Epigenetic Target Information

General Information of the Epigenetic Target (ID: EPITAR00492)
Target Name Anaphase promoting complex subunit 10 (ANAPC10)
Synonyms
APC10; DOC1; DKFZP564L0562
    Click to Show/Hide
Gene Name ANAPC10
Sequence
MTTPNKTPPGADPKQLERTGTVREIGSQAVWSLSSCKPGFGVDQLRDDNLETYWQSDGSQPHLVNIQFRRKTTVKTLCIYADYKSDESYTPSKISVRVGNNFHNLQEIRQLELVEPSGWIHVPLTDNHKKPTRTFMIQIAVLANHQNGRDTHMRQIKIYTPVEESSIGKFPRCTTIDFMMYRSIR
    Click to Show/Hide
Family APC10 family
Function
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
    Click to Show/Hide
Gene ID 10393
HGNC ID HGNC:24077
Ensembl Gene ID ENSG00000164162
KEGG ID hsa:10393
Chromosomal Location 4q31.21
RNA Modification Sequencing Data Associated with the Target (ID: EPITAR00492)
Anaphase promoting complex subunit 10 (ANAPC10)
N4-acetylcytidine (ac4C)
In total 1 m6A sequence/site(s) in this target gene
mod ID: AC4SITE000089 Click to Show/Hide the Full List
mod site chr4:145098419-145098420:-
Sequence CTCTCCGGGCTATTCACGTACCTGGAGAAAACGATCCCCTT
Cell/Tissue List DLD1
Seq Type List acRIP-seq
Transcript ID List ENST00000514390.5; ENST00000613466.4
External Link RMBase: ac4C_site_1467
Adenosine-to-Inosine editing (A-to-I)
In total 7 m6A sequence/site(s) in this target gene
mod ID: A2ISITE000588 Click to Show/Hide the Full List
mod site chr4:144983115-144983116:- [1]
Sequence CCAGGCTGGAGTGTAGTGGCACGATCTTGGCTCACTGCAGC
Transcript ID List ENST00000506851.5; ENST00000641499.1; ENST00000649263.1
External Link RMBase: RNA-editing_site_106774
mod ID: A2ISITE000589 Click to Show/Hide the Full List
mod site chr4:145005537-145005538:- [1]
Sequence ACAACCTACGATCATAACTAAAAGAACTAGGGAACCGAGAG
Transcript ID List ENST00000641499.1; ENST00000514390.5; ENST00000510270.5; ENST00000513054.5; ENST00000649263.1; ENST00000613466.4; ENST00000506851.5; ENST00000451299.6; ENST00000507656.6; ENST00000511466.5; ENST00000309439.9; ENST00000502651.5; rmsk_1463009
External Link RMBase: RNA-editing_site_106775
mod ID: A2ISITE000590 Click to Show/Hide the Full List
mod site chr4:145005963-145005964:- [1]
Sequence CACTTAACTAAATGGGCCTAATAGATATCTACAGAACTCTC
Transcript ID List ENST00000510270.5; ENST00000613466.4; ENST00000641499.1; ENST00000511466.5; ENST00000514390.5; rmsk_1463009; ENST00000309439.9; ENST00000649263.1; ENST00000502651.5; ENST00000513054.5; ENST00000507656.6; ENST00000451299.6; ENST00000506851.5
External Link RMBase: RNA-editing_site_106776
mod ID: A2ISITE000591 Click to Show/Hide the Full List
mod site chr4:145005964-145005965:- [1]
Sequence ACACTTAACTAAATGGGCCTAATAGATATCTACAGAACTCT
Transcript ID List ENST00000613466.4; ENST00000641499.1; ENST00000511466.5; ENST00000502651.5; ENST00000451299.6; ENST00000507656.6; ENST00000514390.5; ENST00000513054.5; ENST00000309439.9; ENST00000649263.1; ENST00000510270.5; rmsk_1463009; ENST00000506851.5
External Link RMBase: RNA-editing_site_106777
mod ID: A2ISITE000592 Click to Show/Hide the Full List
mod site chr4:145006052-145006053:- [1]
Sequence AATAATAGTGGGGAGACTTTAACACCACACTGTTAGTATTA
