Epigenetic Target Information

General Information of the Epigenetic Target (ID: EPITAR00562)
Target Name NAD-dependent protein deacetylase sirtuin-3, mitochondrial (SIRT3)
Synonyms
SIR2L3: hSIRT3; NAD-dependent protein delactylase sirtuin-3; Regulatory protein SIR2 homolog 3; SIR2-like protein 3
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Gene Name SIRT3
Sequence
MAFWGWRAAAALRLWGRVVERVEAGGGVGPFQACGCRLVLGGRDDVSAGLRGSHGARGEPLDPARPLQRPPRPEVPRAFRRQPRAAAPSFFFSSIKGGRRSISFSVGASSVVGSGGSSDKGKLSLQDVAELIRARACQRVVVMVGAGISTPSGIPDFRSPGSGLYSNLQQYDLPYPEAIFELPFFFHNPKPFFTLAKELYPGNYKPNVTHYFLRLLHDKGLLLRLYTQNIDGLERVSGIPASKLVEAHGTFASATCTVCQRPFPGEDIRADVMADRVPRCPVCTGVVKPDIVFFGEPLPQRFLLHVVDFPMADLLLILGTSLEVEPFASLTEAVRSSVPRLLINRDLVGPLAWHPRSRDVAQLGDVVHGVESLVELLGWTEEMRDLVQRETGKLDGPDK
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Family Sirtuin family, Class I subfamily
Function
NAD-dependent protein deacetylase (PubMed:12186850, PubMed:12374852, PubMed:16788062, PubMed:18680753, PubMed:18794531, PubMed:19535340, PubMed:23283301, PubMed:24121500, PubMed:24252090). Activates or deactivates mitochondrial target proteins by deacetylating key lysine residues (PubMed:12186850, PubMed:12374852, PubMed:16788062, PubMed:18680753, PubMed:18794531, PubMed:23283301, PubMed:24121500, PubMed:24252090, PubMed:38146092). Known targets include ACSS1, IDH, GDH, SOD2, PDHA1, LCAD, SDHA, MRPL12 and the ATP synthase subunit ATP5PO (PubMed:16788062, PubMed:18680753, PubMed:19535340, PubMed:24121500, PubMed:24252090, PubMed:38146092). Contributes to the regulation of the cellular energy metabolism (PubMed:24252090). Important for regulating tissue-specific ATP levels (PubMed:18794531). In response to metabolic stress, deacetylates transcription factor FOXO3 and recruits FOXO3 and mitochondrial RNA polymerase POLRMT to mtDNA to promote mtDNA transcription (PubMed:23283301). Acts as a regulator of ceramide metabolism by mediating deacetylation of ceramide synthases CERS1, CERS2 and CERS6, thereby increasing their activity and promoting mitochondrial ceramide accumulation (By similarity). Regulates hepatic lipogenesis (By similarity). Uses NAD(+) substrate imported by SLC25A47, triggering downstream activation of PRKAA1/AMPK-alpha signaling cascade that ultimately downregulates sterol regulatory element-binding protein (SREBP) transcriptional activities and ATP-consuming lipogenesis to restore cellular energy balance (By similarity). In addition to protein deacetylase activity, also acts as a protein-lysine deacylase by mediating delactylation of proteins, such as CCNE2 and 'Lys-16' of histone H4 (H4K16la) (PubMed:36896611, PubMed:37720100). {ECO:0000250|UniProtKB:Q8R104, ECO:0000269|PubMed:12186850, ECO:0000269|PubMed:12374852, ECO:0000269|PubMed:16788062, ECO:0000269|PubMed:18680753, ECO:0000269|PubMed:18794531, ECO:0000269|PubMed:19535340, ECO:0000269|PubMed:23283301, ECO:0000269|PubMed:24121500, ECO:0000269|PubMed:24252090, ECO:0000269|PubMed:36896611, ECO:0000269|PubMed:37720100, ECO:0000269|PubMed:38146092}.
