Epigenetic Target Information

General Information of the Epigenetic Target (ID: EPITAR00445)
Target Name Toll-like receptor 4 (TLR4)
Synonyms
hToll; CD antigen CD284
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Gene Name TLR4
Sequence
MMSASRLAGTLIPAMAFLSCVRPESWEPCVEVVPNITYQCMELNFYKIPDNLPFSTKNLDLSFNPLRHLGSYSFFSFPELQVLDLSRCEIQTIEDGAYQSLSHLSTLILTGNPIQSLALGAFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEHLDLSSNKIQSIYCTDLRVLHQMPLLNLSLDLSLNPMNFIQPGAFKEIRLHKLTLRNNFDSLNVMKTCIQGLAGLEVHRLVLGEFRNEGNLEKFDKSALEGLCNLTIEEFRLAYLDYYLDDIIDLFNCLTNVSSFSLVSVTIERVKDFSYNFGWQHLELVNCKFGQFPTLKLKSLKRLTFTSNKGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTTSLKYLDLSFNGVITMSSNFLGLEQLEHLDFQHSNLKQMSEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLSSLEVLKMAGNSFQENFLPDIFTELRNLTFLDLSQCQLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPYKCLNSLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDFACTCEHQSFLQWIKDQRQLLVEVERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVLSVLVVSVVAVLVYKFYFHLMLLAGCIKYGRGENIYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAANIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLRQQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKSWNPEGTVGTGCNWQEATSI
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Family Toll-like receptor family
Function
Transmembrane receptor that functions as a pattern recognition receptor recognizing pathogen- and damage-associated molecular patterns (PAMPs and DAMPs) to induce innate immune responses via downstream signaling pathways (PubMed:16622205, PubMed:10835634, PubMed:15809303, PubMed:17478729, PubMed:20037584, PubMed:20711192, PubMed:23880187, PubMed:27022195, PubMed:17292937, PubMed:29038465). At the plasma membrane, cooperates with LY96 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) (PubMed:27022195). Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni(2+) (PubMed:20711192). Mechanistically, acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:9237759, PubMed:10835634, PubMed:27022195, PubMed:21393102). Alternatively, CD14-mediated TLR4 internalization via endocytosis is associated with the initiation of a MYD88-independent signaling via the TICAM1-TBK1-IRF3 axis leading to type I interferon production (PubMed:14517278). In addition to the secretion of proinflammatory cytokines, initiates the activation of NLRP3 inflammasome and formation of a positive feedback loop between autophagy and NF-kappa-B signaling cascade (PubMed:32894580). In complex with TLR6, promotes inflammation in monocytes/macrophages by associating with TLR6 and the receptor CD86 (PubMed:23880187). Upon ligand binding, such as oxLDL or amyloid-beta 42, the TLR4:TLR6 complex is internalized and triggers inflammatory response, leading to NF-kappa-B-dependent production of CXCL1, CXCL2 and CCL9 cytokines, via MYD88 signaling pathway, and CCL5 cytokine, via TICAM1 signaling pathway (PubMed:23880187). In myeloid dendritic cells, vesicular stomatitis virus glycoprotein G but not LPS promotes the activation of IRF7, leading to type I IFN production in a CD14-dependent manner (PubMed:23880187, PubMed:15265881). Required for the migration-promoting effects of ZG16B/PAUF on pancreatic cancer cells.
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Gene ID 7099
HGNC ID HGNC:11850
Ensembl Gene ID ENSG00000136869
KEGG ID hsa:7099
Chromosomal Location 9q33.1
RNA Modification Sequencing Data Associated with the Target (ID: EPITAR00445)
Toll-like receptor 4 (TLR4)
5-methylcytidine (m5C)
In total 1 m6A sequence/site(s) in this target gene
mod ID: M5CSITE004435 Click to Show/Hide the Full List
mod site chr9:117714249-117714250:+
Sequence CTCCATTTCAGCTCTGCCTTCACTACAGAGACTTTATTCCC
Cell/Tissue List T24
Seq Type List Bisulfite-seq
Transcript ID List ENST00000394487.5; ENST00000645071.1; ENST00000642985.1; ENST00000646089.1; ENST00000472304.2; ENST00000355622.8
External Link RMBase: m5C_site_43348
