m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00307)

Target Name	Kinesin-like protein KIF2C (KIF2C)
Synonyms	Kinesin-like protein 6; Mitotic centromere-associated kinesin; MCAK; KNSL6 Click to Show/Hide
Gene Name	KIF2C
Chromosomal Location	1p34.1
Family	TRAFAC class myosin-kinesin ATPase superfamily; Kinesin family; MCAK/KIF2 subfamily
Function	In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis. Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment. Click to Show/Hide
Gene ID	11004
Uniprot ID	KIF2C_HUMAN
HGNC ID	HGNC:6393
KEGG ID	hsa:11004

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

KIF2C can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

Browse Disease

Colorectal cancer [ICD-11: 2B91]

Disease Info

In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response		[]
Response Summary	The study highlights a robust correlation between the level of cancer stemness and traits related to tumor heterogeneity, including the immune microenvironment, TMB, and the expression of m6A RNA methylation regulatory factors in colorectal cancer cells. A three-gene prognostic signature (PARPBP, KNSTRN, and Kinesin-like protein KIF2C (KIF2C)) was explored together with specific clinical features to construct a nomogram, which was successfully validated in an external cohort.
Responsed Disease	Colorectal cancer [ICD-11: 2B91]

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00307)

Kinesin-like protein KIF2C (KIF2C)

N4-acetylcytidine (ac4C)

In total 1 m6A sequence/site(s) in this target gene
mod ID: AC4SITE000228		Click to Show/Hide the Full List
mod site	chr1:44739943-44739944:+		[1]
Sequence	ACTCTCCGAATGGCCATGGACTCGTCGCTTCAGGCCCGCCT
Cell/Tissue List	H1
Seq Type List	ac4C-seq
Transcript ID List	ENST00000452259.5; ENST00000372224.9; ENST00000493027.5
External Link	RMBase: ac4C_site_82

Adenosine-to-Inosine editing (A-to-I)

In total 1 m6A sequence/site(s) in this target gene
mod ID: A2ISITE007285		Click to Show/Hide the Full List
mod site	chr1:44748591-44748592:+		[2]
Sequence	ACTTGGTTGTCCATGCTGGAATACCATGATATGATCGTAGC
Transcript ID List	ENST00000455186.5; ENST00000480574.1; ENST00000372217.5; ENST00000372224.9; ENST00000493027.5; ENST00000452259.5
External Link	RMBase: RNA-editing_site_5036

5-methylcytidine (m5C)

