m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01494)

Target Name	Cell division control protein 45 homolog (CDC45)
Synonyms	PORC-PI-1 Click to Show/Hide
Gene Name	CDC45
Chromosomal Location	22q11.21
Family	CDC45 family
Function	Required for initiation of chromosomal DNA replication. Core component of CDC45-MCM-GINS (CMG) helicase, the molecular machine that unwinds template DNA during replication, and around which the replisome is built. Click to Show/Hide
Gene ID	8318
Uniprot ID	CDC45_HUMAN
HGNC ID	HGNC:1739
KEGG ID	hsa:8318

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01494)

Cell division control protein 45 homolog (CDC45)

Adenosine-to-Inosine editing (A-to-I)

In total 15 m6A sequence/site(s) in this target gene
mod ID: A2ISITE010995		Click to Show/Hide the Full List
mod site	chr22:19500335-19500336:+		[2]
Sequence	CCTATAAACTTTACAAAATTAATGAGGGCAGGGGGAGGGGA
Transcript ID List	ENST00000263201.5; ENST00000404724.7; rmsk_5247423; ENST00000407835.5; ENST00000437685.6; ENST00000428937.1
External Link	RMBase: RNA-editing_site_90779
mod ID: A2ISITE010996		Click to Show/Hide the Full List
mod site	chr22:19500530-19500531:+		[2]
Sequence	CACAACTTGAACCTTAGGAAATGCCGTTTTCCCTTTGAGAT
Transcript ID List	ENST00000407835.5; rmsk_5247423; ENST00000428937.1; ENST00000263201.5; ENST00000404724.7; ENST00000437685.6
External Link	RMBase: RNA-editing_site_90780
mod ID: A2ISITE010997		Click to Show/Hide the Full List
mod site	chr22:19500680-19500681:+		[2]
Sequence	TCCCCCTTGCCCCACCAATCAACTATCCCAATTTTCCAGCC
Transcript ID List	ENST00000437685.6; ENST00000428937.1; ENST00000404724.7; rmsk_5247423; ENST00000407835.5; ENST00000263201.5
External Link	RMBase: RNA-editing_site_90781
mod ID: A2ISITE010998		Click to Show/Hide the Full List
mod site	chr22:19500798-19500799:+		[2]
Sequence	TGGTGCCCTGCAATCATGAAACTCTTCCTCTGCTGCAAACT
Transcript ID List	ENST00000263201.5; ENST00000404724.7; rmsk_5247423; ENST00000407835.5; ENST00000437685.6; ENST00000428937.1
External Link	RMBase: RNA-editing_site_90782
mod ID: A2ISITE010999		Click to Show/Hide the Full List
mod site	chr22:19500846-19500847:+		[2]
Sequence	CTCAGTGTAACAGGTCTGTTACTGCACAGTGGACATATGGA
Transcript ID List	ENST00000263201.5; ENST00000428937.1; ENST00000437685.6; rmsk_5247423; ENST00000407835.5; ENST00000404724.7
External Link	RMBase: RNA-editing_site_90783
mod ID: A2ISITE011000		Click to Show/Hide the Full List
mod site	chr22:19500912-19500913:+		[2]
Sequence	GAGGCCGGGCGCGATGGCTCACCCCTGTAATCCCAGCACTT
Transcript ID List	ENST00000407835.5; ENST00000263201.5; ENST00000437685.6; ENST00000404724.7; rmsk_5247424; ENST00000428937.1
External Link	RMBase: RNA-editing_site_90784
mod ID: A2ISITE011001		Click to Show/Hide the Full List
mod site	chr22:19501268-19501269:+		[2]
Sequence	CTGCGGCTAGGTGCCCCTTCACTGTTCGGTGGGCAGGACCT
Transcript ID List	ENST00000404724.7; ENST00000428937.1; ENST00000263201.5; ENST00000437685.6; rmsk_5247425; ENST00000407835.5
External Link	RMBase: RNA-editing_site_90785
mod ID: A2ISITE011002		Click to Show/Hide the Full List
mod site	chr22:19501441-19501442:+		[2]
Sequence	GCATTAGAAAAGTTTTCTCCATGCAACTGGCACCCCTTTCT
Transcript ID List	ENST00000404724.7; ENST00000428937.1; ENST00000437685.6; ENST00000407835.5; ENST00000263201.5
