Epigenetic Target Information

General Information of the Epigenetic Target (ID: EPITAR00510)
Target Name Ficolin-1 (FCN1)
Synonyms
Collagen/fibrinogen domain-containing protein 1; Ficolin-A; Ficolin-alpha; M-ficolin; FCNM
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Gene Name FCN1
Sequence
MELSGATMARGLAVLLVLFLHIKNLPAQAADTCPEVKVVGLEGSDKLTILRGCPGLPGAPGPKGEAGVIGERGERGLPGAPGKAGPVGPKGDRGEKGMRGEKGDAGQSQSCATGPRNCKDLLDRGYFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRMDGSVDFYRDWAAYKQGFGSQLGEFWLGNDNIHALTAQGSSELRVDLVDFEGNHQFAKYKSFKVADEAEKYKLVLGAFVGGSAGNSLTGHNNNFFSTKDQDNDVSSSNCAEKFQGAWWYADCHASNLNGLYLMGPHESYANGINWSAAKGYKYSYKVSEMKVRPA
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Family Ficolin lectin family
Function
Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8 (PubMed:21037097). Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage. {ECO:0000269|PubMed:20032467, ECO:0000269|PubMed:21037097}.
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Gene ID 2219
HGNC ID HGNC:3623
Ensembl Gene ID ENSG00000085265
KEGG ID hsa:2219
Chromosomal Location 9q34.3
RNA Modification Sequencing Data Associated with the Target (ID: EPITAR00510)
Ficolin-1 (FCN1)
Adenosine-to-Inosine editing (A-to-I)
In total 1 m6A sequence/site(s) in this target gene
mod ID: A2ISITE003290 Click to Show/Hide the Full List
mod site chr9:134906167-134906168:- [1]
Sequence TGGGTGGATCACTTGAGATCAGGAGTTCAAGACCAGCCTGG
Transcript ID List ENST00000371806.4; rmsk_2900150; ENST00000616356.4
External Link RMBase: RNA-editing_site_139006
N6-methyladenosine (m6A)
In total 37 m6A sequence/site(s) in this target gene
mod ID: M6ASITE090385 Click to Show/Hide the Full List
mod site chr9:134905261-134905262:- [2]
Sequence CAACATTTGGGCATTCGTGGACATCCACATAGTGTTGTTTC
Motif Score 3.643047619
Cell/Tissue List peripheral-blood; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4
External Link RMBase: m6A_site_846134
mod ID: M6ASITE090386 Click to Show/Hide the Full List
mod site chr9:134905318-134905319:- [3]
Sequence CTCTTCTTCCTGGCCATGGGACCTCTCAAGTAGGAGTGTAG
Motif Score 3.622404762
Cell/Tissue List CD4T; peripheral-blood; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4
External Link RMBase: m6A_site_846135
mod ID: M6ASITE090387 Click to Show/Hide the Full List
mod site chr9:134905417-134905418:- [2]
Sequence CCCCAACTCACATCAGCAGAACTGAGAGAGCTTTTGTGATT
Motif Score 3.373380952
Cell/Tissue List peripheral-blood; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4
External Link RMBase: m6A_site_846136
mod ID: M6ASITE090388 Click to Show/Hide the Full List
mod site chr9:134907739-134907740:- [3]
Sequence AAGGAGCATGAGTCTCACAAACATGGCAGCAAAAGGAGCCT
Motif Score 2.20572619
Cell/Tissue List CD4T; peripheral-blood
Seq Type List m6A-seq
Transcript ID List ENST00000616356.4; ENST00000371806.4; rmsk_2900154
External Link RMBase: m6A_site_846137
mod ID: M6ASITE090389 Click to Show/Hide the Full List
mod site chr9:134907873-134907874:- [3]
Sequence AATACTCACCATAGCACCAAACTGGAATCAGCCGACATACC
Motif Score 2.627720238
Cell/Tissue List CD4T
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4; rmsk_2900154; ENST00000616356.4
External Link RMBase: m6A_site_846138
mod ID: M6ASITE090390 Click to Show/Hide the Full List
mod site chr9:134907985-134907986:- [3]
Sequence ATCAACTGTTGGAGAAGAAGACACACAGTCCTCTAACCTGC
Motif Score 2.897386905
Cell/Tissue List CD4T
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4; rmsk_2900154; ENST00000616356.4
