m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01416)

Target Name	Zinc finger and BTB domain-containing protein 7C (ZBTB7C)
Synonyms	Affected by papillomavirus DNA integration in ME180 cells protein 1; APM-1; Zinc finger and BTB domain-containing protein 36; Zinc finger protein 857C Click to Show/Hide
Gene Name	ZBTB7C
Chromosomal Location	18q21.1
Function	May be a tumor suppressor gene. Click to Show/Hide
Gene ID	201501
Uniprot ID	ZBT7C_HUMAN
HGNC ID	HGNC:31700
KEGG ID	hsa:201501

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01416)

Zinc finger and BTB domain-containing protein 7C (ZBTB7C)

Adenosine-to-Inosine editing (A-to-I)

In total 1 m6A sequence/site(s) in this target gene
mod ID: A2ISITE008619		Click to Show/Hide the Full List
mod site	chr18:48169980-48169981:-		[2]
Sequence	GAGGTGAGGGGTGGGAGAGTAGATGGAGTCAGGGAAACACA
Transcript ID List	ENST00000588053.5; ENST00000593159.5; ENST00000591526.5; ENST00000590800.6; ENST00000589194.5; ENST00000586743.5; ENST00000588566.5; ENST00000588028.1; ENST00000589077.5; ENST00000590178.5; ENST00000590855.5; ENST00000589619.5; ENST00000585404.5; ENST00000586047.5; ENST00000592656.5; ENST00000586525.5; ENST00000588970.5; ENST00000588149.5; ENST00000591279.5; ENST00000591405.5; ENST00000589170.5; ENST00000587107.5; ENST00000592387.5; ENST00000590374.5
External Link	RMBase: RNA-editing_site_63463

N6-methyladenosine (m6A)

