m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00893)

Target Name	Segment polarity protein dishevelled homolog DVL-2 (DVL2)
Synonyms	Dishevelled-2; DSH homolog 2 Click to Show/Hide
Gene Name	DVL2
Chromosomal Location	17p13.1
Family	DSH family
Function	Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Click to Show/Hide
Gene ID	1856
Uniprot ID	DVL2_HUMAN
HGNC ID	HGNC:3086
KEGG ID	hsa:1856

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00893)

Segment polarity protein dishevelled homolog DVL-2 (DVL2)

5-methylcytidine (m5C)

In total 5 m6A sequence/site(s) in this target gene
mod ID: M5CSITE000934		Click to Show/Hide the Full List
mod site	chr17:7228009-7228010:-		[2]
Sequence	CTGTGGCCAAGTGCTGGGATCCCTCTCCTCAGGCCTATTTC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000575086.1; ENST00000575458.5; ENST00000576840.5; ENST00000575756.5; ENST00000573354.1; ENST00000576285.1; ENST00000574143.1; ENST00000005340.10
External Link	RMBase: m5C_site_17841
mod ID: M5CSITE000935		Click to Show/Hide the Full List
mod site	chr17:7229920-7229921:-		[3]
Sequence	GGGGGCCACAGGACTGGTGGCCCCTCAAGGCTGGAGCGCCA
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000575756.5; ENST00000572285.5; ENST00000576439.1; ENST00000575458.5; ENST00000574143.1; ENST00000574642.5; ENST00000005340.10
External Link	RMBase: m5C_site_17842
mod ID: M5CSITE000936		Click to Show/Hide the Full List
mod site	chr17:7229934-7229935:-		[3]
Sequence	GTCCATATGTAGCTGGGGGCCACAGGACTGGTGGCCCCTCA
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000572285.5; ENST00000575458.5; ENST00000575756.5; ENST00000576439.1; ENST00000574143.1; ENST00000005340.10; ENST00000574642.5
External Link	RMBase: m5C_site_17843
mod ID: M5CSITE000937		Click to Show/Hide the Full List
mod site	chr17:7229935-7229936:-		[3]
Sequence	TGTCCATATGTAGCTGGGGGCCACAGGACTGGTGGCCCCTC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000574642.5; ENST00000575756.5; ENST00000576439.1; ENST00000574143.1; ENST00000575458.5; ENST00000005340.10; ENST00000572285.5
External Link	RMBase: m5C_site_17844
mod ID: M5CSITE000938		Click to Show/Hide the Full List
mod site	chr17:7234458-7234459:-
Sequence	CGCGCGGCGGCCGCTGAGACCGGGGCTTTGAGTCGCACCCC
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000005340.10; ENST00000576949.1
External Link	RMBase: m5C_site_17845

N6-methyladenosine (m6A)

In total 46 m6A sequence/site(s) in this target gene
mod ID: M6ASITE029919		Click to Show/Hide the Full List
mod site	chr17:7225369-7225370:-		[4]
Sequence	ATTTTAGTCACTTGTATAAAACACCAAATAAAGCAATAGAG
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000005340.10
External Link	RMBase: m6A_site_345506
mod ID: M6ASITE029920		Click to Show/Hide the Full List
mod site	chr17:7225603-7225604:-		[5]
Sequence	GAGTTTCTTACATTTTTGGGACTTTTTTAATAGGCATTTCC
Motif Score	4.065041667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000575458.5; ENST00000005340.10
External Link	RMBase: m6A_site_345507
mod ID: M6ASITE029921		Click to Show/Hide the Full List
mod site	chr17:7225614-7225615:-		[5]
Sequence	GGGTTAAAATAGAGTTTCTTACATTTTTGGGACTTTTTTAA
Motif Score	2.07285119
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000005340.10; ENST00000575458.5
External Link	RMBase: m6A_site_345508
mod ID: M6ASITE029922		Click to Show/Hide the Full List
mod site	chr17:7225685-7225686:-		[4]
