m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01437)

Target Name	Serine/threonine-protein kinase Nek7 (NEK7)
Synonyms	EC 2.7.11.34; Never in mitosis A-related kinase 7; NimA-related protein kinase 7 Click to Show/Hide
Gene Name	NEK7
Chromosomal Location	1q31.3
Family	Protein kinase superfamily, NEK Ser/Thr protein kinase family, NIMA subfamily
Function	Protein kinase which plays an important role in mitotic cell cycle progression (PubMed:17101132, PubMed:31409757, PubMed:19941817). Required for microtubule nucleation activity of the centrosome, robust mitotic spindle formation and cytokinesis (PubMed:17586473, PubMed:19414596, PubMed:31409757, PubMed:19941817, PubMed:26522158). Phosphorylates EML4 at 'Ser-146', promoting its dissociation from microtubules during mitosis which is required for efficient chromosome congression (PubMed:31409757). Phosphorylates RPS6KB1 (By similarity). Acts as an essential activator of the NLRP3 inflammasome assembly independently of its kinase activity (PubMed:26642356, PubMed:36442502). Acts by unlocking NLRP3 following NLRP3 tranlocation into the microtubule organizing center (MTOC), relieving NLRP3 autoinhibition and promoting formation of the NLRP3:PYCARD complex, and activation of CASP1 (PubMed:26642356, PubMed:31189953, PubMed:36442502). Serves as a cellular switch that enforces mutual exclusivity of the inflammasome response and cell division: interaction with NEK9 prevents interaction with NLRP3 and activation of the inflammasome during mitosis (PubMed:26642356, PubMed:31189953). Click to Show/Hide
Gene ID	140609
Uniprot ID	NEK7_HUMAN
HGNC ID	HGNC:13386
KEGG ID	hsa:140609

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01437)

Serine/threonine-protein kinase Nek7 (NEK7)

Adenosine-to-Inosine editing (A-to-I)

In total 25 m6A sequence/site(s) in this target gene
mod ID: A2ISITE001037		Click to Show/Hide the Full List
mod site	chr1:198171039-198171040:+		[3]
Sequence	CCTCCTGAAGTGTTGAGATTACAGGCATGAGCCACTGCACC
Transcript ID List	ENST00000367383.5; ENST00000442588.5; ENST00000367385.9; ENST00000538004.5
External Link	RMBase: RNA-editing_site_11255
mod ID: A2ISITE001048		Click to Show/Hide the Full List
mod site	chr1:198173226-198173227:+		[4]
Sequence	TTGCTTGAGACTGGGAGTTCAAGACCAGCATGAGCAACATA
Transcript ID List	ENST00000538004.5; rmsk_348663; ENST00000442588.5; ENST00000367383.5; ENST00000367385.9
External Link	RMBase: RNA-editing_site_11256
mod ID: A2ISITE001059		Click to Show/Hide the Full List
mod site	chr1:198265807-198265808:+		[3]
Sequence	ATTGATATGTGGTTGGATATATGTACATACATTAGTACATA
Transcript ID List	ENST00000538004.5; ENST00000367385.9
External Link	RMBase: RNA-editing_site_11257
mod ID: A2ISITE001070		Click to Show/Hide the Full List
mod site	chr1:198265866-198265867:+		[3]
Sequence	TGGATATGTGTACATACATTAGTACATATGTCTTTAAAAAG
Transcript ID List	ENST00000538004.5; ENST00000367385.9
External Link	RMBase: RNA-editing_site_11258
mod ID: A2ISITE001081		Click to Show/Hide the Full List
mod site	chr1:198265881-198265882:+		[3]
Sequence	ACATTAGTACATATGTCTTTAAAAAGTATACATATAAACAT
Transcript ID List	ENST00000538004.5; ENST00000367385.9
External Link	RMBase: RNA-editing_site_11259
mod ID: A2ISITE001092		Click to Show/Hide the Full List
mod site	chr1:198265902-198265903:+		[3]
Sequence	AAAAGTATACATATAAACATACTATATATTATGTTACTTAA
Transcript ID List	ENST00000538004.5; ENST00000367385.9
External Link	RMBase: RNA-editing_site_11260
mod ID: A2ISITE001103		Click to Show/Hide the Full List
mod site	chr1:198265912-198265913:+		[4]
Sequence	ATATAAACATACTATATATTATGTTACTTAACCATCATAAT
Transcript ID List	ENST00000538004.5; ENST00000367385.9