N6-methyladenosine (m6A)
In total 67 m6A sequence/site(s) in this target gene
mod ID: M6ASITE089397 Click to Show/Hide the Full List
mod site chr9:117704268-117704269:+ [1]
Sequence AAGAGATAACTATTAGAGAAACAAAAGTCCAGAATGCTAAG
Motif Score 2.20572619
Cell/Tissue List MSC
Seq Type List MeRIP-seq
Transcript ID List ENST00000642985.1; ENST00000645071.1; ENST00000472304.2; ENST00000394487.5
External Link RMBase: m6A_site_835719
mod ID: M6ASITE089399 Click to Show/Hide the Full List
mod site chr9:117704326-117704327:+ [1]
Sequence CTCTCACCCTTTAGCCCAGAACTGCTTTGAATACACCAATT
Motif Score 3.373380952
Cell/Tissue List MSC; TIME
Seq Type List MeRIP-seq
Transcript ID List ENST00000394487.5; ENST00000645071.1; ENST00000472304.2; ENST00000642985.1
External Link RMBase: m6A_site_835720
mod ID: M6ASITE089400 Click to Show/Hide the Full List
mod site chr9:117704374-117704375:+ [2]
Sequence GGCGGCTCGAGGAAGAGAAGACACCAGTGCCTCAGAAACTG
Motif Score 2.897386905
Cell/Tissue List peripheral-blood; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000645071.1; ENST00000642985.1; ENST00000394487.5; ENST00000472304.2
External Link RMBase: m6A_site_835721
mod ID: M6ASITE089401 Click to Show/Hide the Full List
mod site chr9:117704391-117704392:+ [2]
Sequence AAGACACCAGTGCCTCAGAAACTGCTCGGTCAGACGGTGAT
Motif Score 2.627720238
Cell/Tissue List peripheral-blood; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000472304.2; ENST00000642985.1; ENST00000646089.1; ENST00000394487.5; ENST00000645071.1
External Link RMBase: m6A_site_835722
mod ID: M6ASITE089402 Click to Show/Hide the Full List
mod site chr9:117704499-117704500:+ [3]
Sequence CTGCCTCGCGCCTGGCTGGGACTCTGATCCCAGCCATGGCC
Motif Score 4.065041667
Cell/Tissue List CD4T; peripheral-blood; endometrial; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000645071.1; ENST00000646089.1; ENST00000394487.5; ENST00000642985.1; ENST00000472304.2; ENST00000355622.8
External Link RMBase: m6A_site_835723
mod ID: M6ASITE089403 Click to Show/Hide the Full List
mod site chr9:117704537-117704538:+ [3]
Sequence GCCTTCCTCTCCTGCGTGAGACCAGAAAGCTGGGAGCCCTG
Motif Score 2.876744048
Cell/Tissue List CD4T; peripheral-blood; endometrial; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000642985.1; ENST00000472304.2; ENST00000394487.5; ENST00000646089.1; ENST00000355622.8; ENST00000645071.1
External Link RMBase: m6A_site_835724
mod ID: M6ASITE089404 Click to Show/Hide the Full List
mod site chr9:117708198-117708199:+ [3]
Sequence ATTTTGTTTTGTTTTTAAAGACTTGGCCCTAAACCACACAG
Motif Score 3.319380952
Cell/Tissue List CD4T; peripheral-blood; endometrial; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000490685.1; ENST00000642985.1; ENST00000646089.1; ENST00000394487.5; ENST00000645071.1; ENST00000472304.2; ENST00000355622.8
External Link RMBase: m6A_site_835725
mod ID: M6ASITE089405 Click to Show/Hide the Full List
mod site chr9:117708210-117708211:+ [3]
Sequence TTTTAAAGACTTGGCCCTAAACCACACAGAAGAGCTGGCAT
Motif Score 2.185083333
Cell/Tissue List CD4T; peripheral-blood; endometrial; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000472304.2; ENST00000645071.1; ENST00000490685.1; ENST00000394487.5; ENST00000355622.8; ENST00000642985.1; ENST00000646089.1
External Link RMBase: m6A_site_835726
mod ID: M6ASITE089406 Click to Show/Hide the Full List
mod site chr9:117708234-117708235:+ [2]
Sequence CACAGAAGAGCTGGCATGAAACCCAGAGCTTTCAGACTCCG
Motif Score 2.185083333
Cell/Tissue List peripheral-blood
Seq Type List m6A-seq
Transcript ID List ENST00000642985.1; ENST00000646089.1; ENST00000355622.8; ENST00000490685.1; ENST00000645071.1; ENST00000472304.2; ENST00000394487.5
External Link RMBase: m6A_site_835727
mod ID: M6ASITE089407 Click to Show/Hide the Full List
mod site chr9:117708249-117708250:+ [2]
Sequence ATGAAACCCAGAGCTTTCAGACTCCGGAGCCTCAGCCCTTC
Motif Score 3.319380952
Cell/Tissue List peripheral-blood
Seq Type List m6A-seq