In total 15 m6A sequence/site(s) in this target gene
mod ID: M5CSITE001865		Click to Show/Hide the Full List
mod site	chr1:44747431-44747432:+		[3]
Sequence	ACCCAGAACTCTTACAGCTTCTTCCCTTACATCCGAAGGAC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000372224.9; ENST00000455186.5; ENST00000493027.5; ENST00000480574.1; ENST00000372217.5; ENST00000452259.5
External Link	RMBase: m5C_site_2368
mod ID: M5CSITE001866		Click to Show/Hide the Full List
mod site	chr1:44755517-44755518:+
Sequence	TCGTGATCTGCCCACCTCAGCCTCCCAAAGTGCTGGGATTA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000372224.9; ENST00000493027.5; ENST00000455186.5; ENST00000452259.5; ENST00000372217.5
External Link	RMBase: m5C_site_2369
mod ID: M5CSITE001867		Click to Show/Hide the Full List
mod site	chr1:44755529-44755530:+
Sequence	CACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCC
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000372217.5; ENST00000455186.5; ENST00000372224.9; ENST00000493027.5; ENST00000452259.5
External Link	RMBase: m5C_site_2370
mod ID: M5CSITE001868		Click to Show/Hide the Full List
mod site	chr1:44755538-44755539:+
Sequence	CTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCATGCCC
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000372224.9; ENST00000455186.5; ENST00000452259.5; ENST00000372217.5; ENST00000493027.5
External Link	RMBase: m5C_site_2371
mod ID: M5CSITE001869		Click to Show/Hide the Full List
mod site	chr1:44755549-44755550:+
Sequence	CTGGGATTACAGGCGTGAGCCACCATGCCCAGCCGAGGTTA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000455186.5; ENST00000452259.5; ENST00000372217.5; ENST00000372224.9; ENST00000493027.5
External Link	RMBase: m5C_site_2372
mod ID: M5CSITE001870		Click to Show/Hide the Full List
mod site	chr1:44758061-44758062:+		[3]
Sequence	CCCTCAGCCCGGGACGTCTTCCTCCTGAAGAATCAACCCTG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000372224.9; ENST00000372217.5
External Link	RMBase: m5C_site_2374
mod ID: M5CSITE001871		Click to Show/Hide the Full List
mod site	chr1:44758065-44758066:+		[3]
Sequence	CAGCCCGGGACGTCTTCCTCCTGAAGAATCAACCCTGCTAC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000372224.9; ENST00000372217.5
External Link	RMBase: m5C_site_2375
mod ID: M5CSITE001872		Click to Show/Hide the Full List
mod site	chr1:44765077-44765078:+
Sequence	TATAGTGAGCCGAGATGGTGCCACTGCACTCCAGCCTGGGC
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000372224.9; ENST00000372217.5; ENST00000472235.1; rmsk_103659
External Link	RMBase: m5C_site_2376
mod ID: M5CSITE001873		Click to Show/Hide the Full List
mod site	chr1:44765087-44765088:+
Sequence	CGAGATGGTGCCACTGCACTCCAGCCTGGGCAACAGAGCAA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000372224.9; rmsk_103659; ENST00000472235.1; ENST00000372217.5
External Link	RMBase: m5C_site_2377
mod ID: M5CSITE001874		Click to Show/Hide the Full List
mod site	chr1:44765088-44765089:+
Sequence	GAGATGGTGCCACTGCACTCCAGCCTGGGCAACAGAGCAAG
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000372224.9; rmsk_103659; ENST00000372217.5; ENST00000472235.1
External Link	RMBase: m5C_site_2378
mod ID: M5CSITE001875		Click to Show/Hide the Full List
mod site	chr1:44765091-44765092:+
Sequence	ATGGTGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACT
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9; ENST00000472235.1; rmsk_103659
External Link	RMBase: m5C_site_2379
mod ID: M5CSITE001876		Click to Show/Hide the Full List
mod site	chr1:44766422-44766423:+
Sequence	AGAGTTCGAGATCAGCCTGGCCAACATGGAGAAACCCCGTC
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000372224.9; ENST00000372217.5; ENST00000472235.1; rmsk_103665
External Link	RMBase: m5C_site_2380
mod ID: M5CSITE001877		Click to Show/Hide the Full List
mod site	chr1:44767471-44767472:+		[3]
Sequence	TTCTCAGCATAGAGCTTTCTCCGCAGCATCCTGCCTGCGTG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000372224.9; ENST00000372217.5
External Link	RMBase: m5C_site_2381
mod ID: M5CSITE001878		Click to Show/Hide the Full List
mod site	chr1:44767472-44767473:+		[3]
Sequence	TCTCAGCATAGAGCTTTCTCCGCAGCATCCTGCCTGCGTGG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9
External Link	RMBase: m5C_site_2382
mod ID: M5CSITE001879		Click to Show/Hide the Full List
mod site	chr1:44767599-44767600:+		[3]
Sequence	AACCTTCTACGCCTTTGGGCCGAGCACTGAATGTCTTGTAC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9
External Link	RMBase: m5C_site_2383

N6-methyladenosine (m6A)

