m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01459)

Target Name	Ubiquitin thioesterase OTUB1 (OTUB1)
Synonyms	EC 3.4.19.12; Deubiquitinating enzyme OTUB1; OTU domain-containing ubiquitin aldehyde-binding protein 1; Otubain-1; hOTU1; Ubiquitin-specific-processing protease OTUB1 Click to Show/Hide
Gene Name	OTUB1
Chromosomal Location	11q13.1
Family	Peptidase C65 family
Function	Hydrolase that can specifically remove 'Lys-48'-linked conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation (PubMed:12704427, PubMed:14661020, PubMed:12401499, PubMed:23827681). Regulator of T-cell anergy, a phenomenon that occurs when T-cells are rendered unresponsive to antigen rechallenge and no longer respond to their cognate antigen (PubMed:14661020). Acts via its interaction with RNF128/GRAIL, a crucial inductor of CD4 T-cell anergy (PubMed:14661020). Isoform 1 destabilizes RNF128, leading to prevent anergy (PubMed:14661020). In contrast, isoform 2 stabilizes RNF128 and promotes anergy (PubMed:14661020). Surprisingly, it regulates RNF128-mediated ubiquitination, but does not deubiquitinate polyubiquitinated RNF128 (PubMed:14661020). Deubiquitinates estrogen receptor alpha (ESR1) (PubMed:19383985). Mediates deubiquitination of 'Lys-48'-linked polyubiquitin chains, but not 'Lys-63'-linked polyubiquitin chains (PubMed:19211026, PubMed:23827681, PubMed:18954305). Not able to cleave di-ubiquitin (PubMed:23827681, PubMed:18954305). Also capable of removing NEDD8 from NEDD8 conjugates, but with a much lower preference compared to 'Lys-48'-linked ubiquitin (PubMed:23827681, PubMed:18954305). Click to Show/Hide
Gene ID	55611
Uniprot ID	OTUB1_HUMAN
HGNC ID	HGNC:23077
KEGG ID	hsa:55611

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01459)

Ubiquitin thioesterase OTUB1 (OTUB1)

Adenosine-to-Inosine editing (A-to-I)

In total 2 m6A sequence/site(s) in this target gene
mod ID: A2ISITE004851		Click to Show/Hide the Full List
mod site	chr11:63992055-63992056:+		[2]
Sequence	GGTGAAACCTCGTCTCTACTAAAAATACAAAATTAGCCGGG
Transcript ID List	rmsk_3566251; ENST00000301453.7; ENST00000535715.5; ENST00000428192.6; ENST00000422031.6; ENST00000543004.5; ENST00000541478.5; ENST00000538426.5; ENST00000543988.1; ENST00000535140.1
External Link	RMBase: RNA-editing_site_22377
mod ID: A2ISITE004852		Click to Show/Hide the Full List
mod site	chr11:63992619-63992620:+		[2]
Sequence	GAGTGCAATGGCACCATCTCAGCTCACTGCAACCTCCACCT
Transcript ID List	ENST00000428192.6; ENST00000541478.5; ENST00000422031.6; ENST00000538426.5; ENST00000301453.7; ENST00000543004.5; ENST00000543988.1; ENST00000535140.1; ENST00000535715.5
External Link	RMBase: RNA-editing_site_22378

5-methylcytidine (m5C)

In total 6 m6A sequence/site(s) in this target gene
mod ID: M5CSITE005182		Click to Show/Hide the Full List
mod site	chr11:63998343-63998344:+
Sequence	TTCCCCGCCCCCTGCACATTCGGGGTCTCAGCCCCCAGGCT
Cell/Tissue List	HeLa
Seq Type List	m5C-RIP-seq
Transcript ID List	ENST00000535715.5; ENST00000538426.5; ENST00000422031.6; ENST00000301453.7; ENST00000541478.5
External Link	RMBase: m5C_site_7678
mod ID: M5CSITE005183		Click to Show/Hide the Full List
mod site	chr11:64000829-64000830:+
Sequence	GCCCACCTCCCCAGGCGGCGCCCCATCACGGGGCGGCGGCA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000535715.5
External Link	RMBase: m5C_site_7679
mod ID: M5CSITE005184		Click to Show/Hide the Full List
mod site	chr11:64000830-64000831:+
Sequence	CCCACCTCCCCAGGCGGCGCCCCATCACGGGGCGGCGGCAA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000535715.5
External Link	RMBase: m5C_site_7680
mod ID: M5CSITE005185		Click to Show/Hide the Full List
mod site	chr11:64000831-64000832:+
Sequence	CCACCTCCCCAGGCGGCGCCCCATCACGGGGCGGCGGCAAA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000535715.5
External Link	RMBase: m5C_site_7681
mod ID: M5CSITE005186		Click to Show/Hide the Full List
mod site	chr11:64000832-64000833:+
Sequence	CACCTCCCCAGGCGGCGCCCCATCACGGGGCGGCGGCAAAC
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000535715.5
External Link	RMBase: m5C_site_7682
mod ID: M5CSITE005187		Click to Show/Hide the Full List
mod site	chr11:64000842-64000843:+
Sequence	GGCGGCGCCCCATCACGGGGCGGCGGCAAACCCTAGGACCC
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000535715.5
External Link	RMBase: m5C_site_7683