Transcript ID List ENST00000394487.5; ENST00000642985.1; ENST00000355622.8; ENST00000490685.1; ENST00000472304.2; ENST00000646089.1; ENST00000645071.1
External Link RMBase: m6A_site_835728
mod ID: M6ASITE089408 Click to Show/Hide the Full List
mod site chr9:117708641-117708642:+ [2]
Sequence CCTCCCCTTCTCAACCAAGAACCTGGACCTGAGCTTTAATC
Motif Score 2.930744048
Cell/Tissue List peripheral-blood
Seq Type List m6A-seq
Transcript ID List ENST00000646089.1; ENST00000472304.2; ENST00000355622.8; ENST00000645071.1; ENST00000490685.1; ENST00000394487.5; ENST00000642985.1
External Link RMBase: m6A_site_835729
mod ID: M6ASITE089410 Click to Show/Hide the Full List
mod site chr9:117708647-117708648:+ [2]
Sequence CTTCTCAACCAAGAACCTGGACCTGAGCTTTAATCCCCTGA
Motif Score 3.622404762
Cell/Tissue List peripheral-blood
Seq Type List m6A-seq
Transcript ID List ENST00000472304.2; ENST00000394487.5; ENST00000646089.1; ENST00000355622.8; ENST00000490685.1; ENST00000645071.1; ENST00000642985.1
External Link RMBase: m6A_site_835730
mod ID: M6ASITE089411 Click to Show/Hide the Full List
mod site chr9:117712462-117712463:+ [4]
Sequence TACCTTAATATTGACAGGAAACCCCATCCAGAGTTTAGCCC
Motif Score 2.185083333
Cell/Tissue List HeLa; fibroblasts; A549; peripheral-blood; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000394487.5; ENST00000646089.1; ENST00000642985.1; ENST00000355622.8; ENST00000645071.1; ENST00000472304.2
External Link RMBase: m6A_site_835731
mod ID: M6ASITE089412 Click to Show/Hide the Full List
mod site chr9:117712499-117712500:+ [4]
Sequence GCCCTGGGAGCCTTTTCTGGACTATCAAGTTTACAGAAGCT
Motif Score 4.065041667
Cell/Tissue List HeLa; fibroblasts; A549; peripheral-blood; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000642985.1; ENST00000646089.1; ENST00000355622.8; ENST00000645071.1; ENST00000472304.2; ENST00000394487.5
External Link RMBase: m6A_site_835732
mod ID: M6ASITE089413 Click to Show/Hide the Full List
mod site chr9:117712533-117712534:+ [4]
Sequence AGAAGCTGGTGGCTGTGGAGACAAATCTAGCATCTCTAGAG
Motif Score 2.897386905
Cell/Tissue List HeLa; fibroblasts; A549; peripheral-blood; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000642985.1; ENST00000472304.2; ENST00000646089.1; ENST00000355622.8; ENST00000394487.5; ENST00000645071.1
External Link RMBase: m6A_site_835733
mod ID: M6ASITE089414 Click to Show/Hide the Full List
mod site chr9:117712555-117712556:+ [4]
Sequence AAATCTAGCATCTCTAGAGAACTTCCCCATTGGACATCTCA
Motif Score 3.373380952
Cell/Tissue List HeLa; HepG2; fibroblasts; A549; peripheral-blood; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000472304.2; ENST00000645071.1; ENST00000394487.5; ENST00000355622.8; ENST00000642985.1; ENST00000646089.1
External Link RMBase: m6A_site_835734
mod ID: M6ASITE089415 Click to Show/Hide the Full List
mod site chr9:117712568-117712569:+ [4]
Sequence CTAGAGAACTTCCCCATTGGACATCTCAAAACTTTGAAAGA
Motif Score 3.643047619
Cell/Tissue List HeLa; fibroblasts; A549; peripheral-blood; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000646089.1; ENST00000642985.1; ENST00000645071.1; ENST00000355622.8; ENST00000472304.2; ENST00000394487.5
External Link RMBase: m6A_site_835735
mod ID: M6ASITE089416 Click to Show/Hide the Full List
mod site chr9:117712578-117712579:+ [4]
Sequence TCCCCATTGGACATCTCAAAACTTTGAAAGAACTTAATGTG
Motif Score 2.627720238
Cell/Tissue List HeLa; fibroblasts; A549; GM12878; peripheral-blood; GSC-11; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000645071.1; ENST00000472304.2; ENST00000355622.8; ENST00000642985.1; ENST00000646089.1; ENST00000394487.5
External Link RMBase: m6A_site_835736
mod ID: M6ASITE089417 Click to Show/Hide the Full List
mod site chr9:117712589-117712590:+ [4]
Sequence CATCTCAAAACTTTGAAAGAACTTAATGTGGCTCACAATCT
Motif Score 3.373380952
Cell/Tissue List HeLa; fibroblasts; A549; GM12878; peripheral-blood; GSC-11; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000355622.8; ENST00000645071.1; ENST00000394487.5; ENST00000646089.1; ENST00000472304.2; ENST00000642985.1