In total 61 m6A sequence/site(s) in this target gene
mod ID: M6ASITE022797		Click to Show/Hide the Full List
mod site	chr1:44739838-44739839:+		[4]
Sequence	CGCTTGCGCGCGGGATTTAAACTGCGGCGGTTTACGCGGCG
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293A-TOA; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000493027.5; ENST00000372224.9; ENST00000452259.5
External Link	RMBase: m6A_site_27728
mod ID: M6ASITE022798		Click to Show/Hide the Full List
mod site	chr1:44739864-44739865:+		[4]
Sequence	GCGGTTTACGCGGCGTTAAGACTTCGTAGGGTTAGCGAAAT
Motif Score	3.319380952
Cell/Tissue List	HeLa; MT4; HEK293A-TOA; MSC; TIME; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000493027.5; ENST00000452259.5; ENST00000372224.9
External Link	RMBase: m6A_site_27729
mod ID: M6ASITE022799		Click to Show/Hide the Full List
mod site	chr1:44739942-44739943:+		[4]
Sequence	GACTCTCCGAATGGCCATGGACTCGTCGCTTCAGGCCCGCC
Motif Score	4.065041667
Cell/Tissue List	HeLa; MT4; peripheral-blood; MSC; TIME; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000493027.5; ENST00000372224.9; ENST00000452259.5
External Link	RMBase: m6A_site_27730
mod ID: M6ASITE022800		Click to Show/Hide the Full List
mod site	chr1:44740031-44740032:+		[4]
Sequence	GGGGTCCCTAGGTCAAGGGGACTCGTGAGCGGTGAGACGAC
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000452259.5; ENST00000455186.5; ENST00000493027.5; ENST00000372224.9
External Link	RMBase: m6A_site_27731
mod ID: M6ASITE022801		Click to Show/Hide the Full List
mod site	chr1:44740938-44740939:+		[4]
Sequence	TTCACAGTGCCAATGTAAGGACTGTGAACTTGGAGAAATCC
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000455186.5; ENST00000493027.5; ENST00000372224.9; ENST00000452259.5
External Link	RMBase: m6A_site_27732
mod ID: M6ASITE022802		Click to Show/Hide the Full List
mod site	chr1:44740945-44740946:+		[4]
Sequence	TGCCAATGTAAGGACTGTGAACTTGGAGAAATCCTGTGTTT
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000493027.5; ENST00000455186.5; ENST00000452259.5; ENST00000372224.9
External Link	RMBase: m6A_site_27733
mod ID: M6ASITE022803		Click to Show/Hide the Full List
mod site	chr1:44740992-44740993:+		[5]
Sequence	AATGGGCAGAAGGAGGTGCCACAAAGGGCAAAGAGGTAGGT
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000372224.9; ENST00000493027.5; ENST00000455186.5; ENST00000452259.5
External Link	RMBase: m6A_site_27734
mod ID: M6ASITE022804		Click to Show/Hide the Full List
mod site	chr1:44746482-44746483:+		[4]
Sequence	TTAGGTAGCAGCTGTCAGGAACTTGCCCCTGCCCATAAGAT
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000452259.5; ENST00000480574.1; ENST00000455186.5; ENST00000372224.9; ENST00000372217.5; ENST00000493027.5
External Link	RMBase: m6A_site_27735
mod ID: M6ASITE022805		Click to Show/Hide the Full List
mod site	chr1:44747411-44747412:+		[4]
Sequence	TGATGATGTGGCTGCAATAAACCCAGAACTCTTACAGCTTC
Motif Score	2.185083333
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000493027.5; ENST00000455186.5; ENST00000452259.5; ENST00000372217.5; ENST00000372224.9; ENST00000480574.1
External Link	RMBase: m6A_site_27736
mod ID: M6ASITE022806		Click to Show/Hide the Full List
mod site	chr1:44747418-44747419:+		[4]
Sequence	GTGGCTGCAATAAACCCAGAACTCTTACAGCTTCTTCCCTT
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000455186.5; ENST00000372224.9; ENST00000372217.5; ENST00000493027.5; ENST00000452259.5; ENST00000480574.1
