m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00794)

Target Name	AC010894.3
Gene Name	AC010894.3
Chromosomal Location	2q31.1
Gene ID	105373748
HGNC ID	HGNC:55827

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

AC010894.3 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

Browse Disease

Ovarian cancer [ICD-11: 2C73]

Disease Info

In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response		[]
Response Summary	In ovarian cancer, a prognostic signature containing four LI-m6As (AC010894.3, ACAP2-IT1, CACNA1G-AS1, and UBA6-AS1) was constructed according to the LASSO Cox regression analysis of the 10 LI-m6As.
Responsed Disease	Ovarian cancer [ICD-11: 2C73]

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00794)

AC010894.3

5-methylcytidine (m5C)

In total 1 m6A sequence/site(s) in this target gene
mod ID: M5CSITE002433		Click to Show/Hide the Full List
mod site	chr2:174719802-174719803:+		[1]
Sequence	AGAAAATGTTGGTATAGGTTCGCAGCCGCCGCCGCGCCGCC
Seq Type List	Bisulfite-seq
Transcript ID List	rmsk_747676; ENST00000442996.1
External Link	RMBase: m5C_site_27493

N6-methyladenosine (m6A)

In total 39 m6A sequence/site(s) in this target gene
mod ID: M6ASITE048271		Click to Show/Hide the Full List
mod site	chr2:174547181-174547182:+		[2]
Sequence	GATCAAGGGAACCTCAACAAACAACCCCAGCCATGGAGGCG
Motif Score	2.20572619
Cell/Tissue List	U2OS
Seq Type List	MeRIP-seq
Transcript ID List	rmsk_747364; ENST00000442996.1
External Link	RMBase: m6A_site_500304
mod ID: M6ASITE048272		Click to Show/Hide the Full List
mod site	chr2:174547217-174547218:+		[2]
Sequence	AGGCGGCGGTGTCTTTGAAGACCCCATGAGAGCATCAAACA
Motif Score	2.876744048
Cell/Tissue List	U2OS
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000442996.1; rmsk_747364
External Link	RMBase: m6A_site_500305
mod ID: M6ASITE048273		Click to Show/Hide the Full List
mod site	chr2:174547235-174547236:+		[2]
Sequence	AGACCCCATGAGAGCATCAAACAAGGGAGAGAGGTAACTTT
Motif Score	2.20572619
Cell/Tissue List	U2OS
Seq Type List	MeRIP-seq
Transcript ID List	rmsk_747364; ENST00000442996.1
External Link	RMBase: m6A_site_500306
mod ID: M6ASITE048274		Click to Show/Hide the Full List
mod site	chr2:174547374-174547375:+		[2]
Sequence	CTTCCTGCTTTGAGCCTGGAACAAATCATGGTAGTAAAATG
Motif Score	2.951386905
Cell/Tissue List	U2OS
Seq Type List	MeRIP-seq
Transcript ID List	rmsk_747364; ENST00000442996.1; ENST00000412835.1
External Link	RMBase: m6A_site_500307
mod ID: M6ASITE048275		Click to Show/Hide the Full List
mod site	chr2:174547468-174547469:+		[3]
Sequence	CTTCAAGAATGAAGCCGCGGACCCTCACGGTGAGTGTTACA
Motif Score	3.622404762
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000412835.1; ENST00000442996.1
External Link	RMBase: m6A_site_500308
mod ID: M6ASITE048276		Click to Show/Hide the Full List
mod site	chr2:174575251-174575252:+		[4]
Sequence	CTTCGGCATTCCAGCCTGGAACAATCCTCCCAGACCTGGAG
Motif Score	2.951386905
Cell/Tissue List	HeLa; H1B; CD4T; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000412835.1; ENST00000454203.1; ENST00000442996.1
External Link	RMBase: m6A_site_500371
mod ID: M6ASITE048277		Click to Show/Hide the Full List
mod site	chr2:174575264-174575265:+		[4]
Sequence	GCCTGGAACAATCCTCCCAGACCTGGAGGTCCGCCCCCTCC
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000454203.1; ENST00000442996.1; ENST00000412835.1
