m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00831)

Target Name	Homeobox protein Hox-C10 (HOXC10)
Synonyms	Homeobox protein Hox-3I Click to Show/Hide
Gene Name	HOXC10
Chromosomal Location	12q13.13
Family	Abd-B homeobox family
Function	Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Click to Show/Hide
Gene ID	3226
Uniprot ID	HXC10_HUMAN
HGNC ID	HGNC:5122
KEGG ID	hsa:3226

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00831)

Homeobox protein Hox-C10 (HOXC10)

N6-methyladenosine (m6A)

In total 36 m6A sequence/site(s) in this target gene
mod ID: M6ASITE013002		Click to Show/Hide the Full List
mod site	chr12:53985243-53985244:+		[2]
Sequence	TGTAGTATTGCTCCTTAAAAACCCCTCTCTCTGAAAATGAC
Motif Score	2.185083333
Cell/Tissue List	HeLa; HEK293T; Huh7; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000515593.1; ENST00000303460.5
External Link	RMBase: m6A_site_190781
mod ID: M6ASITE013003		Click to Show/Hide the Full List
mod site	chr12:53985262-53985263:+		[3]
Sequence	AACCCCTCTCTCTGAAAATGACATGCCCTCGCAATGTAACT
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000515593.1; ENST00000303460.5
External Link	RMBase: m6A_site_190782
mod ID: M6ASITE013004		Click to Show/Hide the Full List
mod site	chr12:53985287-53985288:+		[2]
Sequence	CCCTCGCAATGTAACTCCGAACTCGTACGCGGAGCCCTTGG
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T; Huh7; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000515593.1; ENST00000303460.5
External Link	RMBase: m6A_site_190783
mod ID: M6ASITE013005		Click to Show/Hide the Full List
mod site	chr12:53985458-53985459:+		[3]
Sequence	CAGCCCCAGCCTCGCCCTCAACACCTATCCGTCCTACCTCT
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000303460.5; ENST00000515593.1
External Link	RMBase: m6A_site_190784
mod ID: M6ASITE013006		Click to Show/Hide the Full List
mod site	chr12:53985488-53985489:+		[2]
Sequence	GTCCTACCTCTCGCAGCTGGACTCCTGGGGCGACCCCAAAG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T; HepG2; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000515593.1; ENST00000303460.5
External Link	RMBase: m6A_site_190785
mod ID: M6ASITE013007		Click to Show/Hide the Full List
mod site	chr12:53985525-53985526:+		[2]
Sequence	AAAGCCGCCTATCGCCTGGAACAACCTGTTGGCAGGCCGCT
Motif Score	2.951386905
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T; HepG2; MSC
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000303460.5; ENST00000515593.1
External Link	RMBase: m6A_site_190786
mod ID: M6ASITE013008		Click to Show/Hide the Full List
mod site	chr12:53985734-53985735:+		[2]
Sequence	CCCGAGCTACTCCGCGCTGGACAAGACGCCCCACTGTTCTG
Motif Score	3.643047619
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000303460.5; ENST00000515593.1
External Link	RMBase: m6A_site_190787
mod ID: M6ASITE013009		Click to Show/Hide the Full List
mod site	chr12:53985813-53985814:+		[2]
Sequence	AGTCTCAACCCGCGCGCCGAACATCTGGAATCGCCTCAGCT
Motif Score	2.951386905
Cell/Tissue List	HeLa; hESC-HEK293T; Jurkat; GSC-11; NB4
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000303460.5; ENST00000515593.1
External Link	RMBase: m6A_site_190788
mod ID: M6ASITE013010		Click to Show/Hide the Full List
mod site	chr12:53985859-53985860:+		[2]
Sequence	GCAAAGTGAGTTTCCCTGAGACCCCCAAGTCCGACAGCCAG
Motif Score	2.876744048
Cell/Tissue List	HeLa; Huh7; Jurkat; GSC-11; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000513209.1; ENST00000303460.5; ENST00000515593.1
External Link	RMBase: m6A_site_190789
mod ID: M6ASITE013011		Click to Show/Hide the Full List
mod site	chr12:53985880-53985881:+		[2]