External Link RMBase: m6A_site_835737
mod ID: M6ASITE089418 Click to Show/Hide the Full List
mod site chr9:117712669-117712670:+ [5]
Sequence GACCAATCTAGAGCACTTGGACCTTTCCAGCAACAAGATTC
Motif Score 3.622404762
Cell/Tissue List HeLa; U2OS; fibroblasts; A549; GM12878; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000645071.1; ENST00000646089.1; ENST00000355622.8; ENST00000394487.5; ENST00000472304.2; ENST00000642985.1
External Link RMBase: m6A_site_835738
mod ID: M6ASITE089419 Click to Show/Hide the Full List
mod site chr9:117712708-117712709:+ [5]
Sequence TCAAAGTATTTATTGCACAGACTTGCGGGTTCTACATCAAA
Motif Score 3.319380952
Cell/Tissue List HeLa; U2OS; fibroblasts; A549; GM12878; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000394487.5; ENST00000642985.1; ENST00000355622.8; ENST00000645071.1; ENST00000646089.1; ENST00000472304.2
External Link RMBase: m6A_site_835739
mod ID: M6ASITE089421 Click to Show/Hide the Full List
mod site chr9:117712753-117712754:+ [6]
Sequence CCTACTCAATCTCTCTTTAGACCTGTCCCTGAACCCTATGA
Motif Score 2.876744048
Cell/Tissue List fibroblasts; A549; GM12878; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000642985.1; ENST00000646089.1; ENST00000394487.5; ENST00000355622.8; ENST00000645071.1; ENST00000472304.2
External Link RMBase: m6A_site_835740
mod ID: M6ASITE089422 Click to Show/Hide the Full List
mod site chr9:117712765-117712766:+ [6]
Sequence CTCTTTAGACCTGTCCCTGAACCCTATGAACTTTATCCAAC
Motif Score 2.930744048
Cell/Tissue List fibroblasts; A549; GM12878; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000645071.1; ENST00000472304.2; ENST00000394487.5; ENST00000646089.1; ENST00000642985.1; ENST00000355622.8
External Link RMBase: m6A_site_835741
mod ID: M6ASITE089423 Click to Show/Hide the Full List
mod site chr9:117712774-117712775:+ [6]
Sequence CCTGTCCCTGAACCCTATGAACTTTATCCAACCAGGTGCAT
Motif Score 3.373380952
Cell/Tissue List fibroblasts; A549; GM12878; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000355622.8; ENST00000394487.5; ENST00000645071.1; ENST00000646089.1; ENST00000472304.2; ENST00000642985.1
External Link RMBase: m6A_site_835742
mod ID: M6ASITE089424 Click to Show/Hide the Full List
mod site chr9:117712860-117712861:+ [6]
Sequence ATAGTTTAAATGTAATGAAAACTTGTATTCAAGGTCTGGCT
Motif Score 2.627720238
Cell/Tissue List fibroblasts; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000646089.1; ENST00000645071.1; ENST00000355622.8; ENST00000642985.1; ENST00000394487.5; ENST00000472304.2
External Link RMBase: m6A_site_835743
mod ID: M6ASITE089425 Click to Show/Hide the Full List
mod site chr9:117712930-117712931:+ [7]
Sequence AGAATTTAGAAATGAAGGAAACTTGGAAAAGTTTGACAAAT
Motif Score 2.627720238
Cell/Tissue List U2OS; fibroblasts; MSC; TIME
Seq Type List MeRIP-seq; m6A-seq
Transcript ID List ENST00000355622.8; ENST00000642985.1; ENST00000394487.5; ENST00000645071.1; ENST00000646089.1; ENST00000472304.2
External Link RMBase: m6A_site_835744
mod ID: M6ASITE089426 Click to Show/Hide the Full List
mod site chr9:117713008-117713009:+ [7]
Sequence ATTCCGATTAGCATACTTAGACTACTACCTCGATGATATTA
Motif Score 3.319380952
Cell/Tissue List U2OS; fibroblasts; MSC; TIME
Seq Type List MeRIP-seq; m6A-seq
Transcript ID List ENST00000472304.2; ENST00000646089.1; ENST00000394487.5; ENST00000355622.8; ENST00000645071.1; ENST00000642985.1
External Link RMBase: m6A_site_835745
mod ID: M6ASITE089427 Click to Show/Hide the Full List
mod site chr9:117713101-117713102:+ [6]
Sequence GACTATTGAAAGGGTAAAAGACTTTTCTTATAATTTCGGAT
Motif Score 3.319380952
Cell/Tissue List fibroblasts; A549; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000472304.2; ENST00000645071.1; ENST00000394487.5; ENST00000646089.1; ENST00000355622.8; ENST00000642985.1
External Link RMBase: m6A_site_835746
mod ID: M6ASITE089428 Click to Show/Hide the Full List
mod site chr9:117713156-117713157:+ [6]
