Epigenetic Target Information

General Information of the Epigenetic Target (ID: EPITAR00525)

Target Name	Proliferation-associated protein 2G4 (PA2G4)
Synonyms	Cell cycle protein p38-2G4 homolog; hG4-1; ErbB3-binding protein 1 Click to Show/Hide
Gene Name	PA2G4
Sequence	MSGEDEQQEQTIAEDLVVTKYKMGGDIANRVLRSLVEASSSGVSVLSLCEKGDAMIMEETGKIFKKEKEMKKGIAFPTSISVNNCVCHFSPLKSDQDYILKEGDLVKIDLGVHVDGFIANVAHTFVVDVAQGTQVTGRKADVIKAAHLCAEAALRLVKPGNQNTQVTEAWNKVAHSFNCTPIEGMLSHQLKQHVIDGEKTIIQNPTDQQKKDHEKAEFEVHEVYAVDVLVSSGEGKAKDAGQRTTIYKRDPSKQYGLKMKTSRAFFSEVERRFDAMPFTLRAFEDEKKARMGVVECAKHELLQPFNVLYEKEGEFVAQFKFTVLLMPNGPMRITSGPFEPDLYKSEMEVQDAELKALLQSSASRKTQKKKKKKASKTAENATSGETLEENEAGD Click to Show/Hide
Family	Peptidase M24 family
Function	May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor (AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin (HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase (HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs (internal ribosomal entry site) (By similarity). Regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation (By similarity). Click to Show/Hide
Gene ID	5036
HGNC ID	HGNC:8550
Ensembl Gene ID	ENSG00000170515
KEGG ID	hsa:5036
Chromosomal Location	12q13.2

RNA Modification Sequencing Data Associated with the Target (ID: EPITAR00525)

Proliferation-associated protein 2G4 (PA2G4)

N4-acetylcytidine (ac4C)

In total 2 m6A sequence/site(s) in this target gene
mod ID: AC4SITE000178		Click to Show/Hide the Full List
mod site	chr12:56104741-56104742:+		[1]
Sequence	TGGTGGTAGTAGGAAGATGTCGGGCGAGGACGAGCAACAGG
Cell/Tissue List	H1
Seq Type List	ac4C-seq
Transcript ID List	ENST00000548861.1; ENST00000552766.5; ENST00000303305.11
External Link	RMBase: ac4C_site_430
mod ID: AC4SITE000179		Click to Show/Hide the Full List
mod site	chr12:56112975-56112976:+
Sequence	GAAGTGCAGTTCTTCTCCACCTAGGACCGCCAGCAGAGCGG
Cell/Tissue List	DLD1
Seq Type List	acRIP-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11
External Link	RMBase: ac4C_site_431

2'-O-Methylation (2'-O-Me)

In total 3 m6A sequence/site(s) in this target gene
mod ID: 2OMSITE000066		Click to Show/Hide the Full List
mod site	chr12:56104654-56104655:+		[2]
Sequence	CCTCGAGGATCGAGGGGACTCTGACCACAGCCTGTGGCTGG
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000548861.1; ENST00000552766.5; ENST00000303305.11
External Link	RMBase: Nm_site_1368
mod ID: 2OMSITE000065		Click to Show/Hide the Full List
mod site	chr12:56104653-56104654:+		[2]
Sequence	TCCTCGAGGATCGAGGGGACTCTGACCACAGCCTGTGGCTG
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11; ENST00000548861.1
External Link	RMBase: Nm_site_1367
mod ID: 2OMSITE000067		Click to Show/Hide the Full List
mod site	chr12:56104655-56104656:+		[2]
Sequence	CTCGAGGATCGAGGGGACTCTGACCACAGCCTGTGGCTGGG
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000548861.1; ENST00000552766.5; ENST00000303305.11
External Link	RMBase: Nm_site_1369

5-methylcytidine (m5C)

