m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01428)

Target Name	GTPase HRas (HRAS)
Synonyms	EC 3.6.5.2; H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21ras Click to Show/Hide
Gene Name	HRAS
Chromosomal Location	11p15.5
Family	Small GTPase superfamily, Ras family
Function	Involved in the activation of Ras protein signal transduction (PubMed:22821884). Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:12740440, PubMed:14500341, PubMed:9020151). Click to Show/Hide
Gene ID	3265
Uniprot ID	RASH_HUMAN
HGNC ID	HGNC:5173
KEGG ID	hsa:3265

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01428)

GTPase HRas (HRAS)

N6-methyladenosine (m6A)

In total 18 m6A sequence/site(s) in this target gene
mod ID: M6ASITE002967		Click to Show/Hide the Full List
mod site	chr11:532326-532327:-		[2]
Sequence	ACATCCCAAATGCCACCGGAACCCCAGCCCTTAGCTCCCCT
Motif Score	2.930744048
Cell/Tissue List	HeLa; HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000493230.5; ENST00000451590.5; ENST00000478324.5; ENST00000397594.5; ENST00000397596.6; ENST00000462734.1; ENST00000311189.8; ENST00000417302.5
External Link	RMBase: m6A_site_125572
mod ID: M6ASITE002968		Click to Show/Hide the Full List
mod site	chr11:532346-532347:-		[2]
Sequence	CTGTGCACAGACTGTCTTGAACATCCCAAATGCCACCGGAA
Motif Score	2.951386905
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T; HEK293A-TOA
Seq Type List	m6A-seq; DART-seq; MAZTER-seq
Transcript ID List	ENST00000493230.5; ENST00000451590.5; ENST00000417302.5; ENST00000462734.1; ENST00000478324.5; ENST00000397596.6; ENST00000397594.5; ENST00000311189.8
External Link	RMBase: m6A_site_125573
mod ID: M6ASITE002969		Click to Show/Hide the Full List
mod site	chr11:532356-532357:-		[2]
Sequence	CCCAGGGAGGCTGTGCACAGACTGTCTTGAACATCCCAAAT
Motif Score	3.319380952
Cell/Tissue List	HeLa; CD8T; A549; HEK293A-TOA
Seq Type List	m6A-seq; m6A-CLIP/IP
Transcript ID List	ENST00000451590.5; ENST00000397596.6; ENST00000478324.5; ENST00000493230.5; ENST00000462734.1; ENST00000397594.5; ENST00000417302.5; ENST00000311189.8
External Link	RMBase: m6A_site_125574
mod ID: M6ASITE002970		Click to Show/Hide the Full List
mod site	chr11:532381-532382:-		[2]
Sequence	GTGGGCCGAGGTGACTGCAGACCCTCCCAGGGAGGCTGTGC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293T; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000311189.8; ENST00000451590.5; ENST00000493230.5; ENST00000397596.6; ENST00000397594.5; ENST00000462734.1; ENST00000417302.5; ENST00000478324.5
External Link	RMBase: m6A_site_125575
mod ID: M6ASITE002971		Click to Show/Hide the Full List
mod site	chr11:532404-532405:-		[2]
Sequence	TGGAGCCCAGTCACCCCGGGACCGTGGGCCGAGGTGACTGC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HEK293T; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000311189.8; ENST00000462734.1; ENST00000493230.5; ENST00000451590.5; ENST00000417302.5; ENST00000478324.5; ENST00000397594.5; ENST00000397596.6
External Link	RMBase: m6A_site_125576
mod ID: M6ASITE002972		Click to Show/Hide the Full List
mod site	chr11:532509-532510:-		[2]
Sequence	CCGCCCAGCACAAGCTCAGGACATGGAGGTGCCGGATGCAG
Motif Score	3.643047619
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000417302.5; ENST00000397596.6; ENST00000311189.8; ENST00000397594.5; ENST00000462734.1; ENST00000451590.5; ENST00000478324.5; ENST00000493230.5
External Link	RMBase: m6A_site_125577
mod ID: M6ASITE002973		Click to Show/Hide the Full List
mod site	chr11:532520-532521:-		[3]
Sequence	TCCCTTGTGCCCCGCCCAGCACAAGCTCAGGACATGGAGGT
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000493230.5; ENST00000397594.5; ENST00000451590.5; ENST00000311189.8; ENST00000478324.5; ENST00000462734.1; ENST00000417302.5; ENST00000397596.6
External Link	RMBase: m6A_site_125578
mod ID: M6ASITE002974		Click to Show/Hide the Full List
mod site	chr11:532708-532709:-		[4]
Sequence	GGTGCGTGAGATCCGGCAGCACAAGCTGCGGAAGCTGAACC
Motif Score	2.830589286
Cell/Tissue List	kidney; liver; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000462734.1; ENST00000493230.5; ENST00000417302.5; ENST00000397596.6; ENST00000478324.5; ENST00000451590.5; ENST00000311189.8; ENST00000479482.1; ENST00000397594.5
External Link	RMBase: m6A_site_125579
mod ID: M6ASITE002975		Click to Show/Hide the Full List
mod site	chr11:532735-532736:-		[3]
Sequence	GGGAGTGGAGGATGCCTTCTACACGTTGGTGCGTGAGATCC