External Link	RMBase: RNA-editing_site_90786
mod ID: A2ISITE011003		Click to Show/Hide the Full List
mod site	chr22:19501818-19501819:+		[3]
Sequence	TGACCTCCTGGGATCAAGCAATCCTACCACCTTAGCCTCCC
Transcript ID List	ENST00000437685.6; ENST00000404724.7; ENST00000407835.5; ENST00000428937.1; ENST00000263201.5
External Link	RMBase: RNA-editing_site_90787
mod ID: A2ISITE011004		Click to Show/Hide the Full List
mod site	chr22:19503830-19503831:+		[2]
Sequence	AGAGGCCACAGGACCTCCAAAGAGGCCAGCAAATCAGAGGA
Transcript ID List	ENST00000263201.5; ENST00000404724.7; ENST00000437685.6; ENST00000407835.5; ENST00000428937.1
External Link	RMBase: RNA-editing_site_90788
mod ID: A2ISITE011005		Click to Show/Hide the Full List
mod site	chr22:19504160-19504161:+		[2]
Sequence	TTGTATGCCTGCTGTGCAGTAACAGACTTGTTACACTGAGA
Transcript ID List	ENST00000263201.5; ENST00000404724.7; ENST00000407835.5; ENST00000437685.6; ENST00000428937.1
External Link	RMBase: RNA-editing_site_90789
mod ID: A2ISITE011006		Click to Show/Hide the Full List
mod site	chr22:19504161-19504162:+		[2]
Sequence	TGTATGCCTGCTGTGCAGTAACAGACTTGTTACACTGAGAC
Transcript ID List	ENST00000407835.5; ENST00000437685.6; ENST00000263201.5; ENST00000428937.1; ENST00000404724.7
External Link	RMBase: RNA-editing_site_90790
mod ID: A2ISITE011007		Click to Show/Hide the Full List
mod site	chr22:19504172-19504173:+		[2]
Sequence	TGTGCAGTAACAGACTTGTTACACTGAGACAGCAGAGTTTG
Transcript ID List	ENST00000407835.5; ENST00000437685.6; ENST00000428937.1; ENST00000404724.7; ENST00000263201.5
External Link	RMBase: RNA-editing_site_90791
mod ID: A2ISITE011008		Click to Show/Hide the Full List
mod site	chr22:19504185-19504186:+		[2]
Sequence	ACTTGTTACACTGAGACAGCAGAGTTTGCAGCAGAGGAAGA
Transcript ID List	ENST00000407835.5; ENST00000404724.7; ENST00000437685.6; ENST00000428937.1; ENST00000263201.5
External Link	RMBase: RNA-editing_site_90792
mod ID: A2ISITE011009		Click to Show/Hide the Full List
mod site	chr22:19504197-19504198:+		[2]
Sequence	GAGACAGCAGAGTTTGCAGCAGAGGAAGAGTTTCATGATTG
Transcript ID List	ENST00000263201.5; ENST00000404724.7; ENST00000437685.6; ENST00000428937.1; ENST00000407835.5
External Link	RMBase: RNA-editing_site_90793

5-methylcytidine (m5C)

In total 6 m6A sequence/site(s) in this target gene
mod ID: M5CSITE002859		Click to Show/Hide the Full List
mod site	chr22:19504193-19504194:+
Sequence	CACTGAGACAGCAGAGTTTGCAGCAGAGGAAGAGTTTCATG
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000437685.6; ENST00000407835.5; ENST00000428937.1; ENST00000404724.7; ENST00000263201.5
External Link	RMBase: m5C_site_30323
mod ID: M5CSITE002860		Click to Show/Hide the Full List
mod site	chr22:19504196-19504197:+
Sequence	TGAGACAGCAGAGTTTGCAGCAGAGGAAGAGTTTCATGATT
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000263201.5; ENST00000437685.6; ENST00000404724.7; ENST00000428937.1; ENST00000407835.5
External Link	RMBase: m5C_site_30324
mod ID: M5CSITE002861		Click to Show/Hide the Full List
mod site	chr22:19504210-19504211:+
Sequence	TTGCAGCAGAGGAAGAGTTTCATGATTGCAGGGCACCGAGT
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000428937.1; ENST00000437685.6; ENST00000263201.5; ENST00000407835.5; ENST00000404724.7
External Link	RMBase: m5C_site_30325
