m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00928)

Target Name	Adipogenesis regulatory factor (ADIRF)
Synonyms	Adipogenesis factor rich in obesity; Adipose most abundant gene transcript 2 protein; Adipose-specific protein 2; apM-2 Click to Show/Hide
Gene Name	ADIRF
Chromosomal Location	10q23.2
Function	Plays a role in fat cell development; promotes adipogenic differentiation and stimulates transcription initiation of master adipogenesis factors like PPARG and CEBPA at early stages of preadipocyte differentiation. Its overexpression confers resistance to the anticancer chemotherapeutic drug cisplatin. Click to Show/Hide
Gene ID	10974
Uniprot ID	ADIRF_HUMAN
HGNC ID	HGNC:24043
KEGG ID	hsa:10974

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00928)

Adipogenesis regulatory factor (ADIRF)

Adenosine-to-Inosine editing (A-to-I)

In total 1 m6A sequence/site(s) in this target gene
mod ID: A2ISITE004309		Click to Show/Hide the Full List
mod site	chr10:86977175-86977176:+		[2]
Sequence	CTGCCTCCTGGGTTCACGCAATTCTCCTGCCTCAGCCTCCC
Transcript ID List	ENST00000561504.1; ENST00000433214.2
External Link	RMBase: RNA-editing_site_17272

N6-methyladenosine (m6A)

