m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00927)
Target Name GTP cyclohydrolase 1 (GCH1)
Synonyms
EC 3.5.4.16; GTP cyclohydrolase I; GTP-CH-I
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Gene Name gch1
Chromosomal Location 14q22.2
Family GTP cyclohydrolase I family
Function
Positively regulates nitric oxide synthesis in umbilical vein endothelial cells (HUVECs). May be involved in dopamine synthesis. May modify pain sensitivity and persistence. Isoform GCH-1 is the functional enzyme, the potential function of the enzymatically inactive isoforms remains unknown.
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Gene ID 2643
Uniprot ID
GCH1_HUMAN
HGNC ID
HGNC:4193
KEGG ID
hsa:2643
References
Ref 1 Effects of hEGF (MG111) on gastric mucosal potential difference in rats. Scand J Gastroenterol Suppl. 1989;162:198-201. doi: 10.3109/00365528909091160.