Sequence	CCCCCTTCCCTCAGGGGTAGACAAGGGACCTTTGATTATTT
Motif Score	2.897386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000575458.5; ENST00000005340.10
External Link	RMBase: m6A_site_345509
mod ID: M6ASITE029924		Click to Show/Hide the Full List
mod site	chr17:7225910-7225911:-		[4]
Sequence	AGCCAGCCGCCAAAGCTTCCACATGGCCATGGGCAATCCCA
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000005340.10; ENST00000575458.5
External Link	RMBase: m6A_site_345510
mod ID: M6ASITE029925		Click to Show/Hide the Full List
mod site	chr17:7225936-7225937:-		[6]
Sequence	CTGGGCTCTGTGCCCCCAGAACTGACAGCCAGCCGCCAAAG
Motif Score	3.373380952
Cell/Tissue List	HeLa; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000575458.5; ENST00000005340.10
External Link	RMBase: m6A_site_345511
mod ID: M6ASITE029926		Click to Show/Hide the Full List
mod site	chr17:7225958-7225959:-		[7]
Sequence	GGGGGCCCCTCCAGTCAGAGACCTGGGCTCTGTGCCCCCAG
Motif Score	2.876744048
Cell/Tissue List	HepG2; HeLa; MM6; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000005340.10; ENST00000575458.5
External Link	RMBase: m6A_site_345512
mod ID: M6ASITE029927		Click to Show/Hide the Full List
mod site	chr17:7226045-7226046:-		[4]
Sequence	CCCTGGCATGGCCCTCCCCTACAACCCCATGATGGTGGTCA
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000005340.10; ENST00000575458.5
External Link	RMBase: m6A_site_345513
mod ID: M6ASITE029928		Click to Show/Hide the Full List
mod site	chr17:7226071-7226072:-		[8]
Sequence	CCAGGGCTCCATCCCTATGGACCGCCCCCTGGCATGGCCCT
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; A549; MM6; peripheral-blood; HEK293T; HEC-1-A; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000575458.5; ENST00000005340.10
External Link	RMBase: m6A_site_345514
mod ID: M6ASITE029929		Click to Show/Hide the Full List
mod site	chr17:7226157-7226158:-		[8]
Sequence	GGGGTGGGGAAGCAAGTGGGACTAGCGATGGGGGCCCTCCT
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; A549; MM6; peripheral-blood; HEK293T; endometrial; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000575458.5; ENST00000005340.10; ENST00000575086.1
External Link	RMBase: m6A_site_345515
mod ID: M6ASITE029930		Click to Show/Hide the Full List
mod site	chr17:7226292-7226293:-		[4]
Sequence	GCAGCCGGAGCAGTGGGTCGACACGGAGTGATGGGGGGGCA
Motif Score	2.865571429
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000575458.5; ENST00000005340.10; ENST00000575086.1
External Link	RMBase: m6A_site_345516
mod ID: M6ASITE029931		Click to Show/Hide the Full List
mod site	chr17:7226461-7226462:-		[4]
Sequence	CTACCATGAGCTTTCATCTTACACCTATGGTGGGGGCAGTG
Motif Score	2.07285119
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000575086.1; ENST00000575458.5; ENST00000005340.10
External Link	RMBase: m6A_site_345517
mod ID: M6ASITE029932		Click to Show/Hide the Full List
mod site	chr17:7226508-7226509:-		[4]
Sequence	TCCTACCAATACCCTGCCCCACACCCCTACAGCCCGCAGCC
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000005340.10; ENST00000575086.1; ENST00000575458.5
External Link	RMBase: m6A_site_345518
mod ID: M6ASITE029933		Click to Show/Hide the Full List
mod site	chr17:7226614-7226615:-		[4]
Sequence	AGTCAACCTGTCTCTCAATGACAACGATGGCTCCAGTGGGG
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000575086.1; ENST00000005340.10; ENST00000575458.5
External Link	RMBase: m6A_site_345519