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Gene ID 23410
HGNC ID HGNC:14931
Ensembl Gene ID ENSG00000142082
KEGG ID hsa:23410
Chromosomal Location 11p15.5
RNA Modification Sequencing Data Associated with the Target (ID: EPITAR00562)
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (SIRT3)
Adenosine-to-Inosine editing (A-to-I)
In total 2 m6A sequence/site(s) in this target gene
mod ID: A2ISITE004507 Click to Show/Hide the Full List
mod site chr11:221229-221230:- [1]
Sequence GCTATTTGAGAGGCTGAGGAAGGAGGATTGCTTGAGCCCAG
Transcript ID List ENST00000529382.5; ENST00000532837.5; ENST00000524564.5; ENST00000382743.9; rmsk_3457007; ENST00000525319.5; ENST00000529937.1; ENST00000532956.5
External Link RMBase: RNA-editing_site_19522
mod ID: A2ISITE004508 Click to Show/Hide the Full List
mod site chr11:221341-221342:- [1]
Sequence AAGGCAGGAAGATTGCCTGAAGCTAGGCATTTGAGACCAGC
Transcript ID List ENST00000532837.5; ENST00000529937.1; ENST00000532956.5; ENST00000529382.5; ENST00000525319.5; rmsk_3457007; ENST00000382743.9; ENST00000524564.5
External Link RMBase: RNA-editing_site_19523
5-methylcytidine (m5C)
In total 2 m6A sequence/site(s) in this target gene
mod ID: M5CSITE004815 Click to Show/Hide the Full List
mod site chr11:216448-216449:-
Sequence TGCCTGTTTGCTGTGTTGAACTCTTCACTCTGCTGAAGCTC
Cell/Tissue List T24
Seq Type List Bisulfite-seq
Transcript ID List ENST00000524564.5; ENST00000525319.5; ENST00000529937.1; ENST00000382743.9; ENST00000532837.5
External Link RMBase: m5C_site_6199
mod ID: M5CSITE004816 Click to Show/Hide the Full List
mod site chr11:218823-218824:-
Sequence GGAAACTGGGAAGGTACAGACTGCTGAGGAGGACCATCCAA
Cell/Tissue List T24
Seq Type List Bisulfite-seq
Transcript ID List ENST00000529382.5; ENST00000382743.9; ENST00000532956.5; ENST00000529937.1; ENST00000525319.5; ENST00000524564.5; ENST00000532837.5
External Link RMBase: m5C_site_6200
N6-methyladenosine (m6A)
In total 57 m6A sequence/site(s) in this target gene
mod ID: M6ASITE002894 Click to Show/Hide the Full List
mod site chr11:215100-215101:- [2]
Sequence CACATACATTTTTGTCCAAAACTCTTCTTTATTTCAAGATG
Motif Score 2.627720238
Cell/Tissue List Huh7
Seq Type List MeRIP-seq
Transcript ID List ENST00000382743.9
External Link RMBase: m6A_site_124986
mod ID: M6ASITE002895 Click to Show/Hide the Full List
mod site chr11:215467-215468:- [3]
Sequence GGAATTGGTGACCTAGGAAAACTGTTGAATTCTAAAAAGAA
Motif Score 2.627720238
Cell/Tissue List HeLa; HEK293T; Huh7; iSLK
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000382743.9
External Link RMBase: m6A_site_124988
mod ID: M6ASITE002896 Click to Show/Hide the Full List
mod site chr11:215496-215497:- [3]
Sequence GACTTTGCGCCTTAATAAGAACAAAAGGTGGAATTGGTGAC
Motif Score 2.951386905
Cell/Tissue List HeLa; HEK293T; Huh7; iSLK
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000382743.9
External Link RMBase: m6A_site_124989
mod ID: M6ASITE002897 Click to Show/Hide the Full List
mod site chr11:215544-215545:- [4]
Sequence TGACGGCAATAGATTTAATGACAGTGACTCCCAGGAAGGGG
Motif Score 2.859755952
Cell/Tissue List kidney
Seq Type List m6A-REF-seq
Transcript ID List ENST00000382743.9
External Link RMBase: m6A_site_124990
mod ID: M6ASITE002898 Click to Show/Hide the Full List
mod site chr11:215587-215588:- [3]
Sequence AAAGCACTTCCCATTCTTGAACCTTGCCTACCCTGGGCTGA
Motif Score 2.930744048
Cell/Tissue List HeLa; HEK293T; GM12878; iSLK; MSC; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000382743.9
External Link RMBase: m6A_site_124991
mod ID: M6ASITE002899 Click to Show/Hide the Full List
mod site chr11:215610-215611:- [3]
Sequence TTACCTGCGTGTTTCCCCAGACAAAAGCACTTCCCATTCTT
Motif Score 2.897386905