In total 6 m6A sequence/site(s) in this target gene
mod ID: M5CSITE000050		Click to Show/Hide the Full List
mod site	chr12:56112905-56112906:+
Sequence	TGAGGTGGGTCCCATCTCCCCAGCTTGCTGCTCCTGCCTCA
Cell/Tissue List	testis
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m5C_site_10333
mod ID: M5CSITE000051		Click to Show/Hide the Full List
mod site	chr12:56113009-56113010:+		[3]
Sequence	AGAGCGGGGGGATCTCCCTGCCCCCACCCCAGTTCCCCAAC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m5C_site_10334
mod ID: M5CSITE000052		Click to Show/Hide the Full List
mod site	chr12:56113010-56113011:+		[3]
Sequence	GAGCGGGGGGATCTCCCTGCCCCCACCCCAGTTCCCCAACC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m5C_site_10335
mod ID: M5CSITE000053		Click to Show/Hide the Full List
mod site	chr12:56113011-56113012:+		[3]
Sequence	AGCGGGGGGATCTCCCTGCCCCCACCCCAGTTCCCCAACCC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m5C_site_10336
mod ID: M5CSITE000054		Click to Show/Hide the Full List
mod site	chr12:56113012-56113013:+		[3]
Sequence	GCGGGGGGATCTCCCTGCCCCCACCCCAGTTCCCCAACCCA
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m5C_site_10337
mod ID: M5CSITE000055		Click to Show/Hide the Full List
mod site	chr12:56113013-56113014:+		[3]
Sequence	CGGGGGGATCTCCCTGCCCCCACCCCAGTTCCCCAACCCAC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m5C_site_10338

N6-methyladenosine (m6A)