N6-methyladenosine (m6A)

In total 31 m6A sequence/site(s) in this target gene
mod ID: M6ASITE006388		Click to Show/Hide the Full List
mod site	chr11:63986190-63986191:+		[3]
Sequence	ATCTGCAATCACCACCGGGAACTTTGGGAGGCTGGGAAGAT
Motif Score	3.373380952
Cell/Tissue List	HepG2; MM6; peripheral-blood; iSLK; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000428192.6; ENST00000422031.6; ENST00000535715.5; ENST00000301453.7; ENST00000535431.1; ENST00000541478.5
External Link	RMBase: m6A_site_145660
mod ID: M6ASITE006389		Click to Show/Hide the Full List
mod site	chr11:63986219-63986220:+		[3]
Sequence	GGCTGGGAAGATGGAGCCAAACCAATGTGTGGGGTGGAGGT
Motif Score	2.185083333
Cell/Tissue List	HepG2; peripheral-blood; MSC; iSLK; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000535715.5; ENST00000541478.5; ENST00000422031.6; ENST00000301453.7; ENST00000535431.1; ENST00000428192.6
External Link	RMBase: m6A_site_145661
mod ID: M6ASITE006390		Click to Show/Hide the Full List
mod site	chr11:63986470-63986471:+		[4]
Sequence	TTAAAGATGGCGGCGGAGGAACCTCAGCAGCAGAAGCAGGA
Motif Score	2.930744048
Cell/Tissue List	fibroblasts; A549; HEK293A-TOA; TIME; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000535715.5; ENST00000536443.1; ENST00000541478.5; ENST00000543004.5; ENST00000301453.7; ENST00000422031.6; ENST00000447683.2; ENST00000428192.6; ENST00000535431.1; ENST00000538426.5
External Link	RMBase: m6A_site_145662
mod ID: M6ASITE006391		Click to Show/Hide the Full List
mod site	chr11:63988666-63988667:+		[5]
Sequence	CCTCCAGATTGCTGTGCAGAACCCTCTGGTGTCAGAGCGGC
Motif Score	2.930744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000535140.1; ENST00000422031.6; ENST00000543004.5; ENST00000536443.1; ENST00000428192.6; ENST00000301453.7; ENST00000535715.5; ENST00000541478.5; ENST00000543988.1; ENST00000538426.5; ENST00000447683.2
External Link	RMBase: m6A_site_145663
mod ID: M6ASITE006392		Click to Show/Hide the Full List
mod site	chr11:63988705-63988706:+		[6]
Sequence	GCTGGAGCTCTCGGTCCTATACAAGGAGTATGCTGAAGATG
Motif Score	2.110482143
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000422031.6; ENST00000301453.7; ENST00000447683.2; ENST00000541478.5; ENST00000538426.5; ENST00000535140.1; ENST00000536443.1; ENST00000543988.1; ENST00000535715.5; ENST00000428192.6; ENST00000543004.5
External Link	RMBase: m6A_site_145664
mod ID: M6ASITE006393		Click to Show/Hide the Full List
mod site	chr11:63988817-63988818:+		[5]
Sequence	CAGGAGGGTGCCTGCTTCAGACTTGCTTCCTGCTGGGTCTG
Motif Score	3.319380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000535715.5; ENST00000543988.1; ENST00000428192.6; ENST00000541478.5; ENST00000301453.7; ENST00000535140.1; ENST00000543004.5; ENST00000447683.2; ENST00000538426.5; ENST00000536443.1; ENST00000422031.6
External Link	RMBase: m6A_site_145665
mod ID: M6ASITE006394		Click to Show/Hide the Full List
mod site	chr11:63996536-63996537:+		[7]
Sequence	GCTGTCTCCGCAGGACCTCCACAAAAAGTACTCGTACATCC
Motif Score	2.053113095
Cell/Tissue List	kidney
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000301453.7; ENST00000428192.6; ENST00000422031.6; ENST00000535715.5; ENST00000535140.1; ENST00000541478.5; ENST00000543004.5; ENST00000543988.1; ENST00000538426.5
External Link	RMBase: m6A_site_145666
mod ID: M6ASITE006395		Click to Show/Hide the Full List
mod site	chr11:63996551-63996552:+		[6]
Sequence	CCTCCACAAAAAGTACTCGTACATCCGCAAGACCAGGCCTG