mod ID: M6ASITE029934		Click to Show/Hide the Full List
mod site	chr17:7227154-7227155:-		[4]
Sequence	CCTGATCCGACACACCGTCAACAAGATCACCTTCTCTGAGC
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000575086.1; ENST00000576840.5; ENST00000571745.1; ENST00000575458.5; ENST00000005340.10
External Link	RMBase: m6A_site_345520
mod ID: M6ASITE029935		Click to Show/Hide the Full List
mod site	chr17:7227444-7227445:-		[8]
Sequence	GTCTGGACTGGAAGTCCGGGACCGCATGTGGCTCAAGATCA
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000576285.1; ENST00000575458.5; ENST00000576840.5; ENST00000005340.10; ENST00000575086.1; ENST00000571745.1
External Link	RMBase: m6A_site_345521
mod ID: M6ASITE029936		Click to Show/Hide the Full List
mod site	chr17:7227458-7227459:-		[8]
Sequence	ATGGCAGCTCCAGAGTCTGGACTGGAAGTCCGGGACCGCAT
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000575458.5; ENST00000571745.1; ENST00000576840.5; ENST00000576285.1; ENST00000575086.1; ENST00000005340.10
External Link	RMBase: m6A_site_345522
mod ID: M6ASITE029937		Click to Show/Hide the Full List
mod site	chr17:7227501-7227502:-		[8]
Sequence	GGGTCTCTCCGTCCATACGGACATGGCATCGGTGACCAAGG
Motif Score	3.643047619
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000005340.10; ENST00000575458.5; ENST00000576285.1; ENST00000575086.1; ENST00000571745.1; ENST00000576840.5
External Link	RMBase: m6A_site_345523
mod ID: M6ASITE029938		Click to Show/Hide the Full List
mod site	chr17:7227678-7227679:-		[4]
Sequence	CCTCCTCCATGAGCACCATTACATCTGGATCGTCTTTGCCT
Motif Score	2.07285119
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000576840.5; ENST00000575086.1; ENST00000571745.1; ENST00000576285.1; ENST00000005340.10; ENST00000575458.5
External Link	RMBase: m6A_site_345524
mod ID: M6ASITE029939		Click to Show/Hide the Full List
mod site	chr17:7227820-7227821:-		[8]
Sequence	GACTGGGCTGGCTTTTGGGGACTGAGAATGGGTCATTTTGG
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000576840.5; ENST00000575086.1; ENST00000005340.10; ENST00000576285.1; ENST00000571745.1; ENST00000575458.5
External Link	RMBase: m6A_site_345525
mod ID: M6ASITE029940		Click to Show/Hide the Full List
mod site	chr17:7228060-7228061:-		[8]
Sequence	TCCCCTGCGCCCTTGACTGGACTTCTCTTCCCCATAGCCCC
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000574143.1; ENST00000576285.1; ENST00000573354.1; ENST00000575458.5; ENST00000005340.10; ENST00000575086.1; ENST00000575756.5
External Link	RMBase: m6A_site_345526
mod ID: M6ASITE029941		Click to Show/Hide the Full List
mod site	chr17:7228106-7228107:-		[8]
Sequence	TTAATCCATCCTTGCTTCAGACCCCCGCCCTCCTGAGGCCT
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000575086.1; ENST00000575756.5; ENST00000574143.1; ENST00000575458.5; ENST00000573354.1; ENST00000005340.10; ENST00000576285.1
External Link	RMBase: m6A_site_345527
mod ID: M6ASITE029942		Click to Show/Hide the Full List
mod site	chr17:7228977-7228978:-		[4]
Sequence	GGTGCTGAGGGACATTGTGCACAAGCCTGGGTGAGTTGCCA
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000577154.1; ENST00000575756.5; ENST00000005340.10; ENST00000574591.1; ENST00000574143.1; ENST00000575458.5; ENST00000573354.1; ENST00000575086.1
External Link	RMBase: m6A_site_345528
mod ID: M6ASITE029943		Click to Show/Hide the Full List
mod site	chr17:7228986-7228987:-		[9]
Sequence	CGCTGTGCGGGTGCTGAGGGACATTGTGCACAAGCCTGGGT
Motif Score	3.643047619