Cell/Tissue List HeLa; HEK293T; GM12878; MT4; Huh7; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000382743.9
External Link RMBase: m6A_site_124992
mod ID: M6ASITE002900 Click to Show/Hide the Full List
mod site chr11:215762-215763:- [3]
Sequence TAGGAGGTGGAATCCACTGAACTGCTACTTCTGCACAGGCT
Motif Score 3.373380952
Cell/Tissue List HeLa; HEK293T; A549; HepG2; U2OS; H1B; GM12878; Huh7; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000382743.9
External Link RMBase: m6A_site_124993
mod ID: M6ASITE002901 Click to Show/Hide the Full List
mod site chr11:215785-215786:- [4]
Sequence TGGCCACCTGCTGGATTGTGACATAGGAGGTGGAATCCACT
Motif Score 2.859755952
Cell/Tissue List brain
Seq Type List m6A-REF-seq
Transcript ID List ENST00000382743.9
External Link RMBase: m6A_site_124994
mod ID: M6ASITE002902 Click to Show/Hide the Full List
mod site chr11:215820-215821:- [3]
Sequence GAAGGCATTACTCACTTAAAACCCAGGCTGAGTCCTGGCCA
Motif Score 2.185083333
Cell/Tissue List HeLa; HEK293T; A549; HepG2; U2OS; H1B; hESCs; fibroblasts; GM12878; Huh7; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000382743.9
External Link RMBase: m6A_site_124995
mod ID: M6ASITE002903 Click to Show/Hide the Full List
mod site chr11:215845-215846:- [3]
Sequence TGTTAGAGCTAATCTCTGAGACAGGGAAGGCATTACTCACT
Motif Score 2.897386905
Cell/Tissue List HeLa; HEK293T; brain; kidney; A549; HepG2; U2OS; hESCs; fibroblasts; GM12878; Huh7; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq; m6A-REF-seq
Transcript ID List ENST00000382743.9
External Link RMBase: m6A_site_124996
mod ID: M6ASITE002904 Click to Show/Hide the Full List
mod site chr11:215945-215946:- [3]
Sequence AGAAACAGATCTGTTCCAGAACATTCCAGCACTTTCTATCT
Motif Score 2.951386905
Cell/Tissue List HeLa; HEK293T; A549; HepG2; U2OS; hESCs; fibroblasts; GM12878; Huh7; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000382743.9
External Link RMBase: m6A_site_124997
mod ID: M6ASITE002905 Click to Show/Hide the Full List
mod site chr11:215961-215962:- [3]
Sequence ACTCAGCCTCTCCTCCAGAAACAGATCTGTTCCAGAACATT
Motif Score 2.20572619
Cell/Tissue List HeLa; HEK293T; A549; HepG2; U2OS; H1B; hESCs; GM12878; Huh7; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000382743.9
External Link RMBase: m6A_site_124998
mod ID: M6ASITE002906 Click to Show/Hide the Full List
mod site chr11:216063-216064:- [3]
Sequence TCTATTGGAACAGTCTGAGGACTGAAGGCATTTGTCCCTGG
Motif Score 4.065041667
Cell/Tissue List HeLa; HEK293T; A549; HepG2; U2OS; H1B; GM12878; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000382743.9
External Link RMBase: m6A_site_124999
mod ID: M6ASITE002907 Click to Show/Hide the Full List
mod site chr11:216074-216075:- [3]
Sequence GTGGCGTCCCCTCTATTGGAACAGTCTGAGGACTGAAGGCA
Motif Score 2.951386905
Cell/Tissue List HeLa; HEK293T; A549; HepG2; U2OS; H1B; HEK293A-TOA; iSLK; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000382743.9
External Link RMBase: m6A_site_125000
mod ID: M6ASITE002908 Click to Show/Hide the Full List
mod site chr11:216106-216107:- [3]
Sequence TGACATGAGTTGGAAAGGGAACCCTGGGATACGTGGCGTCC
Motif Score 2.930744048
Cell/Tissue List HeLa; HEK293T; A549; HepG2; U2OS; Huh7; HEK293A-TOA; iSLK; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000382743.9
External Link RMBase: m6A_site_125001
mod ID: M6ASITE002909 Click to Show/Hide the Full List
mod site chr11:216137-216138:- [3]
Sequence CATTTAGTCTCCTCAAAGGGACTGCAGGTGTTGACATGAGT
Motif Score 4.065041667
Cell/Tissue List HeLa; HEK293T; A549; HepG2; Huh7; HEK293A-TOA; iSLK; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000382743.9
External Link RMBase: m6A_site_125002
mod ID: M6ASITE002910 Click to Show/Hide the Full List
mod site chr11:216158-216159:- [5]
