m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01470)

Target Name	Ras-related protein R-Ras (RRAS)
Synonyms	EC 3.6.5.-; p23 Click to Show/Hide
Gene Name	RRAS
Chromosomal Location	19q13.33
Family	Small GTPase superfamily, Ras family
Function	Regulates the organization of the actin cytoskeleton (PubMed:16537651, PubMed:18270267). With OSPBL3, modulates integrin beta-1 (ITGB1) activity (PubMed:18270267). Click to Show/Hide
Gene ID	6237
Uniprot ID	RRAS_HUMAN
HGNC ID	HGNC:10447
KEGG ID	hsa:6237

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01470)

Ras-related protein R-Ras (RRAS)

5-methylcytidine (m5C)

In total 16 m6A sequence/site(s) in this target gene
mod ID: M5CSITE002091		Click to Show/Hide the Full List
mod site	chr19:49640020-49640021:-		[2]
Sequence	GGGCCCGGGGACCCCCCGCCCAGCGAGACACACAAGCTGGT
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m5C_site_25242
mod ID: M5CSITE002092		Click to Show/Hide the Full List
mod site	chr19:49640021-49640022:-		[2]
Sequence	TGGGCCCGGGGACCCCCCGCCCAGCGAGACACACAAGCTGG
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m5C_site_25243
mod ID: M5CSITE002093		Click to Show/Hide the Full List
mod site	chr19:49640022-49640023:-		[2]
Sequence	CTGGGCCCGGGGACCCCCCGCCCAGCGAGACACACAAGCTG
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m5C_site_25244
mod ID: M5CSITE002094		Click to Show/Hide the Full List
mod site	chr19:49640024-49640025:-		[2]
Sequence	ACCTGGGCCCGGGGACCCCCCGCCCAGCGAGACACACAAGC
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m5C_site_25245
mod ID: M5CSITE002095		Click to Show/Hide the Full List
mod site	chr19:49640025-49640026:-		[2]
Sequence	GACCTGGGCCCGGGGACCCCCCGCCCAGCGAGACACACAAG
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m5C_site_25246
mod ID: M5CSITE002096		Click to Show/Hide the Full List
mod site	chr19:49640026-49640027:-		[2]
Sequence	GGACCTGGGCCCGGGGACCCCCCGCCCAGCGAGACACACAA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000601532.1; ENST00000246792.4
External Link	RMBase: m5C_site_25247
mod ID: M5CSITE002097		Click to Show/Hide the Full List
mod site	chr19:49640027-49640028:-		[2]
Sequence	GGGACCTGGGCCCGGGGACCCCCCGCCCAGCGAGACACACA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000601532.1; ENST00000246792.4
External Link	RMBase: m5C_site_25248
mod ID: M5CSITE002098		Click to Show/Hide the Full List
mod site	chr19:49640028-49640029:-		[2]
Sequence	GGGGACCTGGGCCCGGGGACCCCCCGCCCAGCGAGACACAC
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m5C_site_25249
mod ID: M5CSITE002099		Click to Show/Hide the Full List
mod site	chr19:49640029-49640030:-		[2]
Sequence	GGGGGACCTGGGCCCGGGGACCCCCCGCCCAGCGAGACACA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000601532.1; ENST00000246792.4
External Link	RMBase: m5C_site_25250
mod ID: M5CSITE002100		Click to Show/Hide the Full List
mod site	chr19:49640035-49640036:-
Sequence	CGGGGCGGGGGACCTGGGCCCGGGGACCCCCCGCCCAGCGA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m5C_site_25251
mod ID: M5CSITE002101		Click to Show/Hide the Full List
mod site	chr19:49640036-49640037:-
Sequence	CCGGGGCGGGGGACCTGGGCCCGGGGACCCCCCGCCCAGCG
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m5C_site_25252
mod ID: M5CSITE002102		Click to Show/Hide the Full List
mod site	chr19:49640055-49640056:-
Sequence	GGACAGGGCGGGGGCGGCCCCGGGGCGGGGGACCTGGGCCC
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m5C_site_25253
mod ID: M5CSITE002103		Click to Show/Hide the Full List
mod site	chr19:49640056-49640057:-
Sequence	GGGACAGGGCGGGGGCGGCCCCGGGGCGGGGGACCTGGGCC
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m5C_site_25254
mod ID: M5CSITE002104		Click to Show/Hide the Full List
mod site	chr19:49640057-49640058:-
Sequence	CGGGACAGGGCGGGGGCGGCCCCGGGGCGGGGGACCTGGGC
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000601532.1; ENST00000246792.4
External Link	RMBase: m5C_site_25255
mod ID: M5CSITE002105		Click to Show/Hide the Full List
mod site	chr19:49640058-49640059:-
Sequence	CCGGGACAGGGCGGGGGCGGCCCCGGGGCGGGGGACCTGGG
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m5C_site_25256
mod ID: M5CSITE002106		Click to Show/Hide the Full List
mod site	chr19:49640067-49640068:-
Sequence	GGGCGGCGTCCGGGACAGGGCGGGGGCGGCCCCGGGGCGGG
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m5C_site_25257

