m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01038)

Target Name	Translation machinery-associated protein 7 (TMA7)
Synonyms	Coiled-coil domain-containing protein 72 Click to Show/Hide
Gene Name	TMA7
Chromosomal Location	3p21.31
Family	TMA7 family
Gene ID	51372
Uniprot ID	TMA7_HUMAN
HGNC ID	HGNC:26932
KEGG ID	hsa:51372

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01038)

Translation machinery-associated protein 7 (TMA7)

5-methylcytidine (m5C)

In total 4 m6A sequence/site(s) in this target gene
mod ID: M5CSITE003082		Click to Show/Hide the Full List
mod site	chr3:48443171-48443172:+
Sequence	AATCACTTGAACCTGGGAGGCGGAGGCTGCAGTGAGCCAAA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000438607.2; ENST00000477624.1; rmsk_957228
External Link	RMBase: m5C_site_32024
mod ID: M5CSITE003083		Click to Show/Hide the Full List
mod site	chr3:48443177-48443178:+
Sequence	TTGAACCTGGGAGGCGGAGGCTGCAGTGAGCCAAAATTGCA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	rmsk_957228; ENST00000477624.1; ENST00000438607.2
External Link	RMBase: m5C_site_32025
mod ID: M5CSITE003084		Click to Show/Hide the Full List
mod site	chr3:48443180-48443181:+
Sequence	AACCTGGGAGGCGGAGGCTGCAGTGAGCCAAAATTGCACCA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	rmsk_957228; ENST00000438607.2; ENST00000477624.1
External Link	RMBase: m5C_site_32026
mod ID: M5CSITE003085		Click to Show/Hide the Full List
mod site	chr3:48443505-48443506:+
Sequence	ATCGTGCCACTGCACTGCAGCCTGGGCGACAGAGCAAGATT
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000477624.1; ENST00000438607.2; rmsk_957229
External Link	RMBase: m5C_site_32027

N6-methyladenosine (m6A)