Sequence TGTTCTTTCCAGCATGAAATACATTTAGTCTCCTCAAAGGG
Motif Score 2.110482143
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000382743.9; ENST00000529937.1
External Link RMBase: m6A_site_125003
mod ID: M6ASITE002911 Click to Show/Hide the Full List
mod site chr11:216297-216298:- [3]
Sequence CTGTTGGTTACAAGATCCAGACTTGGGCCGAGCGGTCCCCA
Motif Score 3.319380952
Cell/Tissue List HeLa; HepG2; HEK293T; A549; H1A; H1B; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MeRIP-seq; DART-seq
Transcript ID List ENST00000525319.5; ENST00000382743.9; ENST00000532837.5; ENST00000529937.1
External Link RMBase: m6A_site_125004
mod ID: M6ASITE002912 Click to Show/Hide the Full List
mod site chr11:216308-216309:- [6]
Sequence AAGCTCGGCATCTGTTGGTTACAAGATCCAGACTTGGGCCG
Motif Score 2.07285119
Cell/Tissue List HEK293T; hESC-HEK293T
Seq Type List DART-seq; MAZTER-seq
Transcript ID List ENST00000529937.1; ENST00000382743.9; ENST00000532837.5; ENST00000525319.5
External Link RMBase: m6A_site_125005
mod ID: M6ASITE002913 Click to Show/Hide the Full List
mod site chr11:216361-216362:- [3]
Sequence CAGACCAACTGGAATCCCAGACCGAGTCTGCTTTCTGTGCC
Motif Score 2.876744048
Cell/Tissue List HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000529937.1; ENST00000382743.9; ENST00000525319.5; ENST00000532837.5
External Link RMBase: m6A_site_125006
mod ID: M6ASITE002914 Click to Show/Hide the Full List
mod site chr11:216378-216379:- [3]
Sequence ACCCTCTTGAACTGAATCAGACCAACTGGAATCCCAGACCG
Motif Score 2.876744048
Cell/Tissue List HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000525319.5; ENST00000529937.1; ENST00000382743.9; ENST00000532837.5
External Link RMBase: m6A_site_125007
mod ID: M6ASITE002915 Click to Show/Hide the Full List
mod site chr11:216388-216389:- [3]
Sequence TCTGACTGTGACCCTCTTGAACTGAATCAGACCAACTGGAA
Motif Score 3.373380952
Cell/Tissue List HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; CD8T; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List ENST00000532837.5; ENST00000525319.5; ENST00000529937.1; ENST00000382743.9
External Link RMBase: m6A_site_125008
mod ID: M6ASITE002916 Click to Show/Hide the Full List
mod site chr11:216404-216405:- [7]
Sequence ATGGAAAAAGCTTTCTTCTGACTGTGACCCTCTTGAACTGA
Motif Score 3.28175
Cell/Tissue List A549
Seq Type List m6A-CLIP/IP
Transcript ID List ENST00000382743.9; ENST00000529937.1; ENST00000532837.5; ENST00000525319.5; ENST00000524564.5
External Link RMBase: m6A_site_125009
mod ID: M6ASITE002917 Click to Show/Hide the Full List
mod site chr11:216442-216443:- [6]
Sequence TTTGCTGTGTTGAACTCTTCACTCTGCTGAAGCTCCTAATG
Motif Score 2.469291667
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000525319.5; ENST00000532837.5; ENST00000524564.5; ENST00000382743.9; ENST00000529937.1
External Link RMBase: m6A_site_125010
mod ID: M6ASITE002918 Click to Show/Hide the Full List
mod site chr11:216449-216450:- [3]
Sequence CTGCCTGTTTGCTGTGTTGAACTCTTCACTCTGCTGAAGCT
Motif Score 3.373380952
Cell/Tissue List HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000382743.9; ENST00000525319.5; ENST00000524564.5; ENST00000532837.5; ENST00000529937.1
External Link RMBase: m6A_site_125011
mod ID: M6ASITE002919 Click to Show/Hide the Full List
mod site chr11:216482-216483:- [5]
Sequence AGGGCCACCCCGTCACATATACAAAGGAGCTGCCTGCCTGT
Motif Score 2.110482143
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000525319.5; ENST00000529937.1; ENST00000382743.9; ENST00000532837.5; ENST00000524564.5
External Link RMBase: m6A_site_125012
mod ID: M6ASITE002920 Click to Show/Hide the Full List
mod site chr11:216575-216576:- [3]
Sequence AGAATATGTGAACTGAGTGGACACCCGAGGCTGCCACTGGA
Motif Score 3.643047619