In total 33 m6A sequence/site(s) in this target gene
mod ID: M6ASITE037060		Click to Show/Hide the Full List
mod site	chr18:48026981-48026982:-		[3]
Sequence	TTGCCTTAGTGATTCAAGGGACAATCTTCCATAACTTCGGT
Motif Score	3.643047619
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000590800.6; ENST00000535628.6; ENST00000588982.5; ENST00000586438.5
External Link	RMBase: m6A_site_400756
mod ID: M6ASITE037061		Click to Show/Hide the Full List
mod site	chr18:48027073-48027074:-		[3]
Sequence	CCCTGTCTGTCTGTGGGAGAACTTTGGAATTTTTTCTATTT
Motif Score	3.373380952
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000590800.6; ENST00000588982.5; ENST00000586438.5; ENST00000535628.6
External Link	RMBase: m6A_site_400757
mod ID: M6ASITE037062		Click to Show/Hide the Full List
mod site	chr18:48027390-48027391:-
Sequence	AGTGATTGGGGCTGAACCAGACTTTAAAAGAGAGGAAAAAA
Motif Score	3.319380952
Cell/Tissue List	HEK293T
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000535628.6; ENST00000586438.5; ENST00000590800.6; ENST00000588982.5
External Link	RMBase: m6A_site_400758
mod ID: M6ASITE037063		Click to Show/Hide the Full List
mod site	chr18:48027395-48027396:-
Sequence	AGCCAAGTGATTGGGGCTGAACCAGACTTTAAAAGAGAGGA
Motif Score	2.930744048
Cell/Tissue List	HEK293T
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000535628.6; ENST00000586438.5; ENST00000588982.5; ENST00000590800.6
External Link	RMBase: m6A_site_400759
mod ID: M6ASITE037064		Click to Show/Hide the Full List
mod site	chr18:48027477-48027478:-
Sequence	GATTCCTGTCTTCGTTTCAGACACTTTTCTCTGAAGCATGC
Motif Score	2.897386905
Cell/Tissue List	HEK293T
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000586438.5; ENST00000588982.5; ENST00000535628.6; ENST00000590800.6
External Link	RMBase: m6A_site_400760
mod ID: M6ASITE037065		Click to Show/Hide the Full List
mod site	chr18:48027598-48027599:-		[4]
Sequence	CTCACAACTCTCCAGAAGAGACCCCCTGATTCTTCACACCA
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293T; HepG2; H1A; H1B; GSC-11; HEK293A-TOA; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000586438.5; ENST00000535628.6; ENST00000588982.5; ENST00000590800.6
External Link	RMBase: m6A_site_400761
mod ID: M6ASITE037066		Click to Show/Hide the Full List
mod site	chr18:48027629-48027630:-		[5]
Sequence	AAGGCCAGAGAAGAGCACAGACTCTGTCCCTCTCACAACTC
Motif Score	3.319380952
Cell/Tissue List	HEK293T; HepG2; H1A; H1B; GSC-11; HEK293A-TOA; endometrial; GSCs
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000535628.6; ENST00000588982.5; ENST00000590800.6; ENST00000586438.5
External Link	RMBase: m6A_site_400762
mod ID: M6ASITE037067		Click to Show/Hide the Full List
mod site	chr18:48027654-48027655:-		[5]
Sequence	CCTGAGCAAAAACACAACAAACAAAAAGGCCAGAGAAGAGC
Motif Score	2.20572619
Cell/Tissue List	HEK293T; HepG2; H1A; H1B; GSC-11; HEK293A-TOA; endometrial; GSCs
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000590800.6; ENST00000586438.5; ENST00000535628.6; ENST00000588982.5
External Link	RMBase: m6A_site_400763
mod ID: M6ASITE037068		Click to Show/Hide the Full List
mod site	chr18:48027663-48027664:-		[5]
Sequence	TGGCTTTTTCCTGAGCAAAAACACAACAAACAAAAAGGCCA
Motif Score	2.20572619
Cell/Tissue List	HEK293T; HepG2; H1B; GSC-11; HEK293A-TOA; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000590800.6; ENST00000588982.5; ENST00000535628.6; ENST00000586438.5
External Link	RMBase: m6A_site_400764
mod ID: M6ASITE037069		Click to Show/Hide the Full List
mod site	chr18:48027705-48027706:-		[5]
Sequence	TGTGCTATGGGCACAAAGAGACTTCAGCTCTTCCTGTTGCC
Motif Score	3.319380952
Cell/Tissue List	HEK293T; HepG2; GSC-11; HEK293A-TOA
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000535628.6; ENST00000590800.6; ENST00000586438.5; ENST00000588982.5
External Link	RMBase: m6A_site_400765
mod ID: M6ASITE037070		Click to Show/Hide the Full List
mod site	chr18:48028973-48028974:-		[4]
Sequence	ACCGGCCCATGCCACAAAGAACTGGGTGCCCAGGGGCACTT
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000588982.5; ENST00000590800.6; ENST00000535628.6; ENST00000586438.5
External Link	RMBase: m6A_site_400766
mod ID: M6ASITE037071		Click to Show/Hide the Full List
mod site	chr18:48029459-48029460:-		[6]
Sequence	TGGAGCGGCAGTTCGAGGAGACACAGATGAAGCTGTTCGGG
Motif Score	2.897386905
Cell/Tissue List	H1B; GSC-11
Seq Type List	m6A-seq
Transcript ID List	ENST00000586438.5; ENST00000590800.6; ENST00000535628.6; ENST00000588982.5
External Link	RMBase: m6A_site_400767
mod ID: M6ASITE037072		Click to Show/Hide the Full List
mod site	chr18:48029905-48029906:-		[4]
Sequence	GTCTCTGCATTGCAGGCAGGACAAGCTGAAAATCCACATGC
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000586438.5; ENST00000535628.6; ENST00000590800.6; ENST00000588982.5
External Link	RMBase: m6A_site_400768
