Epigenetic Target Information

General Information of the Epigenetic Target (ID: EPITAR00509)
Target Name High affinity immunoglobulin gamma Fc receptor I (FCGR1A)
Synonyms
IgG Fc receptor I; Fc-gamma RI; FcRI; Fc-gamma RIA; FcgammaRIa; CD antigen CD64; FCG1; FCGR1; IGFR1
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Gene Name FCGR1A
Sequence
MWFLTTLLLWVPVDGQVDTTKAVITLQPPWVSVFQEETVTLHCEVLHLPGSSSTQWFLNGTATQTSTPSYRITSASVNDSGEYRCQRGLSGRSDPIQLEIHRGWLLLQVSSRVFTEGEPLALRCHAWKDKLVYNVLYYRNGKAFKFFHWNSNLTILKTNISHNGTYHCSGMGKHRYTSAGISVTVKELFPAPVLNASVTSPLLEGNLVTLSCETKLLLQRPGLQLYFSFYMGSKTLRGRNTSSEYQILTARREDSGLYWCEAATEDGNVLKRSPELELQVLGLQLPTPVWFHVLFYLAVGIMFLVNTVLWVTIRKELKRKKKWDLEISLDSGHEKKVISSLQEDRHLEEELKCQEQKEEQLQEGVHRKEPQGAT
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Family Immunoglobulin superfamily. FCGR1 family. {ECO:0000305}.
Function
High affinity receptor for the Fc region of immunoglobulins gamma. Functions in both innate and adaptive immune responses. Mediates IgG effector functions on monocytes triggering antibody-dependent cellular cytotoxicity (ADCC) of virus-infected cells. {ECO:0000269|PubMed:10397749, ECO:0000269|PubMed:10514529, ECO:0000269|PubMed:11711607, ECO:0000269|PubMed:21965667, ECO:0000269|PubMed:8611682, ECO:0000269|PubMed:9881690}.
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Gene ID 2209
HGNC ID HGNC:3613
Ensembl Gene ID ENSG00000150337
KEGG ID hsa:2209
Chromosomal Location 1q21.2
RNA Modification Sequencing Data Associated with the Target (ID: EPITAR00509)
High affinity immunoglobulin gamma Fc receptor I (FCGR1A)
N6-methyladenosine (m6A)
In total 8 m6A sequence/site(s) in this target gene
mod ID: M6ASITE049745 Click to Show/Hide the Full List
mod site chr1:149791308-149791309:+ [1]
Sequence GGGAATAATGTTTTTAGTGAACACTGTTCTCTGGGTGACAA
Motif Score 2.951386905
Cell/Tissue List MM6
Seq Type List m6A-seq
Transcript ID List ENST00000489704.1; ENST00000444948.5; ENST00000369168.4
External Link RMBase: m6A_site_50810
mod ID: M6ASITE049746 Click to Show/Hide the Full List
mod site chr1:149791339-149791340:+ [1]
Sequence TGGGTGACAATACGTAAAGAACTGAAAAGAAAGAAAAAGTG
Motif Score 3.373380952
Cell/Tissue List MM6
Seq Type List m6A-seq
Transcript ID List ENST00000444948.5; ENST00000369168.4; ENST00000489704.1
External Link RMBase: m6A_site_50811
mod ID: M6ASITE049747 Click to Show/Hide the Full List
mod site chr1:149791422-149791423:+ [1]
Sequence AATTTCCAGCCTTCAAGAAGACAGACATTTAGAAGAAGAGC
Motif Score 2.897386905
Cell/Tissue List MM6
Seq Type List m6A-seq
Transcript ID List ENST00000369168.4; ENST00000489704.1
External Link RMBase: m6A_site_50812
mod ID: M6ASITE049748 Click to Show/Hide the Full List
mod site chr1:149791456-149791457:+ [1]
Sequence GAAGAGCTGAAATGTCAGGAACAAAAAGAAGAACAGCTGCA
Motif Score 2.951386905
Cell/Tissue List MM6
Seq Type List m6A-seq
Transcript ID List ENST00000489704.1; ENST00000369168.4
External Link RMBase: m6A_site_50813
mod ID: M6ASITE049749 Click to Show/Hide the Full List
mod site chr1:149791547-149791548:+ [1]
Sequence GTGGGTGGCCATCGATCTGGACCGTCCCCTGCCCACTTGCT
Motif Score 3.622404762
Cell/Tissue List MM6; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000369168.4; ENST00000489704.1
External Link RMBase: m6A_site_50814
mod ID: M6ASITE049750 Click to Show/Hide the Full List
mod site chr1:149791589-149791590:+ [1]
Sequence CCCGTGAGCACTGCGTACAAACATCCAAAAGTTCAACAACA
Motif Score 2.20572619
Cell/Tissue List MM6; peripheral-blood; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000489704.1; ENST00000369168.4
External Link RMBase: m6A_site_50815
mod ID: M6ASITE049751 Click to Show/Hide the Full List
mod site chr1:149791615-149791616:+ [1]
Sequence AAAAGTTCAACAACACCAGAACTGTGTGTCTCATGGTATGT
Motif Score 3.373380952
Cell/Tissue List MM6; peripheral-blood; NB4; AML
Seq Type List m6A-seq; miCLIP
Transcript ID List ENST00000369168.4; ENST00000489704.1
External Link RMBase: m6A_site_50816
mod ID: M6ASITE049752 Click to Show/Hide the Full List
mod site chr1:149791658-149791659:+ [1]
Sequence CTCTTAAAGCAAATAAATGAACTGACTTCAACTGGGATACA
Motif Score 3.373380952
Cell/Tissue List MM6; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000489704.1; ENST00000369168.4
External Link RMBase: m6A_site_50817