External Link	RMBase: m6A_site_27737
mod ID: M6ASITE022807		Click to Show/Hide the Full List
mod site	chr1:44747450-44747451:+		[4]
Sequence	TCTTCCCTTACATCCGAAGGACAATCTGCCCTTGCAGGAAA
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000452259.5; ENST00000480574.1; ENST00000372217.5; ENST00000493027.5; ENST00000455186.5; ENST00000372224.9
External Link	RMBase: m6A_site_27738
mod ID: M6ASITE022808		Click to Show/Hide the Full List
mod site	chr1:44747653-44747654:+		[4]
Sequence	ATTTGATTTGTTTTTCAGAAACAAAAACGGAGATCCGTCAA
Motif Score	2.20572619
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000455186.5; ENST00000452259.5; ENST00000493027.5; ENST00000480574.1; ENST00000372224.9; ENST00000372217.5
External Link	RMBase: m6A_site_27739
mod ID: M6ASITE022809		Click to Show/Hide the Full List
mod site	chr1:44750348-44750349:+		[4]
Sequence	CCCCTTTCCTGGTAGCTGGGACCTATTTCACCTTGTACAGA
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000372217.5; ENST00000452259.5; ENST00000480574.1; ENST00000455186.5; ENST00000493027.5; ENST00000372224.9
External Link	RMBase: m6A_site_27740
mod ID: M6ASITE022810		Click to Show/Hide the Full List
mod site	chr1:44750370-44750371:+		[4]
Sequence	CTATTTCACCTTGTACAGAAACTTGGAGGTTTGCCCCTGAC
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000455186.5; ENST00000452259.5; ENST00000480574.1; ENST00000372224.9; ENST00000493027.5; ENST00000372217.5
External Link	RMBase: m6A_site_27741
mod ID: M6ASITE022811		Click to Show/Hide the Full List
mod site	chr1:44750507-44750508:+		[5]
Sequence	CATCACGGCTCAGGAGAATGACATGGAGGTGGAGCTGCCTG
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000452259.5; ENST00000372224.9; ENST00000493027.5; ENST00000480574.1; ENST00000372217.5; ENST00000455186.5
External Link	RMBase: m6A_site_27742
mod ID: M6ASITE022812		Click to Show/Hide the Full List
mod site	chr1:44750537-44750538:+		[4]
Sequence	GGAGCTGCCTGCAGCTGCAAACTCCCGCAAGCAGTTTTCAG
Motif Score	2.627720238
Cell/Tissue List	HeLa; BGC823; NB4; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9; ENST00000452259.5; ENST00000480574.1; ENST00000455186.5; ENST00000493027.5
External Link	RMBase: m6A_site_27743
mod ID: M6ASITE022813		Click to Show/Hide the Full List
mod site	chr1:44753239-44753240:+		[4]
Sequence	CCGAGGCAGCTCTTCTGCAAACCCTGTGAACTCAGGTAGAC
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; BGC823; NB4; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000455186.5; ENST00000372217.5; ENST00000452259.5; ENST00000372224.9; ENST00000493027.5
External Link	RMBase: m6A_site_27744
mod ID: M6ASITE022814		Click to Show/Hide the Full List
mod site	chr1:44753248-44753249:+		[4]
Sequence	CTCTTCTGCAAACCCTGTGAACTCAGGTAGACACACTGAGC
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; NB4; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000372217.5; ENST00000493027.5; ENST00000452259.5; ENST00000372224.9; ENST00000455186.5
External Link	RMBase: m6A_site_27745
mod ID: M6ASITE022815		Click to Show/Hide the Full List
mod site	chr1:44753777-44753778:+		[4]
Sequence	GGAAGTGGAAAAAATGAAGAACAAGCGAGAAGAGAAGAAGG
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; hESC-HEK293T; NB4; MM6
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000372224.9; ENST00000493027.5; ENST00000452259.5; ENST00000372217.5; ENST00000455186.5
