m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00978)
Target Name Fatty acid-binding protein 5 (FABP5)
Synonyms
Epidermal-type fatty acid-binding protein; E-FABP; Fatty acid-binding protein, epidermal; Psoriasis-associated fatty acid-binding protein homolog; PA-FABP
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Gene Name FABP5
Chromosomal Location 8q21.13
Family Calycin superfamily, Fatty-acid binding protein (FABP) family
Function
Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors (PubMed:22170058, PubMed:21395585). Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation (By similarity). May be involved in keratinocyte differentiation (PubMed:8092987).
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Gene ID 2171
Uniprot ID
FABP5_HUMAN
HGNC ID
HGNC:3560
KEGG ID
hsa:2171
RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00978)
Fatty acid-binding protein 5 (FABP5)
N6-methyladenosine (m6A)
In total 12 m6A sequence/site(s) in this target gene
mod ID: M6ASITE085729 Click to Show/Hide the Full List
mod site chr8:81280554-81280555:+ [2]
Sequence CACAGCACGCTGCCACGCCGACGCAGACCCCTCTCTGCACG
Motif Score 2.839505952
Cell/Tissue List A549
Seq Type List m6A-CLIP/IP
Transcript ID List ENST00000297258.11
External Link RMBase: m6A_site_801814
mod ID: M6ASITE085730 Click to Show/Hide the Full List
mod site chr8:81280560-81280561:+ [3]
Sequence ACGCTGCCACGCCGACGCAGACCCCTCTCTGCACGCCAGCC
Motif Score 2.876744048
Cell/Tissue List HEK293T; HepG2; U2OS; H1A; H1B; hESCs; fibroblasts; A549; H1299; MM6; Jurkat; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List MeRIP-seq; m6A-seq
Transcript ID List ENST00000297258.11
External Link RMBase: m6A_site_801815
mod ID: M6ASITE085731 Click to Show/Hide the Full List
mod site chr8:81280638-81280639:+ [4]
Sequence AGGAAGATGGCGCCTGGTGGACAGCAAAGGCTTTGATGAAT
Motif Score 3.643047619
Cell/Tissue List HepG2; A549; HEK293T; U2OS; H1A; H1B; hESCs; fibroblasts; MM6; Huh7; Jurkat; CD4T; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000297258.11
External Link RMBase: m6A_site_801817
mod ID: M6ASITE085732 Click to Show/Hide the Full List
mod site chr8:81280659-81280660:+ [5]
Sequence CAGCAAAGGCTTTGATGAATACATGAAGGAGCTAGGTGAGG
Motif Score 2.110482143
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000297258.11
External Link RMBase: m6A_site_801818
mod ID: M6ASITE085733 Click to Show/Hide the Full List
mod site chr8:81283437-81283438:+ [6]
Sequence CATCACTTGTGATGGTAAAAACCTCACCATAAAAACTGAGA
Motif Score 2.185083333
Cell/Tissue List fibroblasts
Seq Type List m6A-seq
Transcript ID List ENST00000486269.1; ENST00000396359.1; ENST00000297258.11; ENST00000481695.1
External Link RMBase: m6A_site_801819
mod ID: M6ASITE085734 Click to Show/Hide the Full List
mod site chr8:81283469-81283470:+ [5]
Sequence AAACTGAGAGCACTTTGAAAACAACACAGTTTTCTTGTACC
Motif Score 2.20572619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000481695.1; ENST00000297258.11; ENST00000396359.1; ENST00000486269.1
External Link RMBase: m6A_site_801820
mod ID: M6ASITE085735 Click to Show/Hide the Full List
mod site chr8:81283472-81283473:+ [5]
Sequence CTGAGAGCACTTTGAAAACAACACAGTTTTCTTGTACCCTG
Motif Score 2.173910714
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000396359.1; ENST00000481695.1; ENST00000297258.11; ENST00000486269.1
External Link RMBase: m6A_site_801821
mod ID: M6ASITE085736 Click to Show/Hide the Full List
mod site chr8:81283935-81283936:+ [5]
Sequence AGTGGGATGGGAAGGAAAGCACAATAACAAGAAAATTGAAA
Motif Score 2.830589286
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000297258.11; ENST00000486269.1; ENST00000396359.1; ENST00000481695.1
External Link RMBase: m6A_site_801822
mod ID: M6ASITE085737 Click to Show/Hide the Full List
mod site chr8:81283941-81283942:+ [5]
Sequence ATGGGAAGGAAAGCACAATAACAAGAAAATTGAAAGATGGG
Motif Score 2.168095238
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000297258.11; ENST00000481695.1; ENST00000396359.1
External Link RMBase: m6A_site_801823
mod ID: M6ASITE085738 Click to Show/Hide the Full List
mod site chr8:81284526-81284527:+ [5]
Sequence CTTCTAGGAGTGTGTCATGAACAATGTCACCTGTACTCGGA
Motif Score 2.951386905
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000396359.1; ENST00000297258.11
External Link RMBase: m6A_site_801824
mod ID: M6ASITE085739 Click to Show/Hide the Full List
mod site chr8:81284692-81284693:+ [5]
Sequence TTCAATTATCTTTATCATAAACATTTTACATGCAGCTATTT
Motif Score 2.20572619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000297258.11; ENST00000396359.1
External Link RMBase: m6A_site_801825
mod ID: M6ASITE085740 Click to Show/Hide the Full List
mod site chr8:81284699-81284700:+ [5]
Sequence ATCTTTATCATAAACATTTTACATGCAGCTATTTCAAAGTG
Motif Score 2.07285119
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000297258.11; ENST00000396359.1
External Link RMBase: m6A_site_801826