m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01426)

Target Name	Forkhead box protein O6 (FOXO6)
Gene Name	FOXO6
Chromosomal Location	1p34.2
Function	Transcriptional activator. Click to Show/Hide
Uniprot ID	FOXO6_HUMAN
HGNC ID	HGNC:24814

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01426)

Forkhead box protein O6 (FOXO6)

5-methylcytidine (m5C)

In total 1 m6A sequence/site(s) in this target gene
mod ID: M5CSITE001799		Click to Show/Hide the Full List
mod site	chr1:41381968-41381969:+
Sequence	GGCGGCGGGAGACCCCTGCTCGGGGAGGCGGCCGAGCTGGA
Cell/Tissue List	testis
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000641094.1; ENST00000372591.1
External Link	RMBase: m5C_site_2308

N6-methyladenosine (m6A)

In total 10 m6A sequence/site(s) in this target gene
mod ID: M6ASITE020635		Click to Show/Hide the Full List
mod site	chr1:41382514-41382515:+		[2]
Sequence	CCGCTTCCCGGCCGACCTGGACCTCGACATGTTCAGCGGGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; H1A; H1B; hESCs
Seq Type List	m6A-seq
Transcript ID List	ENST00000372591.1; ENST00000641094.1
External Link	RMBase: m6A_site_25688
mod ID: M6ASITE020636		Click to Show/Hide the Full List
mod site	chr1:41382571-41382572:+		[3]
Sequence	GGAGTCCATCATCCTCAACGACTTCATGGACAGCGACGAAA
Motif Score	3.287565476
Cell/Tissue List	A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000641094.1; ENST00000372591.1
External Link	RMBase: m6A_site_25689
mod ID: M6ASITE020637		Click to Show/Hide the Full List
mod site	chr1:41382580-41382581:+		[2]
Sequence	CATCCTCAACGACTTCATGGACAGCGACGAAATGGACTTCA
Motif Score	3.643047619
Cell/Tissue List	HeLa; H1A; H1B; hESCs; GSC-11; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000641094.1; ENST00000372591.1
External Link	RMBase: m6A_site_25690
mod ID: M6ASITE020638		Click to Show/Hide the Full List
mod site	chr1:41382595-41382596:+		[2]
Sequence	CATGGACAGCGACGAAATGGACTTCAACTTCGATTCGGCCC
Motif Score	4.065041667
Cell/Tissue List	HeLa; H1A; H1B; hESCs; GSC-11; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000372591.1; ENST00000641094.1
External Link	RMBase: m6A_site_25691
mod ID: M6ASITE094726		Click to Show/Hide the Full List
mod site	KN196472.1:132007-132008:+		[2]
Sequence	TGCGCCGTCTGCCCATGCAGACCATCCAGGAGAACAAGCAG
Motif Score	2.876744048
Cell/Tissue List	HeLa; U2OS; GSC-11; HEK293T; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000643181.1; ENST00000642843.1; ENST00000643531.1; ENST00000630406.6
External Link	RMBase: m6A_site_881763
mod ID: M6ASITE094727		Click to Show/Hide the Full List
mod site	KN196472.1:132020-132021:+		[2]
Sequence	CATGCAGACCATCCAGGAGAACAAGCAGGCCAGCTTCGTGC
Motif Score	2.951386905
Cell/Tissue List	HeLa; U2OS; GSC-11; HEK293T; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000643181.1; ENST00000630406.6; ENST00000642843.1; ENST00000643531.1
External Link	RMBase: m6A_site_881764
mod ID: M6ASITE094728		Click to Show/Hide the Full List
mod site	KN196472.1:132410-132411:+		[4]
Sequence	CCGCTTCCCGGCCGACCTGGACCTCGACATGTTCAGCGGGA
Motif Score	3.622404762
Cell/Tissue List	HEK293T; HEK293A-TOA
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000630406.6; ENST00000642843.1; ENST00000643181.1; ENST00000643531.1
External Link	RMBase: m6A_site_881765
mod ID: M6ASITE094729		Click to Show/Hide the Full List
mod site	KN196472.1:132476-132477:+		[4]
Sequence	CATCCTCAACGACTTCATGGACAGCGACGAAATGGACTTCA
Motif Score	3.643047619
Cell/Tissue List	HEK293T; HEK293A-TOA; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000642843.1; ENST00000643531.1; ENST00000643181.1; ENST00000630406.6
External Link	RMBase: m6A_site_881766
mod ID: M6ASITE094730		Click to Show/Hide the Full List
mod site	KN196472.1:132491-132492:+		[4]
Sequence	CATGGACAGCGACGAAATGGACTTCAACTTCGATTCGGCCC
Motif Score	4.065041667
Cell/Tissue List	HEK293T; HEK293A-TOA; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000643531.1; ENST00000643181.1; ENST00000642843.1; ENST00000630406.6
External Link	RMBase: m6A_site_881767
mod ID: M6ASITE094731		Click to Show/Hide the Full List
mod site	KN196472.1:132700-132701:+
Sequence	CGGCCCCAGCCCAGCTAGGGACCCCTCTCGGAGGCCGGCCG
Motif Score	3.622404762
Cell/Tissue List	HEK293T
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000643531.1; ENST00000642843.1
External Link	RMBase: m6A_site_881768

Ref 1	Synthesis and structure-activity relationship studies of N-benzyl-2-phenylpyrimidin-4-amine derivatives as potent USP1/UAF1 deubiquitinase inhibitors with anticancer activity against nonsmall cell lung cancer. J Med Chem. 2014 Oct 9;57(19):8099-110. doi: 10.1021/jm5010495. Epub 2014 Sep 17.
Ref 2	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 3	A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes Dev. 2015 Oct 1;29(19):2037-53. doi: 10.1101/gad.269415.115. Epub 2015 Sep 24.
Ref 4	The U6 snRNA m(6)A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention. Cell. 2017 May 18;169(5):824-835.e14. doi: 10.1016/j.cell.2017.05.003.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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