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000301453.7; ENST00000422031.6; ENST00000538426.5; ENST00000535715.5; ENST00000428192.6; ENST00000543988.1; ENST00000535140.1; ENST00000543004.5; ENST00000541478.5
External Link	RMBase: m6A_site_145667
mod ID: M6ASITE006396		Click to Show/Hide the Full List
mod site	chr11:63996917-63996918:+		[6]
Sequence	CCCAGGGCTTCACTGAATTCACAATTGAGGATTTCCACAAC
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000541478.5; ENST00000538426.5; ENST00000422031.6; ENST00000535715.5; ENST00000535140.1; ENST00000543988.1; ENST00000543004.5; ENST00000301453.7; ENST00000428192.6
External Link	RMBase: m6A_site_145668
mod ID: M6ASITE006397		Click to Show/Hide the Full List
mod site	chr11:63996936-63996937:+		[6]
Sequence	CACAATTGAGGATTTCCACAACACGGTGAGCCCTGGTGCCT
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000301453.7; ENST00000535140.1; ENST00000428192.6; ENST00000543004.5; ENST00000543988.1; ENST00000535715.5; ENST00000541478.5; ENST00000538426.5; ENST00000422031.6
External Link	RMBase: m6A_site_145669
mod ID: M6ASITE006398		Click to Show/Hide the Full List
mod site	chr11:63997056-63997057:+		[8]
Sequence	TCCGTGGCTGCAGTTCATGGACCTGATTGAGCAGGTGGAGA
Motif Score	3.622404762
Cell/Tissue List	HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000541478.5; ENST00000543988.1; ENST00000428192.6; ENST00000538426.5; ENST00000543004.5; ENST00000422031.6; ENST00000535140.1; ENST00000301453.7; ENST00000535715.5
External Link	RMBase: m6A_site_145670
mod ID: M6ASITE006399		Click to Show/Hide the Full List
mod site	chr11:63997082-63997083:+		[8]
Sequence	TTGAGCAGGTGGAGAAGCAGACCTCTGTCGCCGACCTGCTG
Motif Score	2.876744048
Cell/Tissue List	HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000422031.6; ENST00000535715.5; ENST00000543988.1; ENST00000535140.1; ENST00000428192.6; ENST00000301453.7; ENST00000538426.5; ENST00000543004.5; ENST00000541478.5
External Link	RMBase: m6A_site_145671
mod ID: M6ASITE006400		Click to Show/Hide the Full List
mod site	chr11:63997220-63997221:+		[3]
Sequence	ACTTCATCGAGGGTGGACGGACTGTCAAGGAGTTCTGCCAG
Motif Score	4.065041667
Cell/Tissue List	HepG2; H1A; H1B; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000535140.1; ENST00000535715.5; ENST00000301453.7; ENST00000428192.6; ENST00000543988.1; ENST00000541478.5; ENST00000543004.5; ENST00000538426.5; ENST00000422031.6
External Link	RMBase: m6A_site_145672
mod ID: M6ASITE006401		Click to Show/Hide the Full List
mod site	chr11:63997379-63997380:+		[7]
Sequence	CATGTGCAAGGAGAGCGACCACATCCACATCATTGCGCTGG
Motif Score	2.053113095
Cell/Tissue List	HEK293; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000543988.1; ENST00000541478.5; ENST00000301453.7; ENST00000535715.5; ENST00000543004.5; ENST00000538426.5; ENST00000422031.6; ENST00000535140.1; ENST00000428192.6
External Link	RMBase: m6A_site_145673
mod ID: M6ASITE006402		Click to Show/Hide the Full List
mod site	chr11:63997385-63997386:+		[6]
Sequence	CAAGGAGAGCGACCACATCCACATCATTGCGCTGGCCCAGG
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000543988.1; ENST00000543004.5; ENST00000422031.6; ENST00000541478.5; ENST00000538426.5; ENST00000535140.1; ENST00000535715.5; ENST00000428192.6; ENST00000301453.7
External Link	RMBase: m6A_site_145674
mod ID: M6ASITE006403		Click to Show/Hide the Full List
mod site	chr11:63997433-63997434:+		[7]
Sequence	CGTGTCCATCCAGGTGGAGTACATGGACCGCGGCGAGGGCG
Motif Score	2.856142857