In total 51 m6A sequence/site(s) in this target gene
mod ID: M6ASITE013294		Click to Show/Hide the Full List
mod site	chr12:56104651-56104652:+		[4]
Sequence	TCTCCTCGAGGATCGAGGGGACTCTGACCACAGCCTGTGGC
Motif Score	4.065041667
Cell/Tissue List	HeLa; CD34; HepG2; A549; HEK293T; H1A; MT4; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11; ENST00000548861.1
External Link	RMBase: m6A_site_192524
mod ID: M6ASITE013295		Click to Show/Hide the Full List
mod site	chr12:56104683-56104684:+		[4]
Sequence	GCCTGTGGCTGGGAAGGGAGACAGAGGCGGCGGCGGCTCAG
Motif Score	2.897386905
Cell/Tissue List	HeLa; CD34; HepG2; A549; MT4; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11; ENST00000548861.1
External Link	RMBase: m6A_site_192525
mod ID: M6ASITE013296		Click to Show/Hide the Full List
mod site	chr12:56104767-56104768:+		[4]
Sequence	AGGACGAGCAACAGGAGCAAACTATCGCTGAGGACCTGGTC
Motif Score	2.627720238
Cell/Tissue List	HeLa; CD34; HepG2; A549; MT4; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; MSC; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000552766.5; ENST00000548861.1; ENST00000303305.11
External Link	RMBase: m6A_site_192526
mod ID: M6ASITE013297		Click to Show/Hide the Full List
mod site	chr12:56104780-56104781:+		[4]
Sequence	GGAGCAAACTATCGCTGAGGACCTGGTCGTGACCAAGTATA
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34; HepG2; A549; MT4; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; MSC; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000548861.1; ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m6A_site_192527
mod ID: M6ASITE013298		Click to Show/Hide the Full List
mod site	chr12:56104813-56104814:+		[5]
Sequence	CAAGTATAAGATGGGGGGCGACATCGCCAACAGTGAGTGCG
Motif Score	2.865571429
Cell/Tissue List	kidney; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000548861.1; ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192528
mod ID: M6ASITE013299		Click to Show/Hide the Full List
mod site	chr12:56104969-56104970:+		[4]
Sequence	GGGCACGGCGTGGTGGGAAGACCCGGTGTCGCGCCTGGGAC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11; ENST00000548861.1; ENST00000553057.5
External Link	RMBase: m6A_site_192529
mod ID: M6ASITE013300		Click to Show/Hide the Full List
mod site	chr12:56104988-56104989:+		[4]
Sequence	GACCCGGTGTCGCGCCTGGGACCTGAGCGGGCAGGCCCAGG
Motif Score	3.622404762
Cell/Tissue List	HeLa; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000552766.5; ENST00000548861.1; ENST00000303305.11; ENST00000553057.5
External Link	RMBase: m6A_site_192530
mod ID: M6ASITE013301		Click to Show/Hide the Full List
mod site	chr12:56105060-56105061:+		[4]
Sequence	AGGATGAGCGCAGAGAGGGGACCCTGGCAGGCTCCGACCCG
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000548861.1; ENST00000552766.5; ENST00000303305.11; ENST00000553057.5
External Link	RMBase: m6A_site_192531
mod ID: M6ASITE013302		Click to Show/Hide the Full List
mod site	chr12:56106676-56106677:+		[4]
Sequence	ATGCCATGATTATGGAAGAAACAGGGAAAATCTTCAAGAAA
Motif Score	2.20572619
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000303305.11; ENST00000551061.1; ENST00000553057.5; ENST00000552766.5; ENST00000548861.1
External Link	RMBase: m6A_site_192532
mod ID: M6ASITE013303		Click to Show/Hide the Full List
mod site	chr12:56107022-56107023:+		[6]
Sequence	CACCAGCATTTCGGTAAATAACTGTGTATGTCACTTCTCCC
Motif Score	2.590089286
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000552766.5; ENST00000550166.1; ENST00000548861.1; ENST00000551061.1; ENST00000553057.5; ENST00000303305.11
External Link	RMBase: m6A_site_192533
mod ID: M6ASITE013304		Click to Show/Hide the Full List
mod site	chr12:56107230-56107231:+		[7]
Sequence	CTTCATCGCTAATGTAGCTCACACTTTTGTGGTTGATGTAG
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000550166.1; ENST00000553057.5; ENST00000552766.5; ENST00000303305.11; ENST00000548861.1
External Link	RMBase: m6A_site_192534
mod ID: M6ASITE013305		Click to Show/Hide the Full List
mod site	chr12:56107523-56107524:+		[4]
Sequence	CATGTCCTTATCTACAGGGGACCCAAGTAACAGGGAGGAAA
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000552766.5; ENST00000553057.5; ENST00000550166.1; ENST00000303305.11; ENST00000548861.1
