General Information of the m6A Target Gene (ID: M6ATAR01065)
Target Name NADPH oxidase 2 (NOX2)
Synonyms
EC 1.6.3.-; CGD91-phox; Cytochrome b(558; Cytochrome b558 subunit beta; Cytochrome b-245 heavy chain; Heme-binding membrane glycoprotein gp91phox; Neutrophil cytochrome b 91 kDa polypeptide; Superoxide-generating NADPH oxidase heavy chain subunit; gp91-1; gp91-phox; p22 phagocyte B-cytochrome
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Gene Name NOX2
Chromosomal Location Xp21.1-p11.4
Function
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. It is the terminal component of a respiratory chain that transfers single electrons from cytoplasmic NADPH across the plasma membrane to molecular oxygen on the exterior. Also functions as a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes. It participates in the regulation of cellular pH and is blocked by zinc.
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Gene ID 1536
Uniprot ID
CY24B_HUMAN
HGNC ID
HGNC:2578
KEGG ID
hsa:1536
RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01065)
NADPH oxidase 2 (NOX2)
N6-methyladenosine (m6A)
In total 11 m6A sequence/site(s) in this target gene
mod ID: M6ASITE090798 Click to Show/Hide the Full List
mod site chrX:37782173-37782174:+ [2]
Sequence AAGTTCTTTTACACAAGAAAACTTCTTGGGGTAAGTATAAA
Motif Score 2.627720238
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000378588.4; ENST00000465127.1
External Link RMBase: m6A_site_855794
mod ID: M6ASITE090799 Click to Show/Hide the Full List
mod site chrX:37806477-37806478:+ [2]
Sequence GAGCCAGATGCAGGAAAGGAACAATGCCGGCTTCCTCAGCT
Motif Score 2.951386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000465127.1; ENST00000378588.4
External Link RMBase: m6A_site_855795
mod ID: M6ASITE090800 Click to Show/Hide the Full List
mod site chrX:37809622-37809623:+ [2]
Sequence GATGTGATCACAGGCCTGAAACAAAAGACTTTGTATGGACG
Motif Score 2.20572619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000465127.1; ENST00000378588.4
External Link RMBase: m6A_site_855796
mod ID: M6ASITE090801 Click to Show/Hide the Full List
mod site chrX:37809629-37809630:+ [2]
Sequence TCACAGGCCTGAAACAAAAGACTTTGTATGGACGGCCCAAC
Motif Score 3.319380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000378588.4; ENST00000465127.1
External Link RMBase: m6A_site_855797
mod ID: M6ASITE090802 Click to Show/Hide the Full List
mod site chrX:37809668-37809669:+ [2]
Sequence ACTGGGATAATGAATTCAAGACAATTGCAAGTCAACACCCT
Motif Score 2.897386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000378588.4; ENST00000465127.1
External Link RMBase: m6A_site_855798
mod ID: M6ASITE090803 Click to Show/Hide the Full List
mod site chrX:37810817-37810818:+ [2]
Sequence ATAGGAGTTTTCCTCTGTGGACCTGAAGCCTTGGCTGAAAC
Motif Score 3.622404762
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000378588.4; ENST00000465127.1; rmsk_2976765
External Link RMBase: m6A_site_855799
mod ID: M6ASITE090805 Click to Show/Hide the Full List
mod site chrX:37810836-37810837:+ [2]
Sequence GACCTGAAGCCTTGGCTGAAACCCTGAGTAAACAAAGCATC
Motif Score 2.185083333
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List rmsk_2976765; ENST00000465127.1; ENST00000378588.4
External Link RMBase: m6A_site_855800
mod ID: M6ASITE090806 Click to Show/Hide the Full List
mod site chrX:37810847-37810848:+ [2]
Sequence TTGGCTGAAACCCTGAGTAAACAAAGCATCTCCAACTCTGA
Motif Score 2.20572619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000378588.4; rmsk_2976765; ENST00000465127.1
External Link RMBase: m6A_site_855801
mod ID: M6ASITE090807 Click to Show/Hide the Full List
mod site chrX:37810909-37810910:+ [2]
Sequence TTTCATTTTCAACAAGGAAAACTTCTAACTTGTCTCTTCCA
Motif Score 2.627720238
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000378588.4; ENST00000465127.1
External Link RMBase: m6A_site_855802
mod ID: M6ASITE090808 Click to Show/Hide the Full List
mod site chrX:37812335-37812336:+ [2]
Sequence TGGAGCCACAAATGTTTAGAACTCTTCAACTTCGGTAATGA
Motif Score 3.373380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000378588.4; ENST00000465127.1
External Link RMBase: m6A_site_855803
mod ID: M6ASITE090809 Click to Show/Hide the Full List
mod site chrX:37812391-37812392:+ [2]
Sequence AGCTGGGGGAAGGGCAGAAGACTGGTTTAGGAGGAAAAGGA
Motif Score 3.319380952
Cell/Tissue List HeLa; LCLs
Seq Type List m6A-seq
Transcript ID List ENST00000465127.1; ENST00000378588.4
External Link RMBase: m6A_site_855804