Cell/Tissue List HeLa; HepG2; HEK293T; A549; hESC-HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MeRIP-seq; DART-seq; MAZTER-seq
Transcript ID List ENST00000524564.5; ENST00000525319.5; ENST00000532956.5; ENST00000529937.1; ENST00000532837.5; ENST00000382743.9
External Link RMBase: m6A_site_125013
mod ID: M6ASITE002921 Click to Show/Hide the Full List
mod site chr11:216584-216585:- [3]
Sequence GGTGAAACCAGAATATGTGAACTGAGTGGACACCCGAGGCT
Motif Score 3.373380952
Cell/Tissue List HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000532956.5; ENST00000525319.5; ENST00000529937.1; ENST00000524564.5; ENST00000532837.5; ENST00000382743.9
External Link RMBase: m6A_site_125014
mod ID: M6ASITE002922 Click to Show/Hide the Full List
mod site chr11:216598-216599:- [3]
Sequence AGACAGCTTGGGCAGGTGAAACCAGAATATGTGAACTGAGT
Motif Score 2.185083333
Cell/Tissue List HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List ENST00000525319.5; ENST00000529937.1; ENST00000532956.5; ENST00000382743.9; ENST00000532837.5; ENST00000524564.5
External Link RMBase: m6A_site_125015
mod ID: M6ASITE002923 Click to Show/Hide the Full List
mod site chr11:216616-216617:- [3]
Sequence ACAAGACCTCATGCCTGAAGACAGCTTGGGCAGGTGAAACC
Motif Score 2.897386905
Cell/Tissue List HeLa; HepG2; HEK293T; A549; hESC-HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List m6A-seq; MeRIP-seq; MAZTER-seq; m6A-CLIP/IP
Transcript ID List ENST00000525319.5; ENST00000532837.5; ENST00000529937.1; ENST00000382743.9; ENST00000532956.5; ENST00000529382.5; ENST00000524564.5
External Link RMBase: m6A_site_125016
mod ID: M6ASITE002924 Click to Show/Hide the Full List
mod site chr11:216631-216632:- [3]
Sequence CACATCCCAATTCTGACAAGACCTCATGCCTGAAGACAGCT
Motif Score 2.876744048
Cell/Tissue List HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000524564.5; ENST00000532837.5; ENST00000529937.1; ENST00000529382.5; ENST00000532956.5; ENST00000525319.5; ENST00000382743.9
External Link RMBase: m6A_site_125017
mod ID: M6ASITE002925 Click to Show/Hide the Full List
mod site chr11:216656-216657:- [3]
Sequence AATAAATGGTAACATAGGAGACATCCACATCCCAATTCTGA
Motif Score 2.897386905
Cell/Tissue List HeLa; HepG2; HEK293T; A549; U2OS; H1B; H1A; hNPCs; fibroblasts; GM12878; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000529937.1; ENST00000532837.5; ENST00000529382.5; ENST00000525319.5; ENST00000382743.9; ENST00000532956.5; ENST00000524564.5
External Link RMBase: m6A_site_125018
mod ID: M6ASITE002926 Click to Show/Hide the Full List
mod site chr11:216704-216705:- [3]
Sequence ATTCCAGCTTGATGGACCAGACAAATAGGATGATGGCTGCC
Motif Score 2.897386905
Cell/Tissue List HeLa; HepG2; HEK293T; hESC-HEK293T; A549; GM12878; MM6; Huh7; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; endometrial; HEC-1-A; NB4
Seq Type List m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List ENST00000532837.5; ENST00000382743.9; ENST00000529937.1; ENST00000529382.5; ENST00000524564.5; ENST00000532956.5; ENST00000525319.5
External Link RMBase: m6A_site_125019
mod ID: M6ASITE002927 Click to Show/Hide the Full List
mod site chr11:216709-216710:- [3]
Sequence TCTGTATTCCAGCTTGATGGACCAGACAAATAGGATGATGG
Motif Score 3.622404762
Cell/Tissue List HeLa; HepG2; HEK293T; A549; GM12878; MM6; Huh7; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; endometrial; HEC-1-A; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000524564.5; ENST00000382743.9; ENST00000532837.5; ENST00000532956.5; ENST00000525319.5; ENST00000529937.1; ENST00000529382.5
External Link RMBase: m6A_site_125020
mod ID: M6ASITE002928 Click to Show/Hide the Full List
mod site chr11:218811-218812:- [3]
Sequence GGTACAGACTGCTGAGGAGGACCATCCAAGGGGCTGCCCTT