Sequence TTAGTTAACTGTAAATTTGGACAGTTTCCCACATTGAAACT
Motif Score 3.643047619
Cell/Tissue List fibroblasts; A549; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000472304.2; ENST00000642985.1; ENST00000394487.5; ENST00000355622.8; ENST00000646089.1; ENST00000645071.1
External Link RMBase: m6A_site_835747
mod ID: M6ASITE089429 Click to Show/Hide the Full List
mod site chr9:117713174-117713175:+ [6]
Sequence GGACAGTTTCCCACATTGAAACTCAAATCTCTCAAAAGGCT
Motif Score 2.627720238
Cell/Tissue List fibroblasts; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000472304.2; ENST00000642985.1; ENST00000394487.5; ENST00000646089.1; ENST00000645071.1; ENST00000355622.8
External Link RMBase: m6A_site_835748
mod ID: M6ASITE089430 Click to Show/Hide the Full List
mod site chr9:117713758-117713759:+ [6]
Sequence GTTTCCTTATAAGTGTCTGAACTCCCTCCAGGTTCTTGATT
Motif Score 3.373380952
Cell/Tissue List fibroblasts; GM12878; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000355622.8; ENST00000472304.2; ENST00000394487.5; ENST00000645071.1; ENST00000642985.1; ENST00000646089.1
External Link RMBase: m6A_site_835749
mod ID: M6ASITE089432 Click to Show/Hide the Full List
mod site chr9:117713810-117713811:+ [6]
Sequence CACATAATGACTTCCAAAAAACAGGAACTACAGCATTTTCC
Motif Score 2.20572619
Cell/Tissue List fibroblasts; GM12878; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000394487.5; ENST00000355622.8; ENST00000646089.1; ENST00000642985.1; ENST00000645071.1; ENST00000472304.2
External Link RMBase: m6A_site_835750
mod ID: M6ASITE089433 Click to Show/Hide the Full List
mod site chr9:117713816-117713817:+ [6]
Sequence ATGACTTCCAAAAAACAGGAACTACAGCATTTTCCAAGTAG
Motif Score 3.373380952
Cell/Tissue List fibroblasts; GM12878; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000645071.1; ENST00000394487.5; ENST00000472304.2; ENST00000355622.8; ENST00000646089.1; ENST00000642985.1
External Link RMBase: m6A_site_835751
mod ID: M6ASITE089434 Click to Show/Hide the Full List
mod site chr9:117713885-117713886:+ [4]
Sequence GACTTTGCTTGTACTTGTGAACACCAGAGTTTCCTGCAATG
Motif Score 2.951386905
Cell/Tissue List HeLa; fibroblasts; GM12878; peripheral-blood; iSLK; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000645071.1; ENST00000355622.8; ENST00000646089.1; ENST00000472304.2; ENST00000394487.5; ENST00000642985.1
External Link RMBase: m6A_site_835752
mod ID: M6ASITE089435 Click to Show/Hide the Full List
mod site chr9:117713914-117713915:+ [4]
Sequence TTTCCTGCAATGGATCAAGGACCAGAGGCAGCTCTTGGTGG
Motif Score 3.622404762
Cell/Tissue List HeLa; fibroblasts; GM12878; peripheral-blood; iSLK; MSC; TIME; TREX; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000646089.1; ENST00000472304.2; ENST00000642985.1; ENST00000394487.5; ENST00000645071.1; ENST00000355622.8
External Link RMBase: m6A_site_835753
mod ID: M6ASITE089436 Click to Show/Hide the Full List
mod site chr9:117714021-117714022:+ [4]
Sequence TCACCTGTCAGATGAATAAGACCATCATTGGTGTGTCGGTC
Motif Score 2.876744048
Cell/Tissue List HeLa; fibroblasts; peripheral-blood; MSC; TIME; TREX; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000355622.8; ENST00000646089.1; ENST00000394487.5; ENST00000642985.1; ENST00000472304.2; ENST00000645071.1
External Link RMBase: m6A_site_835754
mod ID: M6ASITE089437 Click to Show/Hide the Full List
mod site chr9:117714142-117714143:+ [6]
Sequence AAAGTATGGTAGAGGTGAAAACATCTATGATGCCTTTGTTA
Motif Score 2.20572619
Cell/Tissue List fibroblasts; peripheral-blood; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000646089.1; ENST00000645071.1; ENST00000355622.8; ENST00000472304.2; ENST00000394487.5; ENST00000642985.1
External Link RMBase: m6A_site_835755
mod ID: M6ASITE089438 Click to Show/Hide the Full List
mod site chr9:117714184-117714185:+ [6]
Sequence CTACTCAAGCCAGGATGAGGACTGGGTAAGGAATGAGCTAG
Motif Score 4.065041667
