m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01007)
Target Name Complement C1q subcomponent subunit A (C1QA)
Gene Name C1qA
Chromosomal Location 1p36.12
Function
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
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Gene ID 712
Uniprot ID
C1QA_HUMAN
HGNC ID
HGNC:1241
KEGG ID
hsa:712
References
Ref 1 Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance. Clin Pharmacol Ther. 2006 Dec;80(6):565-81. doi: 10.1016/j.clpt.2006.09.003.