mod ID: M6ASITE037073		Click to Show/Hide the Full List
mod site	chr18:48040138-48040139:-		[7]
Sequence	CTGCCGGGGGGGCCTCTGGGACCCATCAAGGCGGAGAACGA
Motif Score	3.622404762
Cell/Tissue List	HEK293T; HepG2; H1B; H1A; GSC-11; HEK293A-TOA; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000590800.6; ENST00000588982.5; ENST00000586438.5; ENST00000535628.6
External Link	RMBase: m6A_site_400769
mod ID: M6ASITE037074		Click to Show/Hide the Full List
mod site	chr18:48040172-48040173:-		[4]
Sequence	CCCTAATGACTTCTTCAAGGACATGTTCCCTGACCTGCCGG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HEK293T; HepG2; H1A; H1B; GSC-11; HEK293A-TOA; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000590800.6; ENST00000535628.6; ENST00000588982.5; ENST00000586438.5
External Link	RMBase: m6A_site_400770
mod ID: M6ASITE037075		Click to Show/Hide the Full List
mod site	chr18:48040280-48040281:-		[4]
Sequence	GCTGCCTGAGCAGCCCATGGACAGTGGGCCACTGGATCTGG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HEK293T; HepG2; H1A; H1B; GSC-11; HEK293A-TOA; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000588982.5; ENST00000590800.6; ENST00000586438.5; ENST00000535628.6
External Link	RMBase: m6A_site_400771
mod ID: M6ASITE037076		Click to Show/Hide the Full List
mod site	chr18:48040319-48040320:-		[4]
Sequence	TCCACACCTCTGGCCAGGGGACTTCGGTGCCTTTGCCCAGC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T; HepG2; H1B; GSC-11; HEK293A-TOA; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000535628.6; ENST00000590800.6; ENST00000586438.5; ENST00000588982.5
External Link	RMBase: m6A_site_400772
mod ID: M6ASITE037077		Click to Show/Hide the Full List
mod site	chr18:48040346-48040347:-		[7]
Sequence	CTTGTCTCCATTCGCCCCGGACTTCTTTCCACACCTCTGGC
Motif Score	4.065041667
Cell/Tissue List	HEK293T; HepG2; H1B; GSC-11; HEK293A-TOA; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000535628.6; ENST00000588982.5; ENST00000590800.6; ENST00000586438.5
External Link	RMBase: m6A_site_400773
mod ID: M6ASITE037078		Click to Show/Hide the Full List
mod site	chr18:48040372-48040373:-		[7]
Sequence	GCCAACATCCCCGACAGGAGACCCTCCTTGTCTCCATTCGC
Motif Score	2.876744048
Cell/Tissue List	HEK293T; HepG2; H1B; GSC-11; HEK293A-TOA; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000590800.6; ENST00000588982.5; ENST00000586438.5; ENST00000535628.6
External Link	RMBase: m6A_site_400774
mod ID: M6ASITE037079		Click to Show/Hide the Full List
mod site	chr18:48040406-48040407:-		[4]
Sequence	CGAATCTCTGCTAAGGGAGAACCTGTACCCCAAGGCCAACA
Motif Score	2.930744048
Cell/Tissue List	HeLa; HEK293T; HepG2; H1B; Jurkat; GSC-11; HEK293A-TOA; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000535628.6; ENST00000588982.5; ENST00000586438.5; ENST00000590800.6
External Link	RMBase: m6A_site_400775
mod ID: M6ASITE037080		Click to Show/Hide the Full List
mod site	chr18:48040436-48040437:-		[4]
Sequence	CCATCTGGGGGTGATCCGGGACTTCTCCATCGAATCTCTGC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T; HepG2; H1B; GSC-11; HEK293A-TOA; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000590800.6; ENST00000586438.5; ENST00000535628.6; ENST00000588982.5
External Link	RMBase: m6A_site_400776
mod ID: M6ASITE037081		Click to Show/Hide the Full List
mod site	chr18:48040490-48040491:-		[4]
Sequence	CTATTCAGACACCCCCAGGGACTTCCCTGACTCCTTCCAGG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T; HepG2; H1B; GSC-11; HEK293A-TOA; endometrial; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000588982.5; ENST00000590800.6; ENST00000586438.5; ENST00000535628.6
External Link	RMBase: m6A_site_400777
mod ID: M6ASITE037082		Click to Show/Hide the Full List
mod site	chr18:48040502-48040503:-		[4]
Sequence	CACAGAGAAGGCCTATTCAGACACCCCCAGGGACTTCCCTG
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; HepG2; H1B; GSC-11; HEK293A-TOA; endometrial; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000590800.6; ENST00000586438.5; ENST00000535628.6; ENST00000588982.5
External Link	RMBase: m6A_site_400778
mod ID: M6ASITE037083		Click to Show/Hide the Full List
mod site	chr18:48040533-48040534:-		[4]
Sequence	GCCACCAAAGCCCTTCCAAGACAGACCATCTCACAGAGAAG
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; HepG2; H1A; H1B; GSC-11; HEK293A-TOA; endometrial; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000535628.6; ENST00000586438.5; ENST00000590800.6; ENST00000588982.5
External Link	RMBase: m6A_site_400779
mod ID: M6ASITE037084		Click to Show/Hide the Full List
mod site	chr18:48040562-48040563:-		[4]
Sequence	AAACTTGCCTGACCCCCAGGACATCAGCTGCCACCAAAGCC
Motif Score	3.643047619
Cell/Tissue List	HeLa; HEK293T; HepG2; H1A; H1B; GSC-11; HEK293A-TOA; endometrial; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000590800.6; ENST00000588982.5; ENST00000586438.5; ENST00000535628.6