External Link	RMBase: m6A_site_192535
mod ID: M6ASITE013306		Click to Show/Hide the Full List
mod site	chr12:56109230-56109231:+		[7]
Sequence	TTTGATGTTGTACTTCTAGAACACACAAGTGACAGAAGCCT
Motif Score	2.951386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000548861.1; ENST00000303305.11; ENST00000550166.1; ENST00000553057.5; ENST00000552766.5
External Link	RMBase: m6A_site_192536
mod ID: M6ASITE013307		Click to Show/Hide the Full List
mod site	chr12:56109254-56109255:+		[7]
Sequence	ACAAGTGACAGAAGCCTGGAACAAAGTTGCCCACTCATTTA
Motif Score	2.951386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000552766.5; ENST00000550166.1; ENST00000303305.11; ENST00000548861.1; ENST00000553057.5
External Link	RMBase: m6A_site_192537
mod ID: M6ASITE013308		Click to Show/Hide the Full List
mod site	chr12:56109866-56109867:+		[7]
Sequence	CTATCTACAGGTATGCTGTCACACCAGTTGAAGCAGCATGT
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000550166.1; ENST00000553057.5; ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192538
mod ID: M6ASITE013309		Click to Show/Hide the Full List
mod site	chr12:56110428-56110429:+		[7]
Sequence	GAAAAAGCTGAATTTGAGGTACATGAAGTATATGCTGTGGA
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11; ENST00000552528.1
External Link	RMBase: m6A_site_192539
mod ID: M6ASITE013310		Click to Show/Hide the Full List
mod site	chr12:56110589-56110590:+		[6]
Sequence	AGGACAGAGAACCACTATTTACAAACGAGACCCCTCTAAAC
Motif Score	2.07285119
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000303305.11; ENST00000552528.1; ENST00000552766.5; ENST00000552266.1
External Link	RMBase: m6A_site_192540
mod ID: M6ASITE013311		Click to Show/Hide the Full List
mod site	chr12:56110617-56110618:+		[6]
Sequence	GACCCCTCTAAACAGTATGGACTGAAAATGAAAACTTCACG
Motif Score	4.065041667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000552528.1; ENST00000552266.1; ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192541
mod ID: M6ASITE013312		Click to Show/Hide the Full List
mod site	chr12:56111014-56111015:+		[7]
Sequence	GGTGTGGTGGAGTGCGCCAAACATGAACTGCTGCAACCATT
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000552266.1; ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m6A_site_192542
mod ID: M6ASITE013313		Click to Show/Hide the Full List
mod site	chr12:56111020-56111021:+		[6]
Sequence	GTGGAGTGCGCCAAACATGAACTGCTGCAACCATTTAATGT
Motif Score	3.373380952
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000552266.1; ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192543
mod ID: M6ASITE013314		Click to Show/Hide the Full List
mod site	chr12:56111271-56111272:+		[7]
Sequence	TCCCTTCGAGCCTGACCTCTACAAGTCTGAGATGGAGGTCC
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000552266.1; ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192544
mod ID: M6ASITE013315		Click to Show/Hide the Full List
mod site	chr12:56111505-56111506:+		[4]
Sequence	AGAGTTCTGCAAGTCGAAAAACCCAGAAAAAGAAAAAAAAG
Motif Score	2.185083333
Cell/Tissue List	HeLa; CD34; HepG2; MM6; Huh7; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11; ENST00000552266.1
External Link	RMBase: m6A_site_192545
mod ID: M6ASITE013316		Click to Show/Hide the Full List
mod site	chr12:56112831-56112832:+		[4]
Sequence	CTTGCATATAGGCCTCCAAGACTGCAGAGAATGCCACCAGT
Motif Score	3.319380952
Cell/Tissue List	HeLa; CD34; HepG2; H1299; MM6; Huh7; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192546
mod ID: M6ASITE013317		Click to Show/Hide the Full List
mod site	chr12:56112858-56112859:+		[4]
Sequence	AGAATGCCACCAGTGGGGAAACATTAGAAGAAAATGAAGCT
Motif Score	2.20572619
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; hESC-HEK293T; hNPCs; H1299; MM6; Huh7; endometrial; NB4
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m6A_site_192547
mod ID: M6ASITE013318		Click to Show/Hide the Full List
mod site	chr12:56112883-56112884:+		[4]
Sequence	AGAAGAAAATGAAGCTGGGGACTGAGGTGGGTCCCATCTCC
Motif Score	4.065041667
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; hNPCs; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192548
mod ID: M6ASITE013319		Click to Show/Hide the Full List