Transcript ID List rmsk_1463009; ENST00000510270.5; ENST00000649263.1; ENST00000513054.5; ENST00000514390.5; ENST00000507656.6; ENST00000506851.5; ENST00000309439.9; ENST00000641499.1; ENST00000613466.4; ENST00000451299.6; ENST00000502651.5; ENST00000511466.5
External Link RMBase: RNA-editing_site_106778
mod ID: A2ISITE000593 Click to Show/Hide the Full List
mod site chr4:145039710-145039711:- [1]
Sequence TCCTAGCTACTCAGGAGGCTAAGGCAGGAGAATTGCTTGAA
Transcript ID List ENST00000510270.5; ENST00000649263.1; ENST00000613466.4; ENST00000641499.1; ENST00000309439.9; ENST00000502562.5; ENST00000506851.5; ENST00000507656.6; ENST00000511466.5; rmsk_1463065; ENST00000513054.5; ENST00000502651.5; ENST00000451299.6; ENST00000514390.5
External Link RMBase: RNA-editing_site_106779
mod ID: A2ISITE000595 Click to Show/Hide the Full List
mod site chr4:145097042-145097043:- [1]
Sequence TGATTTTTTGGAATTTTTTTAGAGACAGGGTTTCACCATAT
Transcript ID List ENST00000510270.5; ENST00000507656.6; ENST00000514390.5; ENST00000502651.5; ENST00000309439.9; ENST00000502562.5; ENST00000451299.6; ENST00000514704.5; ENST00000649263.1; ENST00000512680.5; ENST00000502847.1; ENST00000507134.5; ENST00000613466.4; ENST00000511466.5; ENST00000506851.5; ENST00000504721.5; ENST00000508087.5; ENST00000513054.5; ENST00000641499.1
External Link RMBase: RNA-editing_site_106780
N6-methyladenosine (m6A)
In total 16 m6A sequence/site(s) in this target gene
mod ID: M6ASITE068267 Click to Show/Hide the Full List
mod site chr4:144995194-144995195:- [2]
Sequence TATTATCTTTATTTTCTTTAACATGTAATAAAGCTCACATA
Motif Score 2.168095238
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000641499.1; ENST00000507656.6; ENST00000309439.9; ENST00000451299.6; ENST00000506851.5; ENST00000613466.4; ENST00000649263.1; ENST00000502651.5; ENST00000510270.5
External Link RMBase: m6A_site_652831
mod ID: M6ASITE068268 Click to Show/Hide the Full List
mod site chr4:144995233-144995234:- [2]
Sequence AATATTTTATTGTAACTTTGACAAATAAATTTGGGGTCATA
Motif Score 2.859755952
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000649263.1; ENST00000309439.9; ENST00000510270.5; ENST00000613466.4; ENST00000506851.5; ENST00000641499.1; ENST00000507656.6; ENST00000511466.5; ENST00000502651.5; ENST00000451299.6
External Link RMBase: m6A_site_652832
mod ID: M6ASITE068269 Click to Show/Hide the Full List
mod site chr4:144995239-144995240:- [2]
Sequence TTTAAAAATATTTTATTGTAACTTTGACAAATAAATTTGGG
Motif Score 2.590089286
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000506851.5; ENST00000502651.5; ENST00000613466.4; ENST00000649263.1; ENST00000507656.6; ENST00000510270.5; ENST00000511466.5; ENST00000309439.9; ENST00000641499.1; ENST00000451299.6
External Link RMBase: m6A_site_652833
mod ID: M6ASITE068270 Click to Show/Hide the Full List
mod site chr4:144995303-144995304:- [2]
Sequence ATTTAAATAATATATCATGTACCTTTATTGAACAAGGCATC
Motif Score 2.8355
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000613466.4; ENST00000641499.1; ENST00000510270.5; ENST00000502651.5; ENST00000309439.9; ENST00000649263.1; ENST00000451299.6; ENST00000507656.6; ENST00000506851.5; ENST00000511466.5