mod ID: M5CSITE002862		Click to Show/Hide the Full List
mod site	chr22:19504218-19504219:+
Sequence	GAGGAAGAGTTTCATGATTGCAGGGCACCGAGTGAGAAGAT
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000437685.6; ENST00000428937.1; ENST00000407835.5; ENST00000404724.7; ENST00000263201.5
External Link	RMBase: m5C_site_30326
mod ID: M5CSITE002863		Click to Show/Hide the Full List
mod site	chr22:19504922-19504923:+
Sequence	ACGAGGAAGCAGTCAGAGAGCACGCCGACCTAGTGACTGAT
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000407835.5; ENST00000428937.1; ENST00000437685.6; ENST00000263201.5; ENST00000404724.7
External Link	RMBase: m5C_site_30327
mod ID: M5CSITE002864		Click to Show/Hide the Full List
mod site	chr22:19505454-19505455:+		[4]
Sequence	GAGAACACACTCTCCGTGGACTGCACACGGATCTCCTTTGA
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000404724.7; ENST00000471470.1; ENST00000407835.5; ENST00000263201.5; ENST00000437685.6
External Link	RMBase: m5C_site_30328

N6-methyladenosine (m6A)

In total 42 m6A sequence/site(s) in this target gene
mod ID: M6ASITE056289		Click to Show/Hide the Full List
mod site	chr22:19480036-19480037:+		[5]
Sequence	CAGGTGACGCCCAGTCCGGGACCCCCGCCGAGGCCTTGCCG
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000404724.7; ENST00000263201.5; ENST00000438587.5; ENST00000437685.6; ENST00000455750.5; ENST00000407835.5; ENST00000483431.5; ENST00000491520.5
External Link	RMBase: m6A_site_554756
mod ID: M6ASITE056290		Click to Show/Hide the Full List
mod site	chr22:19482729-19482730:+		[5]
Sequence	AAACTGTGGAGCTAATGTAGACCTATTGGATATTCTTCAAC
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000455750.5; ENST00000438587.5; ENST00000263201.5; ENST00000487669.5; ENST00000437685.6; ENST00000404724.7; ENST00000407835.5; ENST00000483431.5; ENST00000491520.5
External Link	RMBase: m6A_site_554757
mod ID: M6ASITE056291		Click to Show/Hide the Full List
mod site	chr22:19482759-19482760:+		[5]
Sequence	TATTCTTCAACCTGATGAAGACACTATATTCTTTGTGTGTG
Motif Score	2.897386905
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000437685.6; ENST00000263201.5; ENST00000404724.7; ENST00000407835.5; ENST00000428937.1; ENST00000438587.5; ENST00000483431.5; ENST00000455750.5; ENST00000487669.5; ENST00000491520.5
External Link	RMBase: m6A_site_554758
mod ID: M6ASITE056292		Click to Show/Hide the Full List
mod site	chr22:19483878-19483879:+		[5]
Sequence	TAGATCAAATTACTCATTAAACAAGATGATGACCTTGAAGT
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000263201.5; ENST00000428937.1; ENST00000404724.7; ENST00000437685.6; ENST00000483431.5; ENST00000487669.5; ENST00000438587.5; ENST00000407835.5
External Link	RMBase: m6A_site_554759
mod ID: M6ASITE056293		Click to Show/Hide the Full List
mod site	chr22:19483913-19483914:+		[5]
Sequence	TGAAGTTCCCGCCTATGAAGACATCTTCAGGGATGAAGAGG
Motif Score	2.897386905
Cell/Tissue List	HeLa; hESC-HEK293T; MT4; Huh7
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000263201.5; ENST00000407835.5; ENST00000487669.5; ENST00000404724.7; ENST00000438587.5; ENST00000428937.1; ENST00000437685.6; ENST00000483431.5
External Link	RMBase: m6A_site_554760
mod ID: M6ASITE056294		Click to Show/Hide the Full List
mod site	chr22:19483990-19483991:+		[6]
Sequence	CAGAGCCTTCTGAGAAGCGCACACGGTTAGAAGAGGTGAGT