Cell/Tissue List fibroblasts; peripheral-blood; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000472304.2; ENST00000646089.1; ENST00000645071.1; ENST00000355622.8; ENST00000642985.1; ENST00000394487.5
External Link RMBase: m6A_site_835756
mod ID: M6ASITE089439 Click to Show/Hide the Full List
mod site chr9:117714259-117714260:+ [6]
Sequence GCTCTGCCTTCACTACAGAGACTTTATTCCCGGTGTGGCCA
Motif Score 3.319380952
Cell/Tissue List fibroblasts; A549; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000642985.1; ENST00000394487.5; ENST00000472304.2; ENST00000355622.8; ENST00000645071.1; ENST00000646089.1
External Link RMBase: m6A_site_835757
mod ID: M6ASITE089440 Click to Show/Hide the Full List
mod site chr9:117714393-117714394:+ [1]
Sequence TTGAATATGAGATTGCTCAGACCTGGCAGTTTCTGAGCAGT
Motif Score 2.876744048
Cell/Tissue List MSC; TIME
Seq Type List MeRIP-seq
Transcript ID List ENST00000394487.5; ENST00000646089.1; ENST00000472304.2; ENST00000645071.1; ENST00000642985.1; ENST00000355622.8
External Link RMBase: m6A_site_835758
mod ID: M6ASITE089441 Click to Show/Hide the Full List
mod site chr9:117714456-117714457:+ [4]
Sequence TCCTGCAGAAGGTGGAGAAGACCCTGCTCAGGCAGCAGGTG
Motif Score 2.876744048
Cell/Tissue List HeLa; peripheral-blood; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000394487.5; ENST00000472304.2; ENST00000646089.1; ENST00000642985.1; ENST00000645071.1; ENST00000355622.8
External Link RMBase: m6A_site_835759
mod ID: M6ASITE089443 Click to Show/Hide the Full List
mod site chr9:117714502-117714503:+ [4]
Sequence GTACCGCCTTCTCAGCAGGAACACTTACCTGGAGTGGGAGG
Motif Score 2.951386905
Cell/Tissue List HeLa; fibroblasts; peripheral-blood; MSC; TIME; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000472304.2; ENST00000642985.1; ENST00000394487.5; ENST00000646089.1; ENST00000645071.1; ENST00000355622.8
External Link RMBase: m6A_site_835760
mod ID: M6ASITE089444 Click to Show/Hide the Full List
mod site chr9:117714523-117714524:+ [4]
Sequence CACTTACCTGGAGTGGGAGGACAGTGTCCTGGGGCGGCACA
Motif Score 3.643047619
Cell/Tissue List HeLa; fibroblasts; MM6; CD4T; peripheral-blood; MSC; TIME; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000394487.5; ENST00000472304.2; ENST00000646089.1; ENST00000645071.1; ENST00000642985.1; ENST00000355622.8
External Link RMBase: m6A_site_835761
mod ID: M6ASITE089445 Click to Show/Hide the Full List
mod site chr9:117714603-117714604:+ [4]
Sequence AATCATGGAATCCAGAAGGAACAGTGGGTACAGGATGCAAT
Motif Score 2.951386905
Cell/Tissue List HeLa; fibroblasts; MM6; CD4T; peripheral-blood; MSC; TIME; endometrial; GSCs
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000355622.8; ENST00000646089.1; ENST00000645071.1; ENST00000472304.2; ENST00000642985.1; ENST00000394487.5
External Link RMBase: m6A_site_835762
mod ID: M6ASITE089446 Click to Show/Hide the Full List
mod site chr9:117714663-117714664:+ [6]
Sequence TCTGAAGAGGAAAAATAAAAACCTCCTGAGGCATTTCTTGC
Motif Score 2.185083333
Cell/Tissue List fibroblasts; MM6; CD4T; peripheral-blood; GSC-11; MSC; TIME; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000394487.5; ENST00000642985.1; ENST00000645071.1; ENST00000472304.2; ENST00000646089.1; ENST00000355622.8
External Link RMBase: m6A_site_835763
mod ID: M6ASITE089447 Click to Show/Hide the Full List
mod site chr9:117715546-117715547:+ [6]
Sequence GCTTCCTGGTCTTATCATGGACAATTTGGGCTAGAGGCAGG
Motif Score 3.643047619
Cell/Tissue List fibroblasts; GM12878; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000645071.1; ENST00000646089.1; ENST00000394487.5; ENST00000642985.1; ENST00000355622.8
External Link RMBase: m6A_site_835764
mod ID: M6ASITE089448 Click to Show/Hide the Full List
mod site chr9:117715614-117715615:+ [4]
Sequence ACCTTTTCTTGATTCCAGAAACATATGGGCTGATAAACCCG
Motif Score 2.20572619
Cell/Tissue List HeLa; U2OS; fibroblasts; GM12878; MSC; TIME; TREX
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000394487.5; ENST00000642985.1; ENST00000646089.1; ENST00000645071.1; ENST00000355622.8
