m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00953)

Target Name	Interferon epsilon (IFNE)
Synonyms	IFN-epsilon; Interferon epsilon-1 Click to Show/Hide
Gene Name	IFNE
Chromosomal Location	9p21.3
Family	Alpha/beta interferon family
Function	Type I interferon required for maintaining basal levels of IFN-regulated genes, including 2'-5'-oligoadenylate synthetase, IRF7 and ISG15, in the female reproductive tract. Directly mediates protection against viral and bacterial genital infections (By similarity). Click to Show/Hide
Gene ID	338376
Uniprot ID	IFNE_HUMAN
HGNC ID	HGNC:18163
KEGG ID	hsa:338376

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00953)

Interferon epsilon (IFNE)

N6-methyladenosine (m6A)

In total 22 m6A sequence/site(s) in this target gene
mod ID: M6ASITE087738		Click to Show/Hide the Full List
mod site	chr9:21481040-21481041:-		[2]
Sequence	GGACTAGAGGACTTCTCCAGACATGATTCTTCATAGAGTGG
Motif Score	2.897386905
Cell/Tissue List	A549; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000304425.3; ENST00000448696.4
External Link	RMBase: m6A_site_817594
mod ID: M6ASITE087739		Click to Show/Hide the Full List
mod site	chr9:21481050-21481051:-		[3]
Sequence	GTAGGTGGAGGGACTAGAGGACTTCTCCAGACATGATTCTT
Motif Score	4.065041667
Cell/Tissue List	HeLa; A549; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000304425.3; ENST00000448696.4
External Link	RMBase: m6A_site_817595
mod ID: M6ASITE087740		Click to Show/Hide the Full List
mod site	chr9:21481058-21481059:-		[3]
Sequence	AGCCCGAGGTAGGTGGAGGGACTAGAGGACTTCTCCAGACA
Motif Score	4.065041667
Cell/Tissue List	HeLa; A549; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000448696.4; ENST00000304425.3
External Link	RMBase: m6A_site_817596
mod ID: M6ASITE087741		Click to Show/Hide the Full List
mod site	chr9:21481121-21481122:-		[3]
Sequence	AAACTGAGCAAACAAGGAAGACCCTTGAACGACATGAAGCA
Motif Score	2.876744048
Cell/Tissue List	HeLa; fibroblasts; A549; iSLK; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000448696.4; ENST00000304425.3
External Link	RMBase: m6A_site_817597
mod ID: M6ASITE087742		Click to Show/Hide the Full List
mod site	chr9:21481130-21481131:-		[3]
Sequence	CTCACAGAAAAACTGAGCAAACAAGGAAGACCCTTGAACGA
Motif Score	2.20572619
Cell/Tissue List	HeLa; fibroblasts; A549; iSLK; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000304425.3; ENST00000448696.4
External Link	RMBase: m6A_site_817598
mod ID: M6ASITE087743		Click to Show/Hide the Full List
mod site	chr9:21481139-21481140:-		[3]
Sequence	GTGTTCAGTCTCACAGAAAAACTGAGCAAACAAGGAAGACC
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T; fibroblasts; A549; iSLK; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000448696.4; ENST00000304425.3
External Link	RMBase: m6A_site_817599
mod ID: M6ASITE087744		Click to Show/Hide the Full List
mod site	chr9:21481218-21481219:-		[3]
Sequence	TGATTACCTGGAAAACCAGGACTACAGCACCTGTGCCTGGG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T; HepG2; fibroblasts; A549; MSC; TIME; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000448696.4; ENST00000304425.3
External Link	RMBase: m6A_site_817600
mod ID: M6ASITE087745		Click to Show/Hide the Full List
mod site	chr9:21481224-21481225:-		[4]
Sequence	GATCCATGATTACCTGGAAAACCAGGACTACAGCACCTGTG
Motif Score	2.185083333
Cell/Tissue List	HEK293T; HepG2; fibroblasts; A549; iSLK; MSC; TIME
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000304425.3; ENST00000448696.4
External Link	RMBase: m6A_site_817601
mod ID: M6ASITE087746		Click to Show/Hide the Full List
mod site	chr9:21481319-21481320:-		[4]
Sequence	TACCTAGAAGCACTCATGGGACTGGAAGCAGAGAAGCTAAG
Motif Score	4.065041667
Cell/Tissue List	HepG2; fibroblasts; A549; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000304425.3; ENST00000448696.4
External Link	RMBase: m6A_site_817602
mod ID: M6ASITE087747		Click to Show/Hide the Full List
mod site	chr9:21481383-21481384:-		[4]
Sequence	TCTGGATGGTTGGGAGGAAAACCACACGGAGAAATTCCTCA
Motif Score	2.185083333
Cell/Tissue List	HepG2; A549; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000448696.4; ENST00000304425.3
External Link	RMBase: m6A_site_817603
mod ID: M6ASITE087748		Click to Show/Hide the Full List
mod site	chr9:21481469-21481470:-		[2]
Sequence	CCTCAGCAGTACCAAAAAGGACACACTCTGGCCATTCTCCA
Motif Score	3.643047619
Cell/Tissue List	HEK293T; A549; MSC; TIME