External Link	RMBase: m6A_site_27746
mod ID: M6ASITE022816		Click to Show/Hide the Full List
mod site	chr1:44753804-44753805:+		[4]
Sequence	AGAAGAGAAGAAGGCCCAGAACTCTGAAATGAGAATGAAGA
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; hNPCs; NB4; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000455186.5; ENST00000372217.5; ENST00000493027.5; ENST00000452259.5; ENST00000372224.9
External Link	RMBase: m6A_site_27747
mod ID: M6ASITE022817		Click to Show/Hide the Full List
mod site	chr1:44754771-44754772:+		[4]
Sequence	GTATGACAGTAGTTTTCCAAACTGGGAATTTGCCCGAATGA
Motif Score	2.627720238
Cell/Tissue List	HeLa; hNPCs; NB4; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000372217.5; ENST00000455186.5; ENST00000452259.5; ENST00000372224.9; ENST00000493027.5
External Link	RMBase: m6A_site_27748
mod ID: M6ASITE022818		Click to Show/Hide the Full List
mod site	chr1:44756132-44756133:+		[5]
Sequence	AGCAAGTGTCTCCTCTTGGTACATGAACCCAAGTTGAAAGT
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000452259.5; ENST00000372224.9; ENST00000372217.5; ENST00000455186.5; ENST00000493027.5
External Link	RMBase: m6A_site_27749
mod ID: M6ASITE022819		Click to Show/Hide the Full List
mod site	chr1:44756138-44756139:+		[4]
Sequence	TGTCTCCTCTTGGTACATGAACCCAAGTTGAAAGTGGACTT
Motif Score	2.930744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000372224.9; ENST00000452259.5; ENST00000455186.5; ENST00000372217.5; ENST00000493027.5
External Link	RMBase: m6A_site_27750
mod ID: M6ASITE022820		Click to Show/Hide the Full List
mod site	chr1:44756155-44756156:+		[4]
Sequence	TGAACCCAAGTTGAAAGTGGACTTAACAAAGTATCTGGAGA
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000372217.5; ENST00000452259.5; ENST00000493027.5; ENST00000372224.9
External Link	RMBase: m6A_site_27751
mod ID: M6ASITE022821		Click to Show/Hide the Full List
mod site	chr1:44756160-44756161:+		[5]
Sequence	CCAAGTTGAAAGTGGACTTAACAAAGTATCTGGAGAACCAA
Motif Score	2.168095238
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000493027.5; ENST00000372224.9; ENST00000452259.5; ENST00000372217.5
External Link	RMBase: m6A_site_27752
mod ID: M6ASITE022822		Click to Show/Hide the Full List
mod site	chr1:44756176-44756177:+		[4]
Sequence	CTTAACAAAGTATCTGGAGAACCAAGCATTCTGCTTTGACT
Motif Score	2.930744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000452259.5; ENST00000493027.5; ENST00000372217.5; ENST00000372224.9
External Link	RMBase: m6A_site_27753
mod ID: M6ASITE022823		Click to Show/Hide the Full List
mod site	chr1:44756211-44756212:+		[4]
Sequence	TTGACTTTGCATTTGATGAAACAGCTTCGAATGAAGTTGTC
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000372224.9; ENST00000372217.5; ENST00000452259.5; ENST00000493027.5
External Link	RMBase: m6A_site_27754
mod ID: M6ASITE022824		Click to Show/Hide the Full List
mod site	chr1:44757580-44757581:+		[4]
Sequence	CAGCAAGGCCACTGGTACAGACAATCTTTGAAGGTGGAAAA
Motif Score	2.897386905
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000493027.5; ENST00000372217.5; ENST00000452259.5; ENST00000372224.9
External Link	RMBase: m6A_site_27755
mod ID: M6ASITE022825		Click to Show/Hide the Full List
mod site	chr1:44757625-44757626:+		[4]
Sequence	CTTGTTTTGCATATGGCCAGACAGGAAGTGGCAAGACACAT
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000372224.9; ENST00000372217.5; ENST00000452259.5; ENST00000493027.5
