m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00999)
Target Name Atrial natriuretic peptide-converting enzyme (CORIN)
Synonyms
EC 3.4.21.-; Corin; Heart-specific serine proteinase ATC2; Pro-ANP-converting enzyme; Transmembrane protease serine 10
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Gene Name CORIN
Chromosomal Location 4p12
Family Peptidase S1 family
Function
Serine-type endopeptidase involved in atrial natriuretic peptide (NPPA) and brain natriuretic peptide (NPPB) processing (PubMed:10880574, PubMed:21288900, PubMed:20489134, PubMed:21763278). Converts through proteolytic cleavage the non-functional propeptides NPPA and NPPB into their active hormones, ANP and BNP(1-32) respectively, thereby regulating blood pressure in the heart and promoting natriuresis, diuresis and vasodilation (PubMed:10880574, PubMed:21288900, PubMed:20489134, PubMed:21763278). Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus (PubMed:22437503). Also acts as a regulator of sodium reabsorption in kidney (By similarity).
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Gene ID 10699
Uniprot ID
CORIN_HUMAN
HGNC ID
HGNC:19012
KEGG ID
hsa:10699
RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00999)
Atrial natriuretic peptide-converting enzyme (CORIN)
Adenosine-to-Inosine editing (A-to-I)
In total 10 m6A sequence/site(s) in this target gene
mod ID: A2ISITE000336 Click to Show/Hide the Full List
mod site chr4:47680784-47680785:- [2]
Sequence CACTCCAGCCTGGGAGAAAGAGAGAGACCTTGTCTCAAAAA
Transcript ID List ENST00000504584.1; rmsk_1306642; ENST00000508498.5; ENST00000502252.5; ENST00000610355.4; ENST00000503821.5; ENST00000505909.5; ENST00000273857.9; ENST00000502726.5
External Link RMBase: RNA-editing_site_104443
mod ID: A2ISITE000337 Click to Show/Hide the Full List
mod site chr4:47680786-47680787:- [2]
Sequence TGCACTCCAGCCTGGGAGAAAGAGAGAGACCTTGTCTCAAA
Transcript ID List ENST00000502726.5; ENST00000610355.4; ENST00000508498.5; ENST00000505909.5; ENST00000273857.9; ENST00000503821.5; rmsk_1306642; ENST00000502252.5; ENST00000504584.1
External Link RMBase: RNA-editing_site_104444
mod ID: A2ISITE000338 Click to Show/Hide the Full List
mod site chr4:47680787-47680788:- [2]
Sequence CTGCACTCCAGCCTGGGAGAAAGAGAGAGACCTTGTCTCAA
Transcript ID List ENST00000502726.5; ENST00000505909.5; ENST00000273857.9; ENST00000610355.4; ENST00000504584.1; ENST00000502252.5; rmsk_1306642; ENST00000508498.5; ENST00000503821.5
External Link RMBase: RNA-editing_site_104445
mod ID: A2ISITE000339 Click to Show/Hide the Full List
mod site chr4:47680811-47680812:- [2]
Sequence CTGCAGTGAGCTATGATCACACCACTGCACTCCAGCCTGGG
Transcript ID List ENST00000508498.5; ENST00000502252.5; ENST00000610355.4; ENST00000505909.5; ENST00000504584.1; ENST00000503821.5; ENST00000273857.9; ENST00000502726.5; rmsk_1306642
External Link RMBase: RNA-editing_site_104446
mod ID: A2ISITE000340 Click to Show/Hide the Full List
mod site chr4:47680843-47680844:- [2]
Sequence TGGGAGGATCACCTGATCCTAGGAGGTTGAGGCTGCAGTGA