External Link RMBase: m6A_site_835765
mod ID: M6ASITE089449 Click to Show/Hide the Full List
mod site chr9:117715630-117715631:+ [4]
Sequence AGAAACATATGGGCTGATAAACCCGGGGTGACCTCATGAAA
Motif Score 2.185083333
Cell/Tissue List HeLa; U2OS; fibroblasts; GM12878; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000646089.1; ENST00000642985.1; ENST00000394487.5; ENST00000355622.8; ENST00000645071.1
External Link RMBase: m6A_site_835766
mod ID: M6ASITE089450 Click to Show/Hide the Full List
mod site chr9:117715682-117715683:+ [4]
Sequence AGAAGTTTATTTTTTTCAGAACAAGTGATGTTTGATGGACC
Motif Score 2.951386905
Cell/Tissue List HeLa; U2OS; fibroblasts; GM12878; peripheral-blood; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000355622.8; ENST00000394487.5; ENST00000642985.1; ENST00000646089.1; ENST00000645071.1
External Link RMBase: m6A_site_835767
mod ID: M6ASITE089451 Click to Show/Hide the Full List
mod site chr9:117715700-117715701:+ [7]
Sequence GAACAAGTGATGTTTGATGGACCTCTGAATCTCTTTAGGGA
Motif Score 3.622404762
Cell/Tissue List U2OS; GM12878; peripheral-blood; MSC; TIME; TREX; endometrial
Seq Type List MeRIP-seq; m6A-seq
Transcript ID List ENST00000645071.1; ENST00000394487.5; ENST00000355622.8; ENST00000646089.1; ENST00000642985.1
External Link RMBase: m6A_site_835768
mod ID: M6ASITE089452 Click to Show/Hide the Full List
mod site chr9:117715722-117715723:+ [7]
Sequence CTCTGAATCTCTTTAGGGAGACACAGATGGCTGGGATCCCT
Motif Score 2.897386905
Cell/Tissue List U2OS; peripheral-blood; MSC; TIME
Seq Type List MeRIP-seq; m6A-seq
Transcript ID List ENST00000645071.1; ENST00000642985.1; ENST00000646089.1; ENST00000394487.5; ENST00000355622.8
External Link RMBase: m6A_site_835769
mod ID: M6ASITE089454 Click to Show/Hide the Full List
mod site chr9:117715771-117715772:+ [7]
Sequence CCCTTCTCACTGCCAGGAGAACTACGTGTGAAGGTATTCAA
Motif Score 3.373380952
Cell/Tissue List U2OS; peripheral-blood; MSC; TIME
Seq Type List MeRIP-seq; m6A-seq
Transcript ID List ENST00000646089.1; ENST00000645071.1; ENST00000394487.5; ENST00000355622.8; ENST00000642985.1
External Link RMBase: m6A_site_835770
mod ID: M6ASITE089455 Click to Show/Hide the Full List
mod site chr9:117715875-117715876:+ [4]
Sequence TGGATGTTATCATTGAGAAAACAATGTGTCTGGAATTAATG
Motif Score 2.20572619
Cell/Tissue List HeLa; peripheral-blood; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000355622.8; ENST00000646089.1; ENST00000645071.1; ENST00000642985.1
External Link RMBase: m6A_site_835771
mod ID: M6ASITE089456 Click to Show/Hide the Full List
mod site chr9:117715950-117715951:+ [4]
Sequence TTCATCCAGCCTCCTCAGAAACAGAACATTCAAGAAAAGGA
Motif Score 2.20572619
Cell/Tissue List HeLa; fibroblasts; GM12878; peripheral-blood; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000645071.1; ENST00000646089.1; ENST00000642985.1; ENST00000355622.8
External Link RMBase: m6A_site_835772
mod ID: M6ASITE089457 Click to Show/Hide the Full List
mod site chr9:117715955-117715956:+ [4]
Sequence CCAGCCTCCTCAGAAACAGAACATTCAAGAAAAGGACAATC
Motif Score 2.951386905
Cell/Tissue List HeLa; fibroblasts; GM12878; peripheral-blood; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000642985.1; ENST00000646089.1; ENST00000355622.8; ENST00000645071.1
External Link RMBase: m6A_site_835773
mod ID: M6ASITE089458 Click to Show/Hide the Full List
mod site chr9:117715970-117715971:+ [4]
Sequence ACAGAACATTCAAGAAAAGGACAATCAGGATGTCATCAGGG
Motif Score 3.643047619
Cell/Tissue List HeLa; fibroblasts; GM12878; peripheral-blood; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000646089.1; ENST00000642985.1; ENST00000645071.1; ENST00000355622.8
External Link RMBase: m6A_site_835774
mod ID: M6ASITE089459 Click to Show/Hide the Full List
mod site chr9:117716005-117716006:+ [4]
Sequence TCAGGGAAATGAAAATAAAAACCACAATGAGATATCACCTT
Motif Score 2.185083333