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000404724.7; ENST00000487669.5; ENST00000407835.5; ENST00000438587.5; ENST00000263201.5; ENST00000483431.5; ENST00000437685.6; ENST00000428937.1
External Link	RMBase: m6A_site_554761
mod ID: M6ASITE056295		Click to Show/Hide the Full List
mod site	chr22:19494341-19494342:+		[5]
Sequence	ATCAGGAGATAGTGGAGCAAACCATGCGGAGGAGGCAGCGG
Motif Score	2.185083333
Cell/Tissue List	HeLa; HEK293T; MT4; Huh7; Jurkat
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000438587.5; ENST00000428937.1; ENST00000263201.5; ENST00000483431.5; ENST00000487669.5; ENST00000407835.5; ENST00000437685.6; ENST00000404724.7
External Link	RMBase: m6A_site_554762
mod ID: M6ASITE056296		Click to Show/Hide the Full List
mod site	chr22:19494493-19494494:+		[5]
Sequence	GATAATTTATTGAGTTTAGAACCTTTGGGCCAGTGGCTCTG
Motif Score	2.930744048
Cell/Tissue List	HeLa; HEK293T; LCLs; MT4; Huh7; Jurkat; MM6
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000437685.6; ENST00000404724.7; ENST00000483431.5; ENST00000428937.1; ENST00000487669.5; ENST00000263201.5; ENST00000407835.5
External Link	RMBase: m6A_site_554763
mod ID: M6ASITE056297		Click to Show/Hide the Full List
mod site	chr22:19494521-19494522:+		[7]
Sequence	GCCAGTGGCTCTGGGAGTGAACCTGTGGCCGCTGCATTGGA
Motif Score	2.930744048
Cell/Tissue List	MT4; Huh7; MM6
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000407835.5; ENST00000404724.7; ENST00000487669.5; ENST00000428937.1; ENST00000263201.5; ENST00000483431.5; ENST00000437685.6
External Link	RMBase: m6A_site_554764
mod ID: M6ASITE056298		Click to Show/Hide the Full List
mod site	chr22:19494582-19494583:+		[8]
Sequence	CCGGTCCCATGAGTGACAGGACAGCCCCAAGGTCTCCCAGG
Motif Score	3.643047619
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000437685.6; ENST00000487669.5; ENST00000404724.7; ENST00000263201.5; ENST00000428937.1; ENST00000483431.5; ENST00000407835.5
External Link	RMBase: m6A_site_554765
mod ID: M6ASITE056299		Click to Show/Hide the Full List
mod site	chr22:19495985-19495986:+		[6]
Sequence	TTTATGTCATTACAGAAGAGACATCCTCTTTGACTACGAGC
Motif Score	2.897386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000404724.7; ENST00000437685.6; ENST00000428937.1; ENST00000487669.5; ENST00000407835.5; ENST00000263201.5; ENST00000483431.5
External Link	RMBase: m6A_site_554766
mod ID: M6ASITE056300		Click to Show/Hide the Full List
mod site	chr22:19496023-19496024:+		[6]
Sequence	AGCAGTATGAATATCATGGGACATCGGTAAGTATGAATAGG
Motif Score	3.643047619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000487669.5; ENST00000428937.1; ENST00000263201.5; ENST00000437685.6; ENST00000407835.5; ENST00000404724.7
External Link	RMBase: m6A_site_554767
mod ID: M6ASITE056301		Click to Show/Hide the Full List
mod site	chr22:19497428-19497429:+		[9]
Sequence	GGCTTGGATGCTGTCCAAGGACCTGAATGACATGCTGTGGT
Motif Score	3.622404762
Cell/Tissue List	HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000487669.5; ENST00000428937.1; ENST00000263201.5; ENST00000437685.6; ENST00000407835.5; ENST00000404724.7
External Link	RMBase: m6A_site_554768
mod ID: M6ASITE056302		Click to Show/Hide the Full List
mod site	chr22:19497437-19497438:+		[6]
Sequence	GCTGTCCAAGGACCTGAATGACATGCTGTGGTACGTAGCCC