External Link RMBase: m6A_site_846139
mod ID: M6ASITE090391 Click to Show/Hide the Full List
mod site chr9:134908028-134908029:- [3]
Sequence TAACAATGCGAATTGATGGAACCAACCTGGAAAATGGCTTG
Motif Score 2.930744048
Cell/Tissue List CD4T
Seq Type List m6A-seq
Transcript ID List ENST00000616356.4; rmsk_2900154; ENST00000371806.4
External Link RMBase: m6A_site_846140
mod ID: M6ASITE090392 Click to Show/Hide the Full List
mod site chr9:134908531-134908532:- [3]
Sequence CCTGAGACTCATGGGATTAGACTAGGCCTACCTGGATGATC
Motif Score 3.319380952
Cell/Tissue List CD4T
Seq Type List m6A-seq
Transcript ID List ENST00000616356.4; ENST00000371806.4
External Link RMBase: m6A_site_846141
mod ID: M6ASITE090393 Click to Show/Hide the Full List
mod site chr9:134908545-134908546:- [3]
Sequence ACAGGGTCTCCACTCCTGAGACTCATGGGATTAGACTAGGC
Motif Score 3.319380952
Cell/Tissue List CD4T
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4; ENST00000616356.4
External Link RMBase: m6A_site_846142
mod ID: M6ASITE090394 Click to Show/Hide the Full List
mod site chr9:134908565-134908566:- [3]
Sequence CTCCCCCCAAGCCCCATGGGACAGGGTCTCCACTCCTGAGA
Motif Score 3.643047619
Cell/Tissue List CD4T
Seq Type List m6A-seq
Transcript ID List ENST00000616356.4; ENST00000371806.4
External Link RMBase: m6A_site_846143
mod ID: M6ASITE090395 Click to Show/Hide the Full List
mod site chr9:134908650-134908651:- [3]
Sequence ACTGGCATTCATTGGCCCGGACTCCTTCCCCCAACCCCAAA
Motif Score 4.065041667
Cell/Tissue List CD4T; peripheral-blood
Seq Type List m6A-seq
Transcript ID List ENST00000616356.4; ENST00000371806.4
External Link RMBase: m6A_site_846144
mod ID: M6ASITE090396 Click to Show/Hide the Full List
mod site chr9:134908704-134908705:- [3]
Sequence TTCCAGGGTTCTAGGGGAGAACCTGCTTCCTTGCCTTTTCC
Motif Score 2.930744048
Cell/Tissue List CD4T; peripheral-blood
Seq Type List m6A-seq
Transcript ID List ENST00000616356.4; ENST00000371806.4
External Link RMBase: m6A_site_846145
mod ID: M6ASITE090397 Click to Show/Hide the Full List
mod site chr9:134908743-134908744:- [3]
Sequence TTACTGGGCCAGCAGGCAGGACTCAGCAGTGGTGGCTCCTT
Motif Score 4.065041667
Cell/Tissue List CD4T
Seq Type List m6A-seq
Transcript ID List ENST00000616356.4; ENST00000371806.4
External Link RMBase: m6A_site_846146
mod ID: M6ASITE090398 Click to Show/Hide the Full List
mod site chr9:134908805-134908806:- [3]
Sequence AGTGGCTTGAAACAACAAGAACTCGCCACCTCCTGGCTCAG
Motif Score 3.373380952
Cell/Tissue List CD4T
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4; ENST00000616356.4
External Link RMBase: m6A_site_846147
mod ID: M6ASITE090399 Click to Show/Hide the Full List
mod site chr9:134908814-134908815:- [3]
Sequence CACAAATGGAGTGGCTTGAAACAACAAGAACTCGCCACCTC
Motif Score 2.20572619
Cell/Tissue List CD4T
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4; ENST00000616356.4
External Link RMBase: m6A_site_846148
mod ID: M6ASITE090400 Click to Show/Hide the Full List
mod site chr9:134908913-134908914:- [3]
Sequence TACCGAAGGACACTAAGGGAACCAAAGGAAGGCCAGAGGGG
Motif Score 2.930744048
Cell/Tissue List CD4T; peripheral-blood; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000616356.4; ENST00000371806.4; rmsk_2900156
External Link RMBase: m6A_site_846149
mod ID: M6ASITE090401 Click to Show/Hide the Full List
mod site chr9:134908924-134908925:- [3]
Sequence GAGCTCCCACTTACCGAAGGACACTAAGGGAACCAAAGGAA
Motif Score 3.643047619