Cell/Tissue List	kidney
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000574143.1; ENST00000575756.5; ENST00000577154.1; ENST00000575458.5; ENST00000574591.1; ENST00000575086.1; ENST00000573354.1; ENST00000005340.10
External Link	RMBase: m6A_site_345529
mod ID: M6ASITE029944		Click to Show/Hide the Full List
mod site	chr17:7229022-7229023:-		[10]
Sequence	GAATGACATGAACTTTGAGAACATGAGCAACGATGACGCTG
Motif Score	2.951386905
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000577154.1; ENST00000574591.1; ENST00000005340.10; ENST00000575086.1; ENST00000575458.5; ENST00000575756.5; ENST00000573354.1; ENST00000574143.1
External Link	RMBase: m6A_site_345530
mod ID: M6ASITE029945		Click to Show/Hide the Full List
mod site	chr17:7229031-7229032:-		[10]
Sequence	CTTCCAGGTGAATGACATGAACTTTGAGAACATGAGCAACG
Motif Score	3.373380952
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000575458.5; ENST00000575086.1; ENST00000575756.5; ENST00000574591.1; ENST00000574143.1; ENST00000577154.1; ENST00000573354.1; ENST00000005340.10
External Link	RMBase: m6A_site_345531
mod ID: M6ASITE029946		Click to Show/Hide the Full List
mod site	chr17:7229147-7229148:-		[4]
Sequence	CGGGCGCATTGAGCCAGGGGACATGCTTTTGCAGGTGTGCT
Motif Score	3.643047619
Cell/Tissue List	hESC-HEK293T; endometrial
Seq Type List	MAZTER-seq; m6A-seq
Transcript ID List	ENST00000574143.1; ENST00000577154.1; ENST00000573354.1; ENST00000575458.5; ENST00000575756.5; ENST00000574591.1; ENST00000005340.10
External Link	RMBase: m6A_site_345532
mod ID: M6ASITE029947		Click to Show/Hide the Full List
mod site	chr17:7229207-7229208:-		[4]
Sequence	GCGGGGAGACGGAGGCATCTACATTGGCTCCATCATGAAGG
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000005340.10; ENST00000575458.5; ENST00000574143.1; ENST00000574642.5; ENST00000577154.1; ENST00000573354.1; ENST00000574591.1; ENST00000575756.5
External Link	RMBase: m6A_site_345533
mod ID: M6ASITE029948		Click to Show/Hide the Full List
mod site	chr17:7229267-7229268:-		[4]
Sequence	GCCTCTCTCCACAGAGAAGTACAACTTCCTGGGTATCTCCA
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000575756.5; ENST00000005340.10; ENST00000575458.5; ENST00000574591.1; ENST00000577154.1; ENST00000574642.5; ENST00000574143.1
External Link	RMBase: m6A_site_345534
mod ID: M6ASITE029949		Click to Show/Hide the Full List
mod site	chr17:7229382-7229383:-		[8]
Sequence	TATCATCACAGTCACGCTAAACATGGGTATGGGGAGAGCCT
Motif Score	2.20572619
Cell/Tissue List	HeLa; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000575458.5; ENST00000575756.5; ENST00000574143.1; ENST00000577154.1; ENST00000572285.5; ENST00000574591.1; ENST00000574642.5; ENST00000005340.10
External Link	RMBase: m6A_site_345535
mod ID: M6ASITE029950		Click to Show/Hide the Full List
mod site	chr17:7229514-7229515:-		[8]
Sequence	TTGGTTTGGGCGGTGCCAGGACACCGGCAGCACCCCAGGGT
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000575458.5; ENST00000574642.5; ENST00000572285.5; ENST00000575756.5; ENST00000574143.1; ENST00000005340.10
External Link	RMBase: m6A_site_345536
mod ID: M6ASITE029951		Click to Show/Hide the Full List
mod site	chr17:7229819-7229820:-		[8]
Sequence	GGGGGACTCGGACGAGGAGGACACCATGAGCAGGTGTGGCT
Motif Score	3.643047619
Cell/Tissue List	HeLa; hESC-HEK293T; peripheral-blood; endometrial; HEC-1-A
