m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01349)

Target Name	Protein MROH8 (MROH8)
Synonyms	Maestro heat-like repeat-containing protein family member 8 Click to Show/Hide
Gene Name	MROH8
Chromosomal Location	20q11.23
Gene ID	140699
Uniprot ID	MROH8_HUMAN
HGNC ID	HGNC:16125
KEGG ID	hsa:140699

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01349)

Protein MROH8 (MROH8)

Adenosine-to-Inosine editing (A-to-I)

In total 7 m6A sequence/site(s) in this target gene
mod ID: A2ISITE010529		Click to Show/Hide the Full List
mod site	chr20:37119423-37119424:-		[2]
Sequence	CCAGGCTGGAGTTCAGTGACACCATCGCTGCGTGCCGCAGC
Transcript ID List	ENST00000343811.8; ENST00000400441.7; ENST00000417458.5
External Link	RMBase: RNA-editing_site_87194
mod ID: A2ISITE010530		Click to Show/Hide the Full List
mod site	chr20:37130334-37130335:-		[2]
Sequence	CGCTTGAGCCTAGGAGTTCAAGACCAGCCTGGGCAACATGG
Transcript ID List	ENST00000400440.6; rmsk_5112767; ENST00000400441.7; ENST00000343811.8; ENST00000417458.5; ENST00000421643.1
External Link	RMBase: RNA-editing_site_87195
mod ID: A2ISITE010531		Click to Show/Hide the Full List
mod site	chr20:37132472-37132473:-		[3]
Sequence	TTGTGGTGGCACACGCCTATAGTTCCAAATACTCAGGAGGC
Transcript ID List	ENST00000400440.6; ENST00000343811.8; ENST00000421643.1; ENST00000400441.7; rmsk_5112773; ENST00000417458.5
External Link	RMBase: RNA-editing_site_87196
mod ID: A2ISITE010532		Click to Show/Hide the Full List
mod site	chr20:37132474-37132475:-		[3]
Sequence	AGTTGTGGTGGCACACGCCTATAGTTCCAAATACTCAGGAG
Transcript ID List	ENST00000421643.1; ENST00000400441.7; ENST00000343811.8; rmsk_5112773; ENST00000417458.5; ENST00000400440.6
External Link	RMBase: RNA-editing_site_87197
mod ID: A2ISITE010533		Click to Show/Hide the Full List
mod site	chr20:37146090-37146091:-		[2]
Sequence	CCTCCTAAAGTGCAGGGACTACAGGTGTCCACCACCGTACC
Transcript ID List	ENST00000417458.5; ENST00000400440.6; ENST00000421643.1; ENST00000343811.8; ENST00000400441.7
External Link	RMBase: RNA-editing_site_87198
mod ID: A2ISITE010534		Click to Show/Hide the Full List
mod site	chr20:37175067-37175068:-		[2]
Sequence	ATCTATGCTAAACATTCAGTAAATAGAGACCTGCTCAATCA
Transcript ID List	ENST00000400440.6; ENST00000422138.1; ENST00000400441.7; ENST00000434295.5; ENST00000421643.1; ENST00000343811.8
External Link	RMBase: RNA-editing_site_87199
mod ID: A2ISITE010535		Click to Show/Hide the Full List
mod site	chr20:37175749-37175750:-		[2]
Sequence	GTCTTAAACTCCTGGGCTTAAGGGATCATCTTGCCTCAGCC
Transcript ID List	ENST00000400441.7; ENST00000343811.8; ENST00000422138.1; ENST00000421643.1; ENST00000400440.6; ENST00000434295.5
External Link	RMBase: RNA-editing_site_87200

5-methylcytidine (m5C)

In total 3 m6A sequence/site(s) in this target gene
mod ID: M5CSITE002680		Click to Show/Hide the Full List
mod site	chr20:37137922-37137923:-		[4]
Sequence	GCCCAGTTATCCATAATCAGCCAGCCTAGAGTCCGCCAACA
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000400441.7; ENST00000343811.8; ENST00000400440.6; ENST00000421643.1; ENST00000417458.5
External Link	RMBase: m5C_site_28924
mod ID: M5CSITE002681		Click to Show/Hide the Full List
mod site	chr20:37147845-37147846:-		[4]
Sequence	TGGCACTGCTCTGTGGGGACCCACAGGAAAAGGTGGCTGAG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000400441.7; ENST00000421643.1; ENST00000400440.6; ENST00000343811.8; ENST00000417458.5
External Link	RMBase: m5C_site_28925
mod ID: M5CSITE002682		Click to Show/Hide the Full List
mod site	chr20:37155080-37155081:-		[4]
Sequence	CAAGTTCTGAAGTGCCTATCCAAACATCTCAACTTGAAGGT
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000343811.8; ENST00000400440.6; ENST00000421643.1; ENST00000400441.7; ENST00000417458.5
External Link	RMBase: m5C_site_28926

N6-methyladenosine (m6A)

In total 2 m6A sequence/site(s) in this target gene
mod ID: M6ASITE052529		Click to Show/Hide the Full List
mod site	chr20:37178942-37178943:-		[5]
Sequence	GCCCGGCCCATTTTAAAGGAACAGGAAGGGTCTCGTCGGGA
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; A549; Jurkat; peripheral-blood; GSC-11; HEK293T; iSLK; MSC; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000421643.1; ENST00000434295.5; ENST00000343811.8; ENST00000400441.7; ENST00000400440.6; ENST00000422138.1
External Link	RMBase: m6A_site_530614
mod ID: M6ASITE052532		Click to Show/Hide the Full List
mod site	chr20:37179264-37179265:-		[5]
Sequence	CGCCACAGGGGACGCCAGGGACTCGCGGCAGGCTCTGCGGG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; A549; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; TREX; iSLK; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000400440.6; ENST00000421643.1; ENST00000434295.5; ENST00000400441.7; ENST00000343811.8
External Link	RMBase: m6A_site_530617

Ref 1	Active efflux of the 5-HT(1A) receptor agonist flesinoxan via P-glycoprotein at the blood-brain barrier. Eur J Pharm Sci. 2001 Aug;14(1):81-6.
Ref 2	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 3	Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome. Nat Biotechnol. 2012 Feb 12;30(3):253-60. doi: 10.1038/nbt.2122.
Ref 4	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 5	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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