External Link	RMBase: RNA-editing_site_11261
mod ID: A2ISITE001114		Click to Show/Hide the Full List
mod site	chr1:198265939-198265940:+		[4]
Sequence	TTAACCATCATAATAAAACTATATGACAGGTATTACTGACC
Transcript ID List	ENST00000538004.5; ENST00000367385.9
External Link	RMBase: RNA-editing_site_11262
mod ID: A2ISITE001125		Click to Show/Hide the Full List
mod site	chr1:198266661-198266662:+		[3]
Sequence	GAGCCAGTTTCTACATCAATAAAATTGGGTCAGTAATACCT
Transcript ID List	rmsk_348808; ENST00000367385.9; ENST00000538004.5
External Link	RMBase: RNA-editing_site_11263
mod ID: A2ISITE001127		Click to Show/Hide the Full List
mod site	chr1:198266689-198266690:+		[4]
Sequence	GTCAGTAATACCTGTCTTACAGTGTTGTTATGATGGTTAAG
Transcript ID List	ENST00000367385.9; ENST00000538004.5; rmsk_348808
External Link	RMBase: RNA-editing_site_11264
mod ID: A2ISITE001128		Click to Show/Hide the Full List
mod site	chr1:198266707-198266708:+		[3]
Sequence	ACAGTGTTGTTATGATGGTTAAGTAATATAATATATAGTAT
Transcript ID List	ENST00000367385.9; ENST00000538004.5; rmsk_348808
External Link	RMBase: RNA-editing_site_11265
mod ID: A2ISITE001129		Click to Show/Hide the Full List
mod site	chr1:198266708-198266709:+		[3]
Sequence	CAGTGTTGTTATGATGGTTAAGTAATATAATATATAGTATG
Transcript ID List	rmsk_348808; ENST00000367385.9; ENST00000538004.5
External Link	RMBase: RNA-editing_site_11266
mod ID: A2ISITE001130		Click to Show/Hide the Full List
mod site	chr1:198266717-198266718:+		[3]
Sequence	TATGATGGTTAAGTAATATAATATATAGTATGTTTATATAT
Transcript ID List	rmsk_348808; ENST00000538004.5; ENST00000367385.9
External Link	RMBase: RNA-editing_site_11267
mod ID: A2ISITE001131		Click to Show/Hide the Full List
mod site	chr1:198266726-198266727:+		[3]
Sequence	TAAGTAATATAATATATAGTATGTTTATATATATACTTTTT
Transcript ID List	ENST00000538004.5; ENST00000367385.9
External Link	RMBase: RNA-editing_site_11268
mod ID: A2ISITE001132		Click to Show/Hide the Full List
mod site	chr1:198266736-198266737:+		[3]
Sequence	AATATATAGTATGTTTATATATATACTTTTTAAAGACATAT
Transcript ID List	ENST00000538004.5; ENST00000367385.9
External Link	RMBase: RNA-editing_site_11269
mod ID: A2ISITE001133		Click to Show/Hide the Full List
mod site	chr1:198266747-198266748:+		[4]
Sequence	TGTTTATATATATACTTTTTAAAGACATATGTACAAATGTA
Transcript ID List	ENST00000367385.9; ENST00000538004.5
External Link	RMBase: RNA-editing_site_11270
mod ID: A2ISITE001134		Click to Show/Hide the Full List
mod site	chr1:198281311-198281312:+		[4]
Sequence	TCTTCTCAGAGTTGGCACTGAAAAGTAATTGAAAACGTGGT
Transcript ID List	ENST00000367385.9; ENST00000538004.5; ENST00000493790.1
External Link	RMBase: RNA-editing_site_11271
mod ID: A2ISITE001135		Click to Show/Hide the Full List
mod site	chr1:198281312-198281313:+		[4]
Sequence	CTTCTCAGAGTTGGCACTGAAAAGTAATTGAAAACGTGGTG
Transcript ID List	ENST00000367385.9; ENST00000538004.5; ENST00000493790.1
External Link	RMBase: RNA-editing_site_11272
mod ID: A2ISITE001136		Click to Show/Hide the Full List
mod site	chr1:198281318-198281319:+		[4]
Sequence	AGAGTTGGCACTGAAAAGTAATTGAAAACGTGGTGACCTAT
Transcript ID List	ENST00000367385.9; ENST00000538004.5; ENST00000493790.1
External Link	RMBase: RNA-editing_site_11273
mod ID: A2ISITE001137		Click to Show/Hide the Full List
mod site	chr1:198281833-198281834:+		[4]
Sequence	GTATCTTTTCATTCCATAATAAATCAACATACAATAAAACC
Transcript ID List	ENST00000538004.5; ENST00000367385.9; ENST00000493790.1
External Link	RMBase: RNA-editing_site_11274
mod ID: A2ISITE001138		Click to Show/Hide the Full List
mod site	chr1:198281834-198281835:+		[4]
Sequence	TATCTTTTCATTCCATAATAAATCAACATACAATAAAACCT
Transcript ID List	ENST00000367385.9; ENST00000493790.1; ENST00000538004.5
