m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00920)
Target Name Keratin, type I cytoskeletal 17 (KRT17)
Synonyms
39.1; Cytokeratin-17; Keratin-17; CK-17; K17
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Gene Name KRT17
Chromosomal Location 17q21.2
Family Intermediate filament family
Function
Type I keratin involved in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair (By similarity). Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial 'stem cells'. Acts as a promoter of epithelial proliferation by acting a regulator of immune response in skin: promotes Th1/Th17-dominated immune environment contributing to the development of basaloid skin tumors (By similarity). May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation.
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Gene ID 3872
Uniprot ID
K1C17_HUMAN
HGNC ID
HGNC:6427
KEGG ID
hsa:3872
RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00920)
Keratin, type I cytoskeletal 17 (KRT17)
5-methylcytidine (m5C)
In total 2 m6A sequence/site(s) in this target gene
mod ID: M5CSITE001116 Click to Show/Hide the Full List
mod site chr17:41619623-41619624:- [2]
Sequence GATGGCAAGGTCATCTCCTCCCGCGAGCAGGTCCACCAGAC
Seq Type List Bisulfite-seq
Transcript ID List ENST00000649249.1; ENST00000540235.5; ENST00000493253.5; ENST00000648886.1; ENST00000311208.13
External Link RMBase: m5C_site_18844
mod ID: M5CSITE001117 Click to Show/Hide the Full List
mod site chr17:41624476-41624477:- [2]
Sequence ATCCGCCAGTTCACCTCCTCCAGCTCCATCAAGGGCTCCTC
Seq Type List Bisulfite-seq
Transcript ID List ENST00000463128.5; ENST00000648886.1; ENST00000540235.5; ENST00000491673.1; ENST00000311208.13
External Link RMBase: m5C_site_18845
N6-methyladenosine (m6A)
In total 28 m6A sequence/site(s) in this target gene
mod ID: M6ASITE032428 Click to Show/Hide the Full List
mod site chr17:41619590-41619591:- [3]
Sequence CACCAGACCACCCGCTGAGGACTCAGCTACCCCGGCCGGCC
Motif Score 4.065041667
Cell/Tissue List HeLa; HepG2; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000311208.13; ENST00000540235.5; ENST00000648886.1; ENST00000493253.5; ENST00000649249.1
External Link RMBase: m6A_site_362386
mod ID: M6ASITE032429 Click to Show/Hide the Full List
mod site chr17:41619604-41619605:- [3]
Sequence CCCGCGAGCAGGTCCACCAGACCACCCGCTGAGGACTCAGC
Motif Score 2.876744048
Cell/Tissue List HeLa; HepG2; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000311208.13; ENST00000493253.5; ENST00000540235.5; ENST00000649249.1; ENST00000648886.1
External Link RMBase: m6A_site_362387
mod ID: M6ASITE032430 Click to Show/Hide the Full List
mod site chr17:41620195-41620196:- [3]
Sequence CAGCTTTTGGATGAGCAAAAACAGTCCTGTCTCTGGGGTCT
Motif Score 2.20572619
Cell/Tissue List HeLa; HepG2; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000648859.1; ENST00000493253.5; ENST00000540235.5; ENST00000311208.13; ENST00000649249.1; ENST00000648886.1
External Link RMBase: m6A_site_362388
mod ID: M6ASITE032431 Click to Show/Hide the Full List
mod site chr17:41620242-41620243:- [3]
Sequence CATCTGATGGGAAGATAGGAACATGGTCTCATGATCTTTGC
Motif Score 2.951386905
Cell/Tissue List HeLa; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000540235.5; ENST00000648859.1; ENST00000648886.1; ENST00000493253.5; ENST00000649249.1; ENST00000311208.13