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000572285.5; ENST00000575458.5; ENST00000574143.1; ENST00000005340.10; ENST00000576439.1; ENST00000574642.5; ENST00000575756.5
External Link	RMBase: m6A_site_345537
mod ID: M6ASITE029952		Click to Show/Hide the Full List
mod site	chr17:7229834-7229835:-		[8]
Sequence	GGAGAGTACCAGCCTGGGGGACTCGGACGAGGAGGACACCA
Motif Score	4.065041667
Cell/Tissue List	HeLa; peripheral-blood; HEK293T; endometrial; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000005340.10; ENST00000574143.1; ENST00000576439.1; ENST00000575756.5; ENST00000575458.5; ENST00000572285.5; ENST00000574642.5
External Link	RMBase: m6A_site_345538
mod ID: M6ASITE029953		Click to Show/Hide the Full List
mod site	chr17:7229928-7229929:-		[8]
Sequence	ATGTAGCTGGGGGCCACAGGACTGGTGGCCCCTCAAGGCTG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T; endometrial; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000005340.10; ENST00000572285.5; ENST00000576439.1; ENST00000575756.5; ENST00000574642.5; ENST00000575458.5; ENST00000574143.1
External Link	RMBase: m6A_site_345539
mod ID: M6ASITE029954		Click to Show/Hide the Full List
mod site	chr17:7230005-7230006:-		[8]
Sequence	GCCGGGAAGGGCTGGGCCAGACCCCAGCCTTGGTGGGGTGA
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000576439.1; ENST00000575756.5; ENST00000575458.5; ENST00000574642.5; ENST00000574143.1; ENST00000005340.10; ENST00000572285.5
External Link	RMBase: m6A_site_345540
mod ID: M6ASITE029955		Click to Show/Hide the Full List
mod site	chr17:7230062-7230063:-		[8]
Sequence	GGAGCGGCCTCGCAGGAGAGACAGCAGTGAGCATGGCGGTG
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000574642.5; ENST00000575458.5; ENST00000574143.1; ENST00000572285.5; ENST00000576439.1; ENST00000575756.5; ENST00000005340.10
External Link	RMBase: m6A_site_345541
mod ID: M6ASITE029956		Click to Show/Hide the Full List
mod site	chr17:7230108-7230109:-		[8]
Sequence	ATCTGGAGCCTGAGACAGAAACCGAGTCAGTAGTGTCACTG
Motif Score	2.185083333
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000574642.5; ENST00000575458.5; ENST00000574143.1; ENST00000575756.5; ENST00000576439.1; ENST00000572285.5; ENST00000005340.10
External Link	RMBase: m6A_site_345542
mod ID: M6ASITE029957		Click to Show/Hide the Full List
mod site	chr17:7230114-7230115:-		[8]
Sequence	ATGAGAATCTGGAGCCTGAGACAGAAACCGAGTCAGTAGTG
Motif Score	2.897386905
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000005340.10; ENST00000576439.1; ENST00000574143.1; ENST00000572285.5; ENST00000574642.5; ENST00000575458.5; ENST00000575756.5
External Link	RMBase: m6A_site_345543
mod ID: M6ASITE029958		Click to Show/Hide the Full List
mod site	chr17:7230305-7230306:-		[8]
Sequence	GAGGACCAGCGGCATTGGGGACTCAAGGCCTCCATCCTTCC
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000574143.1; ENST00000572285.5; ENST00000005340.10; ENST00000575458.5; ENST00000576949.1; ENST00000576439.1; ENST00000575756.5; ENST00000574642.5
External Link	RMBase: m6A_site_345544
mod ID: M6ASITE029959		Click to Show/Hide the Full List
mod site	chr17:7230321-7230322:-		[8]
Sequence	CTCCTTTGCCACCCGAGAGGACCAGCGGCATTGGGGACTCA
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000574143.1; ENST00000574642.5; ENST00000005340.10; ENST00000576439.1; ENST00000575458.5; ENST00000576949.1; ENST00000575756.5; ENST00000572285.5
External Link	RMBase: m6A_site_345545
mod ID: M6ASITE029960		Click to Show/Hide the Full List