External Link	RMBase: m6A_site_500372
mod ID: M6ASITE048278		Click to Show/Hide the Full List
mod site	chr2:174575288-174575289:+		[4]
Sequence	GGAGGTCCGCCCCCTCCAAAACTTCCACCGCCTCCGCCACC
Motif Score	2.627720238
Cell/Tissue List	HeLa; LCLs
Seq Type List	m6A-seq
Transcript ID List	rmsk_747416; ENST00000454203.1; ENST00000412835.1; ENST00000442996.1
External Link	RMBase: m6A_site_500374
mod ID: M6ASITE048279		Click to Show/Hide the Full List
mod site	chr2:174575394-174575395:+		[4]
Sequence	TAGGTTCTGTAGAAGAAGAGACACCCGACAGACTATGCCCC
Motif Score	2.897386905
Cell/Tissue List	HeLa; LCLs
Seq Type List	m6A-seq
Transcript ID List	ENST00000454203.1; ENST00000442996.1; ENST00000412835.1
External Link	RMBase: m6A_site_500375
mod ID: M6ASITE048280		Click to Show/Hide the Full List
mod site	chr2:174575405-174575406:+		[4]
Sequence	GAAGAAGAGACACCCGACAGACTATGCCCCCTGGTCTGGCC
Motif Score	3.319380952
Cell/Tissue List	HeLa; LCLs
Seq Type List	m6A-seq
Transcript ID List	ENST00000442996.1; ENST00000454203.1; ENST00000412835.1
External Link	RMBase: m6A_site_500376
mod ID: M6ASITE048281		Click to Show/Hide the Full List
mod site	chr2:174587478-174587479:+		[4]
Sequence	CTTTCTGTGAACAGAAATGGACTGGAGAAGCTAAAAAAGAC
Motif Score	4.065041667
Cell/Tissue List	HeLa; LCLs
Seq Type List	m6A-seq
Transcript ID List	ENST00000442996.1; ENST00000412835.1; ENST00000454203.1
External Link	RMBase: m6A_site_500383
mod ID: M6ASITE048282		Click to Show/Hide the Full List
mod site	chr2:174587497-174587498:+		[4]
Sequence	GACTGGAGAAGCTAAAAAAGACACTGCTGGACTTGTCACAG
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000412835.1; ENST00000454203.1; ENST00000442996.1
External Link	RMBase: m6A_site_500384
mod ID: M6ASITE048283		Click to Show/Hide the Full List
mod site	chr2:174587507-174587508:+		[4]
Sequence	GCTAAAAAAGACACTGCTGGACTTGTCACAGCCGCCGGGAA
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000412835.1; ENST00000454203.1; ENST00000442996.1
External Link	RMBase: m6A_site_500385
mod ID: M6ASITE048284		Click to Show/Hide the Full List
mod site	chr2:174587528-174587529:+		[4]
Sequence	CTTGTCACAGCCGCCGGGAAACAAGAATTAAGACAGTTCGG
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000454203.1; ENST00000412835.1; ENST00000442996.1
External Link	RMBase: m6A_site_500386
mod ID: M6ASITE048285		Click to Show/Hide the Full List
mod site	chr2:174587540-174587541:+		[4]
Sequence	GCCGGGAAACAAGAATTAAGACAGTTCGGAAGAGTCCCATT
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000454203.1; ENST00000442996.1; ENST00000412835.1
External Link	RMBase: m6A_site_500387
mod ID: M6ASITE048286		Click to Show/Hide the Full List
mod site	chr2:174655728-174655729:+		[3]
Sequence	CTTCCCAAAGTGCACCCCAGACACCCAACAGTTTTTCCAGC
Motif Score	2.897386905
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000412835.1; ENST00000442996.1; rmsk_747565
External Link	RMBase: m6A_site_500390
mod ID: M6ASITE048287		Click to Show/Hide the Full List
mod site	chr2:174655753-174655754:+		[3]
Sequence	CAACAGTTTTTCCAGCCCAGACTCACCACACTGTGTGGTAA
Motif Score	3.319380952
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	rmsk_747565; ENST00000412835.1; ENST00000442996.1
External Link	RMBase: m6A_site_500391
mod ID: M6ASITE048288		Click to Show/Hide the Full List
mod site	chr2:174655805-174655806:+		[3]
Sequence	CTCAGTTGTGCTCCCCACAGACTATAAGCTCTATGAGGGCA
