m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00934)

Target Name	glucosylceramidase beta 1 like, pseudogene (GBA1LP)
Synonyms	GBAP; glucosidase, beta; acid, pseudogene Click to Show/Hide
Gene Name	GBAP1
Chromosomal Location	1q22
Gene ID	2630
HGNC ID	HGNC:4178

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00934)

glucosylceramidase beta 1 like, pseudogene (GBA1LP)

Adenosine-to-Inosine editing (A-to-I)

In total 4 m6A sequence/site(s) in this target gene
mod ID: A2ISITE011468		Click to Show/Hide the Full List
mod site	chr1:155220522-155220523:-		[2]
Sequence	ATTGCTTGAACCTGGGAGGCAGAGGTTGCGGTGAGCTGAGA
Transcript ID List	ENST00000368374.5; rmsk_272494
External Link	RMBase: RNA-editing_site_9437
mod ID: A2ISITE011469		Click to Show/Hide the Full List
mod site	chr1:155221233-155221234:-		[2]
Sequence	GCGTGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAAGC
Transcript ID List	ENST00000368374.5; rmsk_272495
External Link	RMBase: RNA-editing_site_9438
mod ID: A2ISITE011470		Click to Show/Hide the Full List
mod site	chr1:155221589-155221590:-		[2]
Sequence	TCCCAAGTAGCTGGGATTACAGGCGTGCACCACCACACCCA
Transcript ID List	ENST00000368374.5
External Link	RMBase: RNA-editing_site_9439
mod ID: A2ISITE011471		Click to Show/Hide the Full List
mod site	chr1:155224052-155224053:-		[3]
Sequence	TAAGGTGGGAGGATCCCTTGAGCCCAGGTGGTCGAGGCTGC
Transcript ID List	ENST00000368374.5; rmsk_272507
External Link	RMBase: RNA-editing_site_9440

5-methylcytidine (m5C)

In total 2 m6A sequence/site(s) in this target gene
mod ID: M5CSITE003794		Click to Show/Hide the Full List
mod site	chr1:155215156-155215157:-		[4]
Sequence	TTGTCCTTACCCTAGAACCTCCTGTACCATGTGGTCGGCTG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000459805.5; ENST00000486869.5; ENST00000473223.5; ENST00000368374.5; ENST00000486197.5; ENST00000566701.5
External Link	RMBase: m5C_site_3710
mod ID: M5CSITE003795		Click to Show/Hide the Full List
mod site	chr1:155216995-155216996:-		[4]
Sequence	ACCGAGCCCTGCAGTTGGCCCAGCGTCCCGTTTCACTCCTT
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000566701.5; ENST00000463838.5; ENST00000368374.5; ENST00000462587.1; ENST00000459805.5; ENST00000473223.5; ENST00000486197.5; ENST00000486869.5
External Link	RMBase: m5C_site_3713

N6-methyladenosine (m6A)

In total 4 m6A sequence/site(s) in this target gene
mod ID: M6ASITE058143		Click to Show/Hide the Full List
mod site	chr1:155214417-155214418:-		[5]
Sequence	CTGCTGTGGGCTTCCTGGAGACAATCTCACCTGGCTACTCC
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000473223.5; ENST00000459805.5; ENST00000368374.5; ENST00000566701.5; ENST00000486869.5; ENST00000486197.5
External Link	RMBase: m6A_site_56577
mod ID: M6ASITE058144		Click to Show/Hide the Full List
mod site	chr1:155214570-155214571:-		[5]
Sequence	TGCTGTTGTGGTCGTGCTAAACCGGTGAGGGCAATGGTGAG
Motif Score	2.185083333
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000486869.5; ENST00000368374.5; ENST00000566701.5; ENST00000473223.5; ENST00000459805.5; ENST00000486197.5
External Link	RMBase: m6A_site_56578
mod ID: M6ASITE058145		Click to Show/Hide the Full List
mod site	chr1:155215085-155215086:-		[5]
Sequence	ACCAAGCACACGTTTTACAAACAGCCCATGTTCTACCACCT
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000459805.5; ENST00000486869.5; ENST00000368374.5; ENST00000566701.5; ENST00000486197.5; ENST00000473223.5
External Link	RMBase: m6A_site_56579
mod ID: M6ASITE058146		Click to Show/Hide the Full List
mod site	chr1:155216574-155216575:-		[6]
Sequence	AGTTACAGTTCTGGGCAGTGACAGCTGAAAATGAGCCTTCT
Motif Score	2.859755952
Cell/Tissue List	brain
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000486197.5; ENST00000459805.5; ENST00000368374.5; ENST00000566701.5; ENST00000463838.5; ENST00000486869.5; ENST00000473223.5
External Link	RMBase: m6A_site_56580

Pseudouridine (Pseudo)

In total 1 m6A sequence/site(s) in this target gene
mod ID: PSESITE000240		Click to Show/Hide the Full List
mod site	chr1:155214058-155214059:-		[7]
Sequence	TAGGGTGAGCTCACTGTCCGTACAAACACAAGATCAGGGCT
Transcript ID List	ENST00000368374.5; ENST00000486197.5; ENST00000486869.5; ENST00000473223.5; ENST00000459805.5
External Link	RMBase: Pseudo_site_431

Ref 1	Peroxisome proliferator-activated receptor alpha/gamma dual agonists for the treatment of type 2 diabetes. J Med Chem. 2004 Aug 12;47(17):4118-27. doi: 10.1021/jm030631e.
Ref 2	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 3	Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome. Nat Biotechnol. 2012 Feb 12;30(3):253-60. doi: 10.1038/nbt.2122.
Ref 4	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 5	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 6	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 7	Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome. Nat Chem Biol. 2015 Aug;11(8):592-7. doi: 10.1038/nchembio.1836. Epub 2015 Jun 15.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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