In total 16 m6A sequence/site(s) in this target gene
mod ID: M6ASITE060970		Click to Show/Hide the Full List
mod site	chr3:48440326-48440327:+		[2]
Sequence	GCGAAGGTAAGTGTTCCGGAACCGTGAGGACTGCGGGGACG
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; H1A; H1B; HEK293T; fibroblasts; A549; MT4; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000438607.2; ENST00000477624.1; ENST00000479126.1
External Link	RMBase: m6A_site_588522
mod ID: M6ASITE060971		Click to Show/Hide the Full List
mod site	chr3:48440335-48440336:+		[2]
Sequence	AGTGTTCCGGAACCGTGAGGACTGCGGGGACGGCGGGGTGG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; H1A; H1B; HEK293T; fibroblasts; A549; MT4; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000438607.2; ENST00000477624.1; ENST00000479126.1
External Link	RMBase: m6A_site_588523
mod ID: M6ASITE060972		Click to Show/Hide the Full List
mod site	chr3:48440358-48440359:+		[2]
Sequence	GCGGGGACGGCGGGGTGGGGACCGGGCGGCAGGGGCAGGCC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; A549; H1A; H1B; HEK293T; fibroblasts; LCLs; MT4; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000438607.2; ENST00000477624.1; ENST00000479126.1
External Link	RMBase: m6A_site_588524
mod ID: M6ASITE060973		Click to Show/Hide the Full List
mod site	chr3:48440424-48440425:+		[2]
Sequence	GGCAAGAAGAAGCCACTGAAACAGCCCAAGAAGCAGGCCAA
Motif Score	2.20572619
Cell/Tissue List	HeLa; HepG2; A549; H1A; H1B; hNPCs; HEK293T; fibroblasts; LCLs; MT4; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000477624.1; ENST00000479126.1; ENST00000438607.2
External Link	RMBase: m6A_site_588525
mod ID: M6ASITE060974		Click to Show/Hide the Full List
mod site	chr3:48440504-48440505:+		[2]
Sequence	GGGTGCGGGGGCGCTGGGAGACAGGCCTGAGTTGAACACGC
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; A549; H1A; H1B; hNPCs; hESCs; HEK293T; fibroblasts; LCLs; MT4; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000479126.1; ENST00000477624.1; ENST00000438607.2
External Link	RMBase: m6A_site_588526
mod ID: M6ASITE060975		Click to Show/Hide the Full List
mod site	chr3:48440519-48440520:+		[2]
Sequence	GGGAGACAGGCCTGAGTTGAACACGCTCTGCCTCTCCCCAG
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; A549; H1A; H1B; hNPCs; hESCs; HEK293T; fibroblasts; LCLs; MT4; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000479126.1; ENST00000438607.2; ENST00000477624.1
External Link	RMBase: m6A_site_588527
mod ID: M6ASITE060976		Click to Show/Hide the Full List
mod site	chr3:48440563-48440564:+		[2]
Sequence	GATAAGGCTTTCAAGCAGAAACAAAAAGAGGAGCAGAAGAA
Motif Score	2.20572619
Cell/Tissue List	HeLa; HepG2; A549; hESC-HEK293T; H1A; H1B; hNPCs; hESCs; fibroblasts; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; endometrial; NB4
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000479126.1; ENST00000477624.1; ENST00000438607.2
External Link	RMBase: m6A_site_588528
mod ID: M6ASITE060977		Click to Show/Hide the Full List
mod site	chr3:48440584-48440585:+		[2]
Sequence	CAAAAAGAGGAGCAGAAGAAACTCGAGGAGCTAAAAGCGAA
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; A549; H1A; H1B; hNPCs; hESCs; HEK293T; fibroblasts; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; endometrial; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000477624.1; ENST00000479126.1; ENST00000438607.2
External Link	RMBase: m6A_site_588529
mod ID: M6ASITE060978		Click to Show/Hide the Full List
mod site	chr3:48440720-48440721:+		[2]
Sequence	GTCTTTTTCCTGCCTCCTGAACTGCGAGGTCTCGTTTTCCG
Motif Score	3.373380952
Cell/Tissue List	HeLa; LCLs; A549; H1299; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000479126.1; ENST00000438607.2; ENST00000477624.1
External Link	RMBase: m6A_site_588531
mod ID: M6ASITE060979		Click to Show/Hide the Full List
mod site	chr3:48443955-48443956:+		[3]
Sequence	CCTCTCTATTCCCTGCCATAACATCTTTTGCCACGTATAGC
Motif Score	2.168095238
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000438607.2; ENST00000477624.1
External Link	RMBase: m6A_site_588535
mod ID: M6ASITE060980		Click to Show/Hide the Full List
mod site	chr3:48444006-48444007:+		[4]
Sequence	TGTTGTCTTGGAGCTGTTGTACATTTAAGAATAAACTTTTG
Motif Score	2.856142857
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000477624.1; ENST00000438607.2
External Link	RMBase: m6A_site_588536
mod ID: M6ASITE060981		Click to Show/Hide the Full List
mod site	chr3:48444020-48444021:+		[4]
Sequence	TGTTGTACATTTAAGAATAAACTTTTGTAAAAAAAGAAAAA
Motif Score	2.627720238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000438607.2; ENST00000477624.1
External Link	RMBase: m6A_site_588537
mod ID: M6ASITE060982		Click to Show/Hide the Full List
mod site	chr3:48444045-48444046:+		[4]
Sequence	TGTAAAAAAAGAAAAATCTTACAGTGGCTCATCATCTCTTT
Motif Score	2.07285119
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000477624.1; ENST00000438607.2
External Link	RMBase: m6A_site_588538
mod ID: M6ASITE060983		Click to Show/Hide the Full List
mod site	chr3:48444115-48444116:+		[2]
Sequence	AACTGTGAATTTAAAGTAAAACCAGCTCAGAATCTTGCCAG
Motif Score	2.185083333
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000438607.2; ENST00000477624.1
External Link	RMBase: m6A_site_588539
mod ID: M6ASITE060984		Click to Show/Hide the Full List
mod site	chr3:48444167-48444168:+		[2]
Sequence	TGGTCCTTGTTCTACCCTAAACTTTGTATCACCTGAAATTA
Motif Score	2.627720238
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000477624.1; ENST00000438607.2
External Link	RMBase: m6A_site_588540
mod ID: M6ASITE060985		Click to Show/Hide the Full List
mod site	chr3:48444189-48444190:+		[2]
Sequence	TTTGTATCACCTGAAATTAAACCAACTCATTTGAAAGGATG
Motif Score	2.185083333
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000477624.1; ENST00000438607.2
External Link	RMBase: m6A_site_588541

N7-methylguanosine (m7G)

In total 1 m6A sequence/site(s) in this target gene
mod ID: m7GSITE000099		Click to Show/Hide the Full List
mod site	chr3:48440405-48440406:+		[5]
Sequence	GCTCGTGTCGCCCACAGGTGGCAAGAAGAAGCCACTGAAAC
Cell/Tissue List	A549; HeLa; HepG2
Seq Type List	BoRed-seq&m7G-RIP-seq; m7G-seq
Transcript ID List	ENST00000477624.1; ENST00000438607.2; ENST00000479126.1
External Link	RMBase: m7G_site_646

Ref 1	Cytochrome P450 isoforms catalyze formation of catechol estrogen quinones that react with DNA. Metabolism. 2007 Jul;56(7):887-94. doi: 10.1016/j.metabol.2007.03.001.
Ref 2	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 3	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 4	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 5	METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation. Mol Cell. 2019 Jun 20;74(6):1278-1290.e9. doi: 10.1016/j.molcel.2019.03.040. Epub 2019 Apr 25.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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