Cell/Tissue List CD4T; peripheral-blood; NB4
Seq Type List m6A-seq
Transcript ID List rmsk_2900156; ENST00000616356.4; ENST00000371806.4
External Link RMBase: m6A_site_846150
mod ID: M6ASITE090402 Click to Show/Hide the Full List
mod site chr9:134909086-134909087:- [3]
Sequence TCAGCTAGAGGGGACCGCGGACCTCAGTGGGAAAAGCTGCA
Motif Score 3.622404762
Cell/Tissue List CD4T; peripheral-blood
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4; rmsk_2900156; ENST00000616356.4
External Link RMBase: m6A_site_846151
mod ID: M6ASITE090403 Click to Show/Hide the Full List
mod site chr9:134909093-134909094:- [3]
Sequence ACAGACCTCAGCTAGAGGGGACCGCGGACCTCAGTGGGAAA
Motif Score 3.622404762
Cell/Tissue List CD4T; peripheral-blood
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4; ENST00000616356.4; rmsk_2900156
External Link RMBase: m6A_site_846152
mod ID: M6ASITE090404 Click to Show/Hide the Full List
mod site chr9:134909109-134909110:- [3]
Sequence GGCCTTCCTCCCACACACAGACCTCAGCTAGAGGGGACCGC
Motif Score 2.876744048
Cell/Tissue List CD4T; peripheral-blood
Seq Type List m6A-seq
Transcript ID List rmsk_2900156; ENST00000616356.4; ENST00000371806.4
External Link RMBase: m6A_site_846153
mod ID: M6ASITE090405 Click to Show/Hide the Full List
mod site chr9:134909190-134909191:- [3]
Sequence TGGCTGCTGGGAAGAGATAAACACTTAGCACTCACTAAGTG
Motif Score 2.20572619
Cell/Tissue List CD4T; peripheral-blood
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4; ENST00000616356.4
External Link RMBase: m6A_site_846154
mod ID: M6ASITE090406 Click to Show/Hide the Full List
mod site chr9:134909255-134909256:- [3]
Sequence AGGGGGAAAGTTTAGTAGGAACTTTTCTGCTTCCCACCACG
Motif Score 3.373380952
Cell/Tissue List CD4T
Seq Type List m6A-seq
Transcript ID List ENST00000616356.4; ENST00000371806.4
External Link RMBase: m6A_site_846155
mod ID: M6ASITE090407 Click to Show/Hide the Full List
mod site chr9:134909288-134909289:- [3]
Sequence GTCACTTTGGGGTCCAGAAAACACTTACTAAAAAGGGGGAA
Motif Score 2.20572619
Cell/Tissue List CD4T
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4; ENST00000616356.4
External Link RMBase: m6A_site_846156
mod ID: M6ASITE090408 Click to Show/Hide the Full List
mod site chr9:134909592-134909593:- [3]
Sequence CTAAATATGTTTACTTTGGGACAGAAAAGTTTTACCAGTTT
Motif Score 3.643047619
Cell/Tissue List CD4T; peripheral-blood; endometrial; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000616356.4; ENST00000371806.4
External Link RMBase: m6A_site_846157
mod ID: M6ASITE090409 Click to Show/Hide the Full List
mod site chr9:134909705-134909706:- [4]
Sequence CACCCCATTTCCCCAGCCAGACACACTCCCATGACGCCCAC
Motif Score 2.897386905
Cell/Tissue List CD34; CD4T; peripheral-blood; endometrial; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000616356.4; ENST00000371806.4
External Link RMBase: m6A_site_846158
mod ID: M6ASITE090410 Click to Show/Hide the Full List
mod site chr9:134909786-134909787:- [4]
Sequence GCCCGCCTAGACGGGCCAGGACCCCTCCACATGCACCTGCT
Motif Score 3.622404762
Cell/Tissue List CD34; CD4T; peripheral-blood; endometrial; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4; ENST00000616356.4
External Link RMBase: m6A_site_846159
mod ID: M6ASITE090411 Click to Show/Hide the Full List
mod site chr9:134912571-134912572:- [2]
Sequence CTCTGTGGACTTCTATCGGGACTGGGCCGCATACAAGCAGG
Motif Score 4.065041667
Cell/Tissue List peripheral-blood; endometrial; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4; ENST00000616356.4