External Link	RMBase: m6A_site_27756
mod ID: M6ASITE022826		Click to Show/Hide the Full List
mod site	chr1:44757640-44757641:+		[4]
Sequence	GCCAGACAGGAAGTGGCAAGACACATGTGAGTATTGAGGCC
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000372217.5; ENST00000452259.5; ENST00000372224.9; ENST00000493027.5
External Link	RMBase: m6A_site_27757
mod ID: M6ASITE022827		Click to Show/Hide the Full List
mod site	chr1:44757920-44757921:+		[4]
Sequence	TTTGCAGACTATGGGCGGAGACCTCTCTGGGAAAGCCCAGA
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9; ENST00000452259.5; ENST00000493027.5
External Link	RMBase: m6A_site_27758
mod ID: M6ASITE022828		Click to Show/Hide the Full List
mod site	chr1:44758113-44758114:+		[5]
Sequence	TGGGCCTGGAAGTCTATGTGACATTCTTCGAGATCTACAAT
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000372224.9; ENST00000372217.5
External Link	RMBase: m6A_site_27759
mod ID: M6ASITE022829		Click to Show/Hide the Full List
mod site	chr1:44759221-44759222:+		[5]
Sequence	ACAGCTGTTTGACCTGCTCAACAAGAAGGCCAAGCTGCGCG
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9
External Link	RMBase: m6A_site_27760
mod ID: M6ASITE022830		Click to Show/Hide the Full List
mod site	chr1:44759329-44759330:+		[5]
Sequence	TGATGTCATCAAGATGATCGACATGGGCAGCGCCTGCAGGT
Motif Score	2.865571429
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9
External Link	RMBase: m6A_site_27761
mod ID: M6ASITE022831		Click to Show/Hide the Full List
mod site	chr1:44760292-44760293:+		[4]
Sequence	ACCACAGAACCTCTGGGCAGACATTTGCCAACTCCAATTCC
Motif Score	2.897386905
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000372224.9; ENST00000372217.5
External Link	RMBase: m6A_site_27762
mod ID: M6ASITE022832		Click to Show/Hide the Full List
mod site	chr1:44760413-44760414:+		[4]
Sequence	AGGGAATGAGCGAGGCGCGGACACTTCCAGTGCTGACCGGC
Motif Score	3.643047619
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000372224.9; ENST00000372217.5
External Link	RMBase: m6A_site_27763
mod ID: M6ASITE022833		Click to Show/Hide the Full List
mod site	chr1:44760436-44760437:+		[4]
Sequence	CTTCCAGTGCTGACCGGCAGACCCGCATGGAGGGCGCAGAA
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9
External Link	RMBase: m6A_site_27764
mod ID: M6ASITE022834		Click to Show/Hide the Full List
mod site	chr1:44760461-44760462:+		[5]
Sequence	CATGGAGGGCGCAGAAATCAACAAGAGTCTCTTAGCCCTGA
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9
External Link	RMBase: m6A_site_27765
mod ID: M6ASITE022835		Click to Show/Hide the Full List
mod site	chr1:44760611-44760612:+		[4]
Sequence	GAGTGCATCAGGGCCCTGGGACAGAACAAGGCTCACACCCC
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000423289.1; ENST00000372224.9; ENST00000372217.5
External Link	RMBase: m6A_site_27766
mod ID: M6ASITE022836		Click to Show/Hide the Full List
mod site	chr1:44760616-44760617:+		[4]
Sequence	CATCAGGGCCCTGGGACAGAACAAGGCTCACACCCCGTTCC
Motif Score	2.951386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000372224.9; ENST00000372217.5; ENST00000423289.1
External Link	RMBase: m6A_site_27767
mod ID: M6ASITE022837		Click to Show/Hide the Full List
mod site	chr1:44760651-44760652:+		[5]
Sequence	CGTTCCGTGAGAGCAAGCTGACACAGGTGCTGAGGGACTCC
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000372224.9; ENST00000423289.1; ENST00000372217.5