Cell/Tissue List HeLa; fibroblasts; GM12878; peripheral-blood; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List rmsk_2862015; ENST00000355622.8; ENST00000645071.1; ENST00000642985.1; ENST00000646089.1
External Link RMBase: m6A_site_835775
mod ID: M6ASITE089460 Click to Show/Hide the Full List
mod site chr9:117716088-117716089:+ [6]
Sequence AAGGATATAGAGAAATTGGAACCCTTCTTCACTGCTGGAGG
Motif Score 2.930744048
Cell/Tissue List fibroblasts; A549; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List rmsk_2862015; ENST00000355622.8; ENST00000642985.1; ENST00000645071.1; ENST00000646089.1
External Link RMBase: m6A_site_835776
mod ID: M6ASITE089461 Click to Show/Hide the Full List
mod site chr9:117716139-117716140:+ [6]
Sequence TGGTGTAGCCGTTATGAAAAACAGTACGGAGGTTTCTCAAA
Motif Score 2.20572619
Cell/Tissue List fibroblasts; A549; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000645071.1; ENST00000642985.1; ENST00000355622.8; rmsk_2862015; ENST00000646089.1
External Link RMBase: m6A_site_835777
mod ID: M6ASITE089462 Click to Show/Hide the Full List
mod site chr9:117716173-117716174:+ [6]
Sequence TCTCAAAAATTAAAAATAGAACTGCTATATGATCCAGCAAT
Motif Score 3.373380952
Cell/Tissue List fibroblasts; A549; GM12878; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000355622.8; ENST00000642985.1; rmsk_2862015; ENST00000646089.1; ENST00000645071.1
External Link RMBase: m6A_site_835778
mod ID: M6ASITE089463 Click to Show/Hide the Full List
mod site chr9:117716306-117716307:+ [6]
Sequence CTGTTTCCAAAGTTATGGAAACAACCCAAATTTCCATTGAA
Motif Score 2.20572619
Cell/Tissue List fibroblasts; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000646089.1; rmsk_2862015; ENST00000642985.1; ENST00000645071.1; ENST00000355622.8
External Link RMBase: m6A_site_835779
mod ID: M6ASITE089465 Click to Show/Hide the Full List
mod site chr9:117716337-117716338:+ [6]
Sequence TTCCATTGAAAAATAAATGGACAAAGAAAATGTGCATATAC
Motif Score 3.643047619
Cell/Tissue List fibroblasts; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000642985.1; ENST00000646089.1; ENST00000355622.8; ENST00000645071.1; rmsk_2862015
External Link RMBase: m6A_site_835780
mod ID: M6ASITE089466 Click to Show/Hide the Full List
mod site chr9:117716423-117716424:+ [6]
Sequence ATTTATGACAACATGAATAAACCCGGAGGCCATTATGCTAT
Motif Score 2.185083333
Cell/Tissue List fibroblasts; MSC; TIME
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000646089.1; ENST00000642985.1; rmsk_2862015; ENST00000645071.1; ENST00000355622.8
External Link RMBase: m6A_site_835781
mod ID: M6ASITE089467 Click to Show/Hide the Full List
mod site chr9:117716468-117716469:+ [6]
Sequence AATGAGCAAGTAACAGAAAGACAAATACTGCCTGATTTCAT
Motif Score 2.897386905
Cell/Tissue List fibroblasts
Seq Type List m6A-seq
Transcript ID List ENST00000646089.1; ENST00000642985.1; rmsk_2862015; ENST00000355622.8; ENST00000645071.1
External Link RMBase: m6A_site_835782
mod ID: M6ASITE089468 Click to Show/Hide the Full List
mod site chr9:117716514-117716515:+ [6]
Sequence TGAGGTTCTAAAATAGTCAAACTCATAGAAGCAGAGAATAG
Motif Score 2.627720238
Cell/Tissue List fibroblasts
Seq Type List m6A-seq
Transcript ID List ENST00000642985.1; ENST00000355622.8; ENST00000646089.1; rmsk_2862015; ENST00000645071.1
External Link RMBase: m6A_site_835783
mod ID: M6ASITE089469 Click to Show/Hide the Full List
mod site chr9:117716536-117716537:+ [6]
Sequence TCATAGAAGCAGAGAATAGAACAGTGGTTCCTAGGGAAAAG
Motif Score 2.951386905
Cell/Tissue List fibroblasts
Seq Type List m6A-seq
Transcript ID List ENST00000642985.1; ENST00000646089.1; rmsk_2862015; ENST00000645071.1; ENST00000355622.8
External Link RMBase: m6A_site_835784
mod ID: M6ASITE089470 Click to Show/Hide the Full List
mod site chr9:117716666-117716667:+ [6]
Sequence TAGCAGAGTTCGTATAATGAACAATACTGTATTATGCACTT
Motif Score 2.951386905
Cell/Tissue List fibroblasts
Seq Type List m6A-seq
Transcript ID List ENST00000642985.1; ENST00000645071.1; ENST00000646089.1; ENST00000355622.8; rmsk_2862015
External Link RMBase: m6A_site_835785