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000263201.5; ENST00000437685.6; ENST00000404724.7; ENST00000487669.5; ENST00000407835.5; ENST00000428937.1
External Link	RMBase: m6A_site_554769
mod ID: M6ASITE056303		Click to Show/Hide the Full List
mod site	chr22:19499115-19499116:+		[9]
Sequence	TCCAGGTGGGCCATCGTTGGACTAACAGACCAGTGGGTGCA
Motif Score	4.065041667
Cell/Tissue List	HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000404724.7; ENST00000428937.1; ENST00000407835.5; ENST00000437685.6; ENST00000263201.5
External Link	RMBase: m6A_site_554770
mod ID: M6ASITE056304		Click to Show/Hide the Full List
mod site	chr22:19499138-19499139:+		[6]
Sequence	AACAGACCAGTGGGTGCAAGACAAGATCACTCAGTAAGGAC
Motif Score	2.897386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000428937.1; ENST00000404724.7; ENST00000263201.5; ENST00000437685.6; ENST00000407835.5
External Link	RMBase: m6A_site_554771
mod ID: M6ASITE056305		Click to Show/Hide the Full List
mod site	chr22:19505328-19505329:+		[7]
Sequence	CCTGGTAAGAGCTGGAGGGAACCAGCCGAGGCTTGTGCTAC
Motif Score	2.930744048
Cell/Tissue List	MT4
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000407835.5; ENST00000471470.1; ENST00000263201.5; ENST00000437685.6; ENST00000404724.7; ENST00000428937.1
External Link	RMBase: m6A_site_554772
mod ID: M6ASITE056306		Click to Show/Hide the Full List
mod site	chr22:19505411-19505412:+		[6]
Sequence	GCAGCGCCACGTTTCCCGCCACAACCACCGGAACGAGGATG
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000263201.5; ENST00000404724.7; ENST00000437685.6; ENST00000471470.1; ENST00000407835.5
External Link	RMBase: m6A_site_554773
mod ID: M6ASITE056307		Click to Show/Hide the Full List
mod site	chr22:19505438-19505439:+		[7]
Sequence	CCGGAACGAGGATGAGGAGAACACACTCTCCGTGGACTGCA
Motif Score	2.951386905
Cell/Tissue List	MT4
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000404724.7; ENST00000471470.1; ENST00000437685.6; ENST00000407835.5; ENST00000263201.5
External Link	RMBase: m6A_site_554774
mod ID: M6ASITE056308		Click to Show/Hide the Full List
mod site	chr22:19505453-19505454:+		[7]
Sequence	GGAGAACACACTCTCCGTGGACTGCACACGGATCTCCTTTG
Motif Score	4.065041667
Cell/Tissue List	MT4
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000471470.1; ENST00000437685.6; ENST00000404724.7; ENST00000263201.5; ENST00000407835.5
External Link	RMBase: m6A_site_554775
mod ID: M6ASITE056309		Click to Show/Hide the Full List
mod site	chr22:19505458-19505459:+		[6]
Sequence	ACACACTCTCCGTGGACTGCACACGGATCTCCTTTGAGTAT
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000471470.1; ENST00000263201.5; ENST00000437685.6; ENST00000404724.7; ENST00000407835.5
External Link	RMBase: m6A_site_554776
mod ID: M6ASITE056310		Click to Show/Hide the Full List
mod site	chr22:19507435-19507436:+		[6]
Sequence	CCTCCATGACAGCCTGTGCAACACCAGCTATACCGCAGCCA
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000471470.1; ENST00000263201.5; ENST00000437685.6; ENST00000407835.5; ENST00000404724.7
External Link	RMBase: m6A_site_554777
mod ID: M6ASITE056311		Click to Show/Hide the Full List
mod site	chr22:19507510-19507511:+		[6]
Sequence	GCTCCAGGAGTTCCTTGCAGACATGGGGTGAGTGACTGCCT
Motif Score	2.897386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000471470.1; ENST00000263201.5; ENST00000407835.5; ENST00000437685.6; ENST00000404724.7