mod site	chr12:56112941-56112942:+		[4]
Sequence	CCTCATCCCCTTCCCACCAAACCCCAGACTCTGTGAAGTGC
Motif Score	2.185083333
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; hNPCs; fibroblasts; A549; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; iSLK; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192549
mod ID: M6ASITE013320		Click to Show/Hide the Full List
mod site	chr12:56112948-56112949:+		[4]
Sequence	CCCTTCCCACCAAACCCCAGACTCTGTGAAGTGCAGTTCTT
Motif Score	3.319380952
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; hNPCs; fibroblasts; A549; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; iSLK; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192550
mod ID: M6ASITE013321		Click to Show/Hide the Full List
mod site	chr12:56112980-56112981:+		[4]
Sequence	GCAGTTCTTCTCCACCTAGGACCGCCAGCAGAGCGGGGGGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; hNPCs; fibroblasts; A549; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; iSLK; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192551
mod ID: M6ASITE013322		Click to Show/Hide the Full List
mod site	chr12:56113043-56113044:+		[7]
Sequence	CCCCAACCCACTCCCTTCCAACAACAACCAGCTCCAACTGA
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m6A_site_192552
mod ID: M6ASITE013323		Click to Show/Hide the Full List
mod site	chr12:56113046-56113047:+		[7]
Sequence	CAACCCACTCCCTTCCAACAACAACCAGCTCCAACTGACTC
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m6A_site_192553
mod ID: M6ASITE013324		Click to Show/Hide the Full List
mod site	chr12:56113063-56113064:+		[6]
Sequence	ACAACAACCAGCTCCAACTGACTCTGGTCTTGGGAGGTGAG
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192554
mod ID: M6ASITE013325		Click to Show/Hide the Full List
mod site	chr12:56113102-56113103:+		[4]
Sequence	AGGCTTCCCAACCACGGAAGACTACTTTAAATGAAAAAAAG
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; hNPCs; fibroblasts; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; iSLK; endometrial; HEC-1-A; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; miCLIP
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192555
mod ID: M6ASITE013326		Click to Show/Hide the Full List
mod site	chr12:56113105-56113106:+		[6]
Sequence	CTTCCCAACCACGGAAGACTACTTTAAATGAAAAAAAGAAA
Motif Score	2.500660714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192556
mod ID: M6ASITE013327		Click to Show/Hide the Full List
mod site	chr12:56113188-56113189:+		[6]
Sequence	CCCTCTTTCTAGCCTTTTCTACTACTCTCTGCTTGGTCAAG
Motif Score	2.500660714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192557
mod ID: M6ASITE013328		Click to Show/Hide the Full List
mod site	chr12:56113228-56113229:+		[4]
Sequence	GGTTTGTGCCCCACTACAGAACAGGGCTAAATTAGCCACCA
Motif Score	2.951386905
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192558
mod ID: M6ASITE013329		Click to Show/Hide the Full List
mod site	chr12:56113258-56113259:+		[4]
Sequence	ATTAGCCACCACCACTGAAAACTCAGCCGAATTTTTTTATA
Motif Score	2.627720238
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m6A_site_192559
mod ID: M6ASITE013330		Click to Show/Hide the Full List
mod site	chr12:56113535-56113536:+		[6]
Sequence	ATCTTTTTTCTTCCATTTTCACAAAGCTGTAAAGAAATAAT
Motif Score	2.047297619
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m6A_site_192560
mod ID: M6ASITE013331		Click to Show/Hide the Full List
mod site	chr12:56113614-56113615:+		[6]
Sequence	GTCTTTCCTCGCTCCATCTTACACAGACCTGAGCTGGAAGC
Motif Score	2.07285119
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192561
mod ID: M6ASITE013332		Click to Show/Hide the Full List
mod site	chr12:56113616-56113617:+		[6]
Sequence	CTTTCCTCGCTCCATCTTACACAGACCTGAGCTGGAAGCTC
Motif Score	2.084928571
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m6A_site_192562
mod ID: M6ASITE013333		Click to Show/Hide the Full List
mod site	chr12:56113620-56113621:+		[4]
Sequence	CCTCGCTCCATCTTACACAGACCTGAGCTGGAAGCTCAACT
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; HEK293T; HepG2; hESCs; fibroblasts; A549; GM12878; iSLK; MSC; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m6A_site_192563
mod ID: M6ASITE013334		Click to Show/Hide the Full List
mod site	chr12:56113638-56113639:+		[6]