Motif Score 3.622404762
Cell/Tissue List HeLa; HepG2; HEK293T; U2OS; GM12878; A549; MM6; Huh7; peripheral-blood; GSC-11; HEK293A-TOA; TREX; endometrial; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000524564.5; ENST00000532837.5; ENST00000529382.5; ENST00000382743.9; ENST00000532956.5; ENST00000525319.5; ENST00000529937.1
External Link RMBase: m6A_site_125021
mod ID: M6ASITE002929 Click to Show/Hide the Full List
mod site chr11:218824-218825:- [3]
Sequence GGGAAACTGGGAAGGTACAGACTGCTGAGGAGGACCATCCA
Motif Score 3.319380952
Cell/Tissue List HeLa; HepG2; U2OS; GM12878; A549; MM6; peripheral-blood; GSC-11; HEK293A-TOA; TREX; endometrial; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000524564.5; ENST00000532837.5; ENST00000529937.1; ENST00000382743.9; ENST00000525319.5; ENST00000532956.5; ENST00000529382.5
External Link RMBase: m6A_site_125022
mod ID: M6ASITE002930 Click to Show/Hide the Full List
mod site chr11:218839-218840:- [3]
Sequence GGGACCTTGTGCAGCGGGAAACTGGGAAGGTACAGACTGCT
Motif Score 2.627720238
Cell/Tissue List HeLa; HepG2; U2OS; GM12878; A549; MM6; peripheral-blood; GSC-11; HEK293A-TOA; TREX; endometrial; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000532956.5; ENST00000532837.5; ENST00000525319.5; ENST00000529382.5; ENST00000529937.1; ENST00000524564.5; ENST00000382743.9
External Link RMBase: m6A_site_125023
mod ID: M6ASITE002931 Click to Show/Hide the Full List
mod site chr11:218856-218857:- [3]
Sequence CTGGACAGAAGAGATGCGGGACCTTGTGCAGCGGGAAACTG
Motif Score 3.622404762
Cell/Tissue List HeLa; HepG2; GM12878; A549; MM6; peripheral-blood; GSC-11; HEK293A-TOA; TREX; endometrial; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000525319.5; ENST00000382743.9; ENST00000529937.1; ENST00000524564.5; ENST00000532956.5; ENST00000529382.5; ENST00000532837.5
External Link RMBase: m6A_site_125024
mod ID: M6ASITE002932 Click to Show/Hide the Full List
mod site chr11:218872-218873:- [3]
Sequence TAGTGGAGCTTCTGGGCTGGACAGAAGAGATGCGGGACCTT
Motif Score 3.643047619
Cell/Tissue List HeLa; HepG2; GM12878; A549; MM6; peripheral-blood; GSC-11; HEK293A-TOA; TREX; endometrial; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000524564.5; ENST00000532837.5; ENST00000525319.5; ENST00000532956.5; ENST00000529937.1; ENST00000529382.5; ENST00000382743.9
External Link RMBase: m6A_site_125025
mod ID: M6ASITE002933 Click to Show/Hide the Full List
mod site chr11:218973-218974:- [3]
Sequence CCGACTGCTCATCAACCGGGACTTGGTGGGGCCCTTGGCTT
Motif Score 4.065041667
Cell/Tissue List HeLa; HEK293A-TOA; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000382743.9; ENST00000529937.1; ENST00000532837.5; ENST00000524564.5; ENST00000529382.5; ENST00000532956.5; ENST00000525319.5
External Link RMBase: m6A_site_125026
mod ID: M6ASITE002934 Click to Show/Hide the Full List
mod site chr11:222443-222444:- [3]
Sequence GAGGCCGTGGATTCCCAAGGACCCCAGGGCTGTGGCTGGAG
Motif Score 3.622404762
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000382743.9; ENST00000529382.5; ENST00000529937.1; ENST00000532956.5; ENST00000532837.5; ENST00000525319.5; ENST00000524564.5
External Link RMBase: m6A_site_125027
mod ID: M6ASITE002935 Click to Show/Hide the Full List
mod site chr11:224088-224089:- [3]
Sequence ATCTGCTGCTCATCCTTGGGACCTCCCTGGAGGTTTGTCAG
Motif Score 3.622404762
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000524564.5; ENST00000529937.1; ENST00000382743.9; ENST00000532837.5; ENST00000532956.5; ENST00000529382.5; ENST00000525319.5
External Link RMBase: m6A_site_125028
mod ID: M6ASITE002936 Click to Show/Hide the Full List
mod site chr11:233002-233003:- [5]
Sequence TCTGCGGCTCTACACGCAGAACATCGATGGGCTTGAGAGAG