External Link	RMBase: m6A_site_554778
mod ID: M6ASITE056312		Click to Show/Hide the Full List
mod site	chr22:19507806-19507807:+		[6]
Sequence	GCAGAAGTTCCAGGCCATGGACATCTCCTTGAAGGAGAATT
Motif Score	3.643047619
Cell/Tissue List	hESC-HEK293T; MT4
Seq Type List	MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000437685.6; ENST00000407835.5; ENST00000404724.7; ENST00000471470.1; ENST00000263201.5
External Link	RMBase: m6A_site_554779
mod ID: M6ASITE056313		Click to Show/Hide the Full List
mod site	chr22:19508537-19508538:+		[6]
Sequence	CTCCCATGACAGGATGAAGGACATGCGCGTGCAGACTTTCA
Motif Score	3.643047619
Cell/Tissue List	hESC-HEK293T; MT4
Seq Type List	MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000437685.6; ENST00000404724.7; ENST00000471470.1; ENST00000407835.5; ENST00000263201.5
External Link	RMBase: m6A_site_554780
mod ID: M6ASITE056314		Click to Show/Hide the Full List
mod site	chr22:19508551-19508552:+		[10]
Sequence	TGAAGGACATGCGCGTGCAGACTTTCAGCATTCATTTTGGG
Motif Score	3.319380952
Cell/Tissue List	HEK293T; MT4
Seq Type List	DART-seq; MeRIP-seq
Transcript ID List	ENST00000471470.1; ENST00000404724.7; ENST00000407835.5; ENST00000437685.6; ENST00000263201.5
External Link	RMBase: m6A_site_554781
mod ID: M6ASITE056315		Click to Show/Hide the Full List
mod site	chr22:19508579-19508580:+		[6]
Sequence	CATTCATTTTGGGTTCAAGCACAAGTTTCTGGCCAGCGACG
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000404724.7; ENST00000471470.1; ENST00000263201.5; ENST00000437685.6; ENST00000407835.5
External Link	RMBase: m6A_site_554782
mod ID: M6ASITE056316		Click to Show/Hide the Full List
mod site	chr22:19508653-19508654:+		[7]
Sequence	CCGAGAAGGATGGCTCAGGGACAGATCACTTCATCCAGGCT
Motif Score	3.643047619
Cell/Tissue List	MT4
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000437685.6; ENST00000471470.1; ENST00000404724.7; ENST00000263201.5; ENST00000407835.5
External Link	RMBase: m6A_site_554783
mod ID: M6ASITE056317		Click to Show/Hide the Full List
mod site	chr22:19508678-19508679:+		[7]
Sequence	TCACTTCATCCAGGCTCTGGACAGCCTCTCCAGGTAGCAGG
Motif Score	3.643047619
Cell/Tissue List	MT4
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000263201.5; ENST00000471470.1; ENST00000404724.7; ENST00000437685.6; ENST00000407835.5
External Link	RMBase: m6A_site_554784
mod ID: M6ASITE056318		Click to Show/Hide the Full List
mod site	chr22:19514759-19514760:+		[6]
Sequence	CTGTTACAGGAGTAACCTGGACAAGCTGTACCATGGCCTGG
Motif Score	3.643047619
Cell/Tissue List	hESC-HEK293T; HEC-1-A
Seq Type List	MAZTER-seq; m6A-seq
Transcript ID List	ENST00000437685.6; ENST00000404724.7; ENST00000471470.1; ENST00000407835.5; ENST00000263201.5
External Link	RMBase: m6A_site_554785
mod ID: M6ASITE056319		Click to Show/Hide the Full List
mod site	chr22:19514781-19514782:+		[11]
Sequence	AAGCTGTACCATGGCCTGGAACTCGCCAAGAAGCAGCTGCG
Motif Score	3.373380952
Cell/Tissue List	HEK293T; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000407835.5; ENST00000437685.6; ENST00000471470.1; ENST00000404724.7; ENST00000263201.5
External Link	RMBase: m6A_site_554786
mod ID: M6ASITE056320		Click to Show/Hide the Full List
mod site	chr22:19514815-19514816:+		[11]