In total 22 m6A sequence/site(s) in this target gene
mod ID: M6ASITE001143		Click to Show/Hide the Full List
mod site	chr10:86968261-86968262:+		[3]
Sequence	TGCCTCCAGCTCCTCTCTGGACCCCTGTCCTGGCACCTCTT
Motif Score	3.622404762
Cell/Tissue List	HeLa; MM6; endometrial; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000372013.7
External Link	RMBase: m6A_site_108890
mod ID: M6ASITE001144		Click to Show/Hide the Full List
mod site	chr10:86968354-86968355:+		[3]
Sequence	ATGTGCTCCCTGCCCTGCGGACTCTGGAGCAGGGCCCGGCC
Motif Score	4.065041667
Cell/Tissue List	HeLa; MM6; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000372013.7
External Link	RMBase: m6A_site_108895
mod ID: M6ASITE001145		Click to Show/Hide the Full List
mod site	chr10:86968400-86968401:+		[3]
Sequence	CCGGAGCCTGTATGACGGGAACCGCCCCGCGCCCTCTCCCC
Motif Score	2.930744048
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000372013.7
External Link	RMBase: m6A_site_108896
mod ID: M6ASITE001146		Click to Show/Hide the Full List
mod site	chr10:86968456-86968457:+		[3]
Sequence	AGCCCTGGGGCGCCTTAAAAACCGGAGCTGGCGCTTGGCAT
Motif Score	2.185083333
Cell/Tissue List	HeLa; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000416348.1; ENST00000372013.7
External Link	RMBase: m6A_site_108897
mod ID: M6ASITE001147		Click to Show/Hide the Full List
mod site	chr10:86968566-86968567:+		[3]
Sequence	GGCAAGCAAGGGCTTGCAGGACCTGAAGCAACAGGTGGAGG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; MM6; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000561504.1; ENST00000416348.1; ENST00000372013.7
External Link	RMBase: m6A_site_108898
mod ID: M6ASITE001148		Click to Show/Hide the Full List
mod site	chr10:86968589-86968590:+		[3]
Sequence	TGAAGCAACAGGTGGAGGGGACCGCCCAGGAAGCCGGTGAG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; MM6; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000372013.7; ENST00000561504.1; ENST00000416348.1
External Link	RMBase: m6A_site_108899
mod ID: M6ASITE001149		Click to Show/Hide the Full List
mod site	chr10:86970235-86970236:+		[3]
Sequence	GGCAGCTCAGCAAGTGGTGGACCAGGCCACAGAGGCGGGGC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; U2OS; MM6; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000561504.1; ENST00000416348.1; ENST00000372013.7
External Link	RMBase: m6A_site_108925
mod ID: M6ASITE001150		Click to Show/Hide the Full List
mod site	chr10:86970481-86970482:+		[3]
Sequence	CCGCCCTTCCCCAGCCATGGACCAGCTGGCCAAGACCACCC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; U2OS; MM6; MSC; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000416348.1; ENST00000372013.7; ENST00000561504.1
External Link	RMBase: m6A_site_108930
mod ID: M6ASITE001151		Click to Show/Hide the Full List
mod site	chr10:86970495-86970496:+		[3]
Sequence	CCATGGACCAGCTGGCCAAGACCACCCAGGAAACCATCGAC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; U2OS; MM6; MSC; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000561504.1; ENST00000372013.7; ENST00000416348.1
External Link	RMBase: m6A_site_108931
mod ID: M6ASITE001152		Click to Show/Hide the Full List
mod site	chr10:86970507-86970508:+		[3]
Sequence	TGGCCAAGACCACCCAGGAAACCATCGACAAGACTGCTAAC
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; U2OS; MM6; peripheral-blood; MSC; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000561504.1; ENST00000372013.7; ENST00000416348.1
External Link	RMBase: m6A_site_108932
mod ID: M6ASITE001153		Click to Show/Hide the Full List
mod site	chr10:86970519-86970520:+		[3]
Sequence	CCCAGGAAACCATCGACAAGACTGCTAACCAGGCCTCTGAC
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; U2OS; MM6; peripheral-blood; MSC; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000372013.7; ENST00000416348.1; ENST00000561504.1
External Link	RMBase: m6A_site_108933
mod ID: M6ASITE001154		Click to Show/Hide the Full List
mod site	chr10:86970538-86970539:+		[4]
Sequence	GACTGCTAACCAGGCCTCTGACACCTTCTCTGGGATTGGGA
Motif Score	2.859755952
Cell/Tissue List	brain; kidney; liver
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000561504.1; ENST00000372013.7
External Link	RMBase: m6A_site_108934
mod ID: M6ASITE001155		Click to Show/Hide the Full List
mod site	chr10:86970592-86970593:+		[3]
Sequence	CCTGAAATGACAGCAGGGAGACTTGGGTCGGCCTCCTGAAA
Motif Score	3.319380952
Cell/Tissue List	HeLa; A549; U2OS; H1B; MM6; peripheral-blood; HEK293A-TOA; MSC; iSLK; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000372013.7; ENST00000561504.1
External Link	RMBase: m6A_site_108935
mod ID: M6ASITE001156		Click to Show/Hide the Full List
mod site	chr10:86970626-86970627:+		[3]
Sequence	CCTGAAATGACAGCAGGGAGACTTGGGTGACCCCCCTTCCA
Motif Score	3.319380952
Cell/Tissue List	HeLa; A549; U2OS; H1B; GM12878; MM6; Jurkat; peripheral-blood; HEK293A-TOA; MSC; TIME; TREX; iSLK; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000561504.1; ENST00000372013.7
External Link	RMBase: m6A_site_108936
mod ID: M6ASITE001157		Click to Show/Hide the Full List
mod site	chr10:86970891-86970892:+		[3]
Sequence	GCGCCTCCCGAAGCTCCCAGACCGGAGGCTCAGCCCCCATC
Motif Score	2.876744048
Cell/Tissue List	HeLa; A549; HepG2; U2OS; H1A; H1B; GM12878; MM6; Jurkat; HEK293A-TOA; MSC; TIME; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000561504.1; ENST00000433214.2; ENST00000372013.7
External Link	RMBase: m6A_site_108943
mod ID: M6ASITE001158		Click to Show/Hide the Full List
mod site	chr10:86983158-86983159:+		[3]
Sequence	GTAAAGCACTGCCTCCCTAGACCAATTCTCTGGGATCCCTG
Motif Score	2.876744048
Cell/Tissue List	HeLa; A549; MM6; HEK293A-TOA; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000433214.2; ENST00000561504.1
External Link	RMBase: m6A_site_108945
mod ID: M6ASITE001159		Click to Show/Hide the Full List
mod site	chr10:86983183-86983184:+		[3]
Sequence	TTCTCTGGGATCCCTGGAAGACATCTGGCATCCAGCAAGTC
Motif Score	2.897386905
Cell/Tissue List	HeLa; A549; MM6; HEK293A-TOA; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000561504.1; ENST00000433214.2
External Link	RMBase: m6A_site_108946
mod ID: M6ASITE001160		Click to Show/Hide the Full List
mod site	chr10:86983233-86983234:+		[3]
Sequence	CTTTAGAAAGCCATGGAGAAACTGGAGGCAATTCTGTTAAG
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000433214.2; ENST00000561504.1
External Link	RMBase: m6A_site_108947
mod ID: M6ASITE001161		Click to Show/Hide the Full List
mod site	chr10:86983877-86983878:+		[3]
Sequence	AATACCTGTTTTCTGACAAGACTAGGACTCTTACATAGACT
Motif Score	3.319380952
Cell/Tissue List	HeLa; A549; MM6; HEK293A-TOA; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000561504.1; ENST00000433214.2
External Link	RMBase: m6A_site_108948
mod ID: M6ASITE001162		Click to Show/Hide the Full List
mod site	chr10:86983883-86983884:+		[3]
Sequence	TGTTTTCTGACAAGACTAGGACTCTTACATAGACTGCCATG
Motif Score	4.065041667
Cell/Tissue List	HeLa; A549; MM6; HEK293A-TOA; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000433214.2; ENST00000561504.1
External Link	RMBase: m6A_site_108949
mod ID: M6ASITE001163		Click to Show/Hide the Full List
mod site	chr10:86983895-86983896:+		[3]
Sequence	AGACTAGGACTCTTACATAGACTGCCATGAACTACAAGAAG
Motif Score	3.319380952
Cell/Tissue List	HeLa; A549; MM6; HEK293A-TOA; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000433214.2; ENST00000561504.1
External Link	RMBase: m6A_site_108950
mod ID: M6ASITE001164		Click to Show/Hide the Full List
mod site	chr10:86983905-86983906:+		[3]
Sequence	TCTTACATAGACTGCCATGAACTACAAGAAGTATAGCATTG
Motif Score	3.373380952
Cell/Tissue List	HeLa; MM6; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000561504.1; ENST00000433214.2
External Link	RMBase: m6A_site_108951

Ref 1	Structure-activity studies of phenanthroindolizidine alkaloids as potential antitumor agents. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4338-42. doi: 10.1016/j.bmcl.2007.05.021. Epub 2007 May 16.
Ref 2	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 3	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 4	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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