External Link	RMBase: m6A_site_400780
mod ID: M6ASITE037085		Click to Show/Hide the Full List
mod site	chr18:48040580-48040581:-		[4]
Sequence	GGACTTTGCTGACCAAGAAAACTTGCCTGACCCCCAGGACA
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T; HepG2; H1A; H1B; GSC-11; HEK293A-TOA; endometrial; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000588982.5; ENST00000586438.5; ENST00000535628.6; ENST00000590800.6
External Link	RMBase: m6A_site_400781
mod ID: M6ASITE037086		Click to Show/Hide the Full List
mod site	chr18:48040598-48040599:-		[4]
Sequence	TGACGATGATGACACGGAGGACTTTGCTGACCAAGAAAACT
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; H1A; H1B; GSC-11; HEK293A-TOA; endometrial; GSCs
Seq Type List	m6A-seq
Transcript ID List	ENST00000535628.6; ENST00000586438.5; ENST00000590800.6; ENST00000588982.5
External Link	RMBase: m6A_site_400782
mod ID: M6ASITE037087		Click to Show/Hide the Full List
mod site	chr18:48040968-48040969:-		[4]
Sequence	TGCAGGAGCAGGAGTATCGGACCCACCGCTCCGTCCTGGCT
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000590800.6; ENST00000586438.5; ENST00000590437.5; ENST00000535628.6; ENST00000588982.5
External Link	RMBase: m6A_site_400783
mod ID: M6ASITE037088		Click to Show/Hide the Full List
mod site	chr18:48041108-48041109:-		[4]
Sequence	CTGCAGGGCTCTGGCTGAGAACATGGCCAATGACATTGATG
Motif Score	2.951386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000592656.5; ENST00000585404.5; ENST00000589194.5; ENST00000590800.6; ENST00000535628.6; ENST00000588149.5; ENST00000586525.5; ENST00000591405.5; ENST00000590374.5; ENST00000592387.5; ENST00000589170.5; ENST00000587107.5; ENST00000586743.5; ENST00000586438.5; ENST00000591526.5; ENST00000590178.5; ENST00000591279.5; ENST00000588970.5; ENST00000590855.5; ENST00000593159.5; ENST00000588982.5; ENST00000586047.5; ENST00000589077.5; ENST00000589619.5; ENST00000588053.5; ENST00000588566.5; ENST00000588028.1; ENST00000590437.5
External Link	RMBase: m6A_site_400784
mod ID: M6ASITE037089		Click to Show/Hide the Full List
mod site	chr18:48072493-48072494:-		[4]
Sequence	GGCCCTCCTTCAGGAGTGGGACATGGGAAGGAGGCTGCAGA
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000588028.1; ENST00000585404.5; ENST00000588982.5; ENST00000586438.5; ENST00000588053.5; ENST00000589194.5; ENST00000588149.5; ENST00000590437.5; ENST00000591405.5; ENST00000589619.5; ENST00000593159.5; ENST00000587107.5; ENST00000591526.5; ENST00000586525.5; ENST00000589170.5; ENST00000592656.5; ENST00000590855.5; ENST00000591279.5; ENST00000586743.5; ENST00000588970.5; ENST00000590374.5; ENST00000588566.5; ENST00000535628.6; ENST00000586047.5; ENST00000590178.5; ENST00000590800.6; ENST00000592387.5; ENST00000589077.5
External Link	RMBase: m6A_site_400785
mod ID: M6ASITE037090		Click to Show/Hide the Full List
mod site	chr18:48409277-48409278:-		[8]
Sequence	CGGCGAAGGAGGACGCCAGGACTGCGTCCCGGAGCCAAGTG
Motif Score	4.065041667
Cell/Tissue List	GSC-11
Seq Type List	m6A-seq
Transcript ID List	ENST00000591279.5; ENST00000592387.5; ENST00000587107.5; ENST00000586525.5; ENST00000590800.6; ENST00000588970.5; ENST00000589194.5; ENST00000588149.5; ENST00000590855.5
External Link	RMBase: m6A_site_400786
mod ID: M6ASITE037091		Click to Show/Hide the Full List
mod site	chr18:48409304-48409305:-		[8]
Sequence	GGGCGCGCAGGGACCGGCGGACACCGGCGGCGAAGGAGGAC
Motif Score	3.643047619
Cell/Tissue List	GSC-11
Seq Type List	m6A-seq
Transcript ID List	ENST00000590800.6; ENST00000588149.5
External Link	RMBase: m6A_site_400787
mod ID: M6ASITE037092		Click to Show/Hide the Full List
mod site	chr18:48409312-48409313:-		[8]
Sequence	CGAGGCTCGGGCGCGCAGGGACCGGCGGACACCGGCGGCGA
Motif Score	3.622404762
Cell/Tissue List	GSC-11
Seq Type List	m6A-seq
Transcript ID List	ENST00000588149.5; ENST00000590800.6
External Link	RMBase: m6A_site_400788

Ref 1	National Cancer Institute Drug Dictionary (drug id 740856).
Ref 2	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 3	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.
Ref 4	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 5	Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq. Nature. 2012 Apr 29;485(7397):201-6. doi: 10.1038/nature11112.
Ref 6	m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells. Cell Stem Cell. 2014 Dec 4;15(6):707-19. doi: 10.1016/j.stem.2014.09.019. Epub 2014 Oct 16.
Ref 7	Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons. Cell. 2012 Jun 22;149(7):1635-46. doi: 10.1016/j.cell.2012.05.003. Epub 2012 May 17.
Ref 8	m(6)A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program. Cancer Cell. 2017 Apr 10;31(4):591-606.e6. doi: 10.1016/j.ccell.2017.02.013. Epub 2017 Mar 23.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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