External Link RMBase: m6A_site_846160
mod ID: M6ASITE090412 Click to Show/Hide the Full List
mod site chr9:134912583-134912584:- [2]
Sequence GAGGATGGATGGCTCTGTGGACTTCTATCGGGACTGGGCCG
Motif Score 4.065041667
Cell/Tissue List peripheral-blood; endometrial; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000616356.4; ENST00000371806.4
External Link RMBase: m6A_site_846161
mod ID: M6ASITE090413 Click to Show/Hide the Full List
mod site chr9:134913017-134913018:- [3]
Sequence ACACGGACGGAGGGGGCTGGACCGTGAGTGTGGGGCTGGGC
Motif Score 3.622404762
Cell/Tissue List CD4T; peripheral-blood; endometrial; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4; ENST00000616356.4
External Link RMBase: m6A_site_846162
mod ID: M6ASITE090414 Click to Show/Hide the Full List
mod site chr9:134913037-134913038:- [3]
Sequence GACTGTGCTCTGTGACATGGACACGGACGGAGGGGGCTGGA
Motif Score 3.643047619
Cell/Tissue List CD4T; peripheral-blood; endometrial; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4; ENST00000616356.4
External Link RMBase: m6A_site_846163
mod ID: M6ASITE090415 Click to Show/Hide the Full List
mod site chr9:134913115-134913116:- [3]
Sequence CAACTGCAAGGACCTGCTAGACCGGGGGTATTTCCTGAGCG
Motif Score 2.876744048
Cell/Tissue List CD4T; peripheral-blood; endometrial; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4; ENST00000616356.4
External Link RMBase: m6A_site_846164
mod ID: M6ASITE090416 Click to Show/Hide the Full List
mod site chr9:134913124-134913125:- [3]
Sequence AGGCCCACGCAACTGCAAGGACCTGCTAGACCGGGGGTATT
Motif Score 3.622404762
Cell/Tissue List CD4T; peripheral-blood; endometrial; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4; ENST00000616356.4
External Link RMBase: m6A_site_846165
mod ID: M6ASITE090417 Click to Show/Hide the Full List
mod site chr9:134914416-134914417:- [3]
Sequence CCTGCCTCTTCCTCCAGGAGACCGAGGAGAGAAGGGGATGC
Motif Score 2.876744048
Cell/Tissue List CD4T; peripheral-blood; endometrial; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000616356.4; ENST00000371806.4
External Link RMBase: m6A_site_846166
mod ID: M6ASITE090418 Click to Show/Hide the Full List
mod site chr9:134914771-134914772:- [3]
Sequence GGAGCCCCTGGAAAGGCAGGACCAGTGGGGCCCAAAGGTAA
Motif Score 3.622404762
Cell/Tissue List CD4T; peripheral-blood; endometrial; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4; ENST00000616356.4
External Link RMBase: m6A_site_846167
mod ID: M6ASITE090419 Click to Show/Hide the Full List
mod site chr9:134917779-134917780:- [4]
Sequence CCTGCCTGCCCAGGCTGCGGACACATGTCCAGGTGAGACAG
Motif Score 3.643047619
Cell/Tissue List CD34; CD4T; peripheral-blood; endometrial; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4; ENST00000616356.4
External Link RMBase: m6A_site_846168
mod ID: M6ASITE090420 Click to Show/Hide the Full List
mod site chr9:134917800-134917801:- [4]
Sequence CTTGTTCCTGCATATCAAGAACCTGCCTGCCCAGGCTGCGG
Motif Score 2.930744048
Cell/Tissue List CD34; CD4T; peripheral-blood; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000616356.4; ENST00000371806.4
External Link RMBase: m6A_site_846169
mod ID: M6ASITE090421 Click to Show/Hide the Full List
mod site chr9:134917897-134917898:- [3]
Sequence TGCCCTGTTAGAGCTGGGGGACTCTTCAGAGTCAAAGGCCA
Motif Score 4.065041667
Cell/Tissue List CD4T; peripheral-blood
Seq Type List m6A-seq
Transcript ID List ENST00000371806.4
External Link RMBase: m6A_site_846170