External Link	RMBase: RNA-editing_site_11275
mod ID: A2ISITE001139		Click to Show/Hide the Full List
mod site	chr1:198281880-198281881:+		[4]
Sequence	CTGTCTTCTGTAGCAAATAAAGTTGTATAGGTGGCCACATT
Transcript ID List	ENST00000538004.5; ENST00000367385.9; ENST00000493790.1
External Link	RMBase: RNA-editing_site_11276
mod ID: A2ISITE001140		Click to Show/Hide the Full List
mod site	chr1:198281888-198281889:+		[4]
Sequence	TGTAGCAAATAAAGTTGTATAGGTGGCCACATTTCCAATTA
Transcript ID List	ENST00000367385.9; ENST00000538004.5; ENST00000493790.1
External Link	RMBase: RNA-editing_site_11277
mod ID: A2ISITE001141		Click to Show/Hide the Full List
mod site	chr1:198281898-198281899:+		[4]
Sequence	AAAGTTGTATAGGTGGCCACATTTCCAATTAGTTTTCAGAA
Transcript ID List	ENST00000367385.9; ENST00000493790.1; ENST00000538004.5
External Link	RMBase: RNA-editing_site_11278
mod ID: A2ISITE001142		Click to Show/Hide the Full List
mod site	chr1:198281908-198281909:+		[3]
Sequence	AGGTGGCCACATTTCCAATTAGTTTTCAGAACCAATTCTTA
Transcript ID List	ENST00000367385.9; ENST00000538004.5; ENST00000493790.1
External Link	RMBase: RNA-editing_site_11279

5-methylcytidine (m5C)

In total 9 m6A sequence/site(s) in this target gene
mod ID: M5CSITE004472		Click to Show/Hide the Full List
mod site	chr1:198157072-198157073:+		[5]
Sequence	CCGCCGCTAGGCTCGCACTCCGGACGCGCCTCGCAGTGCGC
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000367385.9; ENST00000538004.5; ENST00000442588.5
External Link	RMBase: m5C_site_4343
mod ID: M5CSITE004477		Click to Show/Hide the Full List
mod site	chr1:198157247-198157248:+		[5]
Sequence	CGCCCAAGGTCTCTCGCGGGCGGGAGAACGGAAAACTCCCA
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000442588.5; ENST00000367383.5; ENST00000367385.9; ENST00000538004.5
External Link	RMBase: m5C_site_4344
mod ID: M5CSITE004478		Click to Show/Hide the Full List
mod site	chr1:198262605-198262606:+
Sequence	AATGGATGCCAAAGCACGTGCTGATTGCATCAAAGAAATAG
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000367385.9; ENST00000391974.3; ENST00000538004.5
External Link	RMBase: m5C_site_4345
mod ID: M5CSITE004479		Click to Show/Hide the Full List
mod site	chr1:198262615-198262616:+
Sequence	AAAGCACGTGCTGATTGCATCAAAGAAATAGATCTTCTTAA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000391974.3; ENST00000538004.5; ENST00000367385.9
External Link	RMBase: m5C_site_4346
mod ID: M5CSITE004480		Click to Show/Hide the Full List
mod site	chr1:198262631-198262632:+
Sequence	GCATCAAAGAAATAGATCTTCTTAAGGTAATTAATGAACTG
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000367385.9; ENST00000538004.5
External Link	RMBase: m5C_site_4347
mod ID: M5CSITE004481		Click to Show/Hide the Full List
mod site	chr1:198264124-198264125:+
Sequence	TGCCTGTTTTATTTTCTCAGCAACTCAACCATCCAAATGTA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000367385.9; ENST00000538004.5
External Link	RMBase: m5C_site_4348
mod ID: M5CSITE004482		Click to Show/Hide the Full List
mod site	chr1:198264127-198264128:+
Sequence	CTGTTTTATTTTCTCAGCAACTCAACCATCCAAATGTAATA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000367385.9; ENST00000538004.5
External Link	RMBase: m5C_site_4349
mod ID: M5CSITE004483		Click to Show/Hide the Full List
mod site	chr1:198264132-198264133:+
Sequence	TTATTTTCTCAGCAACTCAACCATCCAAATGTAATAAAATA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000367385.9; ENST00000538004.5
External Link	RMBase: m5C_site_4350
mod ID: M5CSITE004484		Click to Show/Hide the Full List
mod site	chr1:198264165-198264166:+
Sequence	ATAAAATATTATGCATCATTCATTGAAGATAATGAACTAAA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000367385.9; ENST00000538004.5
