Epigenetic Target Information

General Information of the Epigenetic Target (ID: EPITAR00489)

Target Name	Long intergenic non-protein coding RNA 1605 (LINC01605)
Synonyms	ODIR1; lncGALM; LincDUSP; RP11-527N22.2; TCONS_00014973 Click to Show/Hide
Gene Name	LINC01605
Family	Long intergenic non-protein coding RNAs
Gene ID	100507420
HGNC ID	HGNC:51654
Ensembl Gene ID	ENSG00000253161
Chromosomal Location	8p11.23

RNA Modification Sequencing Data Associated with the Target (ID: EPITAR00489)

Long intergenic non-protein coding RNA 1605 (LINC01605)

N6-methyladenosine (m6A)

In total 10 m6A sequence/site(s) in this target gene
mod ID: M6ASITE084552		Click to Show/Hide the Full List
mod site	chr8:37421524-37421525:-		[1]
Sequence	CCAGCAGGACCAGAGAGAAGACCACAGCGACACATGGGGAT
Motif Score	2.876744048
Cell/Tissue List	MT4; HEK293T
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000520422.5; ENST00000522718.5
External Link	RMBase: m6A_site_793308
mod ID: M6ASITE084553		Click to Show/Hide the Full List
mod site	chr8:37421536-37421537:-		[1]
Sequence	TGGTCCAGGAGGCCAGCAGGACCAGAGAGAAGACCACAGCG
Motif Score	3.622404762
Cell/Tissue List	MT4; HEK293T
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000520422.5; ENST00000522718.5
External Link	RMBase: m6A_site_793309
mod ID: M6ASITE084554		Click to Show/Hide the Full List
mod site	chr8:37475978-37475979:-		[2]
Sequence	TCAACTCATTCCCGTTACAAACAGCCGACCTTCCTACCGAG
Motif Score	2.20572619
Cell/Tissue List	MSC
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000522718.5; ENST00000520422.5; ENST00000519738.5; ENST00000517363.1
External Link	RMBase: m6A_site_793310
mod ID: M6ASITE084555		Click to Show/Hide the Full List
mod site	chr8:37493505-37493506:-		[2]
Sequence	AGTCTGTGTGACAGAATGGGACCTGTGGGAAAGCAGCACGT
Motif Score	3.622404762
Cell/Tissue List	MSC; TIME
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000522718.5; ENST00000520422.5; ENST00000519738.5; ENST00000517363.1
External Link	RMBase: m6A_site_793311
mod ID: M6ASITE084556		Click to Show/Hide the Full List
mod site	chr8:37493627-37493628:-		[3]
Sequence	TTAACCTCCATGAGGCTTGGACTTTCAGGCTTCCTCCCTCA
Motif Score	4.065041667
Cell/Tissue List	GSC-11; iSLK; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000519738.5; ENST00000520422.5; ENST00000517363.1; ENST00000522718.5
External Link	RMBase: m6A_site_793312
mod ID: M6ASITE084557		Click to Show/Hide the Full List
mod site	chr8:37493650-37493651:-		[4]
Sequence	TTGGACTTGGTCTACATTAGACTTTAACCTCCATGAGGCTT
Motif Score	3.319380952
Cell/Tissue List	fibroblasts; GSC-11; iSLK; MSC; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000522718.5; ENST00000517363.1; ENST00000519738.5; ENST00000520422.5
External Link	RMBase: m6A_site_793313
mod ID: M6ASITE084558		Click to Show/Hide the Full List
mod site	chr8:37493666-37493667:-		[4]
Sequence	AGGCTCTCCATCGAACTTGGACTTGGTCTACATTAGACTTT
Motif Score	4.065041667
Cell/Tissue List	fibroblasts; GSC-11; iSLK; MSC; TIME; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000517363.1; ENST00000520422.5; ENST00000522718.5; ENST00000519738.5
External Link	RMBase: m6A_site_793314
mod ID: M6ASITE084559		Click to Show/Hide the Full List
mod site	chr8:37493672-37493673:-		[4]
Sequence	AGTCTAAGGCTCTCCATCGAACTTGGACTTGGTCTACATTA
Motif Score	3.373380952
Cell/Tissue List	fibroblasts; GSC-11; iSLK; MSC; TIME; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000517363.1; ENST00000520422.5; ENST00000519738.5; ENST00000522718.5
External Link	RMBase: m6A_site_793315
mod ID: M6ASITE084560		Click to Show/Hide the Full List
mod site	chr8:37493741-37493742:-		[1]
Sequence	GAGAAGGCTGGAGAGAGGGAACATGGGTCTGAGGGCACATC
Motif Score	2.951386905
Cell/Tissue List	MT4; GSC-11; MSC; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000520422.5; ENST00000522718.5; ENST00000517363.1; ENST00000519738.5
External Link	RMBase: m6A_site_793316
mod ID: M6ASITE084561		Click to Show/Hide the Full List
mod site	chr8:37516821-37516822:-		[5]
Sequence	GGGCTTAGATGACAGCTTGAACTCTGCGGCTGATGGAATTG
Motif Score	3.373380952
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000519738.5; ENST00000517363.1; ENST00000521989.2
External Link	RMBase: m6A_site_793317

Pseudouridine (Pseudo)

In total 1 m6A sequence/site(s) in this target gene
mod ID: PSESITE000259		Click to Show/Hide the Full List
mod site	chr8:37475885-37475886:-		[6]
Sequence	TCCACTGGCCCTCACCTGCCTTCCCCTGAACATGCATTTTG
Transcript ID List	ENST00000520422.5; ENST00000519738.5; ENST00000522718.5
External Link	RMBase: Pseudo_site_4563

Ref 1	Dynamics of the human and viral m(6)A RNA methylomes during HIV-1 infection of T cells. Nat Microbiol. 2016 Feb 22;1:16011. doi: 10.1038/nmicrobiol.2016.11.
Ref 2	Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018 Jan;3(1):108-120. doi: 10.1038/s41564-017-0056-8. Epub 2017 Nov 6.
Ref 3	m(6)A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program. Cancer Cell. 2017 Apr 10;31(4):591-606.e6. doi: 10.1016/j.ccell.2017.02.013. Epub 2017 Mar 23.
Ref 4	Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. Cell Rep. 2014 Jul 10;8(1):284-96. doi: 10.1016/j.celrep.2014.05.048. Epub 2014 Jun 26.
Ref 5	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 6	Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome. Nat Chem Biol. 2015 Aug;11(8):592-7. doi: 10.1038/nchembio.1836. Epub 2015 Jun 15.

Epigenetic Target Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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