m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01497)
Target Name Serine/threonine-protein kinase B-raf (BRAF)
Synonyms
EC 2.7.11.1; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1
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Gene Name Braf
Chromosomal Location 7q34
Family Protein kinase superfamily, TKL Ser/Thr protein kinase family, RAF subfamily
Function
Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway (PubMed:21441910, PubMed:29433126). Phosphorylates PFKFB2 (PubMed:36402789). May play a role in the postsynaptic responses of hippocampal neurons (PubMed:1508179).
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Gene ID 673
Uniprot ID
BRAF_HUMAN
HGNC ID
HGNC:1097
KEGG ID
hsa:673
References
Ref 1 Catalytic properties of polymorphic human cytochrome P450 1B1 variants. Carcinogenesis. 1999 Aug;20(8):1607-13. doi: 10.1093/carcin/20.8.1607.