Transcript ID List ENST00000504584.1; ENST00000502726.5; ENST00000505909.5; rmsk_1306642; ENST00000502252.5; ENST00000503821.5; ENST00000273857.9; ENST00000508498.5; ENST00000610355.4
External Link RMBase: RNA-editing_site_104447
mod ID: A2ISITE000341 Click to Show/Hide the Full List
mod site chr4:47680848-47680849:- [2]
Sequence TGGGGTGGGAGGATCACCTGATCCTAGGAGGTTGAGGCTGC
Transcript ID List rmsk_1306642; ENST00000504584.1; ENST00000503821.5; ENST00000502252.5; ENST00000502726.5; ENST00000508498.5; ENST00000273857.9; ENST00000505909.5; ENST00000610355.4
External Link RMBase: RNA-editing_site_104448
mod ID: A2ISITE000342 Click to Show/Hide the Full List
mod site chr4:47680853-47680854:- [2]
Sequence GAGGCTGGGGTGGGAGGATCACCTGATCCTAGGAGGTTGAG
Transcript ID List ENST00000273857.9; ENST00000504584.1; ENST00000508498.5; ENST00000505909.5; ENST00000502252.5; ENST00000610355.4; rmsk_1306642; ENST00000502726.5; ENST00000503821.5
External Link RMBase: RNA-editing_site_104449
mod ID: A2ISITE000343 Click to Show/Hide the Full List
mod site chr4:47682358-47682359:- [2]
Sequence ATCTCCGCCTCCCGGGCTCAAGTGATTCTCCTGCCTCAGCC
Transcript ID List ENST00000505909.5; ENST00000504584.1; ENST00000508498.5; ENST00000503821.5; ENST00000610355.4; ENST00000502252.5; ENST00000502726.5; ENST00000273857.9
External Link RMBase: RNA-editing_site_104450
mod ID: A2ISITE000344 Click to Show/Hide the Full List
mod site chr4:47682359-47682360:- [2]
Sequence AATCTCCGCCTCCCGGGCTCAAGTGATTCTCCTGCCTCAGC
Transcript ID List ENST00000610355.4; ENST00000502726.5; ENST00000508498.5; ENST00000502252.5; ENST00000273857.9; ENST00000505909.5; ENST00000503821.5; ENST00000504584.1
External Link RMBase: RNA-editing_site_104451
mod ID: A2ISITE000345 Click to Show/Hide the Full List
mod site chr4:47682378-47682379:- [2]
Sequence CGCTATCCCGGCTCACTGCAATCTCCGCCTCCCGGGCTCAA
Transcript ID List ENST00000502252.5; ENST00000502726.5; ENST00000504584.1; ENST00000508498.5; ENST00000505909.5; ENST00000610355.4; ENST00000503821.5; ENST00000273857.9
External Link RMBase: RNA-editing_site_104452
N6-methyladenosine (m6A)
In total 19 m6A sequence/site(s) in this target gene
mod ID: M6ASITE065676 Click to Show/Hide the Full List
mod site chr4:47595358-47595359:- [3]
Sequence TTATCCTATCACAAAAAAAGACATAGATATTTAGGCTGATT
Motif Score 2.897386905
Cell/Tissue List iSLK; TREX
Seq Type List MeRIP-seq
Transcript ID List ENST00000273857.9; ENST00000610355.4
External Link RMBase: m6A_site_636757
mod ID: M6ASITE065677 Click to Show/Hide the Full List
mod site chr4:47595483-47595484:- [3]
Sequence TACAAAAGCAAACAAAGCAGACTTTGTCCTTTTGCCAGGCC
Motif Score 3.319380952
Cell/Tissue List iSLK; TREX
Seq Type List MeRIP-seq
Transcript ID List ENST00000273857.9; ENST00000610355.4; ENST00000508498.5
External Link RMBase: m6A_site_636758
mod ID: M6ASITE065678 Click to Show/Hide the Full List
mod site chr4:47595492-47595493:- [3]
Sequence GAAAGACTTTACAAAAGCAAACAAAGCAGACTTTGTCCTTT
Motif Score 2.20572619
Cell/Tissue List iSLK; TREX