Motif Score	3.319380952
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000412835.1; rmsk_747565; ENST00000442996.1
External Link	RMBase: m6A_site_500392
mod ID: M6ASITE048289		Click to Show/Hide the Full List
mod site	chr2:174655932-174655933:+		[3]
Sequence	CCATTGGTGGCCTCCAGTGAACCATGTCTTCTGGTATTTAC
Motif Score	2.930744048
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	rmsk_747566; ENST00000442996.1; ENST00000412835.1
External Link	RMBase: m6A_site_500393
mod ID: M6ASITE048290		Click to Show/Hide the Full List
mod site	chr2:174656076-174656077:+		[3]
Sequence	AGCCCTGTGACCTTGCTGAGACCCTGAAGAGACCACATAGA
Motif Score	2.876744048
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000442996.1; ENST00000412835.1; rmsk_747566
External Link	RMBase: m6A_site_500394
mod ID: M6ASITE048291		Click to Show/Hide the Full List
mod site	chr2:174656087-174656088:+		[3]
Sequence	CTTGCTGAGACCCTGAAGAGACCACATAGAGAGGCCACTTG
Motif Score	2.876744048
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000442996.1; ENST00000412835.1; rmsk_747566
External Link	RMBase: m6A_site_500395
mod ID: M6ASITE048292		Click to Show/Hide the Full List
mod site	chr2:174656197-174656198:+		[3]
Sequence	ACCAGATAACTCACTACAAGACTGACCACAGGCAAGAACAG
Motif Score	3.319380952
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	rmsk_747566; ENST00000442996.1; ENST00000412835.1
External Link	RMBase: m6A_site_500396
mod ID: M6ASITE048293		Click to Show/Hide the Full List
mod site	chr2:174656214-174656215:+		[3]
Sequence	AAGACTGACCACAGGCAAGAACAGCAGAAGAGCTGCCCAGC
Motif Score	2.951386905
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	rmsk_747566; ENST00000412835.1; ENST00000442996.1
External Link	RMBase: m6A_site_500397
mod ID: M6ASITE048294		Click to Show/Hide the Full List
mod site	chr2:174665179-174665180:+		[3]
Sequence	ATGGTTTCTCCTTTCAGAGAACTCAGAATGAAGGGGCCTCA
Motif Score	3.373380952
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000442996.1; ENST00000412835.1
External Link	RMBase: m6A_site_500398
mod ID: M6ASITE048295		Click to Show/Hide the Full List
mod site	chr2:174665249-174665250:+		[3]
Sequence	CCTGTTTTACTACGAAGCAAACACCTCGACTATAAGCCGCC
Motif Score	2.20572619
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000442996.1; ENST00000412835.1
External Link	RMBase: m6A_site_500399
mod ID: M6ASITE048296		Click to Show/Hide the Full List
mod site	chr2:174665274-174665275:+		[3]
Sequence	TCGACTATAAGCCGCCATAGACCAGGGTCTGTGTCTCATTC
Motif Score	2.876744048
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000412835.1; ENST00000442996.1
External Link	RMBase: m6A_site_500400
mod ID: M6ASITE048297		Click to Show/Hide the Full List
mod site	chr2:174665303-174665304:+		[3]
Sequence	TGTGTCTCATTCGTGTCTGGACAATGCATCACAGACACTCA
Motif Score	3.643047619
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000412835.1; ENST00000442996.1
External Link	RMBase: m6A_site_500401
mod ID: M6ASITE048298		Click to Show/Hide the Full List
mod site	chr2:174665317-174665318:+		[3]
Sequence	GTCTGGACAATGCATCACAGACACTCAACTGTTTTCTGCCT
Motif Score	2.897386905
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000442996.1; ENST00000412835.1
External Link	RMBase: m6A_site_500402
mod ID: M6ASITE048299		Click to Show/Hide the Full List
mod site	chr2:174665351-174665352:+		[3]
Sequence	TCTGCCTGAGCAGAATTAAGACTTGGCCTCCTAACTCCTCC