External Link	RMBase: m6A_site_27768
mod ID: M6ASITE022838		Click to Show/Hide the Full List
mod site	chr1:44760667-44760668:+		[4]
Sequence	GCTGACACAGGTGCTGAGGGACTCCTTCATTGGGGAGAACT
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000372217.5; ENST00000423289.1; ENST00000372224.9
External Link	RMBase: m6A_site_27769
mod ID: M6ASITE022839		Click to Show/Hide the Full List
mod site	chr1:44760685-44760686:+		[4]
Sequence	GGACTCCTTCATTGGGGAGAACTCTAGGACTTGCATGGTGA
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9; ENST00000423289.1
External Link	RMBase: m6A_site_27770
mod ID: M6ASITE022840		Click to Show/Hide the Full List
mod site	chr1:44760693-44760694:+		[4]
Sequence	TCATTGGGGAGAACTCTAGGACTTGCATGGTGAGTAGGGTC
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000423289.1; ENST00000372224.9; ENST00000372217.5
External Link	RMBase: m6A_site_27771
mod ID: M6ASITE022841		Click to Show/Hide the Full List
mod site	chr1:44761961-44761962:+		[5]
Sequence	CTCCTGTGAATATACTTTAAACACCCTGAGATATGCAGACA
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000423289.1; ENST00000372217.5; ENST00000372224.9
External Link	RMBase: m6A_site_27776
mod ID: M6ASITE022842		Click to Show/Hide the Full List
mod site	chr1:44762403-44762404:+		[4]
Sequence	AGCAGTTGATTCAAATGGAAACAGAAGAGATGGAAGCCTGC
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000372217.5; ENST00000472235.1; ENST00000423289.1; ENST00000372224.9
External Link	RMBase: m6A_site_27779
mod ID: M6ASITE022843		Click to Show/Hide the Full List
mod site	chr1:44762564-44762565:+		[4]
Sequence	TTATCCAAGGAAGAGGAGGAACTGTCTTCCCAGATGTCCAG
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000372224.9; ENST00000372217.5; ENST00000472235.1; ENST00000423289.1
External Link	RMBase: m6A_site_27780
mod ID: M6ASITE022852		Click to Show/Hide the Full List
mod site	chr1:44766830-44766831:+		[4]
Sequence	CTCCCTGTGTTGTAGCAAGGACCAGACTGGCTTGAGCTCTC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9; ENST00000472235.1
External Link	RMBase: m6A_site_27781
mod ID: M6ASITE022863		Click to Show/Hide the Full List
mod site	chr1:44766835-44766836:+		[4]
Sequence	TGTGTTGTAGCAAGGACCAGACTGGCTTGAGCTCTCTGAGA
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000472235.1; ENST00000372224.9; ENST00000372217.5
External Link	RMBase: m6A_site_27782
mod ID: M6ASITE022874		Click to Show/Hide the Full List
mod site	chr1:44766871-44766872:+		[4]
Sequence	TGAGATGACCGAGCAGCCAGACTATGACCTGGAGACCTTTG
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000372217.5; ENST00000472235.1; ENST00000372224.9
External Link	RMBase: m6A_site_27783
mod ID: M6ASITE022885		Click to Show/Hide the Full List
mod site	chr1:44766885-44766886:+		[4]
Sequence	AGCCAGACTATGACCTGGAGACCTTTGTGAACAAAGCGGAA
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9
External Link	RMBase: m6A_site_27784
mod ID: M6ASITE022896		Click to Show/Hide the Full List
mod site	chr1:44766895-44766896:+		[4]
Sequence	TGACCTGGAGACCTTTGTGAACAAAGCGGAATCTGCTCTGG
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; hESC-HEK293T; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9
External Link	RMBase: m6A_site_27785
mod ID: M6ASITE022907		Click to Show/Hide the Full List
mod site	chr1:44767148-44767149:+		[4]
Sequence	CTGGAAGAGCAGGCTAGCAGACAAATAAGCAGCAAGAAACG
Motif Score	2.897386905