Seq Type List MeRIP-seq
Transcript ID List ENST00000610355.4; ENST00000508498.5; ENST00000273857.9
External Link RMBase: m6A_site_636759
mod ID: M6ASITE065679 Click to Show/Hide the Full List
mod site chr4:47595507-47595508:- [3]
Sequence TATTTCAAGTTCAATGAAAGACTTTACAAAAGCAAACAAAG
Motif Score 3.319380952
Cell/Tissue List iSLK; TREX
Seq Type List MeRIP-seq
Transcript ID List ENST00000508498.5; ENST00000273857.9; ENST00000610355.4
External Link RMBase: m6A_site_636760
mod ID: M6ASITE065680 Click to Show/Hide the Full List
mod site chr4:47595569-47595570:- [3]
Sequence AATTTGCATGTTTGTTTTGGACTAATTTTTTTCAATTTATT
Motif Score 4.065041667
Cell/Tissue List iSLK
Seq Type List MeRIP-seq
Transcript ID List ENST00000610355.4; ENST00000508498.5; ENST00000273857.9
External Link RMBase: m6A_site_636761
mod ID: M6ASITE065681 Click to Show/Hide the Full List
mod site chr4:47595615-47595616:- [3]
Sequence TACAGAAGCACTTTTCATGGACAGAAATGCTCAATCGTGCA
Motif Score 3.643047619
Cell/Tissue List iSLK
Seq Type List MeRIP-seq
Transcript ID List ENST00000273857.9; ENST00000508498.5; ENST00000610355.4
External Link RMBase: m6A_site_636762
mod ID: M6ASITE065682 Click to Show/Hide the Full List
mod site chr4:47595701-47595702:- [3]
Sequence AATTATAAGGATGATCAGAGACTTTTGCCAGCTACACTAAA
Motif Score 3.319380952
Cell/Tissue List iSLK
Seq Type List MeRIP-seq
Transcript ID List ENST00000610355.4; ENST00000273857.9; ENST00000508498.5; ENST00000502252.5
External Link RMBase: m6A_site_636763
mod ID: M6ASITE065683 Click to Show/Hide the Full List
mod site chr4:47595724-47595725:- [3]
Sequence CATCCAGACCTTTCTCCTAAACTAATTATAAGGATGATCAG
Motif Score 2.627720238
Cell/Tissue List iSLK
Seq Type List MeRIP-seq
Transcript ID List ENST00000273857.9; ENST00000502252.5; ENST00000610355.4; ENST00000505909.5; ENST00000508498.5
External Link RMBase: m6A_site_636764
mod ID: M6ASITE065684 Click to Show/Hide the Full List
mod site chr4:47595737-47595738:- [3]
Sequence AAAGACAGATTTACATCCAGACCTTTCTCCTAAACTAATTA
Motif Score 2.876744048
Cell/Tissue List iSLK
Seq Type List MeRIP-seq
Transcript ID List ENST00000273857.9; ENST00000502252.5; ENST00000508498.5; ENST00000505909.5; ENST00000610355.4
External Link RMBase: m6A_site_636765
mod ID: M6ASITE065685 Click to Show/Hide the Full List
mod site chr4:47595753-47595754:- [3]
Sequence TTCGTCGAATGGATTAAAAGACAGATTTACATCCAGACCTT
Motif Score 2.897386905
Cell/Tissue List iSLK
Seq Type List MeRIP-seq
Transcript ID List ENST00000505909.5; ENST00000502252.5; ENST00000508498.5; ENST00000610355.4; ENST00000273857.9
External Link RMBase: m6A_site_636766
mod ID: M6ASITE065686 Click to Show/Hide the Full List
mod site chr4:47600300-47600301:- [3]
Sequence GTCCGCATTATTTCTCTGGAACATTGTCAGTCCTACTTTGA
Motif Score 2.951386905
Cell/Tissue List iSLK
Seq Type List MeRIP-seq
Transcript ID List ENST00000505909.5; ENST00000502252.5; ENST00000273857.9; ENST00000610355.4; ENST00000508498.5
External Link RMBase: m6A_site_636767
mod ID: M6ASITE065687 Click to Show/Hide the Full List