Cell/Tissue List	kidney; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000543988.1; ENST00000428192.6; ENST00000541478.5; ENST00000535715.5; ENST00000301453.7; ENST00000538426.5; ENST00000422031.6; ENST00000543004.5
External Link	RMBase: m6A_site_145675
mod ID: M6ASITE006404		Click to Show/Hide the Full List
mod site	chr11:63997439-63997440:+		[8]
Sequence	CATCCAGGTGGAGTACATGGACCGCGGCGAGGGCGGCACCA
Motif Score	3.622404762
Cell/Tissue List	HepG2; HeLa; H1A; H1B; A549; Huh7; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000541478.5; ENST00000428192.6; ENST00000301453.7; ENST00000543004.5; ENST00000422031.6; ENST00000543988.1; ENST00000535715.5; ENST00000538426.5
External Link	RMBase: m6A_site_145676
mod ID: M6ASITE006405		Click to Show/Hide the Full List
mod site	chr11:63997469-63997470:+		[7]
Sequence	GGGCGGCACCACCAATCCGCACATCTTCCCTGAGGGCTCCG
Motif Score	2.830589286
Cell/Tissue List	kidney; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000301453.7; ENST00000543004.5; ENST00000535715.5; ENST00000543988.1; ENST00000422031.6; ENST00000538426.5; ENST00000428192.6; ENST00000541478.5
External Link	RMBase: m6A_site_145677
mod ID: M6ASITE006406		Click to Show/Hide the Full List
mod site	chr11:63997521-63997522:+		[7]
Sequence	TACCTTCTCTACCGGCCTGGACACTACGATATCCTCTACAA
Motif Score	3.643047619
Cell/Tissue List	HEK293; kidney; liver; hESC-HEK293T; HepG2; HeLa; hESCs; A549; Huh7; AML
Seq Type List	m6A-REF-seq; MAZTER-seq; m6A-seq; MeRIP-seq; miCLIP
Transcript ID List	ENST00000535715.5; ENST00000543004.5; ENST00000422031.6; ENST00000541478.5; ENST00000543988.1; ENST00000538426.5; ENST00000428192.6; ENST00000301453.7
External Link	RMBase: m6A_site_145678
mod ID: M6ASITE006407		Click to Show/Hide the Full List
mod site	chr11:63997538-63997539:+		[6]
Sequence	TGGACACTACGATATCCTCTACAAATAGGGCTGGCTCCAGC
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000543988.1; ENST00000428192.6; ENST00000538426.5; ENST00000543004.5; ENST00000535715.5; ENST00000541478.5; ENST00000422031.6; ENST00000301453.7
External Link	RMBase: m6A_site_145679
mod ID: M6ASITE006408		Click to Show/Hide the Full List
mod site	chr11:63997597-63997598:+		[6]
Sequence	CCCCCTCTGCCAGGCGCTAGACATGTACAGAGGTTTTTCTG
Motif Score	2.897386905
Cell/Tissue List	hESC-HEK293T; HepG2; HeLa; hESCs; A549; Huh7
Seq Type List	MAZTER-seq; m6A-seq; MeRIP-seq
Transcript ID List	ENST00000428192.6; ENST00000541478.5; ENST00000538426.5; ENST00000543988.1; ENST00000301453.7; ENST00000543004.5; ENST00000535715.5; ENST00000422031.6
External Link	RMBase: m6A_site_145680
mod ID: M6ASITE006409		Click to Show/Hide the Full List
mod site	chr11:63997657-63997658:+		[6]
Sequence	TTCACCCCCTTCTTCCTGTCACATGACCCCCCCCCATGTTT
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000301453.7; ENST00000428192.6; ENST00000535715.5; ENST00000543988.1; ENST00000538426.5; ENST00000422031.6; ENST00000541478.5; ENST00000543004.5
External Link	RMBase: m6A_site_145681
mod ID: M6ASITE006410		Click to Show/Hide the Full List
mod site	chr11:63997931-63997932:+		[5]
Sequence	ATCCTGGAAGTTCCTTAGGGACTTGCCCAGGGTCCCAGGGC
Motif Score	4.065041667
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000538426.5; ENST00000422031.6; ENST00000301453.7; ENST00000541478.5; ENST00000535715.5; ENST00000543004.5
External Link	RMBase: m6A_site_145682
mod ID: M6ASITE006411		Click to Show/Hide the Full List
mod site	chr11:63997957-63997958:+		[6]
Sequence	CCAGGGTCCCAGGGCCACCCACACTTCATCTGCTCCCTCAT
