General Information of the m6A Target Gene (ID: M6ATAR00996)
Target Name Myocardial zonula adherens protein (MYZAP)
Synonyms
GRINL1A upstream protein; Gup
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Gene Name Myzap
Chromosomal Location 15q21.3
Family MYZAP family
Function
Plays a role in cellular signaling via Rho-related GTP-binding proteins and subsequent activation of transcription factor SRF (By similarity). Targets TJP1 to cell junctions. In cortical neurons, may play a role in glutaminergic signal transduction through interaction with the NMDA receptor subunit GRIN1 (By similarity).
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Gene ID 1.01E+14
Uniprot ID
MYZAP_HUMAN
HGNC ID
HGNC:43444
KEGG ID
hsa:100820829hsa:145781
References
Ref 1 Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation. Mol Pharmacol. 2003 Jul;64(1):160-9. doi: 10.1124/mol.64.1.160.