mod site chr4:47603495-47603496:- [3]
Sequence TGAGTGAAGACATCAGTGAGACTGGCTACGTCCGGCCTGTC
Motif Score 3.319380952
Cell/Tissue List iSLK
Seq Type List MeRIP-seq
Transcript ID List ENST00000508498.5; ENST00000273857.9; ENST00000610355.4; ENST00000502252.5; ENST00000505909.5
External Link RMBase: m6A_site_636768
mod ID: M6ASITE065688 Click to Show/Hide the Full List
mod site chr4:47603506-47603507:- [3]
Sequence CATCGTTGAGCTGAGTGAAGACATCAGTGAGACTGGCTACG
Motif Score 2.897386905
Cell/Tissue List iSLK
Seq Type List MeRIP-seq
Transcript ID List ENST00000273857.9; ENST00000502252.5; ENST00000610355.4; ENST00000508498.5; ENST00000505909.5
External Link RMBase: m6A_site_636769
mod ID: M6ASITE065689 Click to Show/Hide the Full List
mod site chr4:47665179-47665180:- [4]
Sequence CAAATTATTTTGGCCACAGGACTCAAAAGGAAGCATCCATC
Motif Score 4.065041667
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000503821.5; ENST00000502252.5; ENST00000610355.4; ENST00000504584.1; ENST00000273857.9; ENST00000505909.5; ENST00000508498.5
External Link RMBase: m6A_site_636770
mod ID: M6ASITE065690 Click to Show/Hide the Full List
mod site chr4:47665237-47665238:- [4]
Sequence TGTGAACCAATTACATTGGAACTCTGCATGAATTTGCCCTA
Motif Score 3.373380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000610355.4; ENST00000503821.5; ENST00000504584.1; ENST00000273857.9; ENST00000505909.5; ENST00000508498.5; ENST00000502252.5
External Link RMBase: m6A_site_636771
mod ID: M6ASITE065691 Click to Show/Hide the Full List
mod site chr4:47665252-47665253:- [4]
Sequence TCTTTGTTAGGTCAATGTGAACCAATTACATTGGAACTCTG
Motif Score 2.930744048
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000502252.5; ENST00000508498.5; ENST00000610355.4; ENST00000505909.5; ENST00000503821.5; ENST00000273857.9; ENST00000504584.1
External Link RMBase: m6A_site_636772
mod ID: M6ASITE065692 Click to Show/Hide the Full List
mod site chr4:47674412-47674413:- [4]
Sequence TAGCTCTCTCTGTGACCCGAACAACAGTCTGAATAACTGTA
Motif Score 2.951386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000273857.9; ENST00000504584.1; ENST00000505909.5; ENST00000508498.5; ENST00000610355.4; ENST00000502252.5; ENST00000503821.5
External Link RMBase: m6A_site_636773
mod ID: M6ASITE065693 Click to Show/Hide the Full List
mod site chr4:47683810-47683811:- [5]
Sequence CGAGAATCTGTTTCACTGTCACACAGGCAAGTGCCTTAATT
Motif Score 2.047297619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000503821.5; ENST00000508498.5; ENST00000502726.5; ENST00000273857.9; ENST00000504584.1; ENST00000502252.5; ENST00000505909.5; ENST00000610355.4
External Link RMBase: m6A_site_636774
mod ID: M6ASITE065694 Click to Show/Hide the Full List
mod site chr4:47744576-47744577:- [4]
Sequence TTTTTTTTTTTTAGTCATGGACTCCTGCCCTGTAGGTCCTT
Motif Score 4.065041667
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000502252.5; ENST00000505909.5; ENST00000273857.9; ENST00000610355.4; ENST00000504584.1; ENST00000502726.5; ENST00000508498.5; ENST00000503821.5
External Link RMBase: m6A_site_636776