133
Ensembl ID ENSG00000207340
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
RNA, U4 small nuclear 2 (RNU4-2) [1]
HGNC ID HGNC:10193
Ensembl ID ENSG00000202538
Method RNA-seq GSE79577
Condition knock out
Evidence logFC: -0.698702438; p-value: 0.022611456
Cell Line HEK293 cell line Healthy Homo sapiens CVCL_0045
RNA, U5E small nuclear 1 (RNU5E-1) [1]
HGNC ID HGNC:10215
Ensembl ID ENSG00000199347
Method RNA-seq GSE79577
Condition knock out
Evidence logFC: -0.99886101; p-value: 0.004858413
Cell Line HEK293 cell line Healthy Homo sapiens CVCL_0045
RNA, U5F small nuclear 1 (RNU5F-1) [1]
HGNC ID HGNC:10216
Ensembl ID ENSG00000199377
Method RNA-seq GSE79577
Condition knock out
Evidence logFC: 0.936663497; p-value: 0.00159923
Cell Line HEK293 cell line Healthy Homo sapiens CVCL_0045
Click to Download All Target Gene of This Genetic Class
Small nucleolar RNA
In total 71 target gene(s)
Small Cajal body-specific RNA 10 (SCARNA10) [1]
HGNC ID HGNC:32567
Ensembl ID ENSG00000239002
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Small Cajal body-specific RNA 2 (SCARNA2) [1]
HGNC ID HGNC:32558
Ensembl ID ENSG00000278249
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Small nucleolar RNA, C/D box 101 (SNORD101) [1]
HGNC ID HGNC:32764
Ensembl ID ENSG00000206754
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Small nucleolar RNA, C/D box 105 (SNORD105) [1]
HGNC ID HGNC:32769
Ensembl ID ENSG00000209645
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Small nucleolar RNA, C/D box 16 (SNORD16) [1]
HGNC ID HGNC:32712
Ensembl ID ENSG00000199673
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Small nucleolar RNA, C/D box 1B (SNORD1B) [1]
HGNC ID HGNC:32676
Ensembl ID ENSG00000199961
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Small nucleolar RNA, C/D box 25 (SNORD25) [1]
HGNC ID HGNC:10147
Ensembl ID ENSG00000275043
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Small nucleolar RNA, C/D box 26 (SNORD26) [1]
HGNC ID HGNC:10148
Ensembl ID ENSG00000276788
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Small nucleolar RNA, C/D box 27 (SNORD27) [1]
HGNC ID HGNC:10149
Ensembl ID ENSG00000275996
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Small nucleolar RNA, C/D box 37 (SNORD37) [1]
HGNC ID HGNC:10166
Ensembl ID ENSG00000206775
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
Click to Download All Target Gene of This Genetic Class
Vault RNA
In total 2 target gene(s)
Vault RNA 1-1 (VTRNA1-1) [1]
HGNC ID HGNC:12654
Ensembl ID ENSG00000199990
Method RNA-seq GSE79577
Condition knock out
Evidence logFC: 0.714958825; p-value: 0.000679122
Cell Line HEK293 cell line Healthy Homo sapiens CVCL_0045
Vault RNA 1-2 (VTRNA1-2) [3]
HGNC ID HGNC:12655
Ensembl ID ENSG00000202111
Method RNA-seq GSE150239
Condition knock down
Evidence logFC: -1.063018842; p-value: 0.015345286
Cell Line 253Jcells Bladder cancer Homo sapiens CVCL_7935
Click to Download All Target Gene of This Genetic Class
Other
Complex locus constituent
In total 3 target gene(s)
Protocadherin alpha 10 (PCDHA10) [1]
HGNC ID HGNC:8664
Ensembl ID ENSG00000250120
Uniprot ID PCDAA_HUMAN
Method RNA-seq GSE79577
Condition knock out
Evidence logFC: -1.045228221; p-value: 0.004408466
Cell Line HEK293 cell line Healthy Homo sapiens CVCL_0045
Protocadherin alpha 11 (PCDHA11) [1]
HGNC ID HGNC:8665
Ensembl ID ENSG00000249158
Uniprot ID PCDAB_HUMAN
Method RNA-seq GSE79577
Condition knock out
Evidence logFC: -0.867915444; p-value: 0.001373184
Cell Line HEK293 cell line Healthy Homo sapiens CVCL_0045
Protocadherin alpha 13 (PCDHA13) [1]
HGNC ID HGNC:8667
Ensembl ID ENSG00000239389
Uniprot ID PCDAD_HUMAN
Method RNA-seq GSE79577
Condition knock out
Evidence logFC: -0.898553146; p-value: 0.00779347