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000478324.5; ENST00000462734.1; ENST00000311189.8; ENST00000417302.5; ENST00000493230.5; ENST00000479482.1; ENST00000451590.5; ENST00000397596.6; ENST00000397594.5
External Link	RMBase: m6A_site_125580
mod ID: M6ASITE002976		Click to Show/Hide the Full List
mod site	chr11:533480-533481:-		[3]
Sequence	CCGAAGCTACGGCATCCCCTACATCGAGACCTCGGCCAAGA
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000417302.5; ENST00000397596.6; ENST00000311189.8; ENST00000479482.1; ENST00000462734.1; ENST00000451590.5; ENST00000397594.5; ENST00000478324.5; ENST00000493230.5
External Link	RMBase: m6A_site_125581
mod ID: M6ASITE002977		Click to Show/Hide the Full List
mod site	chr11:533555-533556:-		[3]
Sequence	GCCCATGGTGCTGGTGGGGAACAAGTGTGACCTGGCTGCAC
Motif Score	2.951386905
Cell/Tissue List	hESC-HEK293T; HEK293A-TOA
Seq Type List	MAZTER-seq; m6A-seq
Transcript ID List	ENST00000417302.5; ENST00000397596.6; ENST00000397594.5; ENST00000462734.1; ENST00000478324.5; ENST00000479482.1; ENST00000451590.5; ENST00000311189.8; ENST00000493230.5
External Link	RMBase: m6A_site_125582
mod ID: M6ASITE002978		Click to Show/Hide the Full List
mod site	chr11:533588-533589:-		[5]
Sequence	GCAGATCAAACGGGTGAAGGACTCGGATGACGTGCCCATGG
Motif Score	4.065041667
Cell/Tissue List	HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000451590.5; ENST00000462734.1; ENST00000493230.5; ENST00000397596.6; ENST00000311189.8; ENST00000479482.1; ENST00000417302.5; ENST00000478324.5; ENST00000397594.5
External Link	RMBase: m6A_site_125583
mod ID: M6ASITE002979		Click to Show/Hide the Full List
mod site	chr11:533780-533781:-		[5]
Sequence	CAACACCAAGTCTTTTGAGGACATCCACCAGTACAGGTGAA
Motif Score	3.643047619
Cell/Tissue List	HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000397594.5; ENST00000493230.5; ENST00000479482.1; ENST00000311189.8; ENST00000451590.5; ENST00000397596.6; ENST00000417302.5
External Link	RMBase: m6A_site_125584
mod ID: M6ASITE002980		Click to Show/Hide the Full List
mod site	chr11:533801-533802:-		[3]
Sequence	CCTGTGTGTGTTTGCCATCAACAACACCAAGTCTTTTGAGG
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000417302.5; ENST00000451590.5; ENST00000311189.8; ENST00000493230.5; ENST00000468682.2; ENST00000479482.1; ENST00000397594.5; ENST00000397596.6
External Link	RMBase: m6A_site_125585
mod ID: M6ASITE002981		Click to Show/Hide the Full List
mod site	chr11:533843-533844:-		[3]
Sequence	CAGCGCCATGCGGGACCAGTACATGCGCACCGGGGAGGGCT
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000493230.5; ENST00000468682.2; ENST00000417302.5; ENST00000397594.5; ENST00000479482.1; ENST00000451590.5; ENST00000397596.6; ENST00000311189.8
External Link	RMBase: m6A_site_125586
mod ID: M6ASITE002982		Click to Show/Hide the Full List
mod site	chr11:533849-533850:-		[5]
Sequence	GGAGTACAGCGCCATGCGGGACCAGTACATGCGCACCGGGG
Motif Score	3.622404762
Cell/Tissue List	HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000468682.2; ENST00000311189.8; ENST00000451590.5; ENST00000493230.5; ENST00000479482.1; ENST00000397594.5; ENST00000397596.6; ENST00000417302.5
External Link	RMBase: m6A_site_125587
mod ID: M6ASITE002983		Click to Show/Hide the Full List
mod site	chr11:533894-533895:-		[3]
Sequence	TGGGGAGACGTGCCTGTTGGACATCCTGGATACCGCCGGCC
Motif Score	3.643047619
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000311189.8; ENST00000468682.2; ENST00000417302.5; ENST00000479482.1; ENST00000397596.6; ENST00000451590.5; ENST00000493230.5; ENST00000397594.5
External Link	RMBase: m6A_site_125588
mod ID: M6ASITE002984		Click to Show/Hide the Full List
mod site	chr11:534245-534246:-
Sequence	GACCATCCAGCTGATCCAGAACCATTTTGTGGACGAATACG
Motif Score	2.930744048
Cell/Tissue List	HEK293T
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000397596.6; ENST00000451590.5; ENST00000311189.8; ENST00000493230.5; ENST00000417302.5; ENST00000468682.2; ENST00000397594.5
External Link	RMBase: m6A_site_125589

Ref 1	A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells. Cell. 2015 Jun 18;161(7):1668-80. doi: 10.1016/j.cell.2015.05.045.
Ref 2	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 3	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 4	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 5	The U6 snRNA m(6)A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention. Cell. 2017 May 18;169(5):824-835.e14. doi: 10.1016/j.cell.2017.05.003.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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