m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01473)

Target Name	Placenta-specific gene 8 protein (PLAC8)
Synonyms	Protein C15 Click to Show/Hide
Gene Name	PLAC8
Chromosomal Location	4q21.22
Family	Cornifelin family
Gene ID	51316
Uniprot ID	PLAC8_HUMAN
HGNC ID	HGNC:19254
KEGG ID	hsa:51316

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01473)

Placenta-specific gene 8 protein (PLAC8)

Adenosine-to-Inosine editing (A-to-I)

In total 2 m6A sequence/site(s) in this target gene
mod ID: A2ISITE000437		Click to Show/Hide the Full List
mod site	chr4:83111195-83111196:-		[2]
Sequence	CAGGAAGATCACTTGAGGCCAGGAGCTCAAGGTCAGCCTGG
Transcript ID List	ENST00000509973.5; ENST00000515389.5; ENST00000426923.2; rmsk_1362388; ENST00000505406.5; ENST00000311507.8
External Link	RMBase: RNA-editing_site_105560
mod ID: A2ISITE000438		Click to Show/Hide the Full List
mod site	chr4:83112147-83112148:-		[3]
Sequence	GGAGTCTCGCTCTGTCATCCAGGCTGGAATGCAATGGCACG
Transcript ID List	ENST00000311507.8; ENST00000509973.5; ENST00000505406.5; ENST00000515389.5; ENST00000426923.2
External Link	RMBase: RNA-editing_site_105561

N6-methyladenosine (m6A)

In total 4 m6A sequence/site(s) in this target gene
mod ID: M6ASITE066326		Click to Show/Hide the Full List
mod site	chr4:83090870-83090871:-		[4]
Sequence	TATGATGGATATGCTTAAGTACAACTGATGGCATGAAAAAA
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000411416.6; ENST00000515389.5; ENST00000509973.5; ENST00000505406.5; ENST00000311507.8
External Link	RMBase: m6A_site_642757
mod ID: M6ASITE066327		Click to Show/Hide the Full List
mod site	chr4:83090934-83090935:-		[4]
Sequence	GAAGCAACAAAATTCAGCAGACACCTCTTCAGCTTGAGTTC
Motif Score	2.897386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000411416.6; ENST00000509973.5; ENST00000515389.5; ENST00000311507.8; ENST00000505406.5
External Link	RMBase: m6A_site_642758
mod ID: M6ASITE066328		Click to Show/Hide the Full List
mod site	chr4:83107839-83107840:-		[5]
Sequence	CCCAGAACTCCAACTGGCAGACAGGCATGTGTGACTGTTTC
Motif Score	2.897386905
Cell/Tissue List	iSLK
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000311507.8; ENST00000426923.2; ENST00000411416.6; ENST00000509973.5; ENST00000515389.5; ENST00000505406.5
External Link	RMBase: m6A_site_642759
mod ID: M6ASITE066330		Click to Show/Hide the Full List
mod site	chr4:83107853-83107854:-		[5]
Sequence	TCCCGGTCCGGCCCCCCAGAACTCCAACTGGCAGACAGGCA
Motif Score	3.373380952
Cell/Tissue List	iSLK
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000509973.5; ENST00000411416.6; ENST00000515389.5; ENST00000426923.2; ENST00000311507.8; ENST00000505406.5
External Link	RMBase: m6A_site_642760

Ref 1	Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitors. Nat Rev Drug Discov. 2005 May;4(5):421-40. doi: 10.1038/nrd1718.
Ref 2	Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome. Nat Biotechnol. 2012 Feb 12;30(3):253-60. doi: 10.1038/nbt.2122.
Ref 3	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 4	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 5	Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018 Jan;3(1):108-120. doi: 10.1038/s41564-017-0056-8. Epub 2017 Nov 6.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

Visitor Map