N6-methyladenosine (m6A)

In total 19 m6A sequence/site(s) in this target gene
mod ID: M6ASITE042027		Click to Show/Hide the Full List
mod site	chr19:49635439-49635440:-		[3]
Sequence	CACATCACATACCCACCCTTACTTCCTGGCCTCTTCTGGGC
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000246792.4
External Link	RMBase: m6A_site_448826
mod ID: M6ASITE042028		Click to Show/Hide the Full List
mod site	chr19:49635460-49635461:-		[4]
Sequence	CCTCATCTGGGTCTCCCAGGACACATCACATACCCACCCTT
Motif Score	3.643047619
Cell/Tissue List	HeLa; hESC-HEK293T; A549; Huh7; TREX; HEC-1-A
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000246792.4
External Link	RMBase: m6A_site_448827
mod ID: M6ASITE042029		Click to Show/Hide the Full List
mod site	chr19:49635536-49635537:-		[4]
Sequence	AACCACCACAAGCTCTCGGGACTAGCTGCCTTCGCACCTTG
Motif Score	4.065041667
Cell/Tissue List	HeLa; A549; MM6; Huh7; HEK293T; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000246792.4
External Link	RMBase: m6A_site_448828
mod ID: M6ASITE042030		Click to Show/Hide the Full List
mod site	chr19:49635549-49635550:-		[5]
Sequence	GCAAGAGAGAAGCAACCACCACAAGCTCTCGGGACTAGCTG
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000246792.4
External Link	RMBase: m6A_site_448829
mod ID: M6ASITE042031		Click to Show/Hide the Full List
mod site	chr19:49635647-49635648:-		[4]
Sequence	TCCCACAGGAAATACCAGGAACAAGAGCTCCCACCGAGCCC
Motif Score	2.951386905
Cell/Tissue List	HeLa; hESC-HEK293T; MM6; Huh7; endometrial; HEC-1-A
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000246792.4
External Link	RMBase: m6A_site_448830
mod ID: M6ASITE042032		Click to Show/Hide the Full List
mod site	chr19:49635783-49635784:-		[4]
Sequence	TACTTTGAGGCCTCGGCCAAACTGCGTCTCAACGTGGACGA
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; HEK293T; endometrial; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000246792.4
External Link	RMBase: m6A_site_448831
mod ID: M6ASITE042033		Click to Show/Hide the Full List
mod site	chr19:49636627-49636628:-		[6]
Sequence	AACAAGGCAGATCTGGAGTCACAGCGCCAGGTTCGGGACAC
Motif Score	2.047297619
Cell/Tissue List	kidney
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m6A_site_448832
mod ID: M6ASITE042034		Click to Show/Hide the Full List
mod site	chr19:49636646-49636647:-		[4]
Sequence	CCCCGTTGTGTTGGTCGGGAACAAGGCAGATCTGGAGTCAC
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; peripheral-blood; HEK293T; endometrial; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000601532.1; ENST00000246792.4
External Link	RMBase: m6A_site_448833
mod ID: M6ASITE042035		Click to Show/Hide the Full List
mod site	chr19:49636679-49636680:-		[4]
Sequence	GCAGATTCTGCGGGTCAAGGACCGCGACGACTTCCCCGTTG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; peripheral-blood; HEK293T; endometrial; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000601532.1; ENST00000246792.4
External Link	RMBase: m6A_site_448834
mod ID: M6ASITE042036		Click to Show/Hide the Full List
mod site	chr19:49636877-49636878:-		[5]
Sequence	CGGGGCCATGAGAGAGCAGTACATGCGTGCTGGCCACGGCT
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m6A_site_448835
mod ID: M6ASITE042037		Click to Show/Hide the Full List
mod site	chr19:49636919-49636920:-		[4]
Sequence	CCCTGTCTCTGCAGTCCTGGACACCGCGGGCCAGGAAGAGT
Motif Score	3.643047619