Motif Score 2.951386905
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000529055.5; ENST00000531753.5; ENST00000526854.5; ENST00000528469.1; ENST00000529937.1; ENST00000529382.5; ENST00000532956.5; ENST00000530067.1; ENST00000382743.9; ENST00000532837.5; ENST00000524564.5; ENST00000528702.5; ENST00000525319.5
External Link RMBase: m6A_site_125029
mod ID: M6ASITE002937 Click to Show/Hide the Full List
mod site chr11:233035-233036:- [5]
Sequence CTTTCTCCGGCTGCTTCATGACAAGGGGCTGCTTCTGCGGC
Motif Score 2.859755952
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000528702.5; ENST00000532956.5; ENST00000525319.5; ENST00000524564.5; ENST00000531753.5; ENST00000529382.5; ENST00000529937.1; ENST00000528469.1; ENST00000526854.5; ENST00000532837.5; ENST00000382743.9; ENST00000529055.5; ENST00000530067.1
External Link RMBase: m6A_site_125030
mod ID: M6ASITE002938 Click to Show/Hide the Full List
mod site chr11:233077-233078:- [5]
Sequence GGAGCTGTACCCTGGAAACTACAAGCCCAACGTCACTCACT
Motif Score 2.078666667
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000531753.5; ENST00000528469.1; ENST00000529382.5; ENST00000382743.9; ENST00000528702.5; ENST00000526854.5; ENST00000532837.5; ENST00000529055.5; ENST00000532956.5; ENST00000529937.1; ENST00000530067.1; ENST00000525319.5; ENST00000524564.5
External Link RMBase: m6A_site_125031
mod ID: M6ASITE002939 Click to Show/Hide the Full List
mod site chr11:233080-233081:- [8]
Sequence CAAGGAGCTGTACCCTGGAAACTACAAGCCCAACGTCACTC
Motif Score 2.627720238
Cell/Tissue List MT4
Seq Type List MeRIP-seq
Transcript ID List ENST00000529382.5; ENST00000526854.5; ENST00000529055.5; ENST00000524564.5; ENST00000530067.1; ENST00000532837.5; ENST00000382743.9; ENST00000529937.1; ENST00000532956.5; ENST00000528469.1; ENST00000531753.5; ENST00000525319.5; ENST00000528702.5
External Link RMBase: m6A_site_125032
mod ID: M6ASITE002940 Click to Show/Hide the Full List
mod site chr11:233128-233129:- [5]
Sequence TGAACTCCCATTCTTCTTTCACAACCCCAAGCCCTTTTTCA
Motif Score 2.047297619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000531753.5; ENST00000530067.1; ENST00000532956.5; ENST00000532837.5; ENST00000529382.5; ENST00000529055.5; ENST00000529937.1; ENST00000526854.5; ENST00000528702.5; ENST00000525319.5; ENST00000524564.5; ENST00000382743.9; ENST00000528469.1
External Link RMBase: m6A_site_125033
mod ID: M6ASITE002941 Click to Show/Hide the Full List
mod site chr11:233145-233146:- [8]
Sequence TACCCCGAGGCCATTTTTGAACTCCCATTCTTCTTTCACAA
Motif Score 3.373380952
Cell/Tissue List MT4
Seq Type List MeRIP-seq
Transcript ID List ENST00000525319.5; ENST00000532837.5; ENST00000524564.5; ENST00000529937.1; ENST00000528702.5; ENST00000526854.5; ENST00000532956.5; ENST00000529055.5; ENST00000529382.5; ENST00000382743.9; ENST00000528469.1; ENST00000530067.1; ENST00000531753.5
External Link RMBase: m6A_site_125034
mod ID: M6ASITE002942 Click to Show/Hide the Full List
mod site chr11:233164-233165:- [6]
Sequence CCAGCAGTACGATCTCCCGTACCCCGAGGCCATTTTTGAAC
Motif Score 2.8355
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000532956.5; ENST00000528469.1; ENST00000532837.5; ENST00000524564.5; ENST00000528702.5; ENST00000382743.9; ENST00000529382.5; ENST00000529937.1; ENST00000526854.5; ENST00000525319.5; ENST00000529055.5; ENST00000531753.5; ENST00000530067.1
External Link RMBase: m6A_site_125035
mod ID: M6ASITE002943 Click to Show/Hide the Full List
mod site chr11:233348-233349:- [8]
Sequence CACACCCAGTGGCATTCCAGACTTCAGGTACTGCCCACAGT
Motif Score 3.319380952
Cell/Tissue List MT4; Huh7
Seq Type List MeRIP-seq