External Link	RMBase: m5C_site_4351

N6-methyladenosine (m6A)

In total 64 m6A sequence/site(s) in this target gene
mod ID: M6ASITE073594		Click to Show/Hide the Full List
mod site	chr1:198157261-198157262:+		[6]
Sequence	CGCGGGCGGGAGAACGGAAAACTCCCAACTTCCTGGTGAGT
Motif Score	2.627720238
Cell/Tissue List	GSC-11; HEK293T
Seq Type List	m6A-seq
Transcript ID List	ENST00000538004.5; ENST00000442588.5; ENST00000367385.9; ENST00000367383.5
External Link	RMBase: m6A_site_70620
mod ID: M6ASITE073595		Click to Show/Hide the Full List
mod site	chr1:198206883-198206884:+		[6]
Sequence	ATAAGAGTAGGAATTCATAAACAACTGTCCTCATAGTGGGC
Motif Score	2.20572619
Cell/Tissue List	GSC-11; HEK293T
Seq Type List	m6A-seq
Transcript ID List	ENST00000544035.5; ENST00000367385.9; ENST00000538004.5; ENST00000442588.5; ENST00000367383.5
External Link	RMBase: m6A_site_70621
mod ID: M6ASITE073596		Click to Show/Hide the Full List
mod site	chr1:198253110-198253111:+		[7]
Sequence	GAAAAGAAAATTGGTCGCGGACAATTTAGTGAAGTTTATAG
Motif Score	3.643047619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000367385.9; ENST00000544035.5; ENST00000367383.5; ENST00000391974.3; ENST00000538004.5
External Link	RMBase: m6A_site_70622
mod ID: M6ASITE073597		Click to Show/Hide the Full List
mod site	chr1:198264185-198264186:+		[7]
Sequence	CATTGAAGATAATGAACTAAACATAGTTTTGGAACTAGCAG
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000367385.9; ENST00000538004.5
External Link	RMBase: m6A_site_70623
mod ID: M6ASITE073598		Click to Show/Hide the Full List
mod site	chr1:198278037-198278038:+		[7]
Sequence	CAGCTTTGCAGTGCATTGGAACACATGCATTCTCGAAGAGT
Motif Score	2.951386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000493790.1; ENST00000367385.9; ENST00000538004.5
External Link	RMBase: m6A_site_70624
mod ID: M6ASITE073599		Click to Show/Hide the Full List
mod site	chr1:198278960-198278961:+		[8]
Sequence	CATTTATTCACAGATATAAAACCAGCTAATGTGTTCATTAC
Motif Score	2.185083333
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000493790.1; ENST00000367385.9; ENST00000538004.5
External Link	RMBase: m6A_site_70625
mod ID: M6ASITE073600		Click to Show/Hide the Full List
mod site	chr1:198278999-198279000:+		[8]
Sequence	ACAGCCACTGGGGTGGTAAAACTTGGAGATCTTGGGCTTGG
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000538004.5; ENST00000367385.9; ENST00000493790.1
External Link	RMBase: m6A_site_70626
mod ID: M6ASITE073601		Click to Show/Hide the Full List
mod site	chr1:198279039-198279040:+		[8]
Sequence	GCCGGTTTTTCAGCTCAAAAACCACAGCTGCACATTCTTTA
Motif Score	2.185083333
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000367385.9; ENST00000493790.1; ENST00000538004.5
External Link	RMBase: m6A_site_70627
mod ID: M6ASITE073602		Click to Show/Hide the Full List
mod site	chr1:198293007-198293008:+		[7]
Sequence	TGGATACAACTTCAAATCTGACATCTGGTCTCTTGGCTGTC
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000493790.1; ENST00000538004.5; ENST00000367385.9
External Link	RMBase: m6A_site_70628
mod ID: M6ASITE073603		Click to Show/Hide the Full List
mod site	chr1:198297137-198297138:+		[7]
Sequence	ATTTTACAGATGGCTGCATTACAAAGTCCTTTCTATGGTGA
Motif Score	2.07285119
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000493790.1; ENST00000538004.5; ENST00000367385.9
External Link	RMBase: m6A_site_70629
mod ID: M6ASITE073604		Click to Show/Hide the Full List
mod site	chr1:198297194-198297195:+		[8]
Sequence	TCACTGTGTAAGAAGATAGAACAGTGTGACTACCCACCTCT
Motif Score	2.951386905
Cell/Tissue List	HeLa; CD34; BGC823
Seq Type List	m6A-seq
Transcript ID List	ENST00000367385.9; ENST00000493790.1; ENST00000538004.5
