General Information of the m6A Target Gene (ID: M6ATAR01345)
Target Name Cathepsin K (CTSK)
Synonyms
EC 3.4.22.38; Cathepsin O; Cathepsin O2; Cathepsin X
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Gene Name Ctsk
Chromosomal Location 1q21.3
Family Peptidase C1 family
Function
Thiol protease involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation. Involved in the release of thyroid hormone thyroxine (T4) by limited proteolysis of TG/thyroglobulin in the thyroid follicle lumen (PubMed:11082042).
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Gene ID 1513
Uniprot ID
CATK_HUMAN
HGNC ID
HGNC:2536
KEGG ID
hsa:1513
References
Ref 1 Amino Acid Transporter ATB0,+ as a delivery system for drugs and prodrugs. Curr Drug Targets Immune Endocr Metabol Disord. 2005 Dec;5(4):357-64. doi: 10.2174/156800805774912953.