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000543004.5; ENST00000541478.5; ENST00000538426.5; ENST00000535715.5; ENST00000301453.7; ENST00000422031.6
External Link	RMBase: m6A_site_145683
mod ID: M6ASITE006412		Click to Show/Hide the Full List
mod site	chr11:63998011-63998012:+		[5]
Sequence	ACGTCCCGGCTGGGCCCCAGACCCCAGCTTCCTGCCCTCCA
Motif Score	2.876744048
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000538426.5; ENST00000543004.5; ENST00000301453.7; ENST00000541478.5; ENST00000422031.6; ENST00000535715.5
External Link	RMBase: m6A_site_145684
mod ID: M6ASITE006413		Click to Show/Hide the Full List
mod site	chr11:63998085-63998086:+		[5]
Sequence	AGGGGCCTTTGTGAGGCTGGACCCGGCTCAGGGCAGGTGGA
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000422031.6; ENST00000301453.7; ENST00000538426.5; ENST00000543004.5; ENST00000535715.5; ENST00000541478.5
External Link	RMBase: m6A_site_145685
mod ID: M6ASITE006414		Click to Show/Hide the Full List
mod site	chr11:63998279-63998280:+		[9]
Sequence	GCACCCCCTCTGCTTGGGCCACGGTGTCTCTGCATTGCCTG
Motif Score	2.027047619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000538426.5; ENST00000543004.5; ENST00000535715.5; ENST00000541478.5; ENST00000422031.6; ENST00000301453.7
External Link	RMBase: m6A_site_145686
mod ID: M6ASITE006415		Click to Show/Hide the Full List
mod site	chr11:63998338-63998339:+		[6]
Sequence	TTTTCTTCCCCGCCCCCTGCACATTCGGGGTCTCAGCCCCC
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000535715.5; ENST00000538426.5; ENST00000422031.6; ENST00000301453.7; ENST00000541478.5; ENST00000543004.5
External Link	RMBase: m6A_site_145687
mod ID: M6ASITE006416		Click to Show/Hide the Full List
mod site	chr11:63998400-63998401:+		[5]
Sequence	CAGGCCCTCAATAAATGTGAACTGCTGCTGCCGCCTCTGCC
Motif Score	3.373380952
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000301453.7; ENST00000535715.5; ENST00000422031.6; ENST00000538426.5
External Link	RMBase: m6A_site_145688
mod ID: M6ASITE006417		Click to Show/Hide the Full List
mod site	chr11:64001433-64001434:+		[10]
Sequence	CAGGCGGGCATCAAGAGAGGACCATCATTCCCCATTTTACA
Motif Score	3.622404762
Cell/Tissue List	MT4
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000535715.5; ENST00000536943.1
External Link	RMBase: m6A_site_145700
mod ID: M6ASITE006418		Click to Show/Hide the Full List
mod site	chr11:64001459-64001460:+		[10]
Sequence	ATTCCCCATTTTACAGATGGACAAACCAAGGCCACCTTCTC
Motif Score	3.643047619
Cell/Tissue List	MT4
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000535715.5; ENST00000536943.1
External Link	RMBase: m6A_site_145701

Ref 1	US patent application no. 5,843,738, Oligonucleotide modulation of cell adhesion.
Ref 2	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 3	Efficacy of MEK inhibition in patients with histiocytic neoplasms. Nature. 2019 Mar;567(7749):521-524. doi: 10.1038/s41586-019-1012-y. Epub 2019 Mar 13.
Ref 4	Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. Cell Rep. 2014 Jul 10;8(1):284-96. doi: 10.1016/j.celrep.2014.05.048. Epub 2014 Jun 26.
Ref 5	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 6	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 7	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
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Ref 10	Dynamics of the human and viral m(6)A RNA methylomes during HIV-1 infection of T cells. Nat Microbiol. 2016 Feb 22;1:16011. doi: 10.1038/nmicrobiol.2016.11.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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