External Link	RMBase: m6A_site_70630
mod ID: M6ASITE073605		Click to Show/Hide the Full List
mod site	chr1:198319522-198319523:+		[7]
Sequence	CATGCACTGCAAGCAGCTAAACATGCAAGATCATGAAGAGT
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T; BGC823
Seq Type List	MAZTER-seq; m6A-seq
Transcript ID List	rmsk_348860; ENST00000493790.1; ENST00000367385.9
External Link	RMBase: m6A_site_70631
mod ID: M6ASITE073606		Click to Show/Hide the Full List
mod site	chr1:198319709-198319710:+		[9]
Sequence	CTCCTTGCAACCCCCAAATGACTTTGGAATAACTGAATTGC
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000367385.9; ENST00000493790.1
External Link	RMBase: m6A_site_70632
mod ID: M6ASITE073607		Click to Show/Hide the Full List
mod site	chr1:198319750-198319751:+		[8]
Sequence	ATGTTAGGAGAGAAAATGAAACATGATGGTTTTGAATGGCT
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T; Huh7
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70633
mod ID: M6ASITE073608		Click to Show/Hide the Full List
mod site	chr1:198319824-198319825:+		[8]
Sequence	GATAAATTGTGTTTAGATAGACTGTCAGTGCCAAATATTGA
Motif Score	3.319380952
Cell/Tissue List	HeLa; HEK293T; HepG2; hNPCs; fibroblasts; GM12878; Huh7; HEK293A-TOA; iSLK; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70634
mod ID: M6ASITE073609		Click to Show/Hide the Full List
mod site	chr1:198319859-198319860:+		[7]
Sequence	TATTGAAGGTGCAGCTTGGCACACATCAGAATAGACTCATA
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70635
mod ID: M6ASITE073610		Click to Show/Hide the Full List
mod site	chr1:198319873-198319874:+		[8]
Sequence	CTTGGCACACATCAGAATAGACTCATACCTGAGAAAAAGTA
Motif Score	3.319380952
Cell/Tissue List	HeLa; HEK293T; HepG2; hNPCs; GM12878; Huh7; Jurkat; HEK293A-TOA; iSLK; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70636
mod ID: M6ASITE073611		Click to Show/Hide the Full List
mod site	chr1:198319899-198319900:+		[8]
Sequence	ACCTGAGAAAAAGTATCTGAACATGTGACTTGTTTCTTTTT
Motif Score	2.951386905
Cell/Tissue List	HeLa; HEK293T; HepG2; hNPCs; GM12878; Huh7; Jurkat; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq; DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70637
mod ID: M6ASITE073612		Click to Show/Hide the Full List
mod site	chr1:198319906-198319907:+		[9]
Sequence	AAAAAGTATCTGAACATGTGACTTGTTTCTTTTTTAGTAAT
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70638
mod ID: M6ASITE073613		Click to Show/Hide the Full List
mod site	chr1:198319933-198319934:+		[8]
Sequence	TCTTTTTTAGTAATTTATGGACATTGAGATGAACACAATTG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T; HepG2; hNPCs; GM12878; CD8T; Huh7; Jurkat; HEK293A-TOA; iSLK; MSC; TIME; TREX; AML
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq; m6A-CLIP/IP; miCLIP
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70639
mod ID: M6ASITE073614		Click to Show/Hide the Full List
mod site	chr1:198319945-198319946:+		[8]
Sequence	ATTTATGGACATTGAGATGAACACAATTGTGAACTTTTGTG
Motif Score	2.951386905
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T; HepG2; hNPCs; GM12878; Huh7; Jurkat; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70640
mod ID: M6ASITE073615		Click to Show/Hide the Full List
mod site	chr1:198319957-198319958:+		[8]
Sequence	TGAGATGAACACAATTGTGAACTTTTGTGAAGATTTTATTT
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T; HepG2; hNPCs; GM12878; Huh7; Jurkat; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70641
mod ID: M6ASITE073616		Click to Show/Hide the Full List
mod site	chr1:198319982-198319983:+		[9]
Sequence	TGTGAAGATTTTATTTTTAAACGTTTGAAGTACTAGTTTTA
Motif Score	2.179660714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70642