External Link RMBase: m6A_site_362389
mod ID: M6ASITE032432 Click to Show/Hide the Full List
mod site chr17:41620286-41620287:- [3]
Sequence ATCCTAGTCTGATGGAGGAGACAGGTCCCAGCTCTGGAGAT
Motif Score 2.897386905
Cell/Tissue List HeLa; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000649249.1; ENST00000311208.13; ENST00000648859.1; ENST00000493253.5; ENST00000648886.1; ENST00000540235.5
External Link RMBase: m6A_site_362390
mod ID: M6ASITE032433 Click to Show/Hide the Full List
mod site chr17:41620325-41620326:- [3]
Sequence TGATGGGGGTGGGGCAGGGAACTGGTCCTTACCTTGGAGAT
Motif Score 3.373380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000648859.1; ENST00000540235.5; ENST00000648886.1; ENST00000493253.5; ENST00000649249.1; ENST00000311208.13
External Link RMBase: m6A_site_362391
mod ID: M6ASITE032434 Click to Show/Hide the Full List
mod site chr17:41620490-41620491:- [4]
Sequence CTGGGGGTTGGGTGCATGGGACAGGCAGCCCACCTGCACGT
Motif Score 3.643047619
Cell/Tissue List endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000311208.13; ENST00000648859.1; ENST00000649249.1; ENST00000540235.5; ENST00000493253.5; ENST00000648886.1
External Link RMBase: m6A_site_362392
mod ID: M6ASITE032435 Click to Show/Hide the Full List
mod site chr17:41620748-41620749:- [3]
Sequence CTGCGAGATGGAGCAGCAGAACCAGGAATACAAAATCCTGC
Motif Score 2.930744048
Cell/Tissue List HeLa; HepG2; U2OS; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000648859.1; ENST00000493253.5; ENST00000649249.1; ENST00000540235.5; ENST00000311208.13; ENST00000648886.1
External Link RMBase: m6A_site_362393
mod ID: M6ASITE032436 Click to Show/Hide the Full List
mod site chr17:41620841-41620842:- [3]
Sequence CAACCTGGCGGAGACAGAGAACCGCTACTGCGTGCAGCTGT
Motif Score 2.930744048
Cell/Tissue List HeLa; HepG2; U2OS; GSC-11; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000648886.1; ENST00000311208.13; ENST00000649249.1; ENST00000493253.5; ENST00000540235.5
External Link RMBase: m6A_site_362394
mod ID: M6ASITE032437 Click to Show/Hide the Full List
mod site chr17:41620848-41620849:- [3]
Sequence TGGAGGGCAACCTGGCGGAGACAGAGAACCGCTACTGCGTG
Motif Score 2.897386905
Cell/Tissue List HeLa; HepG2; U2OS; GSC-11; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000311208.13; ENST00000493253.5; ENST00000540235.5; ENST00000649249.1; ENST00000648886.1
External Link RMBase: m6A_site_362395
mod ID: M6ASITE032438 Click to Show/Hide the Full List
mod site chr17:41621077-41621078:- [3]
Sequence TCTGCAGACAGAGGAACTGAACCGCGAGGTGGCCACCAACA
Motif Score 2.930744048
Cell/Tissue List HeLa; HepG2; U2OS; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000649249.1; ENST00000540235.5; ENST00000648886.1; ENST00000493253.5; ENST00000311208.13; ENST00000463128.5
External Link RMBase: m6A_site_362396
mod ID: M6ASITE032439 Click to Show/Hide the Full List
mod site chr17:41621082-41621083:- [3]
Sequence TCCTGTCTGCAGACAGAGGAACTGAACCGCGAGGTGGCCAC
Motif Score 3.373380952
Cell/Tissue List HeLa; HepG2; U2OS; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000463128.5; ENST00000311208.13; ENST00000648886.1; ENST00000649249.1; ENST00000493253.5; ENST00000540235.5
