m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00024)
Target Name hsa-miR-19a-3p
Gene Name hsa-miR-19a-3p
miRBase ID
MIMAT0000073
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
hsa-miR-19a-3p can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
Browse Regulator
Browse Disease
Methyltransferase-like 14 (METTL14) [WRITER]
 Regulator Info 
In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene [1]
Response Summary METTL14 increased the m6A modification of pri-miR-19a and promoted the processing of mature hsa-miR-19a-3p, thus promoting the proliferation and invasion of atherosclerotic vascular endothelial cells.
Target Regulation Up regulation
Responsed Disease Atherosclerosis ICD-11: BD40.Z
 Disease Info 
Cell Process Cell migration and invasion
Epithelial-mesenchymal transition
In-vitro Model ASVEC cell line (Atherosclerotic vascular endothelial cells)
Atherosclerosis [ICD-11: BD40]
 Disease Info 
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response [1]
Response Summary METTL14 increased the m6A modification of pri-miR-19a and promoted the processing of mature hsa-miR-19a-3p, thus promoting the proliferation and invasion of atherosclerotic vascular endothelial cells.
Responsed Disease Atherosclerosis [ICD-11: BD40.Z]
Target Regulator Methyltransferase-like 14 (METTL14) WRITER
 Regulator Info 
Target Regulation Up regulation
Cell Process Cell migration and invasion
Epithelial-mesenchymal transition
In-vitro Model ASVEC cell line (Atherosclerotic vascular endothelial cells)
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator
Non-coding RNA
m6A Regulator: Methyltransferase-like 14 (METTL14)
 Regulator Info 
In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05435
 Crosstalk Info 
Epigenetic Regulator hsa-miR-19a-3p
Crosstalk relationship m6A → ncRNA
Disease Atherosclerosis
 Disease Info 
References
Ref 1 METTL14 regulates M6A methylation-modified primary miR-19a to promote cardiovascular endothelial cell proliferation and invasion. Eur Rev Med Pharmacol Sci. 2020 Jun;24(12):7015-7023. doi: 10.26355/eurrev_202006_21694.