mod ID: M6ASITE073617		Click to Show/Hide the Full List
mod site	chr1:198320050-198320051:+		[7]
Sequence	GATTCTTATGATAAATGTAGACACAAACTATTTGAGAAACA
Motif Score	2.897386905
Cell/Tissue List	hESC-HEK293T; Huh7; TREX
Seq Type List	MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70643
mod ID: M6ASITE073618		Click to Show/Hide the Full List
mod site	chr1:198320056-198320057:+		[10]
Sequence	TATGATAAATGTAGACACAAACTATTTGAGAAACATTTAGA
Motif Score	2.627720238
Cell/Tissue List	Huh7; TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70644
mod ID: M6ASITE073619		Click to Show/Hide the Full List
mod site	chr1:198320068-198320069:+		[10]
Sequence	AGACACAAACTATTTGAGAAACATTTAGAACTCTTAGCTTA
Motif Score	2.20572619
Cell/Tissue List	Huh7; TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70645
mod ID: M6ASITE073620		Click to Show/Hide the Full List
mod site	chr1:198320077-198320078:+		[9]
Sequence	CTATTTGAGAAACATTTAGAACTCTTAGCTTATACATTCAA
Motif Score	3.373380952
Cell/Tissue List	HEK293T; Huh7; TREX
Seq Type List	DART-seq; MeRIP-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70646
mod ID: M6ASITE073621		Click to Show/Hide the Full List
mod site	chr1:198320090-198320091:+		[9]
Sequence	ATTTAGAACTCTTAGCTTATACATTCAAAATGTAACTATTA
Motif Score	2.110482143
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70647
mod ID: M6ASITE073622		Click to Show/Hide the Full List
mod site	chr1:198320144-198320145:+		[7]
Sequence	GGGGACAAAATGTGAGTCAGACACTGAAGAGTTTTTTGTTT
Motif Score	2.897386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70648
mod ID: M6ASITE073623		Click to Show/Hide the Full List
mod site	chr1:198320274-198320275:+		[9]
Sequence	ATAATAATTTTTAAAGTTGCACATTGCCCAAGGCTTTTTTT
Motif Score	2.830589286
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70649
mod ID: M6ASITE073624		Click to Show/Hide the Full List
mod site	chr1:198320317-198320318:+		[9]
Sequence	GTGTTTTTATTGTTGTTTGTACATTTGAAAAATATTCTTTG
Motif Score	2.856142857
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70650
mod ID: M6ASITE073625		Click to Show/Hide the Full List
mod site	chr1:198320391-198320392:+		[9]
Sequence	ATAAATTTAAGTGCATTTTAACTCATAATTGTACACTATAA
Motif Score	2.590089286
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70651
mod ID: M6ASITE073626		Click to Show/Hide the Full List
mod site	chr1:198320403-198320404:+		[7]
Sequence	GCATTTTAACTCATAATTGTACACTATAATATAAGCCTAAG
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70652
mod ID: M6ASITE073627		Click to Show/Hide the Full List
mod site	chr1:198320543-198320544:+		[9]
Sequence	TTTATCCATTAATGTTTCATACTTTCTGAGAGTATAATACC
Motif Score	2.53247619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70653
mod ID: M6ASITE073628		Click to Show/Hide the Full List
mod site	chr1:198320693-198320694:+		[9]
Sequence	GAAGAAAGGATGTGTGTTATACTGTACCTGTGAATGTTGAT
Motif Score	2.53247619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70654
mod ID: M6ASITE073629		Click to Show/Hide the Full List
mod site	chr1:198320732-198320733:+		[9]
Sequence	ATACAGTTACAATTTATTTGACAAGGTTGTAATTCTAGAAT
Motif Score	2.859755952
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70655
mod ID: M6ASITE073630		Click to Show/Hide the Full List
mod site	chr1:198320771-198320772:+		[8]
Sequence	ATATGCTTAATAAAATGAAAACTGGCCATGACTACAGCCAG
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70656
mod ID: M6ASITE073631		Click to Show/Hide the Full List
mod site	chr1:198320793-198320794:+		[8]
Sequence	TGGCCATGACTACAGCCAGAACTGTTATGAGATTAACATTT
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70657
mod ID: M6ASITE073632		Click to Show/Hide the Full List