Cell Line HEK293 cell line Healthy Homo sapiens CVCL_0045
Click to Download All Target Gene of This Genetic Class
Immunoglobulin gene
In total 3 target gene(s)
Immunoglobulin heavy constant alpha 1 (IGHA1) [6]
HGNC ID HGNC:5478
Ensembl ID ENSG00000211895
Uniprot ID IGHA1_HUMAN
Method RNA-seq GSE199206
Condition over expression
Evidence logFC: 6.204674331; p-value: 0.001511227
Cell Line TPC-1 Papillary thyroid cancer Homo sapiens CVCL_6298
Immunoglobulin heavy constant epsilon (IGHE) [3]
HGNC ID HGNC:5522
Ensembl ID ENSG00000211891
Uniprot ID IGHE_HUMAN
Method RNA-seq GSE150239
Condition knock down
Evidence logFC: 2.640402659; p-value: 0.040739711
Cell Line 253Jcells Bladder cancer Homo sapiens CVCL_7935
Immunoglobulin heavy variable 1/OR15-1 (non-functional) (IGHV1OR15-1) [2]
HGNC ID HGNC:5563
Ensembl ID ENSG00000270505
Method RNA-seq GSE103494
Condition knock down
Evidence logFC: -1.34139278; p-value: 0.025030449
Cell Line NB4 Acute myeloid leukemia Homo sapiens CVCL_0005
Click to Download All Target Gene of This Genetic Class
Protocadherin
In total 6 target gene(s)
Protocadherin beta 16 (PCDHB16) [3]
HGNC ID HGNC:14546
Ensembl ID ENSG00000272674
Uniprot ID PCDBG_HUMAN
Method RNA-seq GSE150239
Condition knock down
Evidence logFC: -0.784640424; p-value: 0.0055259
Cell Line 253Jcells Bladder cancer Homo sapiens CVCL_7935
Protocadherin beta 5 (PCDHB5) [3]
HGNC ID HGNC:8690
Ensembl ID ENSG00000113209
Uniprot ID PCDB5_HUMAN
Method RNA-seq GSE150239
Condition knock down
Evidence logFC: -0.904471115; p-value: 0.005110425
Cell Line 253Jcells Bladder cancer Homo sapiens CVCL_7935
Protocadherin beta 6 (PCDHB6) [3]
HGNC ID HGNC:8691
Ensembl ID ENSG00000113211
Uniprot ID PCDB6_HUMAN
Method RNA-seq GSE150239
Condition knock down
Evidence logFC: -1.101828992; p-value: 0.006904988
Cell Line 253Jcells Bladder cancer Homo sapiens CVCL_7935
Protocadherin beta 7 (PCDHB7) [3]
HGNC ID HGNC:8692
Ensembl ID ENSG00000113212
Uniprot ID PCDB7_HUMAN
Method RNA-seq GSE150239
Condition knock down
Evidence logFC: -0.973047183; p-value: 0.012237868
Cell Line 253Jcells Bladder cancer Homo sapiens CVCL_7935
Protocadherin gamma subfamily C, 3 (PCDHGC3) [2]
HGNC ID HGNC:8716
Ensembl ID ENSG00000240184
Uniprot ID PCDGK_HUMAN
Method RNA-seq GSE103494
Condition knock down
Evidence logFC: -0.727852023; p-value: 0.01817307
Cell Line NB4 Acute myeloid leukemia Homo sapiens CVCL_0005
Protocadherin gamma subfamily C, 5 (PCDHGC5) [3]
HGNC ID HGNC:8718
Ensembl ID ENSG00000240764
Uniprot ID PCDGM_HUMAN
Method RNA-seq GSE150239
Condition knock down
Evidence logFC: -0.634133151; p-value: 0.021270233
Cell Line 253Jcells Bladder cancer Homo sapiens CVCL_7935
Click to Download All Target Gene of This Genetic Class
Readthrough
In total 11 target gene(s)
ZNF670-ZNF695 readthrough (NMD candidate) (ZNF670-ZNF695) [1]
HGNC ID HGNC:49200
Ensembl ID ENSG00000135747
Method CLIP-seq GSE79577
Cell Line HEK293 Normal Homo sapiens CVCL_0045
BLOC1S5-TXNDC5 readthrough (NMD candidate) (BLOC1S5-TXNDC5) [5]
HGNC ID HGNC:42001
Ensembl ID ENSG00000259040
Method RNA-seq GSE78040
Condition knock down
Evidence logFC: 0.984195713; p-value: 2.34E-26
Cell Line HEK293T Healthy Homo sapiens CVCL_0045
DNAJC25-GNG10 readthrough (DNAJC25-GNG10) [2]
HGNC ID HGNC:37501
Ensembl ID ENSG00000244115
Method RNA-seq GSE103494
Condition knock down
Evidence logFC: -0.626221582; p-value: 0.008894775
Cell Line NB4 Acute myeloid leukemia Homo sapiens CVCL_0005
FXYD6-FXYD2 readthrough (FXYD6-FXYD2) [6]
HGNC ID HGNC:39978
Ensembl ID ENSG00000255245
Method RNA-seq GSE199206
Condition over expression
Evidence logFC: 2.424911906; p-value: 3.41E-06
Cell Line TPC-1 Papillary thyroid cancer Homo sapiens CVCL_6298