Transcript ID List ENST00000528702.5; ENST00000530067.1; ENST00000526854.5; ENST00000529937.1; ENST00000524564.5; ENST00000525776.1; ENST00000528469.1; ENST00000529382.5; ENST00000529055.5; ENST00000532956.5; ENST00000531753.5; ENST00000382743.9; ENST00000525237.1; ENST00000525319.5; ENST00000532837.5
External Link RMBase: m6A_site_125036
mod ID: M6ASITE002944 Click to Show/Hide the Full List
mod site chr11:233367-233368:- [4]
Sequence TGGTGGGGGCCGGCATCAGCACACCCAGTGGCATTCCAGAC
Motif Score 2.830589286
Cell/Tissue List kidney; hESC-HEK293T
Seq Type List m6A-REF-seq; MAZTER-seq
Transcript ID List ENST00000382743.9; ENST00000528702.5; ENST00000529382.5; ENST00000532956.5; ENST00000525776.1; ENST00000524564.5; ENST00000529937.1; ENST00000532837.5; ENST00000530067.1; ENST00000525237.1; ENST00000528469.1; ENST00000526854.5; ENST00000529055.5; ENST00000531753.5; ENST00000525319.5
External Link RMBase: m6A_site_125037
mod ID: M6ASITE002945 Click to Show/Hide the Full List
mod site chr11:233459-233460:- [5]
Sequence TGGAAGTGGAGGCAGCAGTGACAAGGGGAAGCTTTCCCTGC
Motif Score 2.859755952
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000525776.1; ENST00000529055.5; ENST00000529937.1; ENST00000382743.9; ENST00000525319.5; ENST00000530067.1; ENST00000528469.1; ENST00000524564.5; ENST00000528702.5; ENST00000532956.5; ENST00000526854.5; ENST00000532837.5; ENST00000531753.5; ENST00000529382.5; ENST00000525237.1
External Link RMBase: m6A_site_125038
mod ID: M6ASITE002946 Click to Show/Hide the Full List
mod site chr11:236112-236113:- [3]
Sequence CCCTTGCAGAGGCCTCCCAGACCCGAGGTGCCCAGGGCATT
Motif Score 2.876744048
Cell/Tissue List HeLa; HEK293T
Seq Type List m6A-seq
Transcript ID List ENST00000529382.5; ENST00000524564.5; ENST00000382743.9; ENST00000529055.5; ENST00000528469.1; ENST00000532956.5; ENST00000530067.1; ENST00000525319.5; ENST00000529937.1; ENST00000528702.5; ENST00000525237.1; ENST00000532837.5; ENST00000526854.5
External Link RMBase: m6A_site_125039
mod ID: M6ASITE002947 Click to Show/Hide the Full List
mod site chr11:236143-236144:- [3]
Sequence GGCCCGCGGTGAGCCCTTGGACCCGGCGCGCCCCTTGCAGA
Motif Score 3.622404762
Cell/Tissue List HeLa; HEK293T; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000524564.5; ENST00000529937.1; ENST00000529382.5; ENST00000382743.9; ENST00000525237.1; ENST00000532956.5; ENST00000528469.1; ENST00000529055.5; ENST00000525319.5; ENST00000530067.1; ENST00000526854.5; ENST00000532837.5; ENST00000528702.5
External Link RMBase: m6A_site_125040
mod ID: M6ASITE002948 Click to Show/Hide the Full List
mod site chr11:236329-236330:- [3]
Sequence GACTCCTTGGACTGCGCGGAACATGGCGTTCTGGGGTTGGC
Motif Score 2.951386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000529937.1; ENST00000529055.5; ENST00000532837.5; ENST00000525319.5; ENST00000524564.5; ENST00000382743.9; ENST00000526854.5; ENST00000529382.5; ENST00000532956.5; ENST00000530067.1; ENST00000528702.5; ENST00000528469.1
External Link RMBase: m6A_site_125041
mod ID: M6ASITE002949 Click to Show/Hide the Full List
mod site chr11:236339-236340:- [3]
Sequence GAGTCCGGAGGACTCCTTGGACTGCGCGGAACATGGCGTTC
Motif Score 4.065041667
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000528469.1; ENST00000528702.5; ENST00000532956.5; ENST00000524564.5; ENST00000532837.5; ENST00000525319.5; ENST00000382743.9; ENST00000529382.5; ENST00000530067.1
External Link RMBase: m6A_site_125042
mod ID: M6ASITE002950 Click to Show/Hide the Full List
mod site chr11:236348-236349:- [3]
Sequence GGGCGGGGCGAGTCCGGAGGACTCCTTGGACTGCGCGGAAC
Motif Score 4.065041667
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000529382.5; ENST00000525319.5; ENST00000524564.5; ENST00000528469.1; ENST00000532956.5; ENST00000528702.5
External Link RMBase: m6A_site_125043