Sequence	AGCTGCGAGCCACCCAGCAGACCATTGCCAGCTGCCTTTGC
Motif Score	2.876744048
Cell/Tissue List	HEK293T; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000263201.5; ENST00000404724.7; ENST00000407835.5; ENST00000437685.6
External Link	RMBase: m6A_site_554787
mod ID: M6ASITE056321		Click to Show/Hide the Full List
mod site	chr22:19515020-19515021:+		[6]
Sequence	TCCCTAAGCCTGCTCAGCAAACACCTGCTCAAGTCCTTTGT
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000404724.7; ENST00000437685.6; ENST00000263201.5; ENST00000407835.5
External Link	RMBase: m6A_site_554788
mod ID: M6ASITE056322		Click to Show/Hide the Full List
mod site	chr22:19516526-19516527:+		[6]
Sequence	GGTGCTCTCCGACTCCATAGACAAAGAACCGGCGCTGCAAA
Motif Score	2.897386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000404724.7; ENST00000263201.5; ENST00000437685.6; ENST00000493724.1; ENST00000407835.5
External Link	RMBase: m6A_site_554789
mod ID: M6ASITE056323		Click to Show/Hide the Full List
mod site	chr22:19516533-19516534:+		[12]
Sequence	TCCGACTCCATAGACAAAGAACCGGCGCTGCAAACTGCTGC
Motif Score	2.930744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000437685.6; ENST00000493724.1; ENST00000404724.7; ENST00000263201.5; ENST00000407835.5
External Link	RMBase: m6A_site_554790
mod ID: M6ASITE056324		Click to Show/Hide the Full List
mod site	chr22:19516546-19516547:+		[12]
Sequence	ACAAAGAACCGGCGCTGCAAACTGCTGCCCCTGGTGATGGC
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000263201.5; ENST00000404724.7; ENST00000493724.1; ENST00000437685.6; ENST00000407835.5
External Link	RMBase: m6A_site_554791
mod ID: M6ASITE056325		Click to Show/Hide the Full List
mod site	chr22:19516622-19516623:+		[13]
Sequence	TGGTGGGCATCCCCCCAGAGACCGACAGCTCGGACAGGAAG
Motif Score	2.876744048
Cell/Tissue List	HepG2; HeLa; peripheral-blood; endometrial; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000404724.7; ENST00000263201.5; ENST00000437685.6; ENST00000493724.1; ENST00000407835.5
External Link	RMBase: m6A_site_554792
mod ID: M6ASITE056326		Click to Show/Hide the Full List
mod site	chr22:19516635-19516636:+		[13]
Sequence	CCCAGAGACCGACAGCTCGGACAGGAAGAAGTGAGCAGCTT
Motif Score	3.643047619
Cell/Tissue List	HepG2; HeLa; HEK293; peripheral-blood; endometrial; HEC-1-A
Seq Type List	m6A-seq; m6A-REF-seq
Transcript ID List	ENST00000493724.1; ENST00000263201.5; ENST00000407835.5; ENST00000404724.7; ENST00000437685.6
External Link	RMBase: m6A_site_554793
mod ID: M6ASITE056327		Click to Show/Hide the Full List
mod site	chr22:19516853-19516854:+		[10]
Sequence	TTGAGAAGGCAGCGGAAAGCACCAGCTCCCGGATGCTGCAC
Motif Score	2.809946429
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000407835.5; ENST00000493724.1; ENST00000404724.7; ENST00000263201.5; ENST00000437685.6
External Link	RMBase: m6A_site_554794
mod ID: M6ASITE056328		Click to Show/Hide the Full List
mod site	chr22:19516872-19516873:+		[6]
Sequence	CACCAGCTCCCGGATGCTGCACAACCATTTTGACCTCTCAG
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000407835.5; ENST00000263201.5; ENST00000404724.7; ENST00000493724.1; ENST00000437685.6
External Link	RMBase: m6A_site_554795
mod ID: M6ASITE056329		Click to Show/Hide the Full List
mod site	chr22:19520517-19520518:+		[10]
Sequence	ATGACCTTCTTATTTATGTAACTGGCTTTCATTTAGATTGT