mod site	chr1:198320861-198320862:+		[9]
Sequence	TGTATTTGTTCATGAAGATGACTGAGATGGTAACACTTCGT
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70658
mod ID: M6ASITE073633		Click to Show/Hide the Full List
mod site	chr1:198320873-198320874:+		[7]
Sequence	TGAAGATGACTGAGATGGTAACACTTCGTGTAGCTTAAGGA
Motif Score	2.168095238
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70659
mod ID: M6ASITE073634		Click to Show/Hide the Full List
mod site	chr1:198321019-198321020:+		[8]
Sequence	GAGGAAGTCACTGTTAAAGGACTCTGTGCCATCTTACAACC
Motif Score	4.065041667
Cell/Tissue List	HeLa; A549; CD8T
Seq Type List	m6A-seq; m6A-CLIP/IP
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70660
mod ID: M6ASITE073635		Click to Show/Hide the Full List
mod site	chr1:198321034-198321035:+		[7]
Sequence	AAAGGACTCTGTGCCATCTTACAACCTTGGATGAATTATCC
Motif Score	2.07285119
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70661
mod ID: M6ASITE073636		Click to Show/Hide the Full List
mod site	chr1:198321068-198321069:+		[8]
Sequence	ATTATCCTGCCAACGTGAAAACCTCATGTTCAAAGAACACT
Motif Score	2.185083333
Cell/Tissue List	HeLa; A549
Seq Type List	m6A-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70662
mod ID: M6ASITE073637		Click to Show/Hide the Full List
mod site	chr1:198321084-198321085:+		[8]
Sequence	GAAAACCTCATGTTCAAAGAACACTTCCCTTTAGCCGATGT
Motif Score	2.951386905
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70663
mod ID: M6ASITE073638		Click to Show/Hide the Full List
mod site	chr1:198321106-198321107:+		[9]
Sequence	ACTTCCCTTTAGCCGATGTAACTGCTGGTTTTGTTTTTCAT
Motif Score	2.590089286
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70664
mod ID: M6ASITE073639		Click to Show/Hide the Full List
mod site	chr1:198321140-198321141:+		[9]
Sequence	TTTTCATATGTGTTTTTCTTACACTCATTTGAATGCTTTCA
Motif Score	2.07285119
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70665
mod ID: M6ASITE073640		Click to Show/Hide the Full List
mod site	chr1:198321172-198321173:+		[8]
Sequence	ATGCTTTCAAGCATTTGTAAACTTAAAAAATGTATAAAGGG
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70666
mod ID: M6ASITE073641		Click to Show/Hide the Full List
mod site	chr1:198321205-198321206:+		[8]
Sequence	ATAAAGGGCAAAAAGTCTGAACCCTTGTTTTCTGAAATCTA
Motif Score	2.930744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70667
mod ID: M6ASITE073642		Click to Show/Hide the Full List
mod site	chr1:198321280-198321281:+		[8]
Sequence	TTTTGGAATAGGTAAAGGAAACCTGTTTTGTTTGTTTTTCC
Motif Score	2.185083333
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70668
mod ID: M6ASITE073643		Click to Show/Hide the Full List
mod site	chr1:198321327-198321328:+		[7]
Sequence	CTAGATGCATTTTTTTTCTCACACTCTTAATGACTTTTAAC
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70669
mod ID: M6ASITE073644		Click to Show/Hide the Full List
mod site	chr1:198321329-198321330:+		[9]
Sequence	AGATGCATTTTTTTTCTCACACTCTTAATGACTTTTAACAT
Motif Score	2.506922619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70670
mod ID: M6ASITE073645		Click to Show/Hide the Full List
mod site	chr1:198321506-198321507:+		[9]
Sequence	TTCTTGCAATCTTTAAGAATACATAGATCTAAAATTCATTA
Motif Score	2.110482143
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70671
mod ID: M6ASITE073646		Click to Show/Hide the Full List
mod site	chr1:198321764-198321765:+		[9]
Sequence	GAATGGAATAATTTCAAAGAACTATGAAGATGATTTGAAGC
Motif Score	3.373380952
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70672
mod ID: M6ASITE073647		Click to Show/Hide the Full List
mod site	chr1:198321858-198321859:+		[9]
Sequence	TTTTATATTGATTAAGTTAAACTTTTGAATTGATTTGAGGA
Motif Score	2.627720238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70673