mod site	chr17:7230367-7230368:-		[8]
Sequence	GTCCATGAGCCTCGGGCAGAACTGGCGCCTCCAGCCCCACC
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000005340.10; ENST00000576949.1; ENST00000572285.5; ENST00000575458.5; ENST00000574143.1; ENST00000574642.5; ENST00000575756.5; ENST00000576439.1
External Link	RMBase: m6A_site_345546
mod ID: M6ASITE029961		Click to Show/Hide the Full List
mod site	chr17:7230770-7230771:-		[4]
Sequence	GAAGGAAGAAATTTCAGATGACAACGCCCGCCTCCCCTGCT
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000574143.1; ENST00000572285.5; ENST00000575756.5; ENST00000576949.1; ENST00000005340.10; ENST00000575458.5; ENST00000576439.1
External Link	RMBase: m6A_site_345547
mod ID: M6ASITE029962		Click to Show/Hide the Full List
mod site	chr17:7234045-7234046:-		[11]
Sequence	GAGCGCAAGGCCTAGATAGGACCGGCGGGGGCTTTGCTAGA
Motif Score	3.622404762
Cell/Tissue List	CD34; HEK293T
Seq Type List	m6A-seq
Transcript ID List	ENST00000575756.5; ENST00000576949.1; ENST00000575458.5; ENST00000005340.10; ENST00000572285.5; ENST00000574143.1
External Link	RMBase: m6A_site_345548
mod ID: M6ASITE029963		Click to Show/Hide the Full List
mod site	chr17:7234189-7234190:-		[8]
Sequence	ACCACCTGGATGAGGAAGAGACTCCCTACCTGGTGAAGATC
Motif Score	3.319380952
Cell/Tissue List	HeLa; CD34; U2OS; GSC-11; HEK293T; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000575458.5; ENST00000575756.5; ENST00000576949.1; ENST00000572285.5; ENST00000005340.10
External Link	RMBase: m6A_site_345549
mod ID: M6ASITE029964		Click to Show/Hide the Full List
mod site	chr17:7234264-7234265:-		[8]
Sequence	CCCGGGAGCGCGCGGGCGAGACCATGGCGGGTAGCAGCACT
Motif Score	2.876744048
Cell/Tissue List	HeLa; U2OS
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000575458.5; ENST00000576949.1; ENST00000575756.5; ENST00000005340.10
External Link	RMBase: m6A_site_345550
mod ID: M6ASITE029965		Click to Show/Hide the Full List
mod site	chr17:7234460-7234461:-		[8]
Sequence	GGCGCGCGGCGGCCGCTGAGACCGGGGCTTTGAGTCGCACC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq
Transcript ID List	ENST00000576949.1; ENST00000005340.10
External Link	RMBase: m6A_site_345551

Ref 1	Clinical pipeline report, company report or official report of Sumitomo Dainippon Pharma.
Ref 2	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 3	Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6784-6789. doi: 10.1073/pnas.1817334116. Epub 2019 Mar 14.
Ref 4	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 5	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 6	N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 2;505(7481):117-20. doi: 10.1038/nature12730. Epub 2013 Nov 27.
Ref 7	Efficacy of MEK inhibition in patients with histiocytic neoplasms. Nature. 2019 Mar;567(7749):521-524. doi: 10.1038/s41586-019-1012-y. Epub 2019 Mar 13.
Ref 8	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 9	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 10	m(6)A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018 Sep;20(9):1074-1083. doi: 10.1038/s41556-018-0174-4. Epub 2018 Aug 27.
Ref 11	Suppression of m(6)A reader Ythdf2 promotes hematopoietic stem cell expansion. Cell Res. 2018 Sep;28(9):904-917. doi: 10.1038/s41422-018-0072-0. Epub 2018 Jul 31.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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