Sequence	AGACCTGAGCTGGAAGCTCAACTGGTTTTGTTCCCTGTTTG
Motif Score	2.595904762
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m6A_site_192564
mod ID: M6ASITE013335		Click to Show/Hide the Full List
mod site	chr12:56113691-56113692:+		[4]
Sequence	CTCCCTCCCATGAAAGAAAAACCAAGAACCAGAGGCGTAGA
Motif Score	2.185083333
Cell/Tissue List	HeLa; CD34; HEK293T; A549; HepG2; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m6A_site_192568
mod ID: M6ASITE013336		Click to Show/Hide the Full List
mod site	chr12:56113698-56113699:+		[4]
Sequence	CCATGAAAGAAAAACCAAGAACCAGAGGCGTAGACTGACTG
Motif Score	2.930744048
Cell/Tissue List	HeLa; CD34; HEK293T; A549; HepG2; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; CD8T; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m6A_site_192569
mod ID: M6ASITE013337		Click to Show/Hide the Full List
mod site	chr12:56113711-56113712:+		[4]
Sequence	ACCAAGAACCAGAGGCGTAGACTGACTGAAGACACAACTCC
Motif Score	3.319380952
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; MM6; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m6A_site_192570
mod ID: M6ASITE013338		Click to Show/Hide the Full List
mod site	chr12:56113715-56113716:+		[6]
Sequence	AGAACCAGAGGCGTAGACTGACTGAAGACACAACTCCTGGC
Motif Score	3.28175
Cell/Tissue List	HEK293T; CD8T
Seq Type List	DART-seq; m6A-CLIP/IP
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192571
mod ID: M6ASITE013339		Click to Show/Hide the Full List
mod site	chr12:56113722-56113723:+		[4]
Sequence	GAGGCGTAGACTGACTGAAGACACAACTCCTGGCTTTCTGA
Motif Score	2.897386905
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; hESC-HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; MM6; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192572
mod ID: M6ASITE013340		Click to Show/Hide the Full List
mod site	chr12:56113751-56113752:+		[4]
Sequence	CTGGCTTTCTGAAGCTATGGACTTGGATTGGATTGCTGGGG
Motif Score	4.065041667
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; CD8T; H1299; MM6; Jurkat; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m6A_site_192573
mod ID: M6ASITE013341		Click to Show/Hide the Full List
mod site	chr12:56113789-56113790:+		[6]
Sequence	GGGGTTTGTAGAGAAAGGTGACAAATTTCAGTACCTCTGGC
Motif Score	2.859755952
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192575
mod ID: M6ASITE013342		Click to Show/Hide the Full List
mod site	chr12:56113825-56113826:+		[4]
Sequence	CTGGCATGCTGTCCCAGGAAACTAGGGCTCCCACTAACTTA
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Jurkat; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq; DART-seq
Transcript ID List	ENST00000552766.5; ENST00000303305.11
External Link	RMBase: m6A_site_192577
mod ID: M6ASITE013343		Click to Show/Hide the Full List
mod site	chr12:56113858-56113859:+		[4]
Sequence	CTAACTTATGAGGTTTTTAAACACATTGAAAATGACATGAC
Motif Score	2.20572619
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; hESC-HEK293T; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; H1299; MM6; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192579
mod ID: M6ASITE013344		Click to Show/Hide the Full List
mod site	chr12:56113877-56113878:+		[6]
Sequence	AACACATTGAAAATGACATGACATTAAAATAAATTTGGATT
Motif Score	2.859755952
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000303305.11; ENST00000552766.5
External Link	RMBase: m6A_site_192580

Ref 1	NAT10-mediated N4-acetylcytidine mRNA modification regulates self-renewal in human embryonic stem cells. Nucleic Acids Res. 2023 Sep 8;51(16):8514-8531. doi: 10.1093/nar/gkad628.
Ref 2	Nm-seq maps 2'-O-methylation sites in human mRNA with base precision. Nat Methods. 2017 Jul;14(7):695-698. doi: 10.1038/nmeth.4294. Epub 2017 May 15.
Ref 3	Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6784-6789. doi: 10.1073/pnas.1817334116. Epub 2019 Mar 14.
Ref 4	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 5	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 6	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 7	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.

Epigenetic Target Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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