Sequence	CCCCCAAGTCCGACAGCCAGACCCCCAGCCCCAATGAAATC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293T; Huh7; Jurkat; GSC-11; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000303460.5; ENST00000515593.1; ENST00000513209.1
External Link	RMBase: m6A_site_190790
mod ID: M6ASITE013012		Click to Show/Hide the Full List
mod site	chr12:53985986-53985987:+		[2]
Sequence	AGCTGCCGACTCCAGCCCAGACACCTCGGATAACGAAGCGA
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T; Huh7; Jurkat; NB4
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000513209.1; ENST00000303460.5
External Link	RMBase: m6A_site_190791
mod ID: M6ASITE013013		Click to Show/Hide the Full List
mod site	chr12:53986667-53986668:+		[2]
Sequence	CTGGCTTGGATGGCGTTGGAACAGGGCATTTGGAATGTTGT
Motif Score	2.951386905
Cell/Tissue List	HeLa; U2OS; Huh7; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000511575.1; ENST00000513413.2; ENST00000303460.5; ENST00000513209.1; ENST00000514415.1
External Link	RMBase: m6A_site_190792
mod ID: M6ASITE013014		Click to Show/Hide the Full List
mod site	chr12:53989186-53989187:+		[2]
Sequence	AGAGGAGATAAAGGCAGAAAACACCACAGGAAATTGGCTGA
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T; U2OS; Huh7; MSC
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000513209.1; ENST00000511575.1; ENST00000514415.1; ENST00000513413.2; ENST00000303460.5
External Link	RMBase: m6A_site_190793
mod ID: M6ASITE013015		Click to Show/Hide the Full List
mod site	chr12:53989242-53989243:+		[4]
Sequence	GGAAGAAGAGGTGCCCCTATACTAAACACCAGACGCTGGAA
Motif Score	2.53247619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000513413.2; ENST00000514415.1; ENST00000513209.1; ENST00000511575.1; ENST00000303460.5
External Link	RMBase: m6A_site_190794
mod ID: M6ASITE013016		Click to Show/Hide the Full List
mod site	chr12:53989247-53989248:+		[2]
Sequence	AAGAGGTGCCCCTATACTAAACACCAGACGCTGGAATTGGA
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T; HepG2; U2OS; A549; H1299; Huh7; HEK293A-TOA; MSC
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000513413.2; ENST00000513209.1; ENST00000303460.5; ENST00000511575.1; ENST00000514415.1
External Link	RMBase: m6A_site_190795
mod ID: M6ASITE013017		Click to Show/Hide the Full List
mod site	chr12:53989326-53989327:+		[2]
Sequence	GCCGCCTGGAGATTAGCAAGACCATTAACCTTACAGACAGA
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293T; HepG2; U2OS; A549; H1299; Huh7; HEK293A-TOA; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000511575.1; ENST00000513209.1; ENST00000513413.2; ENST00000303460.5; ENST00000514415.1
External Link	RMBase: m6A_site_190796
mod ID: M6ASITE013018		Click to Show/Hide the Full List
mod site	chr12:53989338-53989339:+		[4]
Sequence	TTAGCAAGACCATTAACCTTACAGACAGACAAGTCAAAATC
Motif Score	2.07285119
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000513413.2; ENST00000513209.1; ENST00000511575.1; ENST00000514415.1; ENST00000303460.5
External Link	RMBase: m6A_site_190797
mod ID: M6ASITE013019		Click to Show/Hide the Full List
mod site	chr12:53989342-53989343:+		[2]
Sequence	CAAGACCATTAACCTTACAGACAGACAAGTCAAAATCTGGT
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T; HepG2; U2OS; A549; H1299; Huh7; HEK293A-TOA; MSC
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000303460.5; ENST00000511575.1; ENST00000513209.1; ENST00000513413.2; ENST00000514415.1
External Link	RMBase: m6A_site_190798
mod ID: M6ASITE013020		Click to Show/Hide the Full List
mod site	chr12:53989346-53989347:+		[4]
Sequence	ACCATTAACCTTACAGACAGACAAGTCAAAATCTGGTTTCA
Motif Score	2.897386905
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000513413.2; ENST00000511575.1; ENST00000513209.1; ENST00000514415.1; ENST00000303460.5