GIMAP1-GIMAP5 readthrough (GIMAP1-GIMAP5) [6]
HGNC ID HGNC:51257
Ensembl ID ENSG00000281887
Method RNA-seq GSE199206
Condition over expression
Evidence logFC: -0.684913553; p-value: 0.018785252
Cell Line TPC-1 Papillary thyroid cancer Homo sapiens CVCL_6298
LY75-CD302 readthrough (LY75-CD302) [2]
HGNC ID HGNC:38828
Ensembl ID ENSG00000248672
Method RNA-seq GSE103494
Condition knock down
Evidence logFC: 0.708065969; p-value: 0.005362188
Cell Line NB4 Acute myeloid leukemia Homo sapiens CVCL_0005
MIA-RAB4B readthrough (NMD candidate) (MIA-RAB4B) [5]
HGNC ID HGNC:48352
Ensembl ID ENSG00000268975
Method RNA-seq GSE78040
Condition knock down
Evidence logFC: -0.918334555; p-value: 0.028994832
Cell Line HEK293T Healthy Homo sapiens CVCL_0045
RBAK-RBAKDN readthrough (RBAK-RBAKDN) [5]
HGNC ID HGNC:42971
Ensembl ID ENSG00000272968
Method RNA-seq GSE78040
Condition knock down
Evidence logFC: -1.173317993; p-value: 0.000238263
Cell Line HEK293T Healthy Homo sapiens CVCL_0045
RPL17-C18orf32 readthrough (RPL17-C18orf32) [2]
HGNC ID HGNC:44661
Ensembl ID ENSG00000215472
Method RNA-seq GSE103494
Condition knock down
Evidence logFC: -0.849240722; p-value: 0.004481466
Cell Line NB4 Acute myeloid leukemia Homo sapiens CVCL_0005
RTEL1-TNFRSF6B readthrough (NMD candidate) (RTEL1-TNFRSF6B) [2]
HGNC ID HGNC:44095
Ensembl ID ENSG00000026036
Method RNA-seq GSE103494
Condition knock down
Evidence logFC: 1.033110074; p-value: 0.03077297
Cell Line NB4 Acute myeloid leukemia Homo sapiens CVCL_0005
Click to Download All Target Gene of This Genetic Class
T cell receptor gene
In total 1 target gene(s)
T cell receptor alpha constant (TRAC) [3]
HGNC ID HGNC:12029
Ensembl ID ENSG00000277734
Uniprot ID TRAC_HUMAN
Method RNA-seq GSE150239
Condition knock down
Evidence logFC: 0.606014199; p-value: 0.039453037
Cell Line 253Jcells Bladder cancer Homo sapiens CVCL_7935
Click to Download All Target Gene of This Genetic Class
Unknown
In total 3 target gene(s)
Chromosome 19 putative open reading frame 48 (C19orf48) [2]
HGNC ID HGNC:29667
Ensembl ID ENSG00000167747
Uniprot ID CS048_HUMAN
Method RNA-seq GSE103494
Condition knock down
Evidence logFC: -0.99196787; p-value: 0.023513606
Cell Line NB4 Acute myeloid leukemia Homo sapiens CVCL_0005
NBPF member 8 (NBPF8) [3]
HGNC ID HGNC:31990
Ensembl ID ENSG00000270231
Uniprot ID NBPF8_HUMAN
Method RNA-seq GSE150239
Condition knock down
Evidence logFC: 1.015302948; p-value: 0.00103957
Cell Line 253Jcells Bladder cancer Homo sapiens CVCL_7935
Nuclear factor, erythroid 4 (NFE4) [3]
HGNC ID HGNC:29902
Ensembl ID ENSG00000230257
Uniprot ID NFE4_HUMAN
Method RNA-seq GSE150239
Condition knock down
Evidence logFC: -1.142978402; p-value: 2.18E-05
Cell Line 253Jcells Bladder cancer Homo sapiens CVCL_7935
Click to Download All Target Gene of This Genetic Class
References
Ref 1 N6-methyladenosine demethylase FTO targets pre-mRNAs and regulates alternative splicing and 3'-end processing. Nucleic Acids Res. 2017 Nov 2;45(19):11356-11370. doi: 10.1093/nar/gkx778.
Ref 2 Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia. Cancer Cell. 2019 Apr 15;35(4):677-691.e10. doi: 10.1016/j.ccell.2019.03.006.
Ref 3 FTO modifies the m6A level of MALAT and promotes bladder cancer progression. Clin Transl Med. 2021 Feb;11(2):e310. doi: 10.1002/ctm2.310.
Ref 4 Next Generation Sequencing and m6A sequencing Facilitates Quantitative Analysis of Wild Type and genetic FTO knockdown ccRCC cells Transcriptomes
Ref 5 Reversible methylation of m(6)A(m) in the 5' cap controls mRNA stability. Nature. 2017 Jan 19;541(7637):371-375.
Ref 6 FTO Prevents Thyroid Cancer Progression by SLC7A11 m6A Methylation in a Ferroptosis-Dependent Manner. Front Endocrinol (Lausanne). 2022 Jun 3;13:857765.