External Link RMBase: m6A_site_652834
mod ID: M6ASITE068271 Click to Show/Hide the Full List
mod site chr4:144995359-144995360:- [2]
Sequence TAAGGTGACTTTAAAATGAGACGAAAATCATTAAACGTATC
Motif Score 2.871321429
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000510270.5; ENST00000507656.6; ENST00000506851.5; ENST00000502651.5; ENST00000649263.1; ENST00000451299.6; ENST00000511466.5; ENST00000613466.4; ENST00000641499.1; ENST00000309439.9
External Link RMBase: m6A_site_652835
mod ID: M6ASITE068272 Click to Show/Hide the Full List
mod site chr4:144995372-144995373:- [2]
Sequence ATGTATCGTTCAATAAGGTGACTTTAAAATGAGACGAAAAT
Motif Score 3.28175
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000451299.6; ENST00000511466.5; ENST00000507656.6; ENST00000641499.1; ENST00000510270.5; ENST00000506851.5; ENST00000613466.4; ENST00000502651.5; ENST00000649263.1; ENST00000309439.9
External Link RMBase: m6A_site_652836
mod ID: M6ASITE068273 Click to Show/Hide the Full List
mod site chr4:144995407-144995408:- [2]
Sequence GTAAATTTCCTAGATGTACAACTATAGATTTCATGATGTAT
Motif Score 2.595904762
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000511466.5; ENST00000506851.5; ENST00000451299.6; ENST00000613466.4; ENST00000510270.5; ENST00000502651.5; ENST00000641499.1; ENST00000507656.6; ENST00000309439.9; ENST00000649263.1
External Link RMBase: m6A_site_652837
mod ID: M6ASITE068274 Click to Show/Hide the Full List
mod site chr4:144995410-144995411:- [2]
Sequence TTGGTAAATTTCCTAGATGTACAACTATAGATTTCATGATG
Motif Score 2.856142857
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000641499.1; ENST00000649263.1; ENST00000502651.5; ENST00000510270.5; ENST00000613466.4; ENST00000506851.5; ENST00000511466.5; ENST00000451299.6; ENST00000507656.6; ENST00000309439.9
External Link RMBase: m6A_site_652838
mod ID: M6ASITE068275 Click to Show/Hide the Full List
mod site chr4:144995468-144995469:- [3]
Sequence GGAAGAGACACCCATATGAGACAAATTAAAATATACACACC
Motif Score 2.897386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000513054.5; ENST00000641499.1; ENST00000309439.9; ENST00000510270.5; ENST00000506851.5; ENST00000451299.6; ENST00000649263.1; ENST00000511466.5; ENST00000613466.4; ENST00000514390.5; ENST00000507656.6; ENST00000502651.5
External Link RMBase: m6A_site_652839
mod ID: M6ASITE068276 Click to Show/Hide the Full List
mod site chr4:144995481-144995482:- [3]
Sequence CAATCACCAGAATGGAAGAGACACCCATATGAGACAAATTA
Motif Score 2.897386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000510270.5; ENST00000451299.6; ENST00000513054.5; ENST00000641499.1; ENST00000613466.4; ENST00000502651.5; ENST00000506851.5; ENST00000507656.6; ENST00000649263.1; ENST00000514390.5; ENST00000511466.5; ENST00000309439.9
External Link RMBase: m6A_site_652840
mod ID: M6ASITE068277 Click to Show/Hide the Full List
mod site chr4:145033153-145033154:- [4]
Sequence CATACACAGCCTTCTGGAGAACTTTGCCCCAGTCCTGCAAA