External Link	RMBase: m6A_site_190799
mod ID: M6ASITE013021		Click to Show/Hide the Full List
mod site	chr12:53989382-53989383:+		[2]
Sequence	TTTCAAAATCGCAGAATGAAACTCAAGAAAATGAACCGAGA
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; U2OS; H1299; Huh7; Jurkat; HEK293A-TOA; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000514415.1; ENST00000511575.1; ENST00000513413.2; ENST00000513209.1; ENST00000303460.5
External Link	RMBase: m6A_site_190800
mod ID: M6ASITE013022		Click to Show/Hide the Full List
mod site	chr12:53989396-53989397:+		[2]
Sequence	AATGAAACTCAAGAAAATGAACCGAGAGAATCGGATCCGGG
Motif Score	2.930744048
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; U2OS; H1299; Huh7; Jurkat; HEK293A-TOA; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000511575.1; ENST00000513209.1; ENST00000303460.5; ENST00000514415.1; ENST00000513413.2
External Link	RMBase: m6A_site_190801
mod ID: M6ASITE013023		Click to Show/Hide the Full List
mod site	chr12:53989418-53989419:+		[2]
Sequence	CGAGAGAATCGGATCCGGGAACTGACCTCCAATTTTAATTT
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; U2OS; H1299; Huh7; Jurkat; HEK293A-TOA; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000513209.1; ENST00000303460.5; ENST00000513413.2; ENST00000511575.1; ENST00000514415.1
External Link	RMBase: m6A_site_190802
mod ID: M6ASITE013024		Click to Show/Hide the Full List
mod site	chr12:53989422-53989423:+		[4]
Sequence	AGAATCGGATCCGGGAACTGACCTCCAATTTTAATTTCACC
Motif Score	2.839113095
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000303460.5; ENST00000513209.1; ENST00000511575.1; ENST00000513413.2; ENST00000514415.1
External Link	RMBase: m6A_site_190803
mod ID: M6ASITE013025		Click to Show/Hide the Full List
mod site	chr12:53989553-53989554:+		[4]
Sequence	CTGAGTATAAATGCAATGCGACTGCAAAAAAGGCAAAGACC
Motif Score	3.287565476
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000511575.1; ENST00000514415.1; ENST00000513209.1; ENST00000303460.5; ENST00000513413.2
External Link	RMBase: m6A_site_190804
mod ID: M6ASITE013026		Click to Show/Hide the Full List
mod site	chr12:53989571-53989572:+		[2]
Sequence	CGACTGCAAAAAAGGCAAAGACCTCAGACTCTCCTTCCAAG
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293T; HepG2; U2OS; A549; H1299; Huh7; peripheral-blood; HEK293A-TOA; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000513413.2; ENST00000513209.1; ENST00000511575.1; ENST00000514415.1; ENST00000303460.5
External Link	RMBase: m6A_site_190805
mod ID: M6ASITE013027		Click to Show/Hide the Full List
mod site	chr12:53989578-53989579:+		[2]
Sequence	AAAAAAGGCAAAGACCTCAGACTCTCCTTCCAAGGGACCTG
Motif Score	3.319380952
Cell/Tissue List	HeLa; HEK293T; HepG2; U2OS; A549; H1299; Huh7; peripheral-blood; HEK293A-TOA; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000513413.2; ENST00000303460.5; ENST00000514415.1; ENST00000511575.1; ENST00000513209.1
External Link	RMBase: m6A_site_190806
mod ID: M6ASITE013028		Click to Show/Hide the Full List
mod site	chr12:53989594-53989595:+		[2]
Sequence	TCAGACTCTCCTTCCAAGGGACCTGTGGTTCGTGCTGCGAA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HEK293T; HepG2; U2OS; A549; Huh7; peripheral-blood; HEK293A-TOA; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000514415.1; ENST00000303460.5; ENST00000511575.1; ENST00000513209.1; ENST00000513413.2
External Link	RMBase: m6A_site_190807
mod ID: M6ASITE013029		Click to Show/Hide the Full List
mod site	chr12:53989953-53989954:+		[2]
Sequence	GCACCCAGAGCCTCCACCAAACCCTCTCCATGTCTTTACCT
Motif Score	2.185083333
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000511575.1; ENST00000303460.5; ENST00000513209.1