External Link RMBase: m6A_site_362397
mod ID: M6ASITE032440 Click to Show/Hide the Full List
mod site chr17:41621090-41621091:- [3]
Sequence GTCCTGTGTCCTGTCTGCAGACAGAGGAACTGAACCGCGAG
Motif Score 2.897386905
Cell/Tissue List HeLa; HepG2; U2OS; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000540235.5; ENST00000648886.1; ENST00000463128.5; ENST00000649249.1; ENST00000311208.13; ENST00000493253.5
External Link RMBase: m6A_site_362398
mod ID: M6ASITE032441 Click to Show/Hide the Full List
mod site chr17:41621626-41621627:- [3]
Sequence TGAGAAGATGGCAGAGAAGAACCGCAAGGATGCCGAGGATT
Motif Score 2.930744048
Cell/Tissue List HeLa; HepG2; U2OS; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000577817.3; ENST00000540235.5; ENST00000648886.1; ENST00000493253.5; ENST00000311208.13; ENST00000463128.5
External Link RMBase: m6A_site_362399
mod ID: M6ASITE032442 Click to Show/Hide the Full List
mod site chr17:41621683-41621684:- [3]
Sequence GGACGCTGCCCCAGGCGTGGACCTGAGCCGCATCCTCAACG
Motif Score 3.622404762
Cell/Tissue List HeLa; HepG2; U2OS; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000648886.1; ENST00000311208.13; ENST00000463128.5; ENST00000590038.1; ENST00000577817.3; ENST00000540235.5; ENST00000493253.5
External Link RMBase: m6A_site_362400
mod ID: M6ASITE032443 Click to Show/Hide the Full List
mod site chr17:41621862-41621863:- [3]
Sequence TCAGATAGAGCAGAGGGAGAACAAAGGAGGGGTCCTTGTGG
Motif Score 2.951386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000577817.3; ENST00000540235.5; ENST00000311208.13; ENST00000463128.5; ENST00000590038.1; ENST00000648886.1; ENST00000493253.5
External Link RMBase: m6A_site_362401
mod ID: M6ASITE032444 Click to Show/Hide the Full List
mod site chr17:41622140-41622141:- [5]
Sequence TGCTTCTCTGTACACAAGGAACCTCCCAGGGGCCTGCAGAG
Motif Score 2.930744048
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000577817.3; ENST00000493253.5; ENST00000311208.13; ENST00000648886.1; ENST00000463128.5; ENST00000540235.5; ENST00000590038.1
External Link RMBase: m6A_site_362402
mod ID: M6ASITE032445 Click to Show/Hide the Full List
mod site chr17:41622179-41622180:- [5]
Sequence GGGTCCAGTGTGCAGGGCAGACTCCTCTTTGTACCACACTG
Motif Score 3.319380952
Cell/Tissue List HeLa; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000577817.3; ENST00000648886.1; ENST00000540235.5; ENST00000493253.5; ENST00000463128.5; ENST00000590038.1; ENST00000311208.13
External Link RMBase: m6A_site_362403
mod ID: M6ASITE032446 Click to Show/Hide the Full List
mod site chr17:41622364-41622365:- [3]
Sequence GCTGGCCTACCTGAAGAAGAACCACGAGGAGGTGAGGTGGC
Motif Score 2.930744048
Cell/Tissue List HeLa; HepG2; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000590038.1; ENST00000577817.3; ENST00000648886.1; ENST00000311208.13; ENST00000463128.5; ENST00000493253.5; ENST00000540235.5
External Link RMBase: m6A_site_362404
mod ID: M6ASITE032447 Click to Show/Hide the Full List
mod site chr17:41622397-41622398:- [3]
Sequence CCTGGAGATGCAGATTGAGAACCTCAAGGAGGAGCTGGCCT
Motif Score 2.930744048
Cell/Tissue List HeLa; HepG2; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000311208.13; ENST00000540235.5; ENST00000493253.5; ENST00000590038.1; ENST00000577817.3; ENST00000648886.1; ENST00000463128.5
