General Information of the m6A Target Gene (ID: M6ATAR00909)
Target Name Circ_AFF2
Gene Name Circ_AFF2
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator
Histone modification
m6A Regulator: YTH domain-containing family protein 2 (YTHDF2)
In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03350
Epigenetic Regulator Histone acetyltransferase p300 (P300)
Regulated Target Histone H3 lysine 18 lactylation (H3K18la)
Crosstalk relationship Histone modification → m6A
Disease Colorectal cancer
m6A Regulator: RNA demethylase ALKBH5 (ALKBH5)
In total 2 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03362
Epigenetic Regulator Histone deacetylase 2 (HDAC2)
Regulated Target Histone H3 lysine 27 acetylation (H3K27ac)
Crosstalk relationship Histone modification → m6A
Disease Colorectal cancer
Crosstalk ID: M6ACROT03458
Epigenetic Regulator Histone deacetylase 1 (HDAC1)
Regulated Target Histone H3 lysine 27 acetylation (H3K27ac)
Crosstalk relationship Histone modification → m6A
Disease Colorectal cancer
Non-coding RNA
m6A Regulator: YTH domain-containing family protein 2 (YTHDF2)
In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05683
Epigenetic Regulator Circ_AFF2
Regulated Target Cullin associated and neddylation dissociated 1 (CAND1)
Crosstalk relationship m6A → ncRNA
Disease Colorectal cancer
m6A Regulator: RNA demethylase ALKBH5 (ALKBH5)
In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05684
Epigenetic Regulator Circ_AFF2
Regulated Target Cullin associated and neddylation dissociated 1 (CAND1)
Crosstalk relationship m6A → ncRNA
Disease Colorectal cancer
References
Ref 1 Treatment with autologous antigen-presenting cells activated with the HER-2 based antigen Lapuleucel-T: results of a phase I study in immunologic and clinical activity in HER-2 overexpressing breast cancer. J Clin Oncol. 2007 Aug 20;25(24):3680-7. doi: 10.1200/JCO.2006.10.5718.