External Link	RMBase: m6A_site_190808
mod ID: M6ASITE013030		Click to Show/Hide the Full List
mod site	chr12:53989970-53989971:+		[4]
Sequence	CAAACCCTCTCCATGTCTTTACCTCCCAGTCGCTCTAAGAA
Motif Score	2.052208333
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000511575.1; ENST00000513209.1; ENST00000303460.5
External Link	RMBase: m6A_site_190809
mod ID: M6ASITE013031		Click to Show/Hide the Full List
mod site	chr12:53990014-53990015:+		[4]
Sequence	GCTTGAAGTCTCGTATTTGTACTGCTTTCTGCTTTTCTCCC
Motif Score	3.278136905
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000303460.5; ENST00000513209.1
External Link	RMBase: m6A_site_190810
mod ID: M6ASITE013032		Click to Show/Hide the Full List
mod site	chr12:53990053-53990054:+		[3]
Sequence	CCACCCCTCCTAGCACCCCCACATCCCCCATCTAGTAACAT
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000303460.5; ENST00000513209.1
External Link	RMBase: m6A_site_190811
mod ID: M6ASITE013033		Click to Show/Hide the Full List
mod site	chr12:53990070-53990071:+		[3]
Sequence	CCCACATCCCCCATCTAGTAACATCTCAGAAATTTCATCCA
Motif Score	2.168095238
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000513209.1; ENST00000303460.5
External Link	RMBase: m6A_site_190812
mod ID: M6ASITE013034		Click to Show/Hide the Full List
mod site	chr12:53990096-53990097:+		[2]
Sequence	CAGAAATTTCATCCAGAGGAACAAAAAAATTAAAAATAGAA
Motif Score	2.951386905
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T; Huh7
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000303460.5; ENST00000513209.1
External Link	RMBase: m6A_site_190813
mod ID: M6ASITE013035		Click to Show/Hide the Full List
mod site	chr12:53990116-53990117:+		[2]
Sequence	ACAAAAAAATTAAAAATAGAACATAGCAAAGCAAAGACAGA
Motif Score	2.951386905
Cell/Tissue List	HeLa; HEK293T; Huh7
Seq Type List	m6A-seq; MeRIP-seq; DART-seq
Transcript ID List	ENST00000303460.5; ENST00000513209.1
External Link	RMBase: m6A_site_190814
mod ID: M6ASITE013036		Click to Show/Hide the Full List
mod site	chr12:53990132-53990133:+		[2]
Sequence	TAGAACATAGCAAAGCAAAGACAGAATGCCCCCCCCCCCAA
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; Huh7
Seq Type List	m6A-seq; MeRIP-seq; DART-seq
Transcript ID List	ENST00000303460.5; ENST00000513209.1
External Link	RMBase: m6A_site_190815
mod ID: M6ASITE013037		Click to Show/Hide the Full List
mod site	chr12:53990246-53990247:+		[5]
Sequence	TCCTTAATGGAGAAAAAAAAACCTAATAAATTTCCAGAATC
Motif Score	2.185083333
Cell/Tissue List	HEK293T; Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000303460.5; ENST00000513209.1
External Link	RMBase: m6A_site_190816

N7-methylguanosine (m7G)

In total 1 m6A sequence/site(s) in this target gene
mod ID: m7GSITE000015		Click to Show/Hide the Full List
mod site	chr12:53989219-53989220:+		[6]
Sequence	TTGGCTGACAGCAAAGAGCGGAAGGAAGAAGAGGTGCCCCT
Cell/Tissue List	A549; HeLa; HepG2
Seq Type List	BoRed-seq&m7G-RIP-seq; m7G-seq
Transcript ID List	ENST00000511575.1; ENST00000514415.1; ENST00000513413.2; ENST00000513209.1; ENST00000303460.5
External Link	RMBase: m7G_site_208

Ref 1	ClinicalTrials.gov (NCT03403777) Avelumab in Refractory Testicular Germ Cell Cancer.. U.S. National Institutes of Health.
Ref 2	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 3	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 4	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 5	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.
Ref 6	METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation. Mol Cell. 2019 Jun 20;74(6):1278-1290.e9. doi: 10.1016/j.molcel.2019.03.040. Epub 2019 Apr 25.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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