Motif Score	2.590089286
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000437685.6; ENST00000404724.7; ENST00000407835.5; ENST00000493724.1; ENST00000263201.5
External Link	RMBase: m6A_site_554796
mod ID: M6ASITE056330		Click to Show/Hide the Full List
mod site	chr22:19520547-19520548:+		[10]
Sequence	ATTTAGATTGTAAGTTATGGACATGATTTGAGATGTAGAAG
Motif Score	3.643047619
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000263201.5; ENST00000407835.5; ENST00000493724.1; ENST00000404724.7; ENST00000437685.6
External Link	RMBase: m6A_site_554797

N7-methylguanosine (m7G)

In total 1 m6A sequence/site(s) in this target gene
mod ID: m7GSITE000091		Click to Show/Hide the Full List
mod site	chr22:19518868-19518869:+		[14]
Sequence	GAGCTGAAAGCTGAGGATCGGAGCAAGTTTCTGGACGCACT
Cell/Tissue List	A549; HeLa; HepG2
Seq Type List	BoRed-seq&m7G-RIP-seq; m7G-seq
Transcript ID List	ENST00000437685.6; ENST00000263201.5; ENST00000404724.7; ENST00000407835.5; ENST00000493724.1
External Link	RMBase: m7G_site_604

Pseudouridine (Pseudo)

In total 1 m6A sequence/site(s) in this target gene
mod ID: PSESITE000173		Click to Show/Hide the Full List
mod site	chr22:19508567-19508568:+		[15]
Sequence	GCAGACTTTCAGCATTCATTTTGGGTTCAAGCACAAGTTTC
Transcript ID List	ENST00000407835.5; ENST00000471470.1; ENST00000404724.7; ENST00000437685.6; ENST00000263201.5
External Link	RMBase: Pseudo_site_3395

Ref 1	Mechanism-based inactivation of cytochrome P450 3A4 by lapatinib. Mol Pharmacol. 2010 Oct;78(4):693-703. doi: 10.1124/mol.110.065839. Epub 2010 Jul 12.
Ref 2	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 3	Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome. Nat Biotechnol. 2012 Feb 12;30(3):253-60. doi: 10.1038/nbt.2122.
Ref 4	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 5	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 6	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 7	Dynamics of the human and viral m(6)A RNA methylomes during HIV-1 infection of T cells. Nat Microbiol. 2016 Feb 22;1:16011. doi: 10.1038/nmicrobiol.2016.11.
Ref 8	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.
Ref 9	Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq. Nature. 2012 Apr 29;485(7397):201-6. doi: 10.1038/nature11112.
Ref 10	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 11	Dynamics of Human and Viral RNA Methylation during Zika Virus Infection. Cell Host Microbe. 2016 Nov 9;20(5):666-673. doi: 10.1016/j.chom.2016.10.002. Epub 2016 Oct 20.
Ref 12	RNA m(6)A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail. Nat Commun. 2019 May 6;10(1):2065. doi: 10.1038/s41467-019-09865-9.
Ref 13	Histone H3 trimethylation at lysine 36 guides m(6)A RNA modification co-transcriptionally. Nature. 2019 Mar;567(7748):414-419. doi: 10.1038/s41586-019-1016-7. Epub 2019 Mar 13.
Ref 14	METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation. Mol Cell. 2019 Jun 20;74(6):1278-1290.e9. doi: 10.1016/j.molcel.2019.03.040. Epub 2019 Apr 25.
Ref 15	Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome. Nat Chem Biol. 2015 Aug;11(8):592-7. doi: 10.1038/nchembio.1836. Epub 2015 Jun 15.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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