General Information of the m6A Target Gene (ID: M6ATAR00824)
Target Name
N-myc proto-oncogene protein (MYCN)
Synonyms
Class E basic helix-loop-helix protein 37; bHLHe37
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Gene Name
Mycn
Chromosomal Location
2p24.3
Function
Positively regulates the transcription of MYCNOS in neuroblastoma cells.
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Gene ID
4613
Uniprot ID
MYCN_HUMAN
HGNC ID
HGNC:7559
KEGG ID
hsa:4613
References
Ref 1
US patent application no. 5,965,722, Antisense inhibition of ras gene with chimeric and alternating oligonucleotides.
Ref 2
AZD9291, an irreversible EGFR TKI, overcomes T790M-mediated resistance to EGFR inhibitors in lung cancer. Cancer Discov. 2014 Sep;4(9):1046-61. doi: 10.1158/2159-8290.CD-14-0337. Epub 2014 Jun 3.