Motif Score	3.319380952
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000412835.1; ENST00000442996.1
External Link	RMBase: m6A_site_500403
mod ID: M6ASITE048300		Click to Show/Hide the Full List
mod site	chr2:174665455-174665456:+		[3]
Sequence	AGATTCAAAGAGTAAGGAAAACCATTTCTAGGACCATGAAA
Motif Score	2.185083333
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000442996.1; ENST00000412835.1
External Link	RMBase: m6A_site_500404
mod ID: M6ASITE048301		Click to Show/Hide the Full List
mod site	chr2:174665467-174665468:+		[3]
Sequence	TAAGGAAAACCATTTCTAGGACCATGAAATGTGTCACTGGA
Motif Score	3.622404762
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000412835.1; ENST00000442996.1
External Link	RMBase: m6A_site_500405
mod ID: M6ASITE048302		Click to Show/Hide the Full List
mod site	chr2:174773071-174773072:+		[3]
Sequence	TAGCAAAAAGTATGTCTTGAACTTTTCTTTGTTACACACAG
Motif Score	3.373380952
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000442996.1
External Link	RMBase: m6A_site_500417
mod ID: M6ASITE048303		Click to Show/Hide the Full List
mod site	chr2:174773107-174773108:+		[3]
Sequence	CACAGTCTGGGTAATAACAGACTGAAGGAAAACTAAAGAAG
Motif Score	3.319380952
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000442996.1
External Link	RMBase: m6A_site_500418
mod ID: M6ASITE048304		Click to Show/Hide the Full List
mod site	chr2:174773118-174773119:+		[3]
Sequence	TAATAACAGACTGAAGGAAAACTAAAGAAGCTTGGGAGGCT
Motif Score	2.627720238
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000442996.1
External Link	RMBase: m6A_site_500419
mod ID: M6ASITE048305		Click to Show/Hide the Full List
mod site	chr2:174773160-174773161:+		[3]
Sequence	AGTTCAATGACAAATGAAGAACTAAGGCAGAGAAAAAAGAG
Motif Score	3.373380952
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000442996.1
External Link	RMBase: m6A_site_500420
mod ID: M6ASITE048306		Click to Show/Hide the Full List
mod site	chr2:174773277-174773278:+		[3]
Sequence	AGAGTGGGAGAGGAGTGCAAACATTATTTTTGAGGCGCTTT
Motif Score	2.20572619
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000442996.1
External Link	RMBase: m6A_site_500421
mod ID: M6ASITE048307		Click to Show/Hide the Full List
mod site	chr2:174773541-174773542:+		[3]
Sequence	CTGAGAGGTGCTAACTGTGAACATTGTTATTCACTTGTGTT
Motif Score	2.951386905
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000442996.1
External Link	RMBase: m6A_site_500422
mod ID: M6ASITE048308		Click to Show/Hide the Full List
mod site	chr2:174773594-174773595:+		[3]
Sequence	TTTAATTAGTTTTAATTTGAACCAAGAATGTTCTACTGTTG
Motif Score	2.930744048
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000442996.1
External Link	RMBase: m6A_site_500423
mod ID: M6ASITE048309		Click to Show/Hide the Full List
mod site	chr2:174773617-174773618:+		[3]
Sequence	AAGAATGTTCTACTGTTGAAACTATGTCAAGAATGATCAAA
Motif Score	2.627720238
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000442996.1
External Link	RMBase: m6A_site_500424

Ref 1	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 2	RNA-methylation-dependent RNA processing controls the speed of the circadian clock. Cell. 2013 Nov 7;155(4):793-806. doi: 10.1016/j.cell.2013.10.026.
Ref 3	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.
Ref 4	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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