mod ID: M6ASITE073648		Click to Show/Hide the Full List
mod site	chr1:198321920-198321921:+		[9]
Sequence	CTATTCTAAACCTTATTTAGACATTGGTACCAGTTACCCAG
Motif Score	2.897386905
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70674
mod ID: M6ASITE073649		Click to Show/Hide the Full List
mod site	chr1:198322025-198322026:+		[9]
Sequence	CTATATAAATAAAGTGCTCAACAATGTGCAATGATTGTAAA
Motif Score	2.173910714
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70675
mod ID: M6ASITE073650		Click to Show/Hide the Full List
mod site	chr1:198322082-198322083:+		[9]
Sequence	AGCCATTTCATGAATGCTTTACCATTCAACATAGTATCTAT
Motif Score	2.052208333
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70676
mod ID: M6ASITE073651		Click to Show/Hide the Full List
mod site	chr1:198322090-198322091:+		[9]
Sequence	CATGAATGCTTTACCATTCAACATAGTATCTATTACAAAAC
Motif Score	2.173910714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70677
mod ID: M6ASITE073652		Click to Show/Hide the Full List
mod site	chr1:198322104-198322105:+		[9]
Sequence	CATTCAACATAGTATCTATTACAAAACACCTTTCTTGTATC
Motif Score	2.07285119
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70678
mod ID: M6ASITE073653		Click to Show/Hide the Full List
mod site	chr1:198322184-198322185:+		[9]
Sequence	TTTATTTTAACCAAAATGTTACTCACATTAAATGTTTATTC
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70679
mod ID: M6ASITE073654		Click to Show/Hide the Full List
mod site	chr1:198322235-198322236:+		[7]
Sequence	ATGTATTATGTTTTTAACCCACAAATGCATACTTACCCTGT
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70680
mod ID: M6ASITE073655		Click to Show/Hide the Full List
mod site	chr1:198322245-198322246:+		[9]
Sequence	TTTTTAACCCACAAATGCATACTTACCCTGTGCCTCATATT
Motif Score	2.53247619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70681
mod ID: M6ASITE073656		Click to Show/Hide the Full List
mod site	chr1:198322286-198322287:+		[9]
Sequence	TCAATAGTACTGTAATATGGACATCTTTTGTGAAATACTTT
Motif Score	3.643047619
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000367385.9
External Link	RMBase: m6A_site_70682
mod ID: M6ASITE073657		Click to Show/Hide the Full List
mod site	chr1:198322385-198322386:+		[7]
Sequence	TGTATAATATCCTAATATAAACAAAAATATAAAAATAAAAA
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T; Huh7
Seq Type List	MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000367385.9; rmsk_348861
External Link	RMBase: m6A_site_70683

Ref 1	P-glycoprotein and breast cancer resistance protein in acute myeloid leukaemia cells treated with the aurora-B kinase inhibitor barasertib-hQPA. BMC Cancer. 2011 Jun 16;11:254.
Ref 2	AXL receptor tyrosine kinase as a promising anti-cancer approach: functions, molecular mechanisms and clinical applications. Mol Cancer. 2019 Nov 4;18(1):153. doi: 10.1186/s12943-019-1090-3.
Ref 3	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 4	Accurate identification of A-to-I RNA editing in human by transcriptome sequencing. Genome Res. 2012 Jan;22(1):142-50. doi: 10.1101/gr.124107.111. Epub 2011 Sep 29.
Ref 5	Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6784-6789. doi: 10.1073/pnas.1817334116. Epub 2019 Mar 14.
Ref 6	m(6)A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program. Cancer Cell. 2017 Apr 10;31(4):591-606.e6. doi: 10.1016/j.ccell.2017.02.013. Epub 2017 Mar 23.
Ref 7	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 8	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 9	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 10	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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