Cell/Tissue List	HeLa; A549; hESC-HEK293T; peripheral-blood; GSC-11; HEK293A-TOA; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000601532.1; ENST00000246792.4
External Link	RMBase: m6A_site_448836
mod ID: M6ASITE042038		Click to Show/Hide the Full List
mod site	chr19:49637044-49637045:-		[4]
Sequence	TGGCATCCCAGCCCGGCTGGACAGTGAGGGCGGCAAGGATG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; A549; hESC-HEK293T; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000601532.1; ENST00000246792.4
External Link	RMBase: m6A_site_448837
mod ID: M6ASITE042039		Click to Show/Hide the Full List
mod site	chr19:49637086-49637087:-		[5]
Sequence	CCCCACTATTGAGGACTCCTACACGAAGATCTGCAGTGTGG
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m6A_site_448838
mod ID: M6ASITE042040		Click to Show/Hide the Full List
mod site	chr19:49637092-49637093:-		[4]
Sequence	CTACGACCCCACTATTGAGGACTCCTACACGAAGATCTGCA
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; A549; U2OS; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; MM6
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m6A_site_448839
mod ID: M6ASITE042041		Click to Show/Hide the Full List
mod site	chr19:49640009-49640010:-		[5]
Sequence	CCCCCCGCCCAGCGAGACACACAAGCTGGTGGTCGTGGGCG
Motif Score	2.084928571
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000601532.1; ENST00000246792.4
External Link	RMBase: m6A_site_448840
mod ID: M6ASITE042042		Click to Show/Hide the Full List
mod site	chr19:49640013-49640014:-		[4]
Sequence	GGGACCCCCCGCCCAGCGAGACACACAAGCTGGTGGTCGTG
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; A549; U2OS; fibroblasts; H1299; MM6; Jurkat; CD4T; GSC-11; HEK293T; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m6A_site_448841
mod ID: M6ASITE042043		Click to Show/Hide the Full List
mod site	chr19:49640030-49640031:-		[4]
Sequence	CGGGGGACCTGGGCCCGGGGACCCCCCGCCCAGCGAGACAC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; A549; U2OS; fibroblasts; H1299; Jurkat; CD4T; GSC-11; HEK293T; HEK293A-TOA; MSC; iSLK; TIME; TREX; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m6A_site_448842
mod ID: M6ASITE042044		Click to Show/Hide the Full List
mod site	chr19:49640044-49640045:-		[4]
Sequence	GGGCGGCCCCGGGGCGGGGGACCTGGGCCCGGGGACCCCCC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; A549; U2OS; fibroblasts; H1299; Jurkat; CD4T; GSC-11; HEK293T; HEK293A-TOA; MSC; iSLK; TIME; TREX; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000601532.1; ENST00000246792.4
External Link	RMBase: m6A_site_448843
mod ID: M6ASITE042045		Click to Show/Hide the Full List
mod site	chr19:49640073-49640074:-		[4]
Sequence	GCAGCGGGGCGGCGTCCGGGACAGGGCGGGGGCGGCCCCGG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; A549; U2OS; fibroblasts; H1299; Jurkat; GSC-11; HEK293T; HEK293A-TOA; MSC; iSLK; TIME; TREX; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000246792.4; ENST00000601532.1
External Link	RMBase: m6A_site_448844

Ref 1	Protein lysine methyltransferase G9a inhibitors: design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines. J Med Chem. 2010 Aug 12;53(15):5844-57. doi: 10.1021/jm100478y.
Ref 2	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 3	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 4	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 5	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 6	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

Visitor Map