RNA-seq Results

Results indicating the target gene (CDKN1A ) expression regulated by m6A regulator (METTL3 )
2B90: Colon cancer
In total 1 results
Result 1 indicating the CDKN1A expression regulated by METTL3
Cell Line CT26 cell line CVCL_7254
Condition Colon adenocarcinoma Mus musculus
Treatment: METTL3 knockout CT26 cells
Control: CT26 cells
 GSE142589
Regulation
logFC: -9.60E-01
 p-value: 6.59E-03
2C60: Breast cancer
In total 1 results
Result 1 indicating the CDKN1A expression regulated by METTL3
Cell Line MDA-MB-231 CVCL_0062
Condition Breast cancer Homo sapiens
Treatment: METTL3 knockdown MDA-MB-231 cells
Control: MDA-MB-231 cells
 GSE70061
Regulation
logFC: 2.73E+00
 p-value: 3.74E-02
Healthy
In total 11 results
Result 1 indicating the CDKN1A expression regulated by METTL3
Cell Line Cerebral cortex
Condition Healthy Mus musculus
Treatment: FTO (f/f, Emx1-cre) cerebral cortex
Control: Wild type cerebral cortex
 GSE154992
Regulation
logFC: 1.04E+00
 p-value: 5.18E-13
Result 2 indicating the CDKN1A expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3-deficient liver
Control: Wild type liver cells
 GSE197800
Regulation
logFC: 1.69E+00
 p-value: 3.13E-07
Result 3 indicating the CDKN1A expression regulated by METTL3
Cell Line Neurite
Condition Healthy Mus musculus
Treatment: Mettl3-/- neurite
Control: Wild type neurite
 GSE171199
Regulation
logFC: 7.16E-01
 p-value: 3.38E-03
Result 4 indicating the CDKN1A expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3 knockout liver
Control: Wild type liver cells
 GSE198512
Regulation
logFC: 4.22E+00
 p-value: 7.77E-03
Result 5 indicating the CDKN1A expression regulated by METTL3
Cell Line LX2 cell line CVCL_5792
Condition Healthy Homo sapiens
Treatment: shMETTL3 LX2 cells
Control: shLuc LX2 cells
 GSE207909
Regulation
logFC: 7.88E-01
 p-value: 3.07E-21
Result 6 indicating the CDKN1A expression regulated by METTL3
Cell Line mouse embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3-/- ESCs
Control: Wild type ESCs
 GSE145309
Regulation
logFC: 7.56E-01
 p-value: 2.65E-70
Result 7 indicating the CDKN1A expression regulated by METTL3
Cell Line Tfh cell line
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Tfh cells
Control: Wild type splenic Tfh cells
 GSE129648
Regulation
logFC: 2.20E+00
 p-value: 5.58E-07
Result 8 indicating the CDKN1A expression regulated by METTL3
Cell Line Th1 cell line CVCL_5J51
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Th1 cells
Control: Wild type splenic Th1 cells
 GSE129648
Regulation
logFC: 1.49E+00
 p-value: 9.91E-06
Result 9 indicating the CDKN1A expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3 knockout mESCs
Control: Wild type mESCs
 GSE156481
Regulation
logFC: -6.91E-01
 p-value: 7.78E-05
Result 10 indicating the CDKN1A expression regulated by METTL3
Cell Line E14.5 LSK cell line
Condition Healthy Mus musculus
Treatment: METTL3 knockout E14.5 LSK cells
Control: Wild type E14.5 LSK cells
 GSE148882
Regulation
logFC: 6.67E-01
 p-value: 4.95E-04
Result 11 indicating the CDKN1A expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3 knockout ES cells
Control: Wild type ES cells
 GSE157262
Regulation
logFC: -6.09E-01
 p-value: 9.93E-03