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000304425.3; ENST00000448696.4
External Link	RMBase: m6A_site_817604
mod ID: M6ASITE087749		Click to Show/Hide the Full List
mod site	chr9:21481518-21481519:-		[2]
Sequence	GTGTCTACCACACAGGAAAAACTTTCTGCTTCCTCAGAAGT
Motif Score	2.627720238
Cell/Tissue List	HEK293T; A549; MSC; TIME
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000304425.3; ENST00000448696.4
External Link	RMBase: m6A_site_817605
mod ID: M6ASITE087750		Click to Show/Hide the Full List
mod site	chr9:21481555-21481556:-		[2]
Sequence	AACTCTTGAATAAGTTGCAAACCTTGTCAATTCAGCAGTGT
Motif Score	2.185083333
Cell/Tissue List	HEK293T; A549; MSC; TIME
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000448696.4; ENST00000304425.3
External Link	RMBase: m6A_site_817606
mod ID: M6ASITE087751		Click to Show/Hide the Full List
mod site	chr9:21481574-21481575:-		[2]
Sequence	GTGAATCAAGAAAGTTTAAAACTCTTGAATAAGTTGCAAAC
Motif Score	2.627720238
Cell/Tissue List	HEK293T; A549; MSC; TIME
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000304425.3; ENST00000448696.4
External Link	RMBase: m6A_site_817607
mod ID: M6ASITE087752		Click to Show/Hide the Full List
mod site	chr9:21481598-21481599:-		[2]
Sequence	CTGATTATCTTCCAGCAAAGACAAGTGAATCAAGAAAGTTT
Motif Score	2.897386905
Cell/Tissue List	HEK293T; A549; MSC; TIME
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000448696.4; ENST00000304425.3
External Link	RMBase: m6A_site_817608
mod ID: M6ASITE087753		Click to Show/Hide the Full List
mod site	chr9:21481619-21481620:-		[2]
Sequence	ATCTTCTCTCTAGATTTGAAACTGATTATCTTCCAGCAAAG
Motif Score	2.627720238
Cell/Tissue List	HEK293T; A549; MSC; TIME
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000448696.4; ENST00000304425.3
External Link	RMBase: m6A_site_817609
mod ID: M6ASITE087754		Click to Show/Hide the Full List
mod site	chr9:21481669-21481670:-		[3]
Sequence	TTATCAAGCACTTCTTTGGAACTGTGTTGGTGCTGCTGGCC
Motif Score	3.373380952
Cell/Tissue List	HeLa; A549; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000304425.3; ENST00000448696.4
External Link	RMBase: m6A_site_817610
mod ID: M6ASITE087755		Click to Show/Hide the Full List
mod site	chr9:21481758-21481759:-		[2]
Sequence	CTGAGATGCATGAAAGGCAAACATTCACTAGAGCTGGAATT
Motif Score	2.20572619
Cell/Tissue List	A549; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000304425.3; ENST00000448696.4
External Link	RMBase: m6A_site_817611
mod ID: M6ASITE087756		Click to Show/Hide the Full List
mod site	chr9:21481795-21481796:-		[5]
Sequence	AACGAAAGCAACAAAAGAGAACACTCTCCAAAATAATCTGA
Motif Score	2.951386905
Cell/Tissue List	MSC
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000448696.4; ENST00000304425.3
External Link	RMBase: m6A_site_817612
mod ID: M6ASITE087757		Click to Show/Hide the Full List
mod site	chr9:21481837-21481838:-		[5]
Sequence	CCTGAAAATCTAATGTGTAAACTTGGAGAAATGACATTAGA
Motif Score	2.627720238
Cell/Tissue List	MSC
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000448696.4; ENST00000304425.3
External Link	RMBase: m6A_site_817613
mod ID: M6ASITE087758		Click to Show/Hide the Full List
mod site	chr9:21481858-21481859:-		[5]
Sequence	CTGAACACCATGAAAAGGGAACCTGAAAATCTAATGTGTAA
Motif Score	2.930744048
Cell/Tissue List	MSC
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000304425.3; ENST00000448696.4
External Link	RMBase: m6A_site_817614
mod ID: M6ASITE087759		Click to Show/Hide the Full List
mod site	chr9:21481874-21481875:-		[5]
Sequence	ATGGAGAAAATGTACTCTGAACACCATGAAAAGGGAACCTG
Motif Score	2.951386905
Cell/Tissue List	MSC
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000448696.4; ENST00000304425.3
External Link	RMBase: m6A_site_817615

Ref 1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1443).
Ref 2	Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. Cell Rep. 2014 Jul 10;8(1):284-96. doi: 10.1016/j.celrep.2014.05.048. Epub 2014 Jun 26.
Ref 3	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 4	Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq. Nature. 2012 Apr 29;485(7397):201-6. doi: 10.1038/nature11112.
Ref 5	Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018 Jan;3(1):108-120. doi: 10.1038/s41564-017-0056-8. Epub 2017 Nov 6.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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