Motif Score 3.373380952
Cell/Tissue List HepG2; HeLa; A549; HEK293T; H1B; GM12878; Huh7; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000451299.6; ENST00000613466.4; ENST00000513054.5; ENST00000510270.5; ENST00000511466.5; ENST00000507656.6; ENST00000502651.5; ENST00000514390.5; ENST00000641499.1; ENST00000502562.5; ENST00000506851.5; ENST00000649263.1; ENST00000309439.9
External Link RMBase: m6A_site_652841
mod ID: M6ASITE068278 Click to Show/Hide the Full List
mod site chr4:145033187-145033188:- [3]
Sequence GAAACTGTACCATATATTGGACCCTGATTCAGAGCATACAC
Motif Score 3.622404762
Cell/Tissue List HeLa; HepG2; HEK293T; A549; H1A; H1B; GM12878; Huh7; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000502562.5; ENST00000513054.5; ENST00000511466.5; ENST00000506851.5; ENST00000641499.1; ENST00000451299.6; ENST00000502651.5; ENST00000649263.1; ENST00000514390.5; ENST00000510270.5; ENST00000507656.6; ENST00000613466.4; ENST00000309439.9
External Link RMBase: m6A_site_652842
mod ID: M6ASITE068279 Click to Show/Hide the Full List
mod site chr4:145033204-145033205:- [3]
Sequence GAATCCTGGCTATGGGAGAAACTGTACCATATATTGGACCC
Motif Score 2.627720238
Cell/Tissue List HeLa; HepG2; HEK293T; A549; H1A; H1B; GM12878; Huh7; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000641499.1; ENST00000309439.9; ENST00000511466.5; ENST00000451299.6; ENST00000514390.5; ENST00000513054.5; ENST00000649263.1; ENST00000507656.6; ENST00000502651.5; ENST00000510270.5; ENST00000502562.5; ENST00000506851.5; ENST00000613466.4
External Link RMBase: m6A_site_652843
mod ID: M6ASITE068280 Click to Show/Hide the Full List
mod site chr4:145033229-145033230:- [3]
Sequence TCCACCCCTTGATTCCTGGAACTGTGAATCCTGGCTATGGG
Motif Score 3.373380952
Cell/Tissue List HeLa; HepG2; HEK293T; A549; H1B; GM12878; Huh7; HEK293A-TOA; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000641499.1; ENST00000502562.5; ENST00000510270.5; ENST00000502651.5; ENST00000507656.6; ENST00000513054.5; ENST00000514390.5; ENST00000506851.5; ENST00000451299.6; ENST00000649263.1; ENST00000511466.5; ENST00000309439.9; ENST00000613466.4
External Link RMBase: m6A_site_652844
mod ID: M6ASITE068281 Click to Show/Hide the Full List
mod site chr4:145033308-145033309:- [3]
Sequence CAGAACGTAATGTCGTGGGAACAGGAAGCAAAAATGTTGCC
Motif Score 2.951386905
Cell/Tissue List HeLa; HEK293T; Huh7; HEK293A-TOA
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000507656.6; ENST00000513054.5; ENST00000511466.5; ENST00000649263.1; ENST00000613466.4; ENST00000309439.9; ENST00000514390.5; ENST00000451299.6; ENST00000510270.5; ENST00000506851.5; ENST00000502562.5; ENST00000502651.5; ENST00000641499.1
External Link RMBase: m6A_site_652845
mod ID: M6ASITE068282 Click to Show/Hide the Full List
mod site chr4:145098441-145098442:- [5]
Sequence AGATGGCAGCTAACGGCCAAACCTCTCCGGGCTATTCACGT
Motif Score 2.185083333
Cell/Tissue List MSC; NB4
Seq Type List MeRIP-seq; m6A-seq
Transcript ID List ENST00000613466.4; ENST00000514390.5
External Link RMBase: m6A_site_652847