Cell/Tissue List	HeLa; hESC-HEK293T; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; HEC-1-A; NB4
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000372224.9; ENST00000372217.5
External Link	RMBase: m6A_site_27786
mod ID: M6ASITE022918		Click to Show/Hide the Full List
mod site	chr1:44767208-44767209:+		[5]
Sequence	ATAAAAATCTGTTTGGTTTGACACCCAGCCTCTTCCCTGGC
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9
External Link	RMBase: m6A_site_27787
mod ID: M6ASITE022929		Click to Show/Hide the Full List
mod site	chr1:44767241-44767242:+		[4]
Sequence	TCCCTGGCCCTCCCCAGAGAACTTTGGGTACCTGGTGGGTC
Motif Score	3.373380952
Cell/Tissue List	HeLa; A549; LCLs; H1299; MM6; Jurkat
Seq Type List	m6A-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9
External Link	RMBase: m6A_site_27788
mod ID: M6ASITE022940		Click to Show/Hide the Full List
mod site	chr1:44767282-44767283:+		[4]
Sequence	TAGGCAGGGTCTGAGCTGGGACAGGTTCTGGTAAATGCCAA
Motif Score	3.643047619
Cell/Tissue List	HeLa; HEK293; A549; LCLs; H1299; MM6; Jurkat; TREX
Seq Type List	m6A-seq; m6A-REF-seq; MeRIP-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9
External Link	RMBase: m6A_site_27789
mod ID: M6ASITE022951		Click to Show/Hide the Full List
mod site	chr1:44767357-44767358:+		[4]
Sequence	GGGGGTCAGAGTGACATGGGACACTCCTTTTCTGTTCCTCA
Motif Score	3.643047619
Cell/Tissue List	HeLa; LCLs; H1299; MM6; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000372224.9; ENST00000372217.5
External Link	RMBase: m6A_site_27790
mod ID: M6ASITE022962		Click to Show/Hide the Full List
mod site	chr1:44767493-44767494:+		[6]
Sequence	GCAGCATCCTGCCTGCGTGGACTGGCTGCTAATGGAGAGCT
Motif Score	4.065041667
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9
External Link	RMBase: m6A_site_27791
mod ID: M6ASITE022973		Click to Show/Hide the Full List
mod site	chr1:44767580-44767581:+		[6]
Sequence	CAGCTATCTGCTGGCTCTAAACCTTCTACGCCTTTGGGCCG
Motif Score	2.185083333
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000372224.9; ENST00000372217.5
External Link	RMBase: m6A_site_27792
mod ID: M6ASITE022984		Click to Show/Hide the Full List
mod site	chr1:44767640-44767641:+		[6]
Sequence	TTTAAAAAAATGTTTCTGAGACCTCTTTCTACTTTACTGTC
Motif Score	2.876744048
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000372217.5; ENST00000372224.9
External Link	RMBase: m6A_site_27793
mod ID: M6ASITE022991		Click to Show/Hide the Full List
mod site	chr1:44767711-44767712:+		[5]
Sequence	TTTCTGTTTTATGTGTTTATACATTGTATGTAACAATAAAG
Motif Score	2.110482143
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000372224.9; ENST00000372217.5
External Link	RMBase: m6A_site_27794

Ref 1	NAT10-mediated N4-acetylcytidine mRNA modification regulates self-renewal in human embryonic stem cells. Nucleic Acids Res. 2023 Sep 8;51(16):8514-8531. doi: 10.1093/nar/gkad628.
Ref 2	Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome. Nat Biotechnol. 2012 Feb 12;30(3):253-60. doi: 10.1038/nbt.2122.
Ref 3	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 4	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 5	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 6	Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018 Jan;3(1):108-120. doi: 10.1038/s41564-017-0056-8. Epub 2017 Nov 6.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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