External Link RMBase: m6A_site_362405
mod ID: M6ASITE032448 Click to Show/Hide the Full List
mod site chr17:41622503-41622504:- [3]
Sequence ATTCCCACGGCAGGTTTGAGACAGAGCAGGCCCTGCGCCTG
Motif Score 2.897386905
Cell/Tissue List HeLa; HepG2; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000311208.13; ENST00000648886.1; ENST00000540235.5; ENST00000577817.3; ENST00000590038.1; ENST00000463128.5; ENST00000493253.5
External Link RMBase: m6A_site_362406
mod ID: M6ASITE032449 Click to Show/Hide the Full List
mod site chr17:41623012-41623013:- [4]
Sequence GATCCTCACAGCCACCGTGGACAATGCCAACATCCTGCTAC
Motif Score 3.643047619
Cell/Tissue List endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000463128.5; ENST00000590038.1; ENST00000577817.3; ENST00000491673.1; ENST00000493253.5; ENST00000311208.13; ENST00000540235.5; ENST00000648886.1
External Link RMBase: m6A_site_362407
mod ID: M6ASITE032450 Click to Show/Hide the Full List
mod site chr17:41624081-41624082:- [3]
Sequence GACAATTGAGGAGCTGCAGAACAAGGTAGGGCCTGCTGGTG
Motif Score 2.951386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000463128.5; ENST00000493253.5; ENST00000311208.13; ENST00000491673.1; ENST00000648886.1; ENST00000577817.3; ENST00000540235.5
External Link RMBase: m6A_site_362408
mod ID: M6ASITE032451 Click to Show/Hide the Full List
mod site chr17:41624100-41624101:- [3]
Sequence ACTACAGCCAGTACTACAGGACAATTGAGGAGCTGCAGAAC
Motif Score 3.643047619
Cell/Tissue List HeLa; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000463128.5; ENST00000577817.3; ENST00000648886.1; ENST00000311208.13; ENST00000540235.5; ENST00000491673.1; ENST00000493253.5
External Link RMBase: m6A_site_362409
mod ID: M6ASITE032452 Click to Show/Hide the Full List
mod site chr17:41624210-41624211:- [3]
Sequence CCGCCTGGCCTCCTACCTGGACAAGGTGCGTGCCCTGGAGG
Motif Score 3.643047619
Cell/Tissue List HeLa; HepG2; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000540235.5; ENST00000311208.13; ENST00000491673.1; ENST00000493253.5; ENST00000463128.5; ENST00000577817.3; ENST00000648886.1
External Link RMBase: m6A_site_362410
mod ID: M6ASITE032453 Click to Show/Hide the Full List
mod site chr17:41624240-41624241:- [3]
Sequence TGAGAAGGCCACCATGCAGAACCTCAATGACCGCCTGGCCT
Motif Score 2.930744048
Cell/Tissue List HeLa; HepG2; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000491673.1; ENST00000648886.1; ENST00000311208.13; ENST00000493253.5; ENST00000540235.5; ENST00000463128.5; ENST00000577817.3
External Link RMBase: m6A_site_362411
mod ID: M6ASITE032454 Click to Show/Hide the Full List
mod site chr17:41624588-41624589:- [3]
Sequence CCTATAAAGGAAGCGGGCGAACCCCGGCAGCCCTACACAAC
Motif Score 2.930744048
Cell/Tissue List HeLa; HepG2
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000648886.1; ENST00000463128.5
External Link RMBase: m6A_site_362412
mod ID: M6ASITE032455 Click to Show/Hide the Full List
mod site chr17:41624651-41624652:- [3]
Sequence GAAAGCCCAGGGGAATGGAAACAGAGGAGCAAGCCTGTTGT
Motif Score 2.20572619
Cell/Tissue List HeLa; HepG2
Seq Type List m6A-seq
Transcript ID List ENST00000